Clinical trials: Mild to Moderate Depression
Depression
Effectiveness and Cost-effectiveness of Telephone-delivered Psychotherapy for Depression in Primary Care
The aim of the study is the examination of effectiveness and cost-effectiveness of a telephone-based psychotherapy (Tel-PT) for depression compared to treatment as usual in primary care.
- Trial name
- NCT02667366
- Testing
- Tel-PT, TAU and text messages
- Where
- Switzerland
- Volunteers
- 56 people
- Sponsor
- University of Zurich
Depression
Effect of Electroacupuncture on Treating the First-episode Depression
Depression is a disease that endangers the physical and mental health of all human beings. Only 30-40% of patients with initial episode depression are cured after treatment with antidepressants.
- Trial name
- NCT05818735
- Testing
- electroacupuncture (EA) treatment, Escitalopram 10mg
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Shanghai Municipal Hospital of Traditional Chinese Medicine
Dementia, Alzheimer Disease
Effectiveness of a 3-month Individual Reminiscence Therapy Program in Older Adults With Alzheimer's Disease
This research aims to evaluate the effectiveness of individual Reminiscence Therapy (RT) program, using a simple reminiscence format, to improve the overall cognitive function, mood, and quality of life (QoL) of older adults with…
- Conditions
- Dementia, Alzheimer Disease, Cognitive Impairment
- Trial name
- NCT06812442
- Testing
- Reminiscence therapy
- Where
- 4 sites in Portugal
- Volunteers
- 40 people
- Sponsor
- Rsocialform - Geriatria, Lda
Depression
The Efficacy and Safety of tDCS in Patients With Mild to Moderate Major Depressive Disorder
This study evaluated the effectiveness and safety of improving depressive symptoms by applying tDCS for 6 weeks to patients with mild to moderate depression.
- Trial name
- NCT04720040
- Testing
- Mind STIM
- Where
- South Korea
- Volunteers
- 65 people
- Sponsor
- Ybrain Inc.
Atypical Depression
St. John's Wort Extract LI 160 for the Treatment of Atypical Depression
The aim of tis study is to assess the efficacy and safety of Jarsin® 300 mg as an acute treatment in mild to moderate depression with atypical features.
- Trial name
- NCT00861978
- Testing
- St. John's Wort extract
- Volunteers
- 201 people
- Sponsor
- Cassella-med GmbH & Co. KG
Depressive Symptoms
EVALUATION OF EFFICACY OF SAMEUP IN SUBJECTS WITH DEPRESSION SYMPTOMS: A RANDOMIZED STUDY
This study is planned to assess the efficacy of SAMEUp versus placebo after six weeks of treatment in subjects characterized by depression symptoms according to ICD-10 (International Classification of Diseases - 10th revision)…
- Trial name
- SAMEUP (NCT03932474)
- Testing
- SAMEUp
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Nutrilinea srl
Depression
Nexalin Therapy for the Treatment of Depressive Symptoms
The primary objectives of this Phase II study are to demonstrate the safety of Nexalin Therapy and to investigate the efficacy of Nexalin Therapy.
- Trial name
- NCT00774813
- Testing
- Nexalin 1.3mA Device, Nexalin 15mA device
- Where
- 2 sites in Russia
- Volunteers
- 120 people
- Sponsor
- Kalaco Scientific, Inc.
Depression, Relapsing-remitting Multiple Sclerosis
Combination of Antidepressants and Fingolimod Relapsing-remitting Multiple Sclerosis (RRMS) Patients With Depression
This is a prospective, multi-center, open-label study in Relapsing-remitting Multiple Sclerosis (RRMS) patients with mild to moderate depression treated with selected serotonin reuptake inhibitors (SSRI) or serotonin and…
- Trial name
- REGAIN (NCT01436643)
- Testing
- Venlafaxine, Fluoxetine, Citalopram
- Where
- 25 sites in Germany
- Volunteers
- 54 people
- Sponsor
- Novartis Pharmaceuticals
Mild to Moderate Depression
Pilot Study Using Transcranial Electrostimulation (TESA-HB) Therapy for the Treatment of Depressive Symptoms
This pilot study uses TESA-HB therapy for treatment of depressive symptoms associated with mild and moderate depression episodes.
- Trial name
- TESAHBPilot (NCT03471754)
- Testing
- TESA-HB Transcranial Electronic Stimulation Device
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Annecto LLC
Major Depressive Disorder
Efficacy of Cognitive Behavioral to Hypnotherapeutic Treatment of Depression
The purpose of the study is to compare the efficacy of an Hypnotherapeutic Treatment of Depression to Cognitive Behavioral Treatment of Depression in patients with mild to moderate Major Depressive Episodes.
- Trial name
- NCT02375308
- Testing
- HDT, ACDT
- Where
- Germany
- Volunteers
- 153 people
- Sponsor
- University Hospital Tuebingen
Depression and/or Anxiety in the Mild-to-moderate Range, Cognitive Behavioral Therapy
Internet-Based Cognitive Behavioural Therapy (iCBT) for Anxiety and Depression in Singapore
Cognitive-behavioural therapy (CBT) has a robust evidence base for treating anxiety disorders and depression, including transdiagnostic CBT. Internet-based CBT (iCBT) offers a new approach to delivering these therapies.
