Clinical trials: Migraine, completed
Migraine Headache
Bioavailability of DHE Administered by I123 POD Device, IV Injection, and Migranal Nasal Spray in Healthy Adults
A Phase I clinical trial to compare the bioavailability of dihydroergotamine mesylate (DHE) following a single dose administration of INP104 (DHE administered by I123 Precision Olfactory Delivery (POD) Device Nasal Spray) to that…
- Trial name
- NCT03401346
- Testing
- INP104, Dihydroergotamine Mesylate (DHE), Migranal Nasal Spray
- Where
- Australia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Impel Pharmaceuticals
Migraine
Combined Occipital and Supraorbital Transcutaneous Nerve Stimulation for Treatment of Migraine
This study will evaluate the clinical performance and safety of a self administered abortive treatment for migraine headache using combined occipital and supraorbital transcutaneous nerve stimulator (Neurolief device, Relievion™).
- Trial name
- NCT03398668
- Testing
- Relievion device- Treatment stimulation
- Where
- Israel
- Volunteers
- 55 people
- Sponsor
- Neurolief Ltd.
Migraine
Clopidogrel For the Prevention of New Onset Migraine Headache Following Transcatheter Closure of Atrial Septal Defects
The addition of clopidogrel on top of aspirin may reduce the occurrence of new-onset migraine headache episodes following transcatheter ASD closure.
- Trial name
- CANOA (NCT00799045)
- Testing
- Clopidogrel
- Where
- Canada
- Volunteers
- 220 people
- Sponsor
- Laval University
Rapidly Escalating Migraine
Pilot Study of Two Different Strengths of DFN-11 Injection for Rapidly Escalating Migraine
Pilot study to compare the efficacy and safety of two strengths of injections of subcutaneous DFN-11 in subjects with rapidly escalating migraine headaches.
- Trial name
- NCT02571049
- Testing
- DFN-11
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Migraines
A Study of LY2951742 in Healthy Volunteers
To evaluate the safety and tolerability of LY2951742 given as single or multiple subcutaneous injection in healthy male subjects
- Trial name
- NCT01337596
- Testing
- LY2951742
- Where
- Belgium
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Migraine
Effectiveness and Neural Mechanism of Naoan Dripping Pills for Migraine
This is a randomized, double-blind, placebo-controlled clinical trial. Its main purpose is to investigate the effects and neural mechanism of Naoan dripping pills on migraine patients by utilizing fMRI and DTI method, as well as…
- Trial name
- ENMNM (NCT03175900)
- Testing
- Naoan dripping pills
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Dongzhimen Hospital, Beijing
Migraine Without Aura Prophylaxis
Dysport® In Migraine Without Aura Prophylaxis : DIMWAP Study
The purpose of this study is to determine whether 120 Unit, and 240 unit of botulinum toxin A are effective in the treatment of migraine without aura prophylaxis.
- Trial name
- NCT00258609
- Testing
- Botulinum Toxin type A (Dysport ® ) IM/SC 6-sites pericranial injection
- Where
- 6 sites in Thailand
- Volunteers
- 128 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Asthma, Allergic Rhinitis
Evaluation of an Integrated Care Project
The purpose of the study is to investigate the effectiveness and cost-effectiveness of the integrated care program of a statutory health insurance offering additional homeopathic treatment to their members
- Conditions
- Asthma, Allergic Rhinitis, Atopic Eczema, Migraine
- Trial name
- ediva (NCT01854580)
- Where
- Germany
- Volunteers
- 3,960 people
- Sponsor
- Charite University, Berlin, Germany
Headache, Migraine
The Effect of PACAP27 on the Extra- and Intracerebral Arteries Assessed by Magnetic Resonance Angiography (MRA) on Healthy Volunteers
Studying Pituitary adenylate cyclase-activating peptide 27 (PACAP27) effects on extra- and intracerebral arteries assessed by MRA on healthy volunteers.
- Trial name
- NCT03560024
- Testing
- PACAP27
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Migraine
BrainCool-Migraine Intranasal Cooling Trial
This study will be a randomised placebo controlled trial examining the effectiveness of using an intranasal evaporative cooling device (the RhinoChill intransal device) in providing relief of pain and symptoms of acute…
- Trial name
- NCT03167060
- Testing
- Active RhinoChill, Control Rhinochill
- Where
- 4 sites in United Kingdom
- Volunteers
- 90 people
- Sponsor
- Cumbria Partnership NHS Foundation Trust
Migraine, Tension-type Headache
Exercise in Migraine and Co-existing Tension-type Headache and Neck Pain
The purpose of this study is to study the effect of a physical exercise program on patients suffering from migraine and co-existing tension-type headache and neck pain.
- Conditions
- Migraine, Tension-type Headache, Neck Pain
- Trial name
- NCT02269501
- Testing
- Exercise treatment
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Danish Headache Center
Intractable Chronic Migraine
Peripheral Nerve Stimulation Registry for Intractable Migraine Headache
The purpose of this study is to evaluate the long-term safety and performance of neurostimulation for the treatment of intractable chronic migraine as well as to detect infrequent complications or problems only apparent in…
- Trial name
- Relief (NCT02227758)
- Where
- 18 sites in Belgium, Germany and 4 more
- Volunteers
- 112 people
- Sponsor
- Abbott Medical Devices
Migraine Without Aura
PACAP27 Headache Properties in Migraine Without Aura Patients
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a signaling molecule, localized in sensory and parasympathetic perivascular nerves fibres.
- Trial name
- NCT03471039
- Testing
- PACAP27, Saline
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Migraine
Ascending Single Doses of Erenumab (AMG 334) in Healthy Adults and Migraine Patients
The primary purpose of this study is to determine whether erenumab is safe and well tolerated in healthy adults and migraine patients.
- Trial name
- NCT01688739
- Testing
- Erenumab
- Where
- Belgium
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Amgen
Migraine
Ascending Multiple-Doses of Erenumab (AMG 334) in Healthy Adults and in Migraine Patients
The primary purpose of this study is to determine whether erenumab is safe and well tolerated in healthy adults and migraine patients.
- Trial name
- NCT01723514
- Testing
- Erenumab
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Amgen
Migraine With Aura, Migraine Without Aura
Is Chiropractic Spinal Manipulative Therapy an Efficient Treatment Option for Migraine
This study will highlight and validate chiropractic spinal manipulative therapy (CSMT) for migraine. If the method proves to be effective, it will provide a new non-pharmacological treatment option for migraine.
- Trial name
- NCT01741714
- Testing
- Chiropractic spinal manipulative therapy
- Where
- Norway
- Volunteers
- 104 people
- Sponsor
- University Hospital, Akershus
Migraine Disorders
BOTOX® Prophylaxis in Patients With Chronic Migraine
This is a post authorization observational study to monitor the utilization practices and describe the safety profile of BOTOX® in clinical practice for the prophylactic treatment of headaches in adult patients with chronic…
- Trial name
- NCT01432379
- Testing
- botulinum toxin Type A
- Where
- 4 sites in Germany, Spain and 2 more
- Volunteers
- 1,168 people
- Sponsor
- Allergan
Migraine
A Dose-Finding Study of MK-1602 in the Treatment of Acute Migraine (MK-1602-006)
The purpose of this study is to assess the effectiveness, safety and tolerability of a range of doses of MK-1602 versus placebo in the treatment of acute migraine.
- Trial name
- NCT01613248
- Testing
- MK-1602, Rescue medication
- Volunteers
- 834 people
- Sponsor
- Allergan
Migraine
Corticosteroids for Acute Migraine in the Emergency Department
This is an emergency department based randomized trial in which we compare two different treatment for migraine headache. The goal is to decrease the number of headache days during the week after ED discharge.
- Trial name
- NCT02847494
- Testing
- metoclopramide, Dexamethasone, methylprednisolone acetate
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- Montefiore Medical Center
Migraine, With or Without Aura
Efficacy, Safety, and Tolerability Study of Oral Ubrogepant in the Acute Treatment of Migraine
This study will evaluate the efficacy, safety, and tolerability of 2 doses of ubrogepant (50 and 100 mg) compared to placebo for the acute treatment of a single migraine attack.
- Trial name
- ACHIEVE I (NCT02828020)
- Testing
- Ubrogepant
- Where
- 90 sites in United States
- Volunteers
- 1,672 people
- Sponsor
- Allergan