Clinical trials: Minimally Invasive Cardiac Surgery
Coronary Artery Disease
MIDCAB Versus DES in Proximal LAD Lesions
Percutaneous coronary intervention with a sirolimus-coated stent compared to minimally invasive bypass surgery in patients with isolated proximal left anterior descending coronary arteries in terms of non-inferiority of an end…
- Trial name
- NCT00299429
- Testing
- Stenting and minimally invasive bypass surgery, PCI with DES
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- University of Leipzig
Mitral Regurgitation, Pain, Postoperative
Cryoablation of Intercostal Nerves for Pain Management in Early Postoperative Period in Patients With Minimally Invasive Mitral Valve Surgery
A single-center, pilot, prospective, randomized clinical trial with a 1:1 allocation ratio. The aim of our trial is to determine whether cryoablation of intercostal nerves provides a clinically significant analgesic effect, which…
- Trial name
- BLOCK (NCT06443931)
- Testing
- cryoablation of intercostal nerves
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Aortic Valve Disease, Aortic Stenosis
EDWARDS INTUITY Elite Valve System
The purpose of this active, observational, open-label, non-randomized, post-market surveillance study is to confirm that EDWARDS INTUITY Elite reduces cross clamp time (XCT) in MIS setting when compared to published data with a…
- Trial name
- MISSION (NCT02907463)
- Where
- 23 sites in Austria, Denmark and 7 more
- Volunteers
- 280 people
- Sponsor
- Edwards Lifesciences
Cardiac Disease
Exparel in Minimally Invasive Cardiac Surgery
The investigators are presently using Exparel, a slow released local anesthestic, in patients undergoing minimally invasive cardiac surgery.
- Trial name
- NCT02008370
- Testing
- Exparel infiltration
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Maimonides Medical Center
Postoperative Atrial Fibrillation
The Effect of Ligament of Marshall Excision During Minimally Invasive Cardiac Surgery-Coronary Artery Bypass Grafting (MICS-CABG) on the Prevention of Postoperative New-Onset Atrial Fibrillation: A Multicenter, Prospective, Randomized, Triple-Blinded Study
After heart bypass surgery, many patients develop a heart rhythm problem called postoperative atrial fibrillation, or POAF for short. This issue happens to 20%-40% of all bypass patients.
- Trial name
- NCT07755072
- Testing
- MICS-CABG combined with excision of the Ligament of Marshall
- Where
- China
- Volunteers
- 628 people
- Sponsor
- Peking University Third Hospital
Ischemic Heart Disease
Safety and Efficacy of Multivessel Minimally Invasive Coronary Artery Bypass Graft Surgery
the aim of this study is to evaluate safety and efficacy of multivessel minimally invasive coronary artery bypass graft surgery through evaluating the possibility of reaching complete revascularization , the complications during…
- Trial name
- NCT03247855
- Testing
- minimal invasive coronary artery bypass graft surgery
- Volunteers
- 60 people
- Sponsor
- Mohammed Farouk Abdel Hafez
Cardiovascular Diseases
Groin Complications in Open Vs. Percutaneous Peripheral Cannulation in Minimally Invasive Cardiac Surgery
The aim of this randomized trial is to investigate the groin complications in open vs percutaneous peripheral cannulation for cardiopulmonary bypass in minimally invasive cardiac surgery
- Trial name
- ProGlide-II (NCT05598385)
- Testing
- Open cannulation, Percutaneous cannulation
- Sponsor
- Jessa Hospital
Minimally Invasive Coronary Revascularization Surgery, Elective Surgery
Impact of Total Coronary Revascularization Via Left Anterior Thoracotomy (TCRAT) vs. Robotic-Assisted Harvesting of LIMA (ITcrats)
The two types of total coronary revascularization via left anterior thoracotomy (TCRAT) might have their potential benefits and disadvantages.
- Trial name
- ITcrats (NCT06988735)
- Testing
- Nonrobotic TCRAT, Robotic TCRAT
- Where
- Saudi Arabia
- Volunteers
- 182 people
- Sponsor
- Mohamed R El Tahan
Pain, Postoperative
Loco-regional Analgesia for Post-operative Pain Management in Cardiac Surgery
The aim of the study is to evaluate whether loco-regional analgesia reduces post operative pain compared to intravenous analgesia, in patients undergoing cardiac surgery in minithoracotomy.
- Trial name
- NCT01903551
- Testing
- Loco-regional catheter
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- University of Turin, Italy
Cardiac Surgery
Erector Spinae Plane Block (ESP) vs Serratus Anterior Plane Block (SAP) for Loco-Regional Analgesia in Adult Patients Undergoing Minimally Invasive Cardiac Surgery Via Mini-Thoracotomy: Impact on Morphine Consumption, Pain Control, and Quality of Recovery
Optimization of postoperative analgesia and reduction of opioid consumption are key components of Enhanced Recovery After Surgery (ERAS) protocols in cardiac surgery.
- Trial name
- SAPESP (NCT07433114)
- Testing
- Serratus anterior plane block (SAP), Erector Spinae Plane block (ESP)
- Where
- Italy
- Volunteers
- 57 people
- Sponsor
- Azienda Socio Sanitaria Territoriale Ovest Milanese, Ospedale di Legnano
Coronary Artery Bypass, Off-Pump
Prospective Cohort Study on Minimal Invasive Coronary Surgery
CABG technology is recognized as the preferred treatment, and its major adverse cardiac and cerebral event(MACCE) incidence and mortality are lower than percutaneous coronary intervention(PCI).
- Trial name
- PCSMICS (NCT04267835)
- Testing
- MIDCAB, thoracotomy OPCABG
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Peking University Third Hospital
Pain, Postoperative
Serratus Planus Block After Minimally Invasive Cardiac Surgery
Many patients receiving MICS (minimally invasive cardiac surgery) suffer from significant postsurgical pain. While systemic analgesic therapy has been proven to be insufficient in a great number of patients, significant unwanted…
- Trial name
- NCT06746272
- Testing
- Serratus Anterior Plane Block
- Where
- Austria
- Volunteers
- 66 people
- Sponsor
- Medical University of Vienna
Cardiac Surgery, Cardiac Diseases
Incisions for Cardiac Surgery
The purpose is to evaluate the investigators' length of incisions based on patient weight, operative times, hospital lengths of stay, pain medicine requirements, complications and costs.
- Trial name
- NCT00229892
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Children's Healthcare of Atlanta
Heart Valve Disease, Postoperative Pain
Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardiac Surgery
This randomized, double-blind, placebo-controlled study aims to evaluate the effect of the serratus posterior superior intercostal plane (SPSIP) block on postoperative pain and opioid consumption in patients undergoing minimally…
- Trial name
- NCT07588230
- Testing
- Serratus Posterior Superior Intercostal Plane Block With Bupivacaine, Serratus Posterior Superior Intercostal Plane Block With Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Cardiac Surgery, Heart Surgery
Novel Venous Cannula Trial
This is a prospective, open-label, single-arm, single-center clinical investigation designed to evaluate the safety and performance of a Novel Venous Cannula during on-pump cardiac surgery requiring transfemoral venous…
- Conditions
- Cardiac Surgery, Heart Surgery, Cardiopulmonary Bypass, Minimally Invasive Surgical Procedures
- Trial name
- NCT07087639
- Testing
- Self-expanding Venous Cannula
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- Eurosets S.r.l.
Cardiac Surgical Procedure
Postoperative Patency of Internal Jugular Vein After Neck Cannula Insertion
The number of patients undergoing Minimally Invasive Cardiac Surgery (MICS) is increasing each year. MICS procedures on atrioventricular valves are usually performed without conventional sternotomy, an alternative approach is…
- Trial name
- NCT02456259
- Testing
- Neck cannula insertion
- Where
- Czechia
- Volunteers
- 110 people
- Sponsor
- University Hospital Hradec Kralove
Serratus Anterior Plane Block, Acute Pain
Combined SAPB in MICS
Minimally invasive cardiac surgery (MICS) has begun to be performed frequently in recent years. Compared to sternotomy, MISC reduces the risk of mediastinitis, leaves a more aesthetic scar, facilitates postoperative…
- Conditions
- Serratus Anterior Plane Block, Acute Pain, Postoperative Analgesia, Minimal Invasive Cardiac Surgery
- Trial name
- NCT06326320
- Testing
- Combined SAPB
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ankara City Hospital Bilkent
Minimally Invasive Cardiac Valvular Surgery
Valvular Surgery: Minimally Invasive vs Conventional Sternotomy
The conventional approach to heart valve operations is through a sternotomy. This involves a vertical incision in the sternum (breastbone) to gain access to the heart and its related structures.
- Trial name
- NCT04514315
- Testing
- Minimally invasive cardiac valvular surgery, Conventional cardiac valvular surgery
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of Calgary
Cardiac Disease Minimally Invasive Cardiac Surgery Postoperative Pain
Fast-Track Anesthesia in Minimally Invasive Cardiac Surgery: Dexmedetomidine and Erector Spinae Plane Block vs Opioid-Based Anesthesia
Enhanced Recovery After Surgery (ERAS) protocols have revolutionized perioperative management by implementing evidence-based, patient-centered strategies that improve clinical outcomes, shorten hospital length of stay, and reduce…
- Trial name
- Esp (NCT07749274)
- Testing
- Dexmedetomidine, Ultrasound-Guided Bilateral Erector Spinae Plane Block (ESPB), Fentanyl
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Atrial Fibrillation
The Occurrence of Atrial Fibrillation After Totally Endoscopic Cardiac Surgery
The aim of this study is to investigate the occurrence of new-onset postoperative atrial fibrillation after totally endoscopic cardiac surgery.
- Trial name
- AFMICS-II (NCT05633797)
- Testing
- FibriCheck
- Where
- Belgium
- Volunteers
- 152 people
- Sponsor
- Jessa Hospital