Clinical trials: Mild Traumatic Brain Injury, Concussion
Concussion, Mild, Convergence Insufficiency
Spectacles Lens in Concussed Kids
We will be looking at 3 treatment arms in the form of different type of glasses to see if one is superior to helping kids have sustained a concussion and are symptomatic.
- Conditions
- Concussion, Mild, Convergence Insufficiency, Accommodation; Insufficiency
- Trial name
- SLICK (NCT03123822)
- Testing
- Glasses
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Concussion Post Syndrome
The Effect of Binasal Occlusion on Balance Following a Concussion
This study evaluates the effect of binasal occlusion (BNO) glasses on balance and eye movement in adults with dizziness after a concussion.
- Trial name
- NCT03355339
- Testing
- Binasal occlusion, No binasal occlusion
- Volunteers
- 40 people
- Sponsor
- University of Ottawa
Concussion, Mild, Concussion; Eye
EYE-SYNC Concussion Classification Study
The purpose of this study is to determine the sensitivity and specificity of an aid in assessment of concussion based on eye-tracking, in comparison to a clinical reference standard appropriate for sport-related concussion…
- Conditions
- Concussion, Mild, Concussion; Eye, Concussion, Brain, Concussion, Severe
- Trial name
- NCT04381767
- Testing
- EYE-SYNC
- Where
- United States
- Volunteers
- 1,303 people
- Sponsor
- Sync-Think, Inc.
Mild Traumatic Brain Injury, Concussion, Post Concussive Syndrome, Chronic
Effect of Mental Imagery in Patients With Persistent Post-concussion Symptoms
Background: Mild Traumatic Brain Injury (mTBI) often results in persistent emotional, cognitive, and somatic symptoms-such as headaches and dizziness.
- Conditions
- Mild Traumatic Brain Injury, Concussion, Post Concussive Syndrome, Chronic, Post Traumatic Headache
- Trial name
- NCT07166536
- Testing
- Provocation Test for Symptoms Using Mental Imagery
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Reuth Rehabilitation Hospital
Concussion, Mild Traumatic Brain Injury
Impact of a Paced Breathing Exercise Intervention on Autonomic Nervous System Function After Pediatric Concussion (Acute Phase)
The goal of this pilot clinical trial is to assess the feasibility of administering a paced breathing exercise intervention program to children and adolescents in the acute period after concussion.
- Trial name
- Breathe - PED (NCT07572734)
- Testing
- Paced breathing exercises
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Concussion
Evaluation of an EEG Based Concussion System
This study will evaluate the accuracy of a new concussion system at detecting concussions. The investigators will be evaluating the degree to which data collected with the device agrees with a physician's determination of a…
- Trial name
- NCT03710109
- Testing
- EEG
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pediatric Mild Traumatic Brain Injury
IVF in Pediatric Concussion
Children with concussion may improve with intravenous fluids.
- Trial name
- NCT02214316
- Testing
- Hypertonic Saline
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Washington University School of Medicine
Concussion, Sport-Related Concussion
Trial Study of an Exercise Program for Youth With Persistent Symptoms After Concussion
The purpose of this randomized control trial study is to determine if an active rehabilitation (low intensity exercise program) in combination with a comprehensive education intervention (standard care) is more effective than the…
- Conditions
- Concussion, Sport-Related Concussion, Mild Traumatic Brain Injury
- Trial name
- NCT02257749
- Testing
- Active Rehabilitation, Comprehensive Education Intervention (Standard Care)
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Acquired Brain Injury
The Parkwood Pacing and Planning™ App
In efforts to assist people who have had a concussion (mild traumatic brain injury), the Parkwood Pacing and Planning™ app has been developed and tested and will be released to the public.
- Trial name
- NCT03957343
- Testing
- Pacing and Planning App
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Mild Traumatic Brain Injury, Posttraumatic Stress Disorder
Improving Cognitive Rehabilitation Outcomes
Posttraumatic stress disorder (PTSD) and mild TBI (mTBI) frequently co-occur in post-9/11 Veterans, and together are associated with worse cognitive performance, mental health, everyday functioning, community integration, quality…
- Trial name
- NCT07055633
- Testing
- CCT+MBLT, CCT+ION
- Where
- 2 sites in United States
- Volunteers
- 144 people
- Sponsor
- VA Office of Research and Development
Brain Concussion, Mild Traumatic Brain Injury
Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
This study aims to examine the long-term effect of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, on chronic headaches following mild traumatic brain injury (mTBI).
