Clinical trials: Migraine, completed
Migraine
Study of Oral Lasmiditan in Participants With Normal and Impaired Renal Function
This is a multi-center, open-label, non-randomized, parallel-group, adaptive, single dose study. This study will enroll up to 32 participants using an adaptive design that can include up to 3 groups of 8 participants with…
- Trial name
- NCT03009162
- Testing
- Lasmiditan
- Where
- 2 sites in Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Migraine
Effectiveness of a Dialogue-based Online Intervention Against Migraine
This trial was designed to evaluate the effectiveness of a dialogue-based online intervention (ceprica) that provides information regarding cognitive behavioural therapy (CBT) in patients with migraine.
- Trial name
- EU-OPTMi (NCT04276142)
- Testing
- ceprica (additional to treatment as usual), active control intervention (additional to treatment as usual)
- Where
- Germany
- Volunteers
- 321 people
- Sponsor
- Gaia AG
Migraine
Effects of Adding an Oculomotor Therapy Treatment in Patients With Migraine
Headaches are the fourth cause/reason for disability in the world population. Of which, headache in general accounts for 47%, 38% are tension headaches, 10% migraines and 3% for chronic headache lasting more than 15 days a month.
- Trial name
- NCT05842642
- Testing
- Cervical, Oculomotor
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- University of Jaén
Migraine
A Prospective Real World Study of Rimegepant in the Treatment of Migraine
The goal of this observational study is to test the effectiveness and safety of Rimegepant in the treatment of migraine patients in real world.
- Trial name
- NCT05709106
- Testing
- Rimegepant 75 MG
- Where
- China
- Volunteers
- 173 people
- Sponsor
- Ruijin-Hainan Hospital Shanghai Jiao Tong University School Of Medicine
Migraine
Study to Evaluate the Efficacy and Safety of Erenumab (AMG 334) Compared to Placebo in Migraine Prevention
To evaluate the effect of erenumab compared to placebo on the change from baseline in monthly migraine days, in adults with episodic migraine.
- Trial name
- ARISE (NCT02483585)
- Testing
- Erenumab
- Where
- 76 sites in United States, Denmark and 6 more
- Volunteers
- 577 people
- Sponsor
- Amgen
Chronic Migraine
Intramuscular Electrical Stimulation for the Treatment of Trigger Points in Patients With Migraine
The goal of this single-case experimental study is to investigate the effects of intramuscular electrical stimulation for the treatment of trigger points on reducing the frequency of headaches in a small sample of patients with…
- Trial name
- NCT05893914
- Testing
- Dry Needling and intramuscular electrical stimulation to trigger points
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Thomas W. Perreault, PT
Migraine
Rizatriptan in Acute Treatment of Migraine in Patients With Unilateral Trigeminal-autonomic Symptoms.
Triptans are first choice drugs in the acute treatment of migraine and cluster headache. However, while in cluster headache the response rate to subcutaneous sumatriptan is 96%, around 30% of patients fail to respond to a…
- Trial name
- NCT00753311
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- IRCCS San Raffaele
Migraine
Acetaminophen and Ibuprofen With and Without Magnesium and Primary Migraine in Childhood
Aim: The purpose of this study was to evaluate both the effects of ibuprofen and/or acetaminophen for the acute treatment of primary migraine in children in or out prophylactic treatment with magnesium.
- Trial name
- NCT01756209
- Testing
- Magnesium 400Mg, Ibuprofen 10 mg/kg, acetaminophen 15 mg/kg
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- University of Catanzaro
Chronic Pain, Headache, Migraine
Feasibility of Using Holographic Memory Resolution® (HMR) in Patients/Clients With Pain
Study Purpose: This study will explore the feasibility of administering Holographic Memory Resolution® (HMR) to adults who are experiencing chronic pain for 6 months or more.
- Conditions
- Chronic Pain, Headache, Migraine, Stress Disorders, Post-Traumatic
- Trial name
- NCT05001399
- Testing
- Holographic Memory Resolution® (HMR)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Billings Clinic
Migraine, Migraine Disease
Diaphragm Relaxation Techniques, Diaphragmatic Breathing Exercises for Migraine Patients
Migraine is a neurological disease characterized by recurring headaches. It is a significant public health problem of the top reasons for disability throughout the world.
- Conditions
- Migraine, Migraine Disease, Manuel Therapy, Diaphragm Relaxation
- Trial name
- NCT07145372
- Testing
- Manual therapy, Diaphragmatic relaxation technique, Shoulder ROM exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Seda Saka
Central Sensitisation, Migraine
Presence of Signs of Central Sensitization in Episodic and Chronic Migraine
Nowadays migraine is conceptualized as a continuum, with at the one hand episodic migraine (EM) and at the other hand chronic migraine (CM) (1).
- Trial name
- CENSENMI (NCT05162664)
- Testing
- Pressure pain thresholds, Thermal detection and pain thresholds, Temporal summation
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Ghent
Chronic Migraine, Chronic Headache
Biobehavioral Physical Therapy Strategies Based on Therapeutic Exercise Applied to Chronic Migraine Patients
The purpose of this study is to know wich combination of treatments are the most effective in patients with chronic migraine. The study design is a simple blind randomized controlled trial (outcomes assessor).
- Trial name
- NCT02514148
- Testing
- Therapeutic patient education, Therapeutic exercise, No intervention
- Where
- Spain
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Madrid
Migraine
A Randomized, Placebo-Controlled, Double-blind Study of Tianshu Capsule in the Treatment of Migraine.
The purpose of this study is to evaluate the safety and the efficacy of Tianshu capsule treating Migraine Headache.
- Trial name
- NCT02035111
- Testing
- Tianshu capsule, Sugar pill
- Where
- 20 sites in China
- Volunteers
- 947 people
- Sponsor
- Jiangsu Kanion Pharmaceutical Co., Ltd
Migraine Headache
Examining the Efficacy of Kiko Exercises on the Prevention of Migraine Headaches
This pilot study hopes to show that after 3 months of Kiko training, Kiko naive patients with migraine will have a decrease in the frequency and severity of their migraines.
- Trial name
- NCT03651583
- Testing
- Kiko exercises-combines breathing and movement
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Regional Clinical Research
Migraine
Cervical Stability and Body Awareness in Migraine
The aim of this study is to compare cervical spinal stability, cervical proprioception, and body awareness in individuals with migraine and healthy controls, and to examine the relationship between these parameters.
- Trial name
- NCT07116590
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Hacettepe University
Migraine Disorders
Efficacy and Safety Study of BOTOX® Compared to Topiramate for the Prevention of Chronic Migraine in Adults
This study will evaluate the efficacy, safety and tolerability of prophylactic (preventative) treatment with BOTOX® (onabotulinumtoxinA) compared to topiramate in adults with chronic migraine.
- Trial name
- NCT02191579
- Testing
- onabotulinumtoxinA, Topiramate
- Where
- 32 sites in United States
- Volunteers
- 282 people
- Sponsor
- Allergan
Migraine
A Prospective Post-marketing Observational Study Assessing the Safety and Efficacy of Nerivio for Migraine Prevention.
Nerivio is a remote electrical neuromodulation (REN) device that is FDA-cleared for migraine prevention (as well as for acute treatment of migraine), in individuals 12 and older.
- Trial name
- NCT05940870
- Testing
- Nerivio
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Theranica
Chronic Migraine
Calcitonin Gene-related Peptide Levels in Chronic Migraine
Twenty patients will be enrolled in a 2-site, 7-month, double-blind study conducted to evaluate a reduction in headache days and attacks and calcitonin gene-related peptide (CGRP) levels in saliva following treatment with…
- Trial name
- NCT01071096
- Testing
- OnabotulinumtoxinA, Saline
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Cady, Roger, M.D.
Headache, Migraine
EP4-receptor Antagonism and Prostaglandin E2 (PGE2) in a Human Headache Model
The purpose of this study is to determine whether EP-4 receptor antagonist can prevent the headache expected during a Prostaglandin E2 infusion.
- Trial name
- NCT00957983
- Testing
- BGC20-1531
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Migraine
RCT of IV Dexamethasone to Prevent Relapse in the Treatment of Migraine in a Paediatric ED
Background: Headaches is one of the most common complaints of children in the ED and the treatment of pediatric migraine is largely based on extrapolation data from adult studies, limited pediatric trials, clinical experience and…
- Trial name
- NCT02903680
- Testing
- Dexamethasone group
- Where
- Canada
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
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