- Trial name
- NCT07532551
- Testing
- Internet-delivered cognitive behavioural therapy (iCBT)
- Where
- 3 sites in Singapore
- Volunteers
- 390 people
- Sponsor
- National University of Singapore
Depression
Care Manager - Coordinating Care for Person Centered Management of Depression in Primary Care
The aim of the project is to explore if a complementary addition of a care manager for depression treatment in the primary care setting has positive effects concerning reduction of the patients' depressive symptoms as well as…
- Trial name
- PRIM-CARE (NCT02378272)
- Testing
- care manager for depression
- Where
- Sweden
- Volunteers
- 376 people
- Sponsor
- Göteborg University
Anxiety-depressive Patients Mild to Moderate
Anxiety-depressive Disorder in Primary Care and Cognitive-behavioral Treatment
OBJECTIVE: Evaluate the effectiveness of quality of life score, a cognitive-behavioral intervention by psychologists in the field of primary care in anxiety-depressive patients, mild to moderate, compared with usual care.
- Trial name
- PSICCAPAD (NCT01907035)
- Testing
- A cognitive-behavioral intervention, Usual care
- Where
- 3 sites in Spain
- Volunteers
- 246 people
- Sponsor
- Basque Health Service
Depression Mild, Depression Moderate
Real-time fMRI Neurofeedback for Mild/Moderate Depression
The aim of the study is to compare the effects of the self-regulation (neurofeedback) of the fMRI signal of the prefrontal cortex in depression to ones of more conventional non-pharmacological treatment, primarily, psychotherapy.
- Trial name
- NCT05025904
- Testing
- Real-time fMRI neurofeedback (rt-fMRI NFB), Сognitive behavioral therapy (CBT), EEG neurofeedback (EEG NFB)
- Where
- Russia
- Volunteers
- 33 people
- Sponsor
- Federal Research Center of Fundamental and Translational Medicine, Russian Federation
Dementia, Mild Cognitive Impairment
Virtual Chair Yoga for Older Adults and Caregivers: Randomized Controlled Trial
Over 700,000 Canadians are affected by dementia costing the health care system approximately $10 billion/year. Due to COVID-19, the government has urged individuals over the age of 70 to stay home, putting this population at risk…
- Trial name
- NCT04884529
- Testing
- Chair-yoga program
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lady Davis Institute
Mild to Moderate Depressive Symptoms
Online Self-healing Program
Background. Almost two thirds of adolescents experience a mental disorder before the age of 25. Among mental disorders, depression is one of the most common among young people aged between 15 to 24, with a prevalence of 13.5% to…
- Trial name
- iCBT-A (NCT07374653)
- Testing
- Online Cognitive Behaviural Therapy, Online Relaxation
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- City University of Hong Kong
Mild to Moderate Depressive Symptoms
Effectiveness of Online Group-based Nonviolent Communication Interventions
This is a randomized controlled trial (RCT) to test the effectiveness of nonviolent communication (NVC) intervention for reducing parenting stress to parents with children in primary schools and mild to moderate depression.
- Trial name
- NCT05371002
- Testing
- Online group nonviolent communication (NVC) interventions, Waitlist control group
- Where
- China
- Volunteers
- 250 people
- Sponsor
- The University of Hong Kong
Anxiety Disorder, Chronic Myeloproliferative Disorders
Music Therapy to Ease Pain and Emotional Distress in Patients With Hematologic Cancer Who Are Undergoing High-Dose Therapy and Stem Cell Transplantation
RATIONALE: Music therapy may be effective in relieving pain and emotional distress in patients who are undergoing cancer therapy.
- Conditions
- Anxiety Disorder, Chronic Myeloproliferative Disorders, Depression, Lymphoma
- Trial name
- NCT00014482
- Testing
- pain therapy, psychosocial assessment and care
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Anxiety, Mild to Moderate Depression
Trial of Prompt Mental Health Care
Anxiety and depression are among the most common mental disorders in the population. Anxiety and depression have significant consequences at the individual, family and community level, and mental illness is estimated to cost the…
- Trial name
- NCT03238872
- Testing
- Cognitive Behavioural Therapy, Treatment as usual
- Where
- 2 sites in Norway
- Volunteers
- 774 people
- Sponsor
- Norwegian Institute of Public Health
Mild to Moderate Anxiety and Depression
Digital Positive Affect Intervention Study
Anxiety and depression are highly prevalent mental health disorders that impose a significant burden on individuals and public health systems worldwide (GBD 2019 Mental Disorders Collaborators, 2022).
- Trial name
- NCT06978257
- Testing
- Digital positive affect intervention (PAI), Self-monitoring intervention
- Where
- Singapore
- Volunteers
- 2,400 people
- Sponsor
- National University of Singapore