Clinical trials: Migraine With and Without Aura
Tinnitus
Management of Acute Tinnitus With Migraine Medications
Tinnitus represents one of the most common and distressing otologic problems, and it causes various somatic and psychological disorders that interfere with the quality of life.
- Trial name
- NCT06799169
- Testing
- Nortriptyline, Topiramate, Paroxetine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Irvine
Migraine, Migraine Disease
A Prospective, Open-Label Study Evaluating the Effectiveness of Gepants for Acute Treatment of Migraine in the Emergency Department
Prospective, single-site, open-label, non-controlled pilot study consisting of two parallel trials. Participants will receive rimegepant or zavegepant for acute migraine treatment during a single Emergency Department visit, with…
- Conditions
- Migraine, Migraine Disease, Migraine in Adults, Migraine Headache
- Trial name
- NCT07667621
- Testing
- Rimegepant, Zavegepant
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Migraine, With or Without Aura
Efficacy and Safety of BR005-036C Tablets for the Acute Treatment of Migraine in Adults
The purpose of this study is to compare the efficacy and safety of BR005-036C versus placebo in subjects with Acute Migraines
- Trial name
- NCT07792681
- Testing
- BR005-036C
- Where
- 83 sites in China
- Volunteers
- 2,079 people
- Sponsor
- Brise Pharmaceuticals Co., Ltd.
Migraine
Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study
This goal of this study is to compare three medications used for migraine preventive treatment. This study will compare atogepant, a newer migraine preventive medication, with two older preventive medications, topiramate and…
- Trial name
- NCT06972056
- Testing
- Atogepant 60 mg, Propranolol 160 mg, Topiramate 100 mg
- Where
- 37 sites in United States
- Volunteers
- 1,335 people
- Sponsor
- Mayo Clinic
Migraine
Study of EVO756 in Adults With Migraine
This study will evaluate the efficacy and safety of EVO756 against placebo in adults with migraine.
- Trial name
- NCT07616128
- Testing
- EVO756, Dose 1, EVO756, Dose 2
- Where
- 35 sites in United States, Canada and 1 more
- Volunteers
- 330 people
- Sponsor
- Evommune, Inc.
Migraine Disorders, Migraine With Aura
Using Virtual Reality to Teach Mindfulness to People With Migraine
The aim of this clinical trial is to learn if people with migraine can learn a type of biobehavioral therapy called Acceptance and Commitment Therapy (ACT) by using a virtual reality headset.
- Conditions
- Migraine Disorders, Migraine With Aura, Migraine Without Aura, Episodic Migraine
- Trial name
- MIRAGE (NCT07599228)
- Testing
- ACT therapy delivered by REACT NeuroVR headset
- Where
- 3 sites in United States
- Volunteers
- 160 people
- Sponsor
- Brigham and Women's Hospital
Migraine With or Without Aura
A Study to Learn About the Study Medicine NURTEC® ODT 75 mg After it is Released Into the Markets in Korea
The purpose of this study is to evaluate safety and effectiveness of NURTEC® ODT 75 mg (Rimegepant sulfate) in adult patients with acute treatment of migraine with or without aura and with preventive treatment of episodic…
- Trial name
- Rimegepant PMS (NCT07497854)
- Testing
- Rimegepant sulfate
- Volunteers
- 3,000 people
- Sponsor
- Pfizer
Migraine, With or Without Aura
Long-term Safety of BR005-036C Tablets in the Acute Treatment of Migraine in Adults
The purpose of this study is to evaluate the long-term safety of BR005-036C tablets in the acute treatment of migraines
- Trial name
- NCT07835152
- Testing
- BR005-036C
- Where
- 81 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Brise Pharmaceuticals Co., Ltd.
Migraine, Migraine Headache
Migraine Attack Pain Phase Prediction Study
The study of the ability to predict pain in a migraine attack, through premonitory symptoms and through an ambulatory monitoring device through real-time recording of hemodynamic variables, is one of the strategic lines of…
- Conditions
- Migraine, Migraine Headache, Migraine Disorders, Migraine Without Aura
- Trial name
- PREDI-CRISIS (NCT06459635)
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Cluster Headache - Episodic and Chronic, Migraine Headache
Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEAD - a Pilot Study
Migraine and/or Cluster Headache: Study Overview Background: Migraine and cluster headache are two primary headache disorders that significantly impact quality of life and functionality in those affected.
