Clinical trials: Migraine in Children
Migraine
RCT of IV Dexamethasone to Prevent Relapse in the Treatment of Migraine in a Paediatric ED
Background: Headaches is one of the most common complaints of children in the ED and the treatment of pediatric migraine is largely based on extrapolation data from adult studies, limited pediatric trials, clinical experience and…
- Trial name
- NCT02903680
- Testing
- Dexamethasone group
- Where
- Canada
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Migraine
AMG 334 20160172 Pediatric Migraine PK Study.
AMG 334 20160172 Pediatric Migraine PK Study.
- Trial name
- NCT03499119
- Testing
- AMG 334 Dose 1, AMG 334 Dose 2, AMG 334 Dose 3
- Where
- 14 sites in United States
- Volunteers
- 53 people
- Sponsor
- Amgen
Migraine in Children
A Survey Study to Assess the Accessibility of the Nerivio Device At School
This is a retrospective survey-study to assess the accessibility, preference, and frequency of adolescents using Nerivio by itself, in combination with pharmacological medications, or not at all, in the school setting.
- Trial name
- NCT06180577
- Testing
- Nerivio
- Where
- United States
- Volunteers
- 332 people
- Sponsor
- Theranica
Migraine Disorders, Headache Disorders
Therapy for Migraine Prevention in Children 6-11 Years of Age
The aim of this study is to evaluate the effect of SPN-538 for the prophylaxis of migraine in pediatric patients 6 to 11 years old.
- Trial name
- NCT04050293
- Testing
- SPN-538
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
Migraine, Acute
A Study to Evaluate the Efficacy and Tolerability of Rizatriptan for Treatment of Acute Migraine in Children and Adolescents (MK-0462-082 AM7)
This Clinical Trial evaluates the Safety and Efficacy of Rizatriptan for the Acute Treatment of Migraine in Children and Adolescents.
- Trial name
- NCT01001234
- Testing
- rizatriptan
- Volunteers
- 1,382 people
- Sponsor
- Organon and Co
Irritable Bowel Syndrome (IBS), Functional Abdominal Pain
Peer Mentorship: An Intervention To Promote Effective Pain Self-Management In Adolescents
This protocol matches child subjects with peer mentors of similar age who have learned to function successfully with a chronic pain disorder.
- Conditions
- Irritable Bowel Syndrome (IBS), Functional Abdominal Pain, Fibromyalgia, Complex Regional Pain Syndrome (CRPS)
- Trial name
- NCT01118988
- Testing
- Mentorship
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of California, Los Angeles
Acute Treatment of Migraine
Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine
The purpose of this study is to test the long-term safety of rimegepant in the acute treatment of migraine in children and adolescents (≥ 6 to < 18 years of age).
- Trial name
- NCT04743141
- Testing
- Rimegepant (PF-07899801)
- Where
- 124 sites in United States, Poland and 1 more
- Volunteers
- 600 people
- Sponsor
- Pfizer
Migraine, Headache
Intravenous Fluid for Pediatric Migraine in the Emergency Department
The purpose of this study is to evaluate the effect of intravenous fluid (0.9% sodium chloride and water) alone on headache pain in children with migraine visiting the Emergency Department.
- Trial name
- EDMigraine3 (NCT01073787)
- Testing
- Normal saline
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- University of Alberta
Migraine in Children, Pain, Neuropathic
Transnasal Sphenopalatine Ganglia Block for Management of Chronic Migraines in Pediatric Patients
Single-center, open-label, pre-post treatment pilot study to evaluate the safety and effectiveness of sphenopalatine ganglia blocks for the treatment of chronic migraine in the pediatric population.
- Trial name
- NCT04466826
- Testing
- Headache Journal, Sphenopalatine Block, Tx360
- Where
- United States
- Sponsor
- Washington University School of Medicine
Chronic Migraine in Children
A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine
To find out if eptinezumab is better than placebo (normal saline solution) in lowering the number of days with migraine in young people ages 12 to 17 with chronic migraine.
