Clinical trials: Migraine With Aura
Migraine, Migraine Without Aura
Efficacy of CLORazepate for the Treatment of MIGraine Attack in the Emergency Room
The purpose of this study is to evaluate the efficacy of clorazepate in addition to the usual medication for treating migraine attack in the emergency room
- Conditions
- Migraine, Migraine Without Aura, Migraine With Aura, Headache
- Trial name
- CLORMIG (NCT04726592)
- Testing
- Clorazepate Dipotassium, Ketoprofen, Metoclopramide
- Where
- France
- Volunteers
- 323 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Migraine Disorders, Migraine, Classic
Understanding the Pathophysiology of Migraine Pain
Migraine is the most common headache disorder, prevalent in 18% of females and 6% of males. Emergency room visits, physician consults, hospitalizations, medications, and indirect costs such as lost work days and decreased…
- Conditions
- Migraine Disorders, Migraine, Classic, Migraine Without Aura
- Trial name
- NCT03026101
- Testing
- Nitroglycerin
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Montefiore Medical Center
Migraine With Aura, Migraine Without Aura
Migraine With and Without Aura Characteristics and Response to Remote Electrical Neuromodulation (REN) Treatment
This is a Post-marketing, real-world evidence study investigating the safety and efficacy of the acute treatment of migraine with a Remote Electrical Neuromodulation (REN) device (Nerivio) in migraine patients with and without…
- Trial name
- NCT06023953
- Testing
- Nerivio device
- Where
- Israel
- Volunteers
- 31,715 people
- Sponsor
- Theranica
Migraine Aura, Migraine With Aura
Induction of Migraine Attacks With Aura Using Calcitonin Gene-Related Peptide
Calcitonin gene-related peptide (CGRP) is a key neuropeptide in migraine pathophysiology and treatment. This study investigates whether CGRP administration can trigger aura in individuals with a diagnosis of migraine with aura.
- Trial name
- NCT07021859
- Testing
- Calcitonin-gene related peptide (CGRP)
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Danish Headache Center
Migraine Without Aura
Efficacy and Mechanism of Fu's Subcutaneous Needling Treatment for Migraine Without Aura
This study aimed to compare the analgesic efficacy and quality-of-life improvement between FSN and flunarizine hydrochloride in patients with migraine without aura.
- Trial name
- NCT07068815
- Testing
- Fu's Subcutaneous Needling, Flunarizine Hydrochloride
- Volunteers
- 60 people
- Sponsor
- Guangzhou University of Chinese Medicine
Migraine, Migraine Disorders
Healthy Living Partnerships for Veterans With Migraine
This pilot study, modeled upon the successful and empirically validated HELP Prevent Diabetes Intervention, incorporates a migraine education component describing the links between lifestyle behaviors and migraine activity (e.g.…
- Conditions
- Migraine, Migraine Disorders, Migraine With Aura, Migraine Without Aura
- Trial name
- HELP-VM (NCT04373330)
- Testing
- Intensive Lifestyle Intervention
- Sponsor
- Wake Forest University Health Sciences
Migraine, Migraine Disease
Assessment of Oral Caffeine Intake in Changing the Severity of Acute Migraine Attack Using VAS Score Among Patients Attending Headache and Neurology Outpatients Clinic of Ainshams University Hospitals
Caffeine extracted from green tea to abort acute attack of Migraine
- Conditions
- Migraine, Migraine Disease, Migraine Headache, Migraine Headache, With or Without Aura
- Trial name
- NCT07022496
- Testing
- Caffeine (200 mg), triptans, NSAID (Nonsteroidal anti-inflammatory drugs)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Migraine With Aura, Migraine Without Aura
Evaluation of the Efficacy of Almotriptan and Ubrogepant for the Acute Treatment of Migraine
In a real-world population of adults with migraine, the investigators would like to investigate whether 12.5 mg almotriptan is non-inferior to 50 mg ubrogepant in terms of pain freedom at 2 hours after drug intake.
- Trial name
- ATOM (NCT05214001)
- Testing
- Almotriptan 12.5 Mg Oral Tablet, Ubrogepant 50Mg Tab
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- Messoud Ashina, MD
Migraine With Aura
PArtial REbreathing for Migraine With Aura 1
A prospective, multi-centre, randomized, double-blind, sham-controlled, parallel-group, group-sequential study to investigate safety and effectiveness of the Rehaler partial rebreathing device, in adults suffering from migraine…
- Trial name
- PAREMA1 (NCT05546385)
- Testing
- Partial Rebreathing Device
- Where
- 15 sites in United States, Germany
- Volunteers
- 142 people
- Sponsor
- Rehaler
Chronic Migraine, Chronic Migraine, Headache
A Study to Evaluate the Efficacy and Safety of TNX-1900 in Patients With Chronic Migraine
This is a phase 2, double-blind, randomized, multicenter, placebo-controlled, three arm parallel study to evaluate the efficacy and safety of two different dosages (30 IU daily and 60 IU daily) of TNX-1900 in patients with…
- Conditions
- Chronic Migraine, Chronic Migraine, Headache, Chronic Migraine Without Aura, Aura Migraine
- Trial name
- PREVENTION (NCT05679908)
- Testing
- TNX-1900
- Where
- 26 sites in United States
- Volunteers
- 88 people
- Sponsor
- Tonix Pharmaceuticals, Inc.
