Clinical trials: Mild Traumatic Injury
Mild Traumatic Brain Injury, Alexithymia
Clinical Trial Comparing the Efficacy of Two Teletherapy Programs at Improving Psychological Health in People With Brain Injury
The purpose of the study is to test two different training programs to find out which is better at helping people with a concussion or mild TBI (mTBI) improve their emotional health and well-being.
- Trial name
- NCT07436754
- Testing
- Program 1, Program 2
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Hackensack Meridian Health
Traumatic Brain Injury, Acute Brain Injuries
Vagus Nerve Stimulation to Treat Moderate Traumatic Brain Injury
The purpose of this single-center, prospective, randomized (1:1), double-blind, sham-controlled parallel-arm pilot study is to provide initial evidence of use of the noninvasive vagus nerve stimulator for treatment in patients…
- Trial name
- NCT02974959
- Testing
- gammaCore active device
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- CentraCare
Subjects With Liver Function Injury, Normal Liver Function Subject
A Study in Subjects With Liver Function Injury and Subjects With Normal Liver Function
Evaluate the pharmacokinetic differences of the main metabolite 116-N1 of JT001 in subjects with mild and moderate liver function impairment and those with normal liver function, providing a basis for formulating clinical…
- Trial name
- NCT06093230
- Testing
- Deuremidevir Hydrobromide Tablets
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Shanghai Vinnerna Biosciences Co., Ltd.
PTSD
Non-invasive Nerve Stimulation and Sleep
People often have difficulty sleeping. Reasons are many. But, difficulty falling and staying asleep are common issues. Sleep difficulties are common in disorders such as Post Traumatic Stress Disorder.
- Trial name
- NINS (NCT04021537)
- Testing
- non-invasive nerve stimulation
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Injuries, Head, Traumatic Brain Injuries
Point of Care Testing in Emergency Departments After Mild Traumatic Brain Injury
Traumatic brain injury (TBI) is estimated to have the highest incidence of all common neurological disorders, affecting 50 to 60 million people worldwide each year.
- Trial name
- POCkET (NCT07129577)
- Volunteers
- 400 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Brain Concussion
LED Therapy for the Treatment of Concussive Brain Injury
A double blind randomized trial of light-emitting diode (LED) therapy for patients suffering from mild traumatic brain injury (mTBI).
- Trial name
- NCT02383472
- Testing
- MedX Health Console model 1100
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Boston Children's Hospital
Mild Traumatic Brain Injury
Efficacy of Multidimensional Management of Mild Traumatic Brain Injury
Unfavorable outcomes (UO) are seen in 15 to 20% of patients with mild traumatic brain injury (mTBI). Early identification of patients at risk for UO is crucial for suitable management to be initiated, increasing their chances for…
- Trial name
- NCT03811626
- Testing
- cognitive-behavioral rehabilitation
- Where
- 6 sites in France
- Volunteers
- 221 people
- Sponsor
- Institut de Recherche sur la Moelle épinière et l'Encéphale
Mild Traumatic Brain Injury
BLOOD BIOMARKERS in PAEDIATRIC MTBI
The goal of this observational study is to identify blood biomarkers that could help in the management of paediatric patients with mild TBI. The main questions it aims to answer are: 1.
- Trial name
- t-BIOMAP (NCT06233851)
- Where
- Switzerland
- Volunteers
- 600 people
- Sponsor
- Pediatric Clinical Research Platform
Brain Injury Traumatic Mild
Web-Based Self-Monitoring Activity-Restriction and Relaxation Training Program for Kids With Mild Traumatic Brain Injury
SMART is an interactive web-based program that will allow youth with mild traumatic brain injuries (mTBI) to monitor their symptoms and receive education on problem-solving and coping strategies.
- Trial name
- SMART (NCT03498495)
- Testing
- Self-Monitoring Activity-restriction and Relaxation Training (SMART)
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Brain Concussion, Post-Concussion Syndrome
Early Intervention Programme for Young Patients (Aged 15 - 30 Years) With Symptoms Following Concussion.
Background: Five - 15 % of patients with concussion continue to experience impairing physical, cognitive and emotional symptoms longer than 3 months post-injury.
- Trial name
- NCT02337101
- Testing
- Enhanced Usual Care (EUC), EUC + Early intervention programme
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- University of Aarhus
Mild Cognitive Impairment
Magnetic Brain Stimulation in the Treatment of Mild Cognitive Impairment
This is a pilot study to test the efficacy of repetitive transcranial magnetic stimulation (rTMS) on cognitive improvement in individuals with mild cognitive impairment (MCI).
- Trial name
- NCT02420522
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of Manitoba
Mild Traumatic Brain Injury
Balance and Mild Traumatic Brain Injury: The Effect of a Weighted Compression Vest
After a mild traumatic brain injury (mTBI) people often report balance problems. At Parkwood hospital we have noticed that balance is improved when patients with mTBI wear a weighted compression vest.
- Trial name
- NCT02084329
- Testing
- Weighted Compression Vest
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Minor Head Injury
Outcome of Patients With Mild Head Injury and Presence of an Acute Traumatic Abnormality on CT Scan of Head
Background: Patients with mild blunt traumatic brain injury (TBI) are frequently transferred to Level 1 trauma centers (L1TC) if they have any positive finding of any acute intracranial injury identified on a CT scan of the head.
- Trial name
- NCT04143347
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Massachusetts General Hospital
Concussion Post Syndrome, Headaches Posttraumatic
Pediatric Concussion Outcomes
This is a randomized, placebo-controlled, double-blinded trial in which subjects with a post concussive headache meeting inclusion criterion will be assigned to one of two treatment groups: placebo or nortriptyline.
- Conditions
- Concussion Post Syndrome, Headaches Posttraumatic, Mild Traumatic Brain Injury
- Trial name
- PeCon (NCT04226365)
- Testing
- Nortriptyline
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Lancaster General Hospital
MTBI - Mild Traumatic Brain Injury
Imaging of Injury Mechanism and Interaction of Intestinal Bacteria in Children With Mild Traumatic Brain Injury
Traumatic brain injury (TBI) is the leading cause of disability in children and young adults. Children with moderate to severe TBI are typically at risk of poor functional outcome in terms of neurocognitive impairment and…
- Trial name
- NCT05090007
- Testing
- magnetic resonance image, gut microbiota
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Concussion, Mild
EFFECTS OF VESTIBULAR REHABILITATION THERAPY (VRT) ON BALANCE, SPEED AND AGILITY IN POST-CONCUSSION FOOTBALL PLAYERS
Traumatic brain injury (TBI) is one and utmost rampant attained neurological conditions which can happen in young adults. Vestibular Rehabilitation Therapy can help them improve their balance, speed and agility.
- Trial name
- NCT04487821
- Testing
- Cawthorne Cooksey Exercises
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Zohra Institute of Health Sciences
Mild Traumatic Brain Injury, Post-Concussion Syndrome
Treatment of Insomnia for Adolescents With Mild Traumatic Brain Injury
A substantial number of children and adolescents sustain a mild traumatic brain injury (mTBI) each year. Although research supports that the vast majority of youth will recover quickly and return to normal functioning, some…
- Conditions
- Mild Traumatic Brain Injury, Post-Concussion Syndrome, Insomnia
- Trial name
- NCT03688984
- Testing
- Cognitive Behavioural Therapy for Insomnia
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of Calgary
Dizziness, Brain Injury
Vestibular Consequences of Blast-related Mild Traumatic Brain Injury (TBI)
The purpose of this project is to determine the effects of mild traumatic brain injury and blast exposure on the inner ear balance and central nervous systems.
- Trial name
- NCT01021137
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Post-Concussion Syndrome
Rehabilitation in Post Concussion Syndrome
This project evaluates and quantifies the effects of an individually tailored exercise program applied to patients with long-lasting symptoms after concussion, minor traumatic brain injury, so-called Post-Concussion Syndrome…
- Trial name
- REPCon (NCT05785000)
- Testing
- Physical exercise programme as an add-on, Control patients receiving usual care
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Right Hemispheric Stroke, Left Hemispheric Stroke
Neural and Cognitive Correlates of Pragmatic Abilities
Pragmatics of language refers to the set of abilities that allow one to use and interpret language according to context and, in general, to communicate effectively.
- Conditions
- Right Hemispheric Stroke, Left Hemispheric Stroke, Traumatic Brain Injury, Right Hemispheric Brain Tumor
- Trial name
- APACS_Neuro (NCT06297044)
- Testing
- Neuropsychological assessment
- Where
- Italy
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy