Clinical trials: Mind-Body Therapies
Chronic Pain, Back Pain Lower Back Chronic
Mind-body Treatments for Chronic Back Pain
Participants with chronic back pain will complete an online prescreen. They will then be randomized to one of two different studies: a placebo vs. waitlist study or a psychotherapy vs.
- Conditions
- Chronic Pain, Back Pain Lower Back Chronic, Back Pain, Low
- Trial name
- NCT03294148
- Testing
- Psychotherapy Treatment for Chronic Back Pain
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Chronic Pain, Migraine
Evaluation of a Mind-body Based Application for the Treatment of Chronic/Persistent Pain.
We are investigating the effects of a mind-body based mobile application on the experience of chronic pain. Participants meeting our criteria for chronic pain (confirmed via self-report) will complete an online baseline…
- Conditions
- Chronic Pain, Migraine, Chronic Pain Syndrome
- Trial name
- NCT05090683
- Testing
- Mind-body mobile application
- Where
- Canada
- Volunteers
- 198 people
- Sponsor
- University of the Fraser Valley
Schizophrenia, Schizoaffective Disorder
Second-Generation Antipsychotic Treatment Indication Effectiveness And Tolerability In Youth (Satiety) Study
The purpose of this study is to get a better understanding of the side effect burden and identify predictors of psychotic, mood and aggressive disorders in children and adolescents.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Psychotic Disorder, Not Otherwise Specified
- Trial name
- SATIETY (NCT01269710)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of North Carolina, Chapel Hill
Aggression, Attention Deficit-Hyperactivity
Metabolic Effects of Antipsychotics in Children
The project aims to describe and compare the outcome of 12 weeks of prospective, randomized treatment with olanzapine, risperidone or aripiprazole on insulin action in skeletal muscle, liver and adipose tissue, abdominal fat…
- Conditions
- Aggression, Attention Deficit-Hyperactivity, Oppositional Defiant Disorder, Pervasive Development Disorders
- Trial name
- MEAC (NCT00205699)
- Testing
- risperidone, olanzapine, aripiprazole
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Washington University School of Medicine
Narcolepsy, Narcolepsy Without Cataplexy
Awareness and Self-Compassion Enhancing Narcolepsy Treatment
The overall goal of this research is to test the effectiveness of a mindfulness-based intervention (MBI) for improving health-related quality of life as a complementary practice to standard care for narcolepsy.
- Conditions
- Narcolepsy, Narcolepsy Without Cataplexy, Narcolepsy With Cataplexy
- Trial name
- ASCENT (NCT04306952)
- Testing
- Brief MBI, Standard MBI, Extended MBI
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwestern University
Fibromyalgia
Tai Chi Mind-Body Therapy for Fibromyalgia
The purpose of this study is to obtain preliminary data on the effects of Tai Chi on musculoskeletal pain, fatigue, sleep quality, psychological distress, physical performance,and health status in 60 patients with fibromyalgia.
- Trial name
- NCT00515008
- Testing
- Tai Chi Intervention, Control Intervention
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Tufts Medical Center
Metabolic Complications
Metformin for the Prevention of the Metabolic Side-effects of Zyprexa
We hypothesize that metformin co-administered with olanzapine will be well tolerated and associated with significantly less insulin resistance, weight gain and dyslipidemia as compared to olanzapine plus placebo.
- Trial name
- NCT00682448
- Testing
- Metformin
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Rush University Medical Center
Cardiovascular Diseases in Old Age
Yoga in Older Cardiac Patients
The goal of this clinical trial is to compare, at 3 months, the effects of a yoga intervention on physical health, including balance, muscle strength, physical activity levels, cardiac autonomic function, and physical…
- Trial name
- NCT06235658
- Testing
- Gentle Yoga
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Geunyeong Cha
Bullying, Weight, Body
Cognitive-Behavioral Therapy for Weight-related Bullying (Online Treatment)
This study will perform a clinical trial with adolescents to pilot a new cognitive-behavioral treatment (CBT) for weight-related bullying testing (1) feasibility, (2) acceptability, and (3) initial efficacy.
- Conditions
- Bullying, Weight, Body, Trauma, Psychological
- Trial name
- NCT04587752
- Testing
- CBT for Weight Bullying
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
Eating Disorders, Body Image
FlexED: A Digital, Gamified Early Intervention for Eating Disorders
The goal of this clinical trial is to test a new intervention for body-image distress to reduce eating disorder symptoms in young women and girls between the ages of 15-25 years old.
- Trial name
- NCT05609409
- Testing
- FlexED
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Duke University
Binge-Eating Disorder, Obesity
Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Acute Treatment
Brief Summary: This study will compare the effectiveness of cognitive behavioral therapy (CBT), lisdexamfetamine (LDX), and the combination of CBT and LDX for the treatment of binge-eating disorder in patients with obesity.
- Trial name
- NCT03924193
- Testing
- Lisdexamfetamine Dimesylate, Cognitive-Behavioral Therapy, Combination LDX and Cognitive-Behavioral Therapy
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Yale University
Dementia-related Psychosis
Relapse Prevention Study of Pimavanserin in Dementia-related Psychosis
The purpose of this study is to evaluate the efficacy of pimavanserin compared to placebo in preventing relapse of psychotic symptoms in subjects with dementia-related psychosis who responded to 12 weeks of open label…
- Trial name
- NCT03325556
- Testing
- Pimavanserin 34 mg, Pimavanserin 20 mg
- Where
- 83 sites in United States, Bulgaria and 11 more
- Volunteers
- 392 people
- Sponsor
- ACADIA Pharmaceuticals Inc.
Obesity, Morbid, Insulin Resistance
Stool Transplantation for Treatment of Insulin Resistance in Morbidly Obese Patients
More and more people in Canada and around the world are severely (morbidly) obese, and this is associated with a high risk for poor blood sugar control (insulin resistance, IR) and diabetes.
- Trial name
- NCT02970877
- Testing
- Fecal filtrate from 150 g stool from healthy lean donors, Fecal filtrate from 150 g of the recipient's own stool
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- Johane Allard
Schizophrenia
Atomoxetine for Treatment of Weight Gain in Olanzapine or Clozapine Patients
The study investigates the use of Atomoxetine in combination with exercise and a diet support group (Weight Watchers)to treat weight gain associated with Olanzapine or clozapine.
- Trial name
- NCT00176436
- Testing
- Diet support group, Group counseling and exercise
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Maryland, Baltimore
Obsessive-Compulsive Disorder, Trichotillomania (Hair-Pulling Disorder)
Epidiolex in Obsessive Compulsive Disorder and Related Disorders
The primary objective of the proposed study is to evaluate the safety and efficacy of Epidiolex (cannabidiol) in adults with obsessive compulsive and related disorders (OCRDs).
- Conditions
- Obsessive-Compulsive Disorder, Trichotillomania (Hair-Pulling Disorder), Tourette Syndrome, Hoarding Disorder
- Trial name
- NCT04978428
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Chicago
Hot Flashes, Postmenopausal Symptoms
A Mind-Body Intervention for Hot Flash Management
The long-term goal of this program of research is to determine safe and effective non-hormonal interventions for menopausal symptoms.
- Conditions
- Hot Flashes, Postmenopausal Symptoms, Breast Cancer
- Trial name
- NCT03572153
- Testing
- Self-Administered Hypnosis, Self-Administered White Noise Hypnosis
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Baylor University
MTBI - Mild Traumatic Brain Injury, Anxiety
Live Video Mind-body Treatment to Prevent Persistent Symptoms Following mTBI
The investigator aims to conduct a pilot randomized controlled trial to test the feasibility of two symptom management programs for college-age individuals with recent concussions and anxiety, TOR-C 1 and TOR-C 2.
- Trial name
- NCT05524402
- Testing
- TOR-C 1, TOR-C 2
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Binge-Eating Disorder, Obesity
Behavioral and Pharmacologic Treatment of Binge Eating and Obesity: Maintenance Therapy
This study will test the effectiveness and relative efficacy of naltrexone/bupropion medication as a maintenance therapy for the treatment of binge eating disorder (BED) in patients with obesity.
- Trial name
- NCT03047005
- Testing
- NB medication (Naltrexone Bupropion combination)
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Yale University
Obesity, Overweight
Interactive Obesity Treatment Approach for Obesity Prevention in Adults With Early Serious Mental Illness: iOTA-SMI
Using a design-for-dissemination approach, this application proposes to use combined methods to adapt and pilot test an interactive obesity treatment approach (iOTA) for obesity prevention in early serious mental illness (eSMI)…
- Conditions
- Obesity, Overweight, Severe Mental Disorder
- Trial name
- iOTA-eSMI (NCT03980743)
- Testing
- iOTA text messaging intervention, Health Education text messaging intervention
- Where
- 2 sites in United States
- Volunteers
- 51 people
- Sponsor
- Washington University School of Medicine
Knee Osteoarthritis
Tai Chi and Physical Therapy for Knee Osteoarthritis
We will conduct a large randomized controlled trial comparing the effectiveness and cost-effectiveness of Tai Chi mind-body exercise and standard-of-care Physical Therapy for Knee Osteoarthritis.
- Trial name
- TCPT (NCT01258985)
- Testing
- Tai Chi, Physical Therapy
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Tufts Medical Center