Clinical trials: Migraine Prophylaxis
Migraine
Medicinal vs. Orthotic Comparison for Migraine Prevention: A Double-Blind Study
To understand the impacts of using a fixed orthotic facial exercise appliance (BLAfit®) for migraine reduction, as compared to medication (fremanezumab-vfrm) and control.
- Trial name
- NCT04547179
- Testing
- Fremanezumab-Vfrm, BLAfit®, Saline
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Manhattan Beach Orthodontics
Migraine, Omega-3 Polyunsaturated Fatty Acids
Omega-3 Fatty Acid in the Prevention of Migraine
To understand the clinical efficacy for omega-3 PUFAs migraine prevention.To uncover the underlying biochemical or neurophysiological mechanisms by which omega-3 PUFAs for migraine prevention.
- Trial name
- NCT04572789
- Testing
- Omega-3 polyunsaturated fatty acids, omega-6 PUFAs
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kuang Tien General Hospital
Migraine
Topical Intra-Oral Ketoprofen for Migraine Prevention
Intra-Oral Topical Ketoprofen gel, applied to a branch of the trigeminal nerve, has been shown to prevent migraines when used once daily for 3 months in open label studies.
- Trial name
- NCT01211795
- Testing
- topical intraoral ketoprofen gel
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Behar, Caren, M.D.
Migraine
Prospective Survey of Menstrual Migraine & Prevention With Eletriptan
Women are followed prospectively for 3 months, recording headaches, other symptoms, and menstrual periods. Those with menstrual migraine are treated perimenstrually with eletriptan for 3 months.
- Trial name
- NCT00259649
- Testing
- eletriptan
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Migraine Without Aura, Unilateral Headache
Acupuncture for Migraine Prophylaxis
Hypothesis: Acupuncture obtains an abiding effect on migraine prophylaxis Design: A open-label randomized controlled trial. 249 participants will be included.
- Trial name
- AMP (NCT01687660)
- Testing
- acupuncture
- Where
- China
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Li ying
Migraine
Safety and Efficacy of Oral Idebenone for Preventive Treatment of Migraine in Adult Migraine Patients
This is a multi-center, prospective, double-blind randomized controlled trial on a sample of patients with migraine. Subjects will only be enrolled when a physician or research assistant who is familiar with the study protocol is…
- Trial name
- NCT05411978
- Testing
- Idebenone
- Where
- China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Headache, Migraine
Headache and Hormone Use Among Transgender Population in Thailand: A Cross-Sectional Online Study
The goal of this observational study is to learn how common headache and migraine are and to describe headache patterns among transgender adults in Thailand.
- Trial name
- H-TRANS (NCT07817446)
- Testing
- gender-affirming hormone therapy, Gender-Affirming Surgery, HIV Pre-Exposure Prophylaxis
- Where
- Thailand
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Chronic Migraine
NINDS CRC Chronic Migraine Treatment Trial
The purpose of this study is to compare the reduction in the number of severe headache days at six months in people with chronic migraine treated with topiramate and propranolol versus those treated with topiramate and a placebo.
- Trial name
- CMTT (NCT00772031)
- Testing
- propranolol LA, topiramate
- Where
- 39 sites in United States
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- Anne Lindblad
Migraine, Headache
Acupuncture as Migraine Prophylaxis in Reducing Frequency, Duration and Intensity of Migraine With Minimum Acupoint, Seen up to Eight Weeks From Baseline
Migraine is a primary headache attack, specific, paroxysmal, with or without aura, with subjective manifestations both before and after the attack, a chronic type of headache with symptoms of recurrence, attacks at productive age…
- Conditions
- Migraine, Headache, Migraine Disorders
- Trial name
- NCT04509141
- Testing
- acupuncture
- Where
- Indonesia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Migraines, Bleeding
Prevention of Menstrual Migraines: Using Frovatriptan or Placebo During Hormone Free Intervals
This study will examine the combined effects of a continuous oral contraceptive (OC) regimen with supplemental frovatriptan therapy on headache severity and occurrence in subjects with documented Menstrually Associated Migraines…
- Conditions
- Migraines, Bleeding, Spotting
- Trial name
- MAM (NCT00700128)
- Testing
- frovatriptan
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Scott and White Hospital & Clinic