Clinical trials: Mild Obstructive Sleep Apnea
Obstructive Sleep Apnea
The Effect of Pure Prone Positioning Therapy for the Patients With Mild to Moderate Obstructive Sleep Apnea
Efficacy of Pure Prone Positioning (PPP) treatment in improving apnea-hypopnea index (AHI) and nocturnal oxygen saturation was investigated in mild to moderate Obstructive Sleep Apnea.
- Trial name
- NCT01368952
- Testing
- Pure prone positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital
Obstructive Sleep Apnea of Adult, Myofunctional Therapy
Myofunctional Therapy in Patients With Mild-moderate Sleep Apnea
The main objective of this study is to compare the change in the apnea-hypopnea index (AHI) in patients with mild to moderate sleep apnea without daytime sleepiness after 12 months of myofunctional therapy exercises with respect…
- Trial name
- NCT04169984
- Testing
- Myofunctional Therapy
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Obstructive Sleep Apnea
Nasal Budesonide in Children With Rhinitis and/or Mild Obstructive Sleep Apnea Syndrome
-Intranasal budesonide therapy may lead to improved symptoms and sleep study findings in children with mild obstructive sleep apnea with and without allergic rhinitis that would not be treated with T\&A.
- Trial name
- NCT00560586
- Testing
- Budesonide
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Louisville
Snoring, Obstructive Sleep Apnea
Safety, and Tolerability of the ZENS Device (PLUTO)
The primary objective of the PLUTO study is to evaluate the safety and tolerability of the ZENS transcutaneous nerve stimulator device in primary snorers and those with mild obstructive sleep apnea.
- Trial name
- NCT04063917
- Testing
- ZENS
- Where
- 2 sites in Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Zennea Technologies Inc.
Adenotonsillectomy, Obstructive Sleep Apnea (OSA)
Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstructive Sleep Apnea
Emphasize that the usage of multimodal analgesia in managing perioperative pain in children with mild to moderate Obstructive Sleep Apnea undergoing adenotonsillectomy may achieve the same efficacy of fentanyl with less…
- Conditions
- Adenotonsillectomy, Obstructive Sleep Apnea (OSA), Fentanyl, Opioid
- Trial name
- NCT07435493
- Testing
- Group A: Fentanyl-Based Analgesia, Group B: Opioid-Free Multimodal Analgesia
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
Sleep Apnea, Obstructive, Snoring
Different Forms of OMT as Methods for Reducing Snoring and Mild to Moderate Sleep Apnea
Objective the present project aims to assess the impact of 1) oral screen training, group training, and the use of neuromuscular electrical training (NMES) as orofacial myofunctional therapy (OMT) methods for reducing the…
- Trial name
- SNORT (NCT06330116)
- Testing
- IQoro, eXciteosa, Grouptraining
- Where
- 3 sites in Denmark, Sweden
- Volunteers
- 141 people
- Sponsor
- Region Västerbotten
Obstructive Sleep Apnea, Spinal Cord Injuries
Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea
Mild intermittent hypoxia (IH) initiates sustained increases in chest wall and upper airway muscle activity in humans. This sustained increase is a form of respiratory plasticity known as long-term facilitation (LTF).
- Trial name
- NCT03736382
- Testing
- Mild intermittent hypoxia, Continuous positive airway pressure (CPAP)
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- Wayne State University
Apnea, Obstructive
A Study Comparing Two Mandibular Advancement Devices in the Treatment of Sleep Apnea
The goal of this randomised, controlled cross-over study is to compare two mandibular repositioning devices (MRA) already on the market in the treatment of mild-to-moderate obstructive sleep apnea.
- Trial name
- MRA OSA (NCT06810479)
- Testing
- Polygraphy, Questionaire, Question
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- Ziekenhuis Oost-Limburg
Sleep Apnea, Obstructive
Obstructive Sleep Apnea - Patient Specific Factors, Success Rate and Compliance
Obstructive sleep apnea (OSA) is a condition where the patient's breathing cease during sleep due to collapse of the oro-pharynx.
- Trial name
- NCT02953028
- Testing
- CPAP, Mandibular Advancing Splint
- Where
- 2 sites in Norway
- Volunteers
- 119 people
- Sponsor
- University of Tromso
Obstructive Sleep Apnea
Somnodent vs Herbst in Mild and Moderate OSA Patients
Obstructive sleep apnea (OSA) is a common chronic sleep disorder that often requires lifelong care. The prevalence in the Netherlands is estimated around 300.000 patients.
- Trial name
- COSH (NCT02724865)
- Testing
- Somnodent® (Oral appliance therapy), Herbst® (Oral appliance therapy)
- Where
- Netherlands
- Volunteers
- 140 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Patients with Mild Obstructive Sleep Apnea Hypopnea
A Clinical Pharmacology Study of TS-142 in Patients with Obstructive Sleep Apnea Hypopnea.
A study to evaluate the respiratory safety of TS-142 in patients with mild obstructive sleep apnea hypopnea.
- Trial name
- NCT04746105
- Testing
- TS-142
- Where
- Japan
- Volunteers
- 46 people
- Sponsor
- Taisho Pharmaceutical Co., Ltd.
High Flow Nasal Cannula, Obstructive Sleep Apnea
High Flow Nasal Cannula and Conventional Oxygen Therapy in the Postoperative Management of Patients With Mild to Moderate Obstructive Sleep Apnea
This study aims to compare the effectiveness of conventional oxygen therapy oxygen and high-flow nasal cannula therapy on oxygen saturation (SpO2), measuring number of SpO2 drop >4% of base line oxygen saturation (o2 desaturation…
- Trial name
- NCT06306651
- Testing
- High flow nasal cannula therapy group, Conventional oxygen therapy group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Obstructive Sleep Apnea, Mild Cognitive Impairment
Sleep Apnea, Neurocognitive Decline and Brain Imaging in Patients With Subjective or Mild Cognitive Impairment
Obstructive sleep apnea (OSA) is recurrent episodes of partial or complete obstruction of the upper airway during sleep that causes intermittent hypoxia and sleep fragmentation and potentially lead to cardiometabolic and…
- Conditions
- Obstructive Sleep Apnea, Mild Cognitive Impairment, Subjective Cognitive Impairment
- Trial name
- NCT06150352
- Testing
- Continuous Positive Airway Pressure or other management for OSA per clinical indications.
- Where
- Hong Kong
- Volunteers
- 180 people
- Sponsor
- The University of Hong Kong
Sleep Apnea
Long-term Effect of the Physical Activity Promotion on the Clinical Characteristics and Vascular Risk in Patients With Mild-moderate Obstructive Sleep Apnea
Main objective: To assess the effect of the daily physical activity promotion with a pedometer during 12 months on the apnea-hypopnea index (AHI) in patients with mild to moderate obstructive sleep apnea (OSA). Study patients.
- Trial name
- PASOS (NCT03086850)
- Testing
- Promotion of daily physical activity with a pedometer, Conventional treatment
- Where
- Spain
- Volunteers
- 144 people
- Sponsor
- Hospital Universitario La Paz
Sleep Apnea, Obstructive, Hypertension Secondary
Efficiency of Speech Therapy in Resistant Hypertensive Patients With Mild Obstructive Sleep Apnea Syndrome
The purpose of this study is to analyze the effect of speech therapy on quality of life, sleep quality, daytime sleepiness level and apnea-hypopnea index in patients with hypertensive patients with mild obstructive apnea syndrome.
- Trial name
- NCT03753633
- Testing
- Speech therapy, Control
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Apnea, Obstructive Sleep, Obstructive Sleep Apnea
OSA-18 in Children With Mild Obstructive Sleep Apnea: Can it be a Helpful Decision Making Tool?
The concept is a novel research idea that incorporates the potential impact of patient quality of life (QOL) on decision-making for treatment of mild obstructive sleep apnea (OSA).
- Trial name
- OSA-18 (NCT05911646)
- Testing
- OSA-18 Survey, Decisional Conflict (DCS)
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Connecticut Children's Medical Center
Mild Cognitive Impairment, Obstructive Sleep Apnea
Evaluation of Trazodone in OSA-MCI
Alzheimer's disease (AD) is a progressive and multifactorial neurodegenerative disease. Before progressing to AD, individuals may experience mild cognitive impairment (MCI).
- Trial name
- NCT05209035
- Testing
- Trazodone
- Where
- Hong Kong
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Perennial Allergic Rhinitis
Study of Nasonex® in Improving Sleep Disturbances Related to Perennial Allergic Rhinitis (Study P04909)(TERMINATED)
This study will hope to show that the treatment of the patient's perennial allergic rhinitis (PAR) using Nasonex® (mometasone furoate nasal spray) will result in improvement of the nasal symptoms of PAR and of nighttime…
- Trial name
- NCT00491374
- Testing
- Mometasone Furoate Nasal Spray
- Sponsor
- Schering-Plough
Sleep Apnea
Surgical Treatment of Mild Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is one of the most common sleep disorder. There are numerous conditions that are related to OSA, such as diabetes, cardiovascular diseases, and metabolic syndrome.
- Trial name
- NCT00747890
- Testing
- Modified tonsillectomy, Lifestyle counselling by physician
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Kuopio University Hospital
Obstructive Sleep Apnea
Montelukast and Inhaled Nasal Steroid Tx in Adult Obstructive Sleep Apnea (OSA)
In children with mild apnea combined therapy with an inhaled nasal steroid and a medication that decreased nasal congestion (montelukast) was shown to be effective.
- Trial name
- NCT01089647
- Testing
- budesonide and montelukast
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- Romaker & Associates