Clinical trials: Middle Ear Effusion
Otitis Media Acute
Otitis Treatment With OtoSight™ - Modification of Antibiotic Treatment Intervention in Children
A pragmatic, mixed-method trial is to show the ability of OtoSight to change management of the pediatric patient presenting with ear pain in a way that improves patient outcomes and reduces costs.
- Trial name
- OTO-MATIC (NCT06285812)
- Testing
- OtoSight Middle Ear Scope
- Where
- 7 sites in United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- PhotoniCare, Inc.
Otitis Media With Effusion
Wideband Tympanometry in Otitis Media With Effusion
The investigators asked the question if they can better estimate the middle ear status in OME that help them to decide between early intervention or longer follow up.
- Trial name
- NCT04395261
- Testing
- Wideband Tympanometry
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Otitis Media With Effusion
A Novel Objective Diagnostic Test for Otitis Media With Effusion
Otitis media with effusion (OME) cases refer to a clinically silent condition. Otoscopic findings are subjective and not always reliable. As an objective test tympanometric evaluation is imperfect for diagnosis of OME.
- Trial name
- NCT02179541
- Testing
- RGB
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Nazan Degirmenci
Hearing Loss, Bilateral or Unilateral, Otitis Media With Effusion in Children
Towards Implementation of Universal Newborn Hearing Screening in Kenya
The goal of this observational study is to learn if smartphone hearing screening devices can help to understand the role of ear infections in hearing loss in infants with HIV exposure.
- Trial name
- mTUNE-R33 (NCT07879326)
- Testing
- Hearing and ear health screening
- Where
- Kenya
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Washington
Adenoid Hypertrophy, Middle Ear Effusion
It is Accepted That Adenoid Hypertrophy is Related to Otitis Media With Effusion Incidence. Better Understanding of the Correlation Between the Relative Size of AH and the Incidence of Persistent OME May Provide Evidence to Support a More Standardized Approach to the Diagnosis and Treatment of OME.
The aim of this study is to further investigate the correlation between Site and size of adenoid hypertrophy and middle ear effusion in order to provide evidence for designing a more standardized approach to the diagnosis and…
- Trial name
- NCT06674720
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Otitis Media Acute
Clinical Development of Deep Learning for the OtoSight
The objective of this study is to clinically develop and evaluate a machine learning approach to improve the performance and data interpretation of the PhotoniCare OtoSight Middle Ear Scope in pediatric patients presenting at the…
- Trial name
- NCT04722770
- Testing
- PhotoniCare OtoSight Middle Ear Scope
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- PhotoniCare, Inc.
Middle Ear Effusion, Tympanic Membrane Perforation
PneuMum: Pneumococcal Vaccination of Australian Indigenous Mothers to See if it Protects Their Babies From Ear Disease
PneuMum is a randomised controlled trial that aims to find out if pneumococcal vaccination for Australian Indigenous mothers, in the last few months of pregnancy or at delivery, can prevent ear disease in infants.
- Conditions
- Middle Ear Effusion, Tympanic Membrane Perforation, Acute Otitis Media, Pneumococcal Infections
- Trial name
- NCT00310349
- Testing
- 23 valent pneumococcal polysaccharide vaccine
- Where
- Australia
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Otitis Media
Long-term Antibiotics for Treatment and Prevention of Otitis Media in Aborignal Children
This clinical trial was conducted in a population where tympanic membrane perforation occurs in 60% infants in the first year of life.
- Trial name
- COMIT1 (NCT00539149)
- Testing
- Amoxycillin
- Where
- Australia
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Menzies School of Health Research
Otitis Media, Conductive Hearing Loss
The Influence of The Ear Popper on Serous Otitis Media and on the Accompanying Conductive Hearing Loss in Children
This study is designed to check the effect of the use of the ear popper device on serous otitis media in children and on the conductive hearing loss accompanying the otitis.
- Trial name
- NCT00393159
- Testing
- Ear Popper
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Otitis Media
Eustachian Tube Growth and Development
This study is to measure over time (from 3 years until 13 years of age) Eustachian tube function (the way the Eustachian tube works) and facial growth in groups of children with two types of middle-ear disease and with little…
- Trial name
- NCT00422929
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Otitis Media With Effusion, Eustachian Tube Disorder
Novel Imaging of the Eustachian Tube; Patient Study
The purpose of the study is to establish wether a contrast medium applied to the middle ear can be used to diagnose pathology in the auditory tube.
- Trial name
- CT-ET (NCT02282540)
- Testing
- Iodixanol to the Eustachian tube
- Where
- Norway
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Otitis Media With Effusion, Adenoid Hypertrophy
The Effects of Exosomes in Otitis Media With Effusion
The particularity of adenoids, as a reservoir of bacterial pathogens and immune molecules, is known to be significantly involved in children with otitis media with effusion (OME).
- Trial name
- NCT05402267
- Testing
- Adenoidectomy
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Middle Ear Effusion, Tympanic Membrane Perforation
PneuMum: Pneumococcal Vaccination of Australian Indigenous Mothers
PneuMum is a randomised controlled trial that aims to find out if pneumococcal vaccination for Australian Indigenous mothers, in the last few months of pregnancy or at delivery, can prevent ear disease in infants.
- Conditions
- Middle Ear Effusion, Tympanic Membrane Perforation, Acute Otitis Media, Pneumococcal Infections
- Trial name
- PneuMum (NCT00714064)
- Testing
- 23vPPV, dTpa (Pneumovax, Boostrix)
- Where
- Australia
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Menzies School of Health Research
Hearing Loss, Sensorineural, Hearing Loss, Conductive
Wide Frequency Band Test of Hearing in Veterans
The accurate assessment of auditory status is critical for planning treatment for Veterans with hearing loss to include medical and audiological management.
- Conditions
- Hearing Loss, Sensorineural, Hearing Loss, Conductive, Hearing Loss, Mixed Conductive-Sensorineural, Otosclerosis
- Trial name
- CWTBAFV (NCT02019888)
- Where
- 2 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Otitis Media With Effusion, Hearing Loss
Autoinflation: Alternative in the Treatment of Otitis Media With Effusion
Otitis media with effusion (OME) is a common finding affecting children and the main cause of acquired hearing loss in the pediatric age.
- Trial name
- OME (NCT05324696)
- Testing
- autoinflation device
- Where
- Portugal
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Instituto de Ciências Biomédicas Abel Salazar
Chronic Serous Otitis Media, Simple or Unspecified
Prevalence of Mucosal Biofilm Formations in Adenoidectomy Specimens
Rationale: Bacterial biofilms are defined as an assemblage of bacterial cells enclosed in a self-produced glycocalyx matrix. Adherence on surfaces, and resistance to both antibiotic treatments and host defenses are ones of the…
- Trial name
- BOLERO (NCT01022944)
- Testing
- With chronic middle ear effusion, Without chronic middle ear effusion
- Where
- France
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hearing Loss, Conductive
Testing a New App for Children With Glue Ear
To assess whether children with glue ear ( and some normal hearing controls) and their families find the Hear Glue Ear application acceptable and easy to use.
- Trial name
- NCT06256081
- Testing
- Hear Glue ear application
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Tamsin Brown
Otitis Media, Middle Ear Effusion
Middle Ear Disease Before Age 3, Treatment With Ear Tubes, and Literacy and Attentional Abilities at Ages 9 to 11
Middle-ear disease (infection and fluid) is the most common illness in young children after the common cold. Because hearing loss accompanies middle-ear disease, and because early life is a period of rapid development, concern…
- Trial name
- NCT00365092
- Testing
- Insertion of tympanostomy tubes
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hearing Loss, Otitis Media With Effusion
Sound Ear Check (SEC) in Hearing Diagnostics in Young Children
Study Sound Ear Check (SEC) hearing test among 3-10 years old otherwise healthy children referred to tympanostomy tube placement.
- Conditions
- Hearing Loss, Otitis Media With Effusion, Tympanostomy
- Trial name
- NCT05535634
- Testing
- Sound Ear Check
- Where
- Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vesa Lahdes
Chronic Otitis Media With Effusion, Conductive Hearing Loss
Montelukast for Children With Chronic Otitis Media With Effusion (COME): A Double-blind, Placebo-controlled Study
The purpose of our double-blind, placebo controlled study is to test the hypothesis that montelukast therapy might be associated with improved hearing in certain sub populations of children suffering from OME.
- Trial name
- COME (NCT01967498)
- Testing
- Montelukast
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center