Clinical trials: Mild-to-moderate Depression
Anxiety, Depression - Major Depressive Disorder
Integrative Group Psychotherapy (Terebenin's Method) in Adults With Subclinical and Mild/Moderate Anxiety and Depression
Title Pilot Randomized Controlled Trial of an Integrative Group Psychotherapy (Terebenin's Method) in Adults with Subclinical and Mild/Moderate Anxiety and Depression Summary and Detailed Description (Single Text Block) Anxiety…
- Trial name
- NCT06863948
- Testing
- Teribenin method, Control Interventions
- Where
- Russia
- Volunteers
- 66 people
- Sponsor
- S.LAB (SOLOWAYS)
Depression
Adherence to the iFightDepression Online Self-help Tool for Mild and Moderate Depression
Background Computerized cognitive behavioural therapy (cCBT) is proven to be an effective self-help tool for preventing depression and suicide.
- Trial name
- NCT04363086
- Testing
- iFightDepression online self-help tool, Treatment as Usual, phone call
- Where
- Hungary
- Volunteers
- 73 people
- Sponsor
- Semmelweis University
Internet-based Treatment for Depression
Internet Delivered Intervention Program for the Prevention and Treatment of Depression
The purpose of this study is to determine the differential effectiveness of a self applied treatment delivered via Internet for the prevention and treatment of depression, with or without support by the therapist, compared to a…
- Trial name
- NCT02148354
- Testing
- Smiling is Fun
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Universitat Jaume I
PostPartum Depression
Curio Digital Therapy for the Treatment of Post-partum Depression
Primary Objective: Evaluate the clinical effectiveness of the MamaLift Plus app compared to control (digital sham plus treatment as usual) for the management of PPD in the observed population for a period of 9 calendar weeks.
- Trial name
- SuMMER (NCT05958095)
- Testing
- MamaLift Plus
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Healthcare Innovation Technology Lab
Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission
Internet-Based Program With or Without Telephone-Based Problem-Solving Training in Helping Long-Term Survivors of Hematopoietic Stem Cell Transplant Cope With Late Complications
RATIONALE: A personalized Internet-based program may help improve fatigue, depression, and quality of life in long-term survivors of stem cell transplant.
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities
- Trial name
- NCT00799461
- Testing
- internet-based intervention, questionnaire administration, psychosocial assessment and care
- Where
- United States
- Volunteers
- 1,337 people
- Sponsor
- Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium
Anxiety, Mild to Moderate Depression
Guided Internet-based Interventions in Primary Care Effectiveness-implementation Randomized Controlled Trial
Internet-based cognitive behavioral therapy for anxiety and depression have far-reaching potential to overcome common barriers to accessing evidence-based treatment, such as waiting lists, travel distance and costs.
- Trial name
- INTERMENTAL (NCT05118828)
- Testing
- Guided internet-based cognitive behavioural therapy, Treatment as usual in Prompt Mental Health Care (TAU-PMHC)
- Where
- 6 sites in Norway
- Volunteers
- 1,000 people
- Sponsor
- Norwegian Institute of Public Health
Depression
Magnesium Sulfate Versus 5% Dextrose With Treatment Resistant Depression
The proposed study is a 1-week, randomized, double-blind, placebo-controlled, trial to evaluate the efficacy of an IV infusion of magnesium sulfate on symptoms of treatment resistant mild and moderate depression in 20 males and…
- Trial name
- NCT01597167
- Testing
- Magnesium sulfate
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Miami
Mild-to-moderate Depression, Neural Activity
Probiotics for Depressive Symptomatology and Neural Activity.
This study aims to investigate the acute and chronic effects of 16-week probiotic supplementation (Ecologic® Barrier) on depressive symptoms and neural activity in those with mild-to-moderate depression.
- Conditions
- Mild-to-moderate Depression, Neural Activity, Executive Function (Cognition)
- Trial name
- PRODAN (NCT07667530)
- Testing
- Ecologic® Barrier
- Where
- United Kingdom
- Volunteers
- 76 people
- Sponsor
- University of Reading
Exercise, Physical Fitness
Internet-based Physical Activities Randomized Controlled Trial in Mild/Moderate Depression Participants: SONRIE Project
The goal of this randomized controlled trial is to determine the effect of an intervention program with physical activity for 12 weeks on depression, social and emotional well-being and quality of life and health in adults with…
- Conditions
- Exercise, Physical Fitness, Depression, Adult ALL
- Trial name
- SONRIE (NCT05849792)
- Testing
- Exercise and psychological intervention
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- University of Cadiz
Depression and/or Anxiety in the Mild-to-moderate Range, Stress (Psychology)
SanaMente: A Peer-Led Program to Reduce Health Disparities in Rural Latino/a Communities
The goal of this clinical trial is to evaluate the feasibility, acceptability, and preliminary effectiveness of the SanaMente peer-led mental health and lifestyle program for rural Latino/a adults with chronic medical conditions…
- Conditions
- Depression and/or Anxiety in the Mild-to-moderate Range, Stress (Psychology), Chronic Medical Illness
- Trial name
- SanaMente (NCT07705776)
- Testing
- SanaMente
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Depression, Anxiety
Group Cognitive Behavioral Therapy (CBT) Intervention for Women With Mild to Moderate Depression
The purpose of this study is to develop a structured CBT group intervention for women with depression of mild or moderate severity and to pilot a randomized controlled trial to compare this intervention with usual care in…
- Trial name
- BackonTrack (NCT00663078)
- Testing
- Brief CBT Group therapy
- Where
- 2 sites in United Kingdom
- Volunteers
- 75 people
- Sponsor
- University of Bristol
Mild to Moderate Depression
EMI Therapy for Depression in Hong Kong
To determine if a two-week ecological momentary intervention (two EMA + one EMI daily) as augmentation to treatment as usual would reduce depressive symptoms, rumination levels, and functioning in subjects with mild to moderate…
- Trial name
- NCT06430476
- Testing
- EMI, EMA
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Major Depressive Disorder
Alleviating Stress by Mobile Application' for Depression
This study is a single-blind, multicenter, randomized, controlled crossover trial. The App, developed in South Korea, is an application that provides integrated interventions for stress reduction for the general population.