- Trial name
- PROSPECT-2 (NCT04965675)
- Testing
- Eptinezumab
- Where
- 79 sites in United States, Argentina and 9 more
- Volunteers
- 285 people
- Sponsor
- H. Lundbeck A/S
Headache Disorders, Migraine Disorders
Intervention for Sleep and Pain in Youth
This study tests the feasibility, acceptability, and preliminary efficacy of a seven-session cognitive-behavioral therapy intervention to treat sleep and pain problems in youth ages 11-17 with co-morbid headache and insomnia.
- Conditions
- Headache Disorders, Migraine Disorders, Insomnia
- Trial name
- I-SPY (NCT03137147)
- Testing
- Intervention for Sleep and Pain in Youth
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Seattle Children's Hospital
Vestibular Migraine
Non-Pharmacological Treatment of Vestibular Migraine in Children and Adolescent
Vestibular dysfunction has traditionally been linked to various conditions that affect older adults. Recent studies have shown that children and adolescents suffer from vestibular impairments, yet the numbers are still low due to…
- Trial name
- NCT05914207
- Testing
- Lifestyle modifications, Vestibular rehabilitation exercise
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- University of Malaya
Migraine, Migraine Disorders
The Childhood and Adolescent Migraine Prevention Study
The purpose of this research study is to test two medicines for migraine prevention in children and adolescents.
- Conditions
- Migraine, Migraine Disorders, Headache
- Trial name
- CHAMP (NCT01581281)
- Testing
- Amitriptyline, Topiramate
- Where
- 35 sites in United States
- Volunteers
- 488 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Functional Abdominal Pain Disorders, Irritable Bowel Syndrome (IBS)
VICO-trial: Video Consultations in the Follow-up of Children With Functional Abdominal Pain Disorders
The goal of this non-inferiority randomized controlled multi-center trial is to investigate the use of video consultations in the follow-up care of children aged 4 - 18 years old with functional abdominal pain disorders (FAPDs).
- Conditions
- Functional Abdominal Pain Disorders, Irritable Bowel Syndrome (IBS), Functional Dyspepsia, Abdominal Migraine
- Trial name
- VICO (NCT06665867)
- Testing
- Video consultation, Face-to-face consultation
- Where
- Netherlands
- Volunteers
- 208 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Chronic Migraine
Cannabis for Chronic Headaches in Adolescents: the CAN-CHA Trial
Chronic headaches are a major cause of disability among adolescents. Cannabis products have supported the management of headaches in adults and may play a role in pediatric chronic pain.
- Trial name
- CAN-CHA (NCT05337033)
- Testing
- MPL-001
- Where
- 3 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Pediatric Migraine
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
The purpose of this study is to test the safety and efficacy of BHV-3000 versus placebo in the acute treatment of moderate or severe migraine in children and adolescents.
- Trial name
- NCT04649242
- Testing
- Rimegepant/BHV3000
- Where
- 246 sites in United States, Canada and 7 more
- Volunteers
- 2,100 people
- Sponsor
- Pfizer
Migraine, Migraine in Children
Intravenous Fluids in Pediatric Migraine
The goal of this clinical trial is to compare intravenous (IV) fluids in pediatric patients with migraine. The main questions it aims to answer are: Does a large amount of fluids (bolus) improve pain Does a large amount of fluids…
- Trial name
- NCT06182098
- Testing
- 1/2 maintenance fluids, Ketorolac, Diphenhydramine
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Dayton Children's Hospital
Primary Headaches (Includes Migraines, Tension, Cluster Headaches), Hydration
Hydration in Children and Adolescents With Primary Headaches
The aim of this study is to investigate the role of hydration and fluid intake in children and adolescents with primary headaches.
- Conditions
- Primary Headaches (Includes Migraines, Tension, Cluster Headaches), Hydration, Adolescent, Children
- Trial name
- H20KIDS (NCT06816849)
- Testing
- Recommended water intake
- Where
- Slovenia
- Volunteers
- 60 people
- Sponsor
- University Medical Centre Ljubljana
Primary Headache Disorder
Feasibility of a Developmentally-tailored Mobile App for Tracking Mood and Pain in Children With Migraine
This study aims to inform the continued development of a mobile app intended to support the treatment of CYP with migraine. After extensive public and patient involvement, Happyr Health has developed a mobile app that allows…
- Trial name
- NCT05337930
- Testing
- Happyr App
- Where
- United Kingdom
- Sponsor
- Happyr Ltd