- Conditions
- Cluster Headache - Episodic and Chronic, Migraine Headache, Migraine Headache, With or Without Aura, Migraine in Adults
- Trial name
- NCT07292090
- Testing
- Intervention yogabased movements
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Karolinska Institutet
Cluster Headache - Episodic and Chronic, Migraine Headache
Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEAD
Brief Summary: Migraine and/or Cluster Headache: Study Overview Background: Migraine and cluster headache are two primary headache disorders that significantly impact quality of life and functionality in those affected.
- Conditions
- Cluster Headache - Episodic and Chronic, Migraine Headache, Migraine Headache, With or Without Aura, Migraine in Adults
- Trial name
- NCT07348783
- Testing
- Intervention yoga based exercises
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska Institutet
Headache, Headache Disorders
Mind Body Balance for Pediatric Migraine
This study uses a factorial research design to evaluate a nurse delivered mind body intervention using different doses of 3 treatment components to determine the optimized treatment for headache day reduction.
- Conditions
- Headache, Headache Disorders, Headache, Migraine, Migraine
- Trial name
- NCT04715685
- Testing
- 40 minute session, 20 minute session, home practice e-health
- Where
- 2 sites in United States
- Volunteers
- 260 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Headache, Headache Disorders
Responding With Evidence and Access for Childhood Headaches
This comparative effectiveness study will clarify current first-line preventive treatment approaches for use by neurologists, psychologists, and primary care providers in the context of real world care, and will demonstrate the…
- Conditions
- Headache, Headache Disorders, Headache, Migraine, Migraine
- Trial name
- NCT05889624
- Testing
- CBT, Amitriptyline
- Where
- 15 sites in United States
- Volunteers
- 400 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Migraine, Migraine With Aura
A Comprehensive Digital Care Program for Migraine Management
This study evaluates the clinical effectiveness of the Enso for Migraine program, a comprehensive digital care program combining an FDA-cleared neuromodulation wearable device (Enso), personalized exercise therapy, and a…
- Conditions
- Migraine, Migraine With Aura, Migraine Without Aura
- Trial name
- NCT07642414
- Testing
- Neuromodulation Wearable Device, Migraine Digital Care Program
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Hinge Health, Inc
Migraine Disorders
Preventive Role of Melatonin and Propranolol Administration in Pediatric Migraine
This randomized controlled trial evaluated whether adding melatonin to propranolol provided better prevention of migraine in children than propranolol alone.
- Trial name
- NCT07743255
- Testing
- Melatonin, Propranolol
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Nishtar Medical University
Migraine, Migraine With or Without Aura
Exploring the Effect of the Transcendental Meditation® Technique on Migraine Frequency, Intensity, and Functionality: A Single-Arm Study
This research will explore the effect of the Transcendental Meditation® Technique on migraine intensity and frequency. It will be a single-arm pilot study involving 30 participants recruited from migraine treatment facilities and…
- Trial name
- NCT06695156
- Testing
- Meditation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Maharishi International University
Migraine Without Aura, Acupuncture Therapy
Brain Connectome for Acupuncture-treated Migraine Patients
Acupuncture has been a means of treating headaches and migraine since 2002 and is now a World Health Organisation-recognized prophylactic treatment for migraine.
- Trial name
- ACU-BRAIN (NCT04157192)
- Testing
- Real acupuncture
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Migraine
BE WELL With Migraine: Brain Education and WELLness With Migraine
The goal of this randomized clinical trial is to evaluate two different non-drug, virtual treatment options designed to improve the lives of patients with migraine.
- Trial name
- NCT05987592
- Testing
- Brain Education and WELLness with Migraine Group A, Brain Education and WELLness with Migraine Group B
- Where
- 3 sites in United States
- Volunteers
- 286 people
- Sponsor
- Wake Forest University Health Sciences
Migraine, Migraine With Aura
RimegepAnt effectIvenesS and tolErability as Migraine Preventive Treatment
The purpose of this prospective and multicentric study is to evaluate the effectiveness and tolerability of rimegepant as preventive migraine treatment in a cohort of episodic or chronic migraine patients.
- Conditions
- Migraine, Migraine With Aura, Migraine Without Aura
- Trial name
- RAISE (NCT06409832)
- Testing
- Rimegepant 75 mg
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University of Florence
Migraine, Migraine With Aura
Effectiveness and Tolerability of Eptinezumab
The purpose of this prospective and multicentric study is to evaluate the effectiveness and tolerability of eptinezumab as preventive migraine treatment in a cohort of episodic or chronic migraine patients.
- Conditions
- Migraine, Migraine With Aura, Migraine Without Aura, Chronic Migraine
- Trial name
- TACHIS (NCT06409845)
- Testing
- Eptinezumab 100 or 300 mg ev
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- University of Florence