- Trial name
- ASMA-D (NCT05312203)
- Testing
- the App
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- Korea University Guro Hospital
Depression, Anxiety
Mindfulness Based Cognitive Therapy (MBCT) for Primary Care Patients
This study is done to evaluate the effects of Mindfulness Based Cognitive Therapy (MBCT) for primary care patients that have mild to moderate symptoms of depression and anxiety.
- Trial name
- NCT03272516
- Testing
- Mindfulness based cognitive therapy (MBCT), Treatment as usual (TAU)
- Where
- 2 sites in Iceland
- Volunteers
- 120 people
- Sponsor
- University of Iceland
Ischemic Stroke, Depressive Symptoms
Combined tDCS and Cognitive Neurorehabilitation in Post-Stroke Depression
This study evaluates a multimodal intervention pathway for affective and cognitive symptoms after ischemic stroke. Patients undergo an initial screening of depressive symptoms, cognitive function, and quality of life.
- Trial name
- CACTUS (NCT07848919)
- Testing
- Active transcranial direct current stimulation, Cognitive neurorehabilitation using Guttmann NeuroPersonalTrainer
- Where
- Spain
- Volunteers
- 33 people
- Sponsor
- Institut de Recerca Biomèdica de Lleida-Fundació Dr. Pifarré (IRBLleida)
Mood
The Safety and Efficacy of MoodElite T-4003-1 on Improving Mood in a Healthy Adult Population With Mild to Moderate Depressive Symptoms Not Eligible for Therapeutic Intervention
The objective of this study is to investigate the efficacy and safety of MoodElite T-4003-1 on improving mood in a healthy adult population with mild to moderate depressive symptoms not eligible for therapeutic intervention.
- Trial name
- NCT05318456
- Testing
- MoodElite T-4003-1, Comparator
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Chenland Nutritionals Inc.
Anxiety Disorder, Chronic Myeloproliferative Disorders
Music Therapy to Ease Pain and Emotional Distress in Patients With Hematologic Cancer Who Are Undergoing High-Dose Therapy and Stem Cell Transplantation
RATIONALE: Music therapy may be effective in relieving pain and emotional distress in patients who are undergoing cancer therapy.
- Conditions
- Anxiety Disorder, Chronic Myeloproliferative Disorders, Depression, Lymphoma
- Trial name
- NCT00014482
- Testing
- pain therapy, psychosocial assessment and care
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Anxiety, Mild to Moderate Depression
Trial of Prompt Mental Health Care
Anxiety and depression are among the most common mental disorders in the population. Anxiety and depression have significant consequences at the individual, family and community level, and mental illness is estimated to cost the…
- Trial name
- NCT03238872
- Testing
- Cognitive Behavioural Therapy, Treatment as usual
- Where
- 2 sites in Norway
- Volunteers
- 774 people
- Sponsor
- Norwegian Institute of Public Health
Depression
Nexalin Therapy for the Treatment of Depressive Symptoms
The primary objectives of this Phase II study are to demonstrate the safety of Nexalin Therapy and to investigate the efficacy of Nexalin Therapy.
- Trial name
- NCT00774813
- Testing
- Nexalin 1.3mA Device, Nexalin 15mA device
- Where
- 2 sites in Russia
- Volunteers
- 120 people
- Sponsor
- Kalaco Scientific, Inc.
Depression Mild, Depression Moderate
Treatment of Depression Using a Mobile Application in the Dominican Republic
The overall objective of this study is to develop a feasible and acceptable mental health app which delivers Cognitive Behavioral Therapy (CBT) for depressed patients in the Dominican Republic.
- Trial name
- NCT04948996
- Testing
- El Buen Consejo Móvil- Group (EBCM-G), El Buen Consejo Móvil- Individual (EBCM-I)
- Where
- 2 sites in United States, Dominican Republic
- Volunteers
- 27 people
- Sponsor
- Northern Illinois University