Clinical trials: Mifepristone
Medical Abortion
Routine Follow-up Versus Self-assessment in Medical Abortion
The main objective of the study is to optimize the routines for follow-up after medical abortion in order to give women more autonomy by reducing the number of consultations involved and to reduce the frequency of postabortal…
- Trial name
- NCT01487213
- Testing
- Home self assessment of complete medical abortion
- Where
- 4 sites in Austria, Finland and 2 more
- Volunteers
- 929 people
- Sponsor
- Karolinska Institutet
Mild Hypercortisolism
Glucocorticoid Receptor Blockade With Mifepristone in Patients With Mild Adrenal Hypercortisolism
The purpose of this study is to determine whether mifepristone is an effective treatment for hyperglycemia due to mild hypercortisolism.
- Trial name
- NCT01990560
- Testing
- Mifepristone
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Induced Abortion
Same-Day Mifepristone-Misoprostol Compared to Misoprostol Only for Surgical Abortion Cervical Preparation
A randomized double---blinded comparison of same---day mifepristone and misoprostol with misoprostol only for cervical preparation in second---trimester surgical abortion in 100 women at 14 0/7---19 6/7 weeks gestation.
- Trial name
- MMSAP (NCT02412618)
- Testing
- Mifepristone, Misoprostol
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Complete Abortion
Mifepristone and Misoprostol for the Termination of Pregnancy up to 70 Days' Gestation in Kazakhstan
The study will be conducted in 4 sites and will examine how a simplified outpatient medical abortion procedure using mifepristone and misoprostol, with the option to take mifepristone at a place of woman's choosing, works in…
- Trial name
- NCT02018796
- Testing
- Mifepristone, misoprostol
- Where
- 4 sites in Kazakhstan
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Pregnancy Related, Abortion Early
Medication Abortion Via Pharmacy Dispensing
This mixed-methods study follows a prospective cohort of patients receiving Mifeprex ® (mifepristone) for medication abortion dispensed by pharmacists after undergoing standard clinical evaluation.
- Trial name
- NCT03320057
- Testing
- Mifepristone, Training on mifepristone dispensing
- Where
- 6 sites in United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Daniel Grossman
Psychotic Disorders, Depressive Disorder, Major
Treatment of Schizoaffective Disorder Using Mifepristone
This study tests the hypothesis that mifepristone will diminish cognitive distortion and alleviate psychosis in patients with schizoaffective disorder.
- Conditions
- Psychotic Disorders, Depressive Disorder, Major, Depressive Disorder
- Trial name
- NCT00725270
- Testing
- Mifepristone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
Abortion, Second Trimester
24-hour Mifepristone and Buccal Versus Mifepristone and Vaginal Misoprostol for Cervical Preparation for D&E
This study aims to compare mifepristone and buccal misoprostol to mifepristone and vaginal misoprostol for cervical preparation for second trimester dilation and evacuation (D\&E).
- Trial name
- NCT03134183
- Testing
- Vaginal Misoprostol, Buccal Misoprostol
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Pregnancy Early, Pregnancy Related
Assessing the Efficacy and Acceptability of Two Missed Period Pills Regimens
The goal of this trial is to examine the efficacy and acceptability of two medication regimens at inducing a return of menses when used 2-8 days after a missed period.
- Trial name
- NCT06492889
- Testing
- Levonorgestrel, Mifepristone
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion
Mifepristone Versus Laminaria Insertion for Cervical Preparation Prior to Surgical Abortion at 14-16 Weeks
Women who are requesting pregnancy termination at 14-16 weeks, who would normally have osmotic dilator insertion the day before their procedure, would be asked if they wanted to participate.
- Trial name
- SAMi (NCT00986921)
- Testing
- mifepristone 200 mg, osmotic dilator insertion
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston University
Abortion
Mifepristone and Misoprostol for Undesired Pregnancy of Unknown Location
Patients who seek medication abortion early in pregnancy may have an ultrasound that does not show a pregnancy in the uterus. This is known as a "pregnancy of unknown location".
- Trial name
- NCT05839899
- Testing
- Mifepristone plus one dose Misoprostol, Mifepristone plus two doses Misoprostol
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood League of Massachusetts
Complete Abortion
Study on Combined Use of Letrozole, Mifepristone and Misoprostol in Termination of Pregnancy
By using the combination of mifepristone (anti-progestin), misoprostol (progstanglandin which stimulates uterine contraction), and letrozole (aromatise inhibitor which reduces estrogen production), the abortion process will be…
- Trial name
- NCT01475318
- Testing
- mifepristone, Letrozole, Misoprostol
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Missed Menstrual Period
Assessing Use Of Mifepristone After Progestin Priming For Use As "Missed Period Pills"
This study will assess the effectiveness and acceptability of a 3-day missed period pill regimen.
- Trial name
- NCT04676776
- Testing
- Levonorgestrel, Mifepristone
- Where
- Mexico
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Healthy Subjects
A Phase I Study to Determine the Effect of Mifepristone on the Pharmacokinetics of Fluvastatin in Healthy Volunteers
This study is to determine the effect of single and multiple oral doses of mifepristone on the pharmacokinetics of a single oral dose of fluvastatin administered to healthy volunteers.
- Trial name
- NCT00752843
- Testing
- mifepristone + fluvastatin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Corcept Therapeutics
Meningioma
S9005 Mifepristone in Meningioma
To compare daily oral mifepristone vs placebo with respect to time to treatment failure in patients with unresectable meningioma.
- Trial name
- NCT03015701
- Testing
- Mifepristone
- Volunteers
- 193 people
- Sponsor
- SWOG Cancer Research Network
Second Trimester Labor Induction
Second Trimester Labor Induction
A superior second trimester medical abortion regimen has not been identified. Studies suggest that a regimen of mifepristone and misoprostol given 36 to 48 hours apart has the shortest median induction-to-abortion interval…
- Trial name
- NCT00592215
- Testing
- Experimental (mifepristone and misoprostol)
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Silent Miscarriage
Letrozole Versus Mifepristone and Misoprostol in Silent Miscarriage
Management of first trimester silent miscarriage can be by expectant, medical or surgical management. Surgical management by suction evacuation is associated with surgical risks (including risks to the womb that can affect…
- Trial name
- NCT06733727
- Testing
- Letrozole, Mifepristone
- Volunteers
- 884 people
- Sponsor
- The University of Hong Kong