Clinical trials: Mild Traumatic Injury
Post-traumatic Stress Disorder (PTSD), Mild Traumatic Brain Injury (mTBI)
Acupressure and Stress Resilience
The current study will assess the efficacy of acupressure, a type of complementary and alternative medicine (CAM) in the Veteran population.
- Trial name
- NCT01614444
- Testing
- Active Acupressure Treatment
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- VA Eastern Colorado Health Care System
Mild Traumatic Brain Injury
Sensorimotor Stimulation, Routine Physical Therapy, Balance, Cognitive Performance Mild Traumatic Brain Injury Patients
Study design: Randomized controlled trial Settings: Physiotherapy department of Allied hospital, Faisalabad Sample size: 27 in each group Control group receive: Routine physical therapy Experimental group receive: Routine…
- Trial name
- NCT05194644
- Testing
- Routine physical therapy+ Sensorimotor stimulation, Routine physical therapy
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- University of Lahore
Mild Traumatic Brain Injury
Long Term Results of Psychoeducation and Cognitive Rehabilitation After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) accounts for 70-90% of brain injuries, with 600 cases of mTBI per 100 000 people in the united states, but only 100-300 mTBI patients per 100 000 people receive hospital-based care.
- Trial name
- ReLoT-TCCL (NCT04746716)
- Testing
- Phone call
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Concussion, Mild, Convergence Insufficiency
Effect of Vergence Exercises for Patients With Convergence Insufficiency After Concussion.
A large proportion of concussion patients with long-term consequences of concussion experience visually related symptoms such as headache, blurred vision, double vision, and fatigue.
- Trial name
- NCT05012384
- Testing
- Vergence exercises (Orthoptic exercises)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Danish College of Optometry and Vision Science
Traumatic Brain Injury
Effects of LEDs on Memory in TBI Patients
The purpose of the study is to investigate whether transcranial, high-intensity LED placed on the scalp can improve working memory in people who have sustained a concussion with lingering effects or a mild brain injury.
- Trial name
- LED (NCT01598532)
- Testing
- MedX Health Phototherapy (light therapy)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Spaulding Rehabilitation Hospital
Traumatic Brain Injury
Effect of Namenda on Short Term Memory and Attention in Patients With Mild to Moderate Traumatic Brain Injury
The purpose of this study is to determine whether memantine (Namenda) improves memory and attention in patients with mild to moderate traumatic brain injury.
- Trial name
- NCT00462228
- Testing
- Memantine
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Missouri-Columbia
Mild Traumatic Brain Injury, Concussion, Chronic Dizziness
Repetitive Transcranial Magnetic Stimulation Paired with Augmented Reality to Alter Concussion Symptoms
This study aims to determine whether the delivery of brain stimulation paired with a balance training task can improve symptoms of dizziness for individuals experiencing these symptoms due to concussion.
- Conditions
- Mild Traumatic Brain Injury, Concussion, Chronic Dizziness, Vestibular Problem
- Trial name
- NCT06735157
- Testing
- Repetitive transcranial magnetic stimulation, Augmented reality vestibular rehabilitation therapy
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- McMaster University
Concussion, Mild, Vestibular Impairment
Association of History of Concussion With Vestibular Impairment and Cognitive Function in Sports Athletes
This study investigates the potential relationship between prior concussions and their impact on both vestibular function and cognitive abilities in athletes participating in sports.
- Conditions
- Concussion, Mild, Vestibular Impairment, Cognitive Impairment
- Trial name
- NCT06340100
- Testing
- find association between vestibular impairment , cognitive fiunction with concussin
- Where
- Pakistan
- Volunteers
- 115 people
- Sponsor
- Riphah International University
Traumatic Brain Injury, Mild Traumatic Brain Injury
Brain Research Assessing Impacts of Neurophysiological Processing Speed Training in Veterans
Older veterans with a history of mild brain trauma exhibit early cognitive challenges, especially in driving-related tasks. This is attributed to alterations in the brain's excitatory/inhibitory (E/I) balance.
- Conditions
- Traumatic Brain Injury, Mild Traumatic Brain Injury, Aging, Cognitive Decline
- Trial name
- BRAIN-SPEED (NCT06217575)
- Testing
- Alpha neurofeedback training, Visual Attention Training
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Mild Traumatic Brain Injury
The Use of the VOMS Tool With Military Personnel to Track mTBI Recovery and RTD Status
The purpose of the proposed project is to determine if the VOMS is an effective screening tool to identify and track recovery of vestibular and ocular motor impairment and symptoms following mTBI, that corpsman-level medical…
- Trial name
- NCT02634944
- Testing
- Vestibular Ocular Motor Screening Tool (VOMS)
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Brain Concussion, Vestibular Disorder
Portable Mixed Reality-based Platform for Assessment of Progress in Multisensory Rehabilitation Strategies Post-TBI
The goal of this comparative pilot study is to provide evidence that Praxis, a portable testbed with low-cost wearable sensors and a mixed reality environment, can deliver effective multisensory rehabilitation exercises with…
- Conditions
- Brain Concussion, Vestibular Disorder, Cognition Disorder, Mild Traumatic Brain Injury
- Trial name
- Praxis (NCT06314464)
- Testing
- Praxis, Supervised cardiovascular exercise
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- BlueHalo
Concussion, Brain, Concussion, Mild
BCAAs in Concussion 2.0
This study is a randomized, placebo-controlled, double-blinded, therapeutic exploratory clinical trial of branched chain amino acids (BCAAs) in the treatment of concussion.
