Clinical trials: Migraine, completed
MIGRAINE
Efficacy of Manual Therapy in Migraine
Objective: The aim of this study was to determine the efficacy of suboccipital inhibitory manual therapy treatment in migraine compared to treatment based on Myofascial Trigger Points (MTrPs) and their stretching, often being…
- Trial name
- MTHDIQMi (NCT02446275)
- Testing
- Sternocleidomastoid MTRP and stretching, Trapezius MTRP and stretching
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Valencia
Migraine, Tension-type Headache
Exercise in Migraine and Co-existing Tension-type Headache and Neck Pain
The purpose of this study is to study the effect of a physical exercise program on patients suffering from migraine and co-existing tension-type headache and neck pain.
- Conditions
- Migraine, Tension-type Headache, Neck Pain
- Trial name
- NCT02269501
- Testing
- Exercise treatment
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Danish Headache Center
Migraine Disorders, Exercise
Educational Video Program to Promote Physical Activity and Reduce Migraine Frequency in Adults With Migraine
The goal of this clinical trial is to learn if an educational video program can help reduce migraine frequency and improve migraine-related outcomes in adults with migraine.
- Conditions
- Migraine Disorders, Exercise, Health Education, Audiovisual Aids
- Trial name
- PA-MIG (NCT06993545)
- Testing
- Video-based educational program on physical activity for migraine management
- Where
- Portugal
- Volunteers
- 307 people
- Sponsor
- Universidade do Porto
Migraine
Tampa Kinesiophobia Scale Modified for Headache
Tampa Kinesiophobia Scale is a scale that has been validated and reliable in individuals with low back pain in the Turkish population and evaluates fear of movement due to the risk of triggering pain.
- Trial name
- Kinesiophobia (NCT06857357)
- Testing
- Questionnaires
- Where
- 14 sites in Cyprus, Turkey (Türkiye)
- Volunteers
- 329 people
- Sponsor
- Bozok University
Migraine Without Aura
Amylin and CGRP Head to Head Provocation in Migraine Without Aura Patients
Amylin and calcitonin gene related peptide (CGRP) are related to the same peptide family. Both share 16 out of 37 amino acids and can activate each others receptor.
- Trial name
- NCT03598075
- Testing
- Amylin (Pramlintide), CGRP
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Migraine, Laughter
The Effect of Laughter Therapy in Women
Migraine: An episodic disorder consisting of severe headache, usually with photophobia (sensitivity to light), phonophobia (sensitivity to sound), and/or nausea (occasionally vomiting). Migraine is predominantly a female disease.
- Trial name
- NCT05804812
- Testing
- laughter therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Sinop University
Migraine
Effectiveness of Manual Lymphatic Drainage in the Physiotherapeutic Treatment of Migraine
Migraine is a highly prevalent neurological disorder associated with recurrent headache, disability, and reduced quality of life.
- Trial name
- EDLMMG (NCT07425041)
- Testing
- Manual lymphatic drainage
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Camilo Jose Cela University
Migraine, Medication Overuse Headache
Eptinezumab in Adults With Migraine and Medication Overuse Headache
This study evaluates the efficacy of eptinezumab to prevent migraine and headache in patients with the combined diagnosis of migraine and medication overuse headache
- Trial name
- Sunlight (NCT04772742)
- Testing
- Eptinezumab
- Where
- 40 sites in China, Georgia and 3 more
- Volunteers
- 193 people
- Sponsor
- H. Lundbeck A/S
Migraine, Sinusitis
Evaluation of Histamine, CGRP and VIP as Markers for Activation of Trigeminal and Parasympathetic Nerve Fibers
The primary objective of this study is to evaluate histamine, CGRP and VIP levels in saliva as biological markers for activation of trigeminal and parasympathetic nerve fibers in various clinical presentations of primary…
- Trial name
- NCT00208065
- Testing
- almotriptan or pseudoephedrine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Clinvest
Migraine Headache
Repeat Dosing of Psilocybin in Migraine Headache
In seeking to understand the capacity for psilocybin to reduce migraine headache burden, this study will investigate single and repeated dosing of psilocybin up to two doses.
- Trial name
- NCT04218539
- Testing
- Psilocybin
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Yale University
Migraine, Patent Foramen Ovale
Patent Foramen Ovale Closure in Migraine
The goal of this observational study is to retrospectively observe the effect of PFO closure and medication on migraine. The main questions it aims to answer are: Whether PFO closure is more effective in the treatment of migraine…
- Trial name
- NCT06192173
- Testing
- Percutaneous PFO closure
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Haiyan Wang
Migraine Disorders
A Study of Home-Delivered Neurostimulation for Migraine
There is a need for better preventive and abortive therapies for migraine. Previous research has indicated that non-invasive neurostimulation may have prophylactic effects on migraine and improve symptoms and functional outcomes…
- Trial name
- NCT03874351
- Testing
- non-invasive transcranial direct current stimulation (tDCS)
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- MJHS Institute for Innovation in Palliative Care
Migraine, Nocebo Effects
Default Mode Network Connectivity and Nocebo Responses in Migraine: A Functional MRI Study
People with migraine sometimes experience symptoms because they expect a treatment to cause side effects. This is known as the "nocebo effect".
- Trial name
- Does not exist (NCT07720895)
- Testing
- intravenous saline infusion, Negative verbal suggestion, No intervention
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Ioanna Spanou
Migraine, Medication Overuse Headache
A Study of Eptinezumab in Participants With Migraine and Medication Overuse Headache
Medication overuse headache (MOH) is a type of headache caused by excessive use of acute headache or migraine medications (medications used to treat a headache or migraine once it begins).
- Trial name
- RESOLUTION (NCT05452239)
- Testing
- Eptinezumab
- Where
- 76 sites in United States, Australia and 9 more
- Volunteers
- 608 people
- Sponsor
- H. Lundbeck A/S
Migraine
The Evaluation of Pharmacokinetic/Pharmacodynamic Characteristics and Safety of QDX in Healthy Korean Male Subjects
To evaluate pharmacokinetic/pharmacodynamic characteristics and safety of QDX after single oral administration in healthy Korean male subjects
- Trial name
- NCT04401137
- Testing
- Topiramate
- Where
- South Korea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- SK Chemicals Co., Ltd.
Nutrition Disorders, Migraine Disorders
Dietary Advanced Glycation End Products and Migraine
Is dietary intake of advanced glycation different between individuals with and without migraine? Is there a difference between the groups in terms of energy and nutrients? The answers to these questions are sought.
- Trial name
- NCT05747911
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Migraine
The Effectiveness of Almotriptan Malate (AXERT®) 12.5 Milligrams When Taken at the Onset of Migraine Pain
The purpose of this study is to evaluate the effectiveness and safety of AXERT when treating a migraine at the onset of headache pain, as compared to treating a migraine only after the headache pain has reached at least moderate…
- Trial name
- NCT00212823
- Testing
- almotriptan malate
- Volunteers
- 1,450 people
- Sponsor
- Ortho-McNeil Neurologics, Inc.
Migraine, Headache
The Hemodynamic Effects of PACAP38 After Glibenclamide Administration in Healthy Volunteers
To investigate the hemodynamic effects of PACAP38 after glibenclamide administration.
- Conditions
- Migraine, Headache, Pain
- Trial name
- NCT04960657
- Testing
- glibenclamide, PACAP38
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Migraine Disorders
Sofusa System With Sumatriptan (KC5010) Phase 1 Dose Escalation Safety and PK Study (KCC-SMT-002)
Study KCC-SMT-002, is a Phase 1, single-site, open-label, non-randomized, crossover, flexible dose design study to investigate the pharmacokinetic (PK) and safety comparing the Sofusa™ system with sumatriptan (KC5010) to Imitrex®…
- Trial name
- KCC-SMT-002 (NCT03229798)
- Testing
- Sumatriptan Succinate Oral Tablet, Transdermal delivery of sumatriptan succinate
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Sorrento Therapeutics, Inc.
Migraine, Greater Occipital Nerve Pulsed Radiofrequency, Headache Disorders
Comparing Unilateral and Bilateral Proximal GONPRF in Migraine Treatment
This study is designed to compare the clinical effectiveness of unilateral and bilateral Greater Occipital Nerve Pulsed Radiofrequency (GON-PRF) treatment at the C2 level in patients with migraine.
- Conditions
- Migraine, Greater Occipital Nerve Pulsed Radiofrequency, Headache Disorders, Ultrasound Guided Nerve Block
- Trial name
- (UBGON-PRF) (NCT06894121)
- Testing
- Greater Occipital Nerve Pulsed Radiofrequency (Unilateral), Bilateral GON PRF Treatment:
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people
- Sponsor
- Ankara City Hospital Bilkent
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