- Conditions
- Brain Concussion, Mild Traumatic Brain Injury, Headache, Post-Concussion Symptoms
- Trial name
- NCT06112093
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Traumatic Brain Injury
Subsymptom Threshold Exercise Protocol Following Mild TBI
The study will monitor outcomes of two interventions to develop a best practice in the treatment of mild Traumatic Brain Injury (mTBI).
- Trial name
- STEP (NCT02267668)
- Testing
- STEP, Control
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University Hospitals Cleveland Medical Center
Traumatic Brain Injury
Amyloid Accumulation After Mild Traumatic Brain Injury
There will be 200 participants, who aged 30 years or older with TBI in 1,5,10,15 years ago and GCS=13-15 will be recruited. Another group of 200 participants with the same age and gender and without TBI will be recruited as the…
- Trial name
- NCT01871610
- Testing
- [18F]AV-45 PET amyloid binding imaging
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Mild Traumatic Brain Injury
Standardized Instruments to Provide Diagnostic and Prognostic Information in Mild Traumatic Brain Injury (mTBI)
This study will establish the capability of a suite of conventional tests and the Neurolign Dx_100 I-PAS goggle system to reliably and objectively detect mTBI in an acute setting when comparing individuals with mTBI to controls…
- Trial name
- NCT04372797
- Testing
- Diagnostic test
- Where
- 3 sites in United States
- Volunteers
- 161 people
- Sponsor
- Carey Balaban
Traumatic Brain Injury, Mild Traumatic Brain Injury
Effect of Graded Aerobic Exercise in Mild Traumatic Brain Injury
There is a paucity of knowledge about mechanisms behind mild traumatic brain injury (mTBI) subgroup's sustained problems, and effective interventions that can alleviate this disabling condition.
- Trial name
- NCT06177509
- Testing
- Graded Aerobic Exercise
- Where
- 2 sites in Norway
- Volunteers
- 72 people
- Sponsor
- Sunnaas Rehabilitation Hospital
Traumatic Brain Injury, Concussion
Enhancing Cognitive and Neurobehavioral Functions After Repetitive Traumatic Brain Injuries (rTBI) in Retired NFL Players and Military Veterans.
The purpose of this study is to compare different combinations of cognitive training in retired professional football players and military veterans with a history of repeated concussions and persistent symptoms of impaired…
- Conditions
- Traumatic Brain Injury, Concussion, Mild Cognitive Disorder
- Trial name
- NCT02699476
- Testing
- Psycho-Social Therapy, Cognitive Behavioral Computer Training, Interactive Trainer-Subject Sessions
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brain & Body Health Foundation
Post Concussion Syndrome
Effects of Osteopathic Treatment on Vestibular Disturbed Active Post Concussed Individual
The proposed study is a randomized clinical trial with the purpose of determining the efficacy of osteopathic treatment on vestibular symptoms of the post concussed vestibular disturbed athlete as determined by the Dizziness…
- Trial name
- PCS (NCT01962883)
- Testing
- Osteopathic treatment
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Collège d'Études Ostéopathiques
Concussion, Intermediate
Magnesium and Riboflavin Treatment for Post-Concussion Headache
This clinical trial will try to determine if the supplements magnesium and riboflavin will reduce the pain and duration of headaches in persons diagnosed with a concussion.
- Trial name
- NCT06260072
- Testing
- magnesium and riboflavin supplement
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of Virginia
Traumatic Brain Injury
Effects of LEDs on Memory in TBI Patients
The purpose of the study is to investigate whether transcranial, high-intensity LED placed on the scalp can improve working memory in people who have sustained a concussion with lingering effects or a mild brain injury.
- Trial name
- LED (NCT01598532)
- Testing
- MedX Health Phototherapy (light therapy)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Spaulding Rehabilitation Hospital
Mild Traumatic Brain Injury, Acute Brain Injury
Aerobic Exercise for Concussion
The use of aerobic exercise treatment in the chronic phase of concussion recovery is well-described in the literature but there are limited existing data on the effect of exercise treatment in the acute phase after sport-related…
- Conditions
- Mild Traumatic Brain Injury, Acute Brain Injury, Brain Concussion
- Trial name
- NCT02959216
- Testing
- Aerobic Exercise, Stretching Exercise
- Where
- 3 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia