Clinical trials: Military Operations
Sleep
Kavalactones on Sleep and Cortisol in Healthy Special Forces Trainees
This research study is being done to better understand the effects of kava supplementation on sleep quality and salivary cortisol in the context of the acute physical and psychological stress of military special forces…
- Trial name
- NCT05381025
- Testing
- Kava (Piper methysticum) extract
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Thorne HealthTech, Inc
Military Training
The Effects of Probiotic and HMB Supplementation on Immune and Digestive Function in Special Operations Soldiers
The study will determine whether acute ingestion of a probiotic combined with beta-hydroxy-beta-methylbutyrate (HMB) can enhance immune and digestive function in soldiers during 8-weeks of advanced infantry training.
- Trial name
- NCT02762968
- Testing
- HMB, BC30
- Where
- Israel
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Metabolic Technologies Inc.
Military Operations, Military Activity
Comprehensive and Continuous Status Measurement of Pre- and Post-Deployment Warfighters With Mobile Application
In this study, we aim to continuously and comprehensively measure the mental and physical status of US Military Special Operation Forces (SOF) through a confidential and cybersecure research mobile application (app) over a…
- Trial name
- NCT04672811
- Testing
- Study App and Apple Watch
- Where
- 2 sites in United States
- Volunteers
- 595 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Breast Cancer, Shoulder
Morbidity After Diagnosis and Treatment of Breast Cancer Patients
This study will examine the frequency and severity of problems in women with breast cancer for 2 years following initial medical treatment, including: Physical impairments, such as loss of strength or flexibility, increased…
- Conditions
- Breast Cancer, Shoulder, Lymphedema, Fatigue
- Trial name
- NCT00027118
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Posttraumatic Stress Disorder
PROlonGed ExpoSure Sertraline
The current research study aims to compare the effectiveness of two proven treatments for posttraumatic stress disorder (PTSD): Prolonged Exposure (PE), sertraline, and their combination.
- Trial name
- PROGrESS (NCT01524133)
- Testing
- Sertraline, Prolonged Exposure Therapy
- Where
- 4 sites in United States
- Volunteers
- 223 people
- Sponsor
- VA Ann Arbor Healthcare System
Traumatic Brain Injuries
Telehealth-Education-Based Program for Military Caregivers of Injured Service Members With Head Injuries
The primary purpose of this research is to evaluate the impact of a telehealth-based, cognitive behavioral therapy (CBT) intervention (problem-solving training: PST) for adult informal military family/friend caregivers of OIF/OEF…
- Trial name
- NCT02215187
- Testing
- Problem-Solving Training (PST), Attention Control
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Posttraumatic Stress Disorders, Combat Disorders
Integrated Treatment of OEF/OIF Veterans With PTSD & Substance Use Disorders
In comparison to the general population, U.S. military and Veterans are at an increased risk for developing both substance use disorders (SUD) and Post Traumatic Stress Disorder (PTSD).
- Conditions
- Posttraumatic Stress Disorders, Combat Disorders, Alcohol Dependence, Drug Dependence
- Trial name
- COPE (NCT01338506)
- Testing
- Concurrent Treatment with Prolonged Exposure (COPE)
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Medical University of South Carolina
Depressive Symptoms, Anxiety
Evaluation of Mindfulness and Yoga in Basic Combat Training
The present study is a group randomized trial assessing the impact of mindfulness and yoga training on the health, performance, and well-being of soldiers in Basic Combat Training (BCT).
- Conditions
- Depressive Symptoms, Anxiety, Sleep, Emotion Regulation
- Trial name
- NCT05550610
- Testing
- Mindfulness Based Attention Training (MBAT) and Yoga
- Where
- United States
- Volunteers
- 1,896 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Institute of Research (WRAIR)
Machine Learning
Prediction of Risk Factors for Adverse Events After Head and Neck Vascular Recanalization Surgery Based on Machine Learning Models
Prediction of risk factors for adverse events after head and neck vascular recanalization surgery based on machine learning models
- Trial name
- NCT06120478
- Testing
- observe
- Where
- China
- Volunteers
- 1,300 people
- Sponsor
- Tang-Du Hospital
Traumatic Brain Injury, Military Operations
Hyperbaric Oxygen Treatment for Veterans With Traumatic Brain Injury
The goal of this blinded, adaptive, randomized, placebo-controlled clinical trial is to investigate the use of hyperbaric oxygen as a therapy to treat mild to moderate traumatic brain injury in Veterans and active military.
- Trial name
- NCT06581003
- Testing
- Oxygen 99.7 %, Oxygen 21 %
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- University of South Florida
Healthy, Military Operations
Minimal Equipment Training Approach to Improve Warfighter Performance
The purpose of this project is to compare a minimal equipment training program with and without blood flow restriction (BFR) training to periodized concurrent resistance and endurance training.
- Trial name
- NCT05003778
- Testing
- Traditional equipment resistance training, Minimal equipment resistance training, Blood flow restriction training
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Posttraumatic Stress Disorders, Combat Disorders
Prolonged Exposure for Post Traumatic Stress Disorder (PTSD) Among Operation Iraqi Freedom/Operation Enduring Freedom (OIF/OEF) Personnel
The purpose of this study is 1) to evaluate whether massing 10 PE sessions in 2 weeks (massed trials; M-PE) is more efficacious than Minimal Contact control (MCC); 2) whether the massed sessions format retains the efficacy of…
- Trial name
- STRONG STAR (NCT01049516)
- Testing
- Prolonged Exposure Therapy - Massed, Prolonged Exposure Therapy - Spaced, Minimal Contact Control
- Where
- 3 sites in United States
- Volunteers
- 366 people
- Sponsor
- University of Pennsylvania
Breast Cancer, Lymphedema
Morbidity Following the Diagnosis and Treatment of Patients With Breast Cancer
This study will examine the frequency and severity of problems in women with breast cancer during the first year after initial medical treatment, including: Physical impairments, such as loss of strength or flexibility, increased…
- Conditions
- Breast Cancer, Lymphedema, Physical Therapy, Shoulder
- Trial name
- NCT00027105
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Cognitive Impairment
Changes in Cognition During a 24-h Simulated Military Operation
Sustained military operations (SUSOPs) result in psychological stress and cognitive dysfunction, which may be related to the recruitment of classical monocytes into the brain.
- Trial name
- NCT04250480
- Testing
- beta-alanine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Conscripts, Military Induction Board
Prevalence of ENT Diseseas
The aim of the present study will be to evaluate in conscripts at the military induction board the prevalence of rhinosinusitis, the prevalence of HPV vaccinations, the prevalence of hearing impairments and the prevalence of…
- Conditions
- Conscripts, Military Induction Board, ENT Disease, Rhinosinusitis Chronic
- Trial name
- PrENT (NCT06105346)
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Caloric Restriction, Exercise
Trial of Testosterone Undecanoate for Optimizing Performance During Military Operations
The objective of this study is to determine the effects of a single dose of testosterone undecanoate during and in recovery from simulated operational stress.
- Conditions
- Caloric Restriction, Exercise, Sleep
- Trial name
- OPS II (NCT04120363)
- Testing
- Testosterone Undecanoate, Sesame Oil
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Myopia, Myopic Astigmatism
Optical Quality, Threshold Target Identification, and Military Target Task Performance After Advanced Keratorefractive Surgery
To determine the effect of two types of wavefront modalities (WFG vs. WFO) and two types of refractive surgery (PRK vs. LASIK) on visual and military task performance after laser refractive surgery.
- Trial name
- NCT01097525
- Testing
- WFG PRK, WFG LASIK, WFO PRK
- Where
- 2 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Fort Belvoir Community Hospital
Musculoskeletal Injury, Hypogonadism
Adaptions and Resiliency to Multi-Stressor OpeRations
Non-combat-related muscle, tendon and bone injuries are the most common injuries suffered by military personnel, particularly in new recruits.
- Conditions
- Musculoskeletal Injury, Hypogonadism, Hormonal Contraception
- Trial name
- ARMOR (NCT06455969)
- Testing
- Goserelin 3.6 MG, Multi-Stressor Training, Testosterone gel (AndroGel 5g)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bradley Nindl
Inflammation
Effects of Severe Negative Energy Balance on Inflammation
The effects of prolonged negative energy balance, commonly observed in sustained military training and combat operations, on systemic inflammatory responses has not been determined.
- Trial name
- NCT03524690
- Testing
- Energy Balance, Negative Energy Balance
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Intestinal Bacteria Flora Disturbance
Multi-Antibiotic Resistance Carriage in Gut Flora
Prevalence Study evaluating the acquisition of carriage of multidrug-resistant Gram-negative bacteria (MDRGNB) in the gut flora in volunteers of French Armed Forces staying from 4 to 6 months outside France.
- Trial name
- MARC (NCT01591538)
- Where
- France
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Da Volterra