- Conditions
- Concussion, Brain, Concussion, Mild, Concussion
- Trial name
- NCT06829498
- Testing
- BCAA
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Akiva Cohen
Hypoxic-Ischemic Encephalopathy, Brain Injury
Prospective Research in Infants With Mild Encephalopathy
A multicenter observational pilot study will be conducted to determine the natural history of infants with early diagnosis (≤ 6 hrs of age) of mild neonatal encephalopathy (NE) who are not qualified for therapeutic hypothermia.
- Conditions
- Hypoxic-Ischemic Encephalopathy, Brain Injury, Neonatal Seizure
- Trial name
- PRIME (NCT01747863)
- Testing
- Neurologic examination
- Where
- 7 sites in United States, Canada and 2 more
- Volunteers
- 63 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
MTBI - Mild Traumatic Brain Injury, Concussion, Mild Traumatic Brain Injury
Positive Assurance and mTBI
This study will develop and validate a new educational video that provides positive assurance about mild traumatic brain injury (mTBI) recovery for patients with mTBI.
- Trial name
- NCT04982731
- Testing
- Positive Assurance
- Where
- United States
- Volunteers
- 229 people
- Sponsor
- Inova Health Care Services
Brain Concussion, Cerebral Concussion
Use of Eye Movement Tracking to Detect Oculomotor Abnormality in Traumatic Brain Injury Patients
The purpose of this study is to determine the sensitivity and specificity of an aid in assessment of concussion based on eye-tracking, in comparison to a clinical reference standard appropriate for the Emergency Department (ED)…
- Conditions
- Brain Concussion, Cerebral Concussion, Concussion, Intermediate, Concussion, Mild
- Trial name
- DETECT (NCT02776462)
- Testing
- EyeBox CNS
- Where
- 2 sites in United States
- Volunteers
- 321 people
- Sponsor
- Oculogica, Inc.
Head Injury, Minor, Pediatric
Hypertonic Saline for Mild TBI in Pediatric Patients
The purpose of this study is to compare two different treatments (normal saline and hypertonic saline) for concussions to see if one makes more of a difference in symptoms that can occur following concussions.
- Conditions
- Head Injury, Minor, Pediatric, Emergency Department Patient
- Trial name
- NCT07060105
- Testing
- Hypertonic Saline ( 3% Sodium Chloride Saline), Normal Saline (0.9% NaCl)
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Texas at Austin
Post-Traumatic Headache
Behavior Therapy vs Education for Persistent Headache After Mild TBI
This study will test a new treatment, called Headache reprocessing, for persistent post-traumatic headache. The new treatment will be compared to a headache education intervention.
- Trial name
- NCT07229391
- Testing
- Headache reprocessing, Headache education
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- VA Office of Research and Development
Concussion, Brain
A Pragmatic Rehabilitation Intervention: The Active Rehab Study
The strategic objective of this research line is to examine improving short- and long-term outcomes for soldiers following mild traumatic brain injury (mTBI).
- Trial name
- ARM (NCT05320822)
- Testing
- Active Rehab (Group 2), Progressive Return to Activity (Group 1)
- Where
- 2 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Traumatic Brain Injury, Mild Traumatic Brain Injury
Score Predicting Lesion Development on CT Following Mild TBI
Mild traumatic brain injury (mTBI) is one of the most common reasons behind emergency department (ED) visits. A small portion of mTBI patients will develop an intracranial lesion that might require neurosurgical intervention.
- Trial name
- SELECT-TBI (NCT04995068)
- Testing
- Head CT to determine presence of traumatic intracranial lesion
- Where
- Sweden
- Volunteers
- 20,000 people
- Sponsor
- Karolinska Institutet
Mild Traumatic Brain Injury (mTBI), Brain Injury
A Feasibility Study in Combat Athletes With Mild Traumatic Brain Injury
The use of Hyberbaric Oxygen Therapy (HBOT) would be a new treatment plan rather than conventional rest. If effective, this new use technology would add to the clinical treatment among mild traumatic brain injury (mTBI) patients.
- Conditions
- Mild Traumatic Brain Injury (mTBI), Brain Injury, Concussion
- Trial name
- NCT06901310
- Testing
- Hyberbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Michael Harl