Migraine Without Aura, Headache
Effect of Sumatriptan on Levcromakalim-Induced Symptoms in Individuals With Migraine
The study aims to explore the effects of Sumatriptan on Levcromakalim-induced migraine in individuals with migraine without aura.
- Trial name
- SLIM (NCT05211050)
- Testing
- Levcromakalim, Sumatriptan, Saline
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Danish Headache Center
Headache (Migraine), Migraine
Molecular Phenotyping of Migraine Patients According to Sex and Age Through CGRP Quantification
Patients will be asked to visit the study center 2 times, the first time for clinical assessment and a second time for sample collection. Healthy controls will only be asked to visit the study center for sample collection.
- Conditions
- Headache (Migraine), Migraine, Migraine Headache, Migraine with Aura
- Trial name
- FAST (NCT06674772)
- Testing
- Saliva test
- Where
- Spain
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Episodic Migraine, Migraine With Aura
Mi-Helper Transnasal Cooling for Acute Treatment of Migraine
This is a prospective, double-blind, sham-controlled, randomized clinical trial . This study aims to assess the efficacy, safety, tolerability, and the optimal dose of the Mi-Helper transnasal cooling device for acute treatment…
- Conditions
- Episodic Migraine, Migraine With Aura, Migraine Without Aura, Migraine
- Trial name
- NCT06051604
- Testing
- Mi-Helper
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- CoolTech LLC
Migraine Without Aura, Migraine With Aura
TIzanidine for the Preventive Treatment of Episodic MigrainE （TIME）
In this study,189 adult migraine patients aged 18-65 years (diagnosed with migraine without aura and/or migraine with aura, with at least a 1-year history)will be collected to evaluate the efficacy, safety and tolerability of…
- Trial name
- NCT05484349
- Testing
- Tizanidine Hydrochloride
- Where
- 6 sites in China
- Volunteers
- 189 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Migraine Without Aura
Effect of Riocigaut on Migraine Attack Induction in People With Migraine
This double-blind, randomized, placebo-controlled cross-over clinical trial aims to investigate the effects of riocigaut on migraine inducing properties in people with migraine.
- Trial name
- NCT05750446
- Testing
- Riociguat (BAY 63-2521)
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- Danish Headache Center
Ischemic Stroke, Migraine
Sensitivity to Acute Cerebral Ischemia in Migrainers
Sensitivity to Acute Middle cerebral or intracranial Carotid artery Occlusion in MIGrainers (SMCO-MIG) is a prospective multi-center study to determine if migraine induces a faster infarct growth as assessed by initial multimodal…
- Conditions
- Ischemic Stroke, Migraine, Migraine With Aura
- Trial name
- SAMCO-MIG (NCT03301441)
- Testing
- questionnaire ef-ID Migraine
- Where
- France
- Volunteers
- 605 people
- Sponsor
- University Hospital, Montpellier
Acute Migraine With or Without Aura in Adolescents
A Study to Evaluate the Safety and Tolerability of Rizatriptan for Long Term Treatment of Acute Migraine in Children and Adolescents (MK-0462-086 AM3)
To provide long term safety data for rizatriptan in children and adolescents. The primary hypothesis of the study is that rizatriptan is well tolerated in the long term treatment of acute migraine in pediatric patients age 12-17…
- Trial name
- NCT01004263
- Testing
- rizatriptan benzoate
- Volunteers
- 674 people
- Sponsor
- Organon and Co
Platelet Aggregation, Spontaneous, Migraine With Aura
pLatelEts And MigRaine iN patEnt foRamen Ovale
Migraine is a common, chronic neurovascular disorder characterized by attacks of severe headache, autonomic nervous system dysfunction and, in some patients, aura, and disabling neurological symptoms.
- Conditions
- Platelet Aggregation, Spontaneous, Migraine With Aura, Patent Foramen Ovale
- Trial name
- LEARNER (NCT03521193)
- Testing
- patent foramen ovale closure
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Centro Cardiologico Monzino
Migraine With or Without Aura
The Preventive Treatment of Migraine With Low-Dose Naltrexone and Acetaminophen Combination
The Preventive Treatment of Migraine with Low-Dose Naltrexone and Acetaminophen Combination: A Small, Randomized, Double-Blind, and Placebo-Controlled Clinical Trial with an Open-Label Extension for None-Responders
- Trial name
- NCT03194555
- Testing
- Low-Dose Naltrexone and Acetaminophen Combination
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Allodynic Therapeutics, Inc
Migraine Without Aura, Migraine With Aura
Anisodine Hydrobromide For The Preventive Treatment Of Episodic Migraine
In this study,288 adult migraine patients aged 18-65 years (diagnosed with migraine without aura and/or migraine with aura, with at least a 1-year history)will be collected to evaluate the efficacy, safety and tolerability of…
- Trial name
- ATEM (NCT05416476)
- Testing
- Anisodine Hydrobromide
- Where
- 19 sites in China
- Volunteers
- 288 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine