Clinical trials: Migraine, completed
Headache, Migraine, Chronic Migraine Headache
Stellate Ganglion Blockade for Refractory Chronic Migraine
Stellate Ganglion Block (SGB) is an interventional anesthetic technique used to treat pain conditions affecting the head, face, neck, and upper extremities by temporarily blocking sympathetic nerve output.
- Trial name
- SGB-RCM (NCT06891118)
- Testing
- Procedure/Surgery: Ultrasound-Guided Stellate Ganglion Block
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ankara City Hospital Bilkent
Migraine
A Study to Compare the Blood Levels of Two Dosage Formulations of the Study Medicine in Healthy Adults
The purpose of this study is to assess the bioequivalence of an alternative ODT formulation (ODT2) versus the approved ODT formulation of a CGRP receptor antagonist in healthy adult participants under fasting conditions.
- Trial name
- NCT07594769
- Testing
- ODT2 Test formulation, ODT Reference formulation
- Where
- Belgium
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pfizer
Migraine
A Study to Learn About the Safety and Effects of Rimegepant to Prevent Migraine in Chinese Subjects.
The purpose of this study is to learn about the effects of Rimegepant to help prevent migraine. This study is seeking for participants who: Are male and female of 18 years of age or older.
- Trial name
- NCT05810038
- Testing
- Rimegepant
- Where
- 49 sites in China
- Volunteers
- 787 people
- Sponsor
- Pfizer
Migraine
Effects of Prayer on Pain Thresholds and Scores of Anxiety and Depression in Participants With and Without Migraine
This study comprised two separate assessor-blinded randomized crossover experiments, one in participants with migraine and one in participants without migraine.
- Trial name
- NCT07143461
- Testing
- Prayer Condition, Reading Condition
- Where
- Brazil
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Chronic Migraine Headache
Efficacy of Traditional Integrated Islamic Psychotherapy and Cognitive Behavioural Therapy for Migraine: A Randomized Controlled Trial
his randomized controlled trial aims to evaluate the efficacy of Cognitive Behavioral Therapy (CBT) and Traditional Integrated Islamic Psychotherapy (TIIP) as psychological interventions for individuals with chronic migraine.
- Trial name
- CBT TIIP (NCT07802912)
- Testing
- Cognitive Behavioral Therapy (CBT), Traditional Integrated Islamic Psychotherapy (TIIP), Medication Group
- Where
- Pakistan
- Volunteers
- 45 people
- Sponsor
- GIFT University
Migraine
Improving the Perception of Stress and Mutuality in Caregivers (MI-DEAR Study) of Migraine Patients With Depressive Symptoms Treated With Fremanezumab: A Study to Evaluate Whether Fremanezumab Reduces the Impact on Caregivers and Increases Couple Reciprocity
To evaluate the reduction of emotional burden (measured by Relative Stress Scale-RSS) of caregivers of migraine patients with Depressive Symptoms after 6 months after the first injection of fremanezumab.
- Trial name
- NCT07029126
- Testing
- Fremanezumab
- Where
- 10 sites in Italy
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Migraine
Effect of Transcutaneous Auricular Trigeminal Nerve Stimulation on Migraine
This randomized, sham-controlled, and assessor and participants-blind clinical study aims to investigate the effects of transcutaneous auricular trigeminal nerve stimulation (taTNS) on intensity of headache, sleep quality, level…
- Trial name
- NCT07457268
- Testing
- Transcutaneous Auricular Trigeminal Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Ordu University
Chronic Migraine; Multiple Sclerosis; Motoneuron Disease
Feasibility and Effectiveness of a Mindfulness Program Delivered by Web to Patients During Hospitalization and Caregivers.
Hospitalization is often a traumatic event so stressful for the life of patients. Isolation, loneliness, worries about clinical examinations, results from examinations and final diagnosis, uncertainty about the future are the…
- Trial name
- KIMPO (NCT05623254)
- Testing
- no comparator - TAU (Treatment-as-usual)
- Where
- Italy
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Chronic Migraine
Brief Interventions in Chronic Migraine
People with chronic migraine headaches face many challenges, including high levels of daily pain, disturbances to everyday activities and sleep, and problems with mood such as depression or anxiety.
- Trial name
- NCT05979337
- Testing
- Empowered Relief, Health Education (HE), Treatment as Usual
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Michigan
Migraine, Menstrual Migraine
Fremanezumab Treatment of Migraine in Women With Menstrual Migraine Ages 18-45
The goal of this clinical trial is to learn about how a migraine prevention medicine works for people who have migraines/headaches with their menstrual period.
- Conditions
- Migraine, Menstrual Migraine, Menstrually Related Migraine
- Trial name
- NCT06173661
- Testing
- Fremanezumab
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Brigham and Women's Hospital
Migraine
Music and Imagery for Veterans With Migraine Headache
The purpose of this study is to determine feasibility and acceptability of telehealth music imagery for migraine (Aim 1) and to explore whether there are clinically meaningful changes in headache frequency and associated…
- Trial name
- IMAGINE (NCT06440876)
- Testing
- Music and Imagery
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Richard L. Roudebush VA Medical Center
Primary Headaches (Includes Migraines, Tension, Cluster Headaches)
Personalised Process-based Psychological Interventions for Paediatric Headaches
This project was an empirical single-case experimental design (SCED) study conducted as part of a DClinPsy doctoral thesis completed by one of the researchers.
- Trial name
- HEAD-FLEX (NCT07418723)
- Testing
- PBT Personalised
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- Royal Holloway University
Headache, Migraine, Manuel Therapy
The Effect of Two Different Massages on Migraine
The study aims to compare the effects of connective tissue massage on pain severity, attack frequency and duration, migraine-related disability, and quality of life in patients diagnosed with migraine, by comparing them with the…
- Trial name
- NCT05452330
- Testing
- Connective tissue massage, Classical massage
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Biruni University
Migraine Disorders
Botulinum Toxin Type A Blockade of the Sphenopalatine Ganglion in Treatment-refractory Chronic Migraine
This is a clinical trial to assess the efficacy of botox treatment of the sphenopalatine ganglion as an add-on treatment in drug resistant migraine.
- Trial name
- MiBlock (NCT04069897)
- Testing
- Botulinum toxin type A
- Where
- 4 sites in Norway
- Volunteers
- 170 people
- Sponsor
- St. Olavs Hospital
Meniere's Disease, Benign Paroxysmal Positional Vertigo
CAVA: Dizziness Trial
Clinical investigation of a medical device (CAVA) for recording eye movements. Patients suffering from diagnosed dizziness conditions will wear the device for 23 hours a day, for 30 days.
- Conditions
- Meniere's Disease, Benign Paroxysmal Positional Vertigo, Recurrent Vestibulopathy, Vestibular Migraine
- Trial name
- CAVA (NCT04026516)
- Testing
- CAVA Device
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Insomnia, Migraine Disorders
Intervention for Sleep and Pain in Youth: A Randomized Controlled Trial
Insomnia is a common comorbidity among adolescents with migraine. This randomized controlled clinical trial aims to determine efficacy of cognitive-behavioral therapy (CBT) for insomnia, as well as the combined effect of CBT…
- Conditions
- Insomnia, Migraine Disorders, Headache Disorders
- Trial name
- I-SPY-RCT (NCT04936321)
- Testing
- Internet-delivered CBT for Insomnia, Internet-delivered CBT for Pain Management, Internet-delivered Sleep Education
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Seattle Children's Hospital
Migraine
Effectiveness of Manual Lymphatic Drainage in the Physiotherapeutic Treatment of Migraine
Migraine is a highly prevalent neurological disorder associated with recurrent headache, disability, and reduced quality of life.
- Trial name
- EDLMMG (NCT07425041)
- Testing
- Manual lymphatic drainage
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Camilo Jose Cela University
Migraine
A Trial to Test if Fremanezumab is Effective in Preventing Migraine in Children and Adolescents
The primary objective of the study is to evaluate the long-term safety and tolerability of subcutaneous fremanezumab in the preventive treatment of migraine in pediatric participants 6 to 17 years of age (inclusive at enrollment…
- Trial name
- NCT04530110
- Testing
- Fremanezumab
- Where
- 70 sites in United States, Canada and 7 more
- Volunteers
- 499 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D LLC
Migraine, Nocebo Effects
Default Mode Network Connectivity and Nocebo Responses in Migraine: A Functional MRI Study
People with migraine sometimes experience symptoms because they expect a treatment to cause side effects. This is known as the "nocebo effect".
- Trial name
- Does not exist (NCT07720895)
- Testing
- intravenous saline infusion, Negative verbal suggestion, No intervention
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Ioanna Spanou
Migraine
A Clinical Trial Evaluated the Safety and Tolerability, Pharmacokinetic and Pharmacodynamics Profile, and Immunogenicity of a Single Dose of JS010 Injection in Healthy Subjects
This study adopts a dose escalation design with six preset dose levels, namely 3mg, 30mg, 150mg, 300mg,600mg, 900mg, single subcutaneous injection.
- Trial name
- NCT06158737
- Testing
- JS010 injection
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Shanghai Junshi Bioscience Co., Ltd.