Clinical trials: Minimally Invasive Cardiac Surgery
Perfusion; Complications
Prevalence and Predictors of Distal Limb Ischemia in Minimally Invasive Cardiac Surgery.
Peripheral arterial cannulation is a necessity for installation of cardiopulmonary bypass in minimally invasive cardiac surgery (MICS). In the vast majority of cases, the femoral artery is the preferred arterial cannulation site.
- Trial name
- NCT04081974
- Testing
- Distal leg perfusion
- Where
- Belgium
- Volunteers
- 280 people
- Sponsor
- Jessa Hospital
Surgery, Postoperative Cognitive Dysfunction
Five Years Follow-up of Neurological Outcome After Minimally Invasive Cardiac Surgery
A monocenter observational study will be started to investigate postoperative cognitive dysfunction 5 years after minimally invasive cardiac surgery.
- Trial name
- FUNOMICS (NCT05330260)
- Testing
- neurocognitive test battery
- Where
- Belgium
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Heart Valve Diseases or Prosthesis, Aortic Valve Stenosis
Comparison of Early Postoperative Outcomes Between Minimally Invasive Valve Surgery Via Right Thoracotomy and Conventional Valve Surgery Via Sternotomy.
This randomized controlled trial aims to compare early postoperative outcomes between Minimally Invasive Valve Surgery (MIVS) via right thoracotomy and Conventional Valve Surgery via median sternotomy in patients undergoing…
- Conditions
- Heart Valve Diseases or Prosthesis, Aortic Valve Stenosis, Aortic Valve Insufficiency, Valvular Heart Disease Stenosis and Regurgitation (Diagnosis)
- Trial name
- NCT07251660
- Testing
- Minimally Invasive Valve Surgery, Conventional Valve Surgery
- Volunteers
- 32 people
- Sponsor
- Chaudhry Pervaiz Elahi Institute of Cardiology
Periareolar Minimally Invasive Cardiac Surgery
Periareolar Approach in Minimally Invasive Cardiac Surgery
Overall Goal: To study the feasibility and safety of "periareolar minimally invasive surgery" protocol in patients undergoing periareolar minimally invasive surgery vs. Control group (inframammary approach).
- Trial name
- PAMI (NCT04726488)
- Testing
- Periareolar Approach in Minimally Invasive Cardiac Surgery (PAMI Technique), inframammary approach
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pathological Processes, Cardiomyopathies
Adenosine as an Adjunct to Blood Cardioplegia
Myocardial protection is a major issue in cardiac surgery, since inadequate protection increases the risk of postoperative cardiac dysfunction.
- Trial name
- NCT02681913
- Testing
- Adenosine
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amphia Hospital
Coronary Artery Disease, Antiplatelet Therapy
Minimally Invasive Coronary Artery Bypass Supported by Cangrelor
The purpose of this study is to find out whether it is safe and practical to perform MIDCAB surgery (a minimally invasive heart bypass procedure) while patients receive a continuous cangrelor infusion during the operation.
- Conditions
- Coronary Artery Disease, Antiplatelet Therapy, Minimally Invasive Coronary Revascularization Surgery
- Trial name
- MINOTAUR (NCT07514962)
- Testing
- Cangrelor-guided MIDCAB surgery (for the prospective cases), Aspirin MIDCAB surgery (for the historical controls)
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Cardiocentro Ticino
Serratus Anterior Plane Block, Acute Pain
Combined SAPB in MICS
Minimally invasive cardiac surgery (MICS) has begun to be performed frequently in recent years. Compared to sternotomy, MISC reduces the risk of mediastinitis, leaves a more aesthetic scar, facilitates postoperative…
- Conditions
- Serratus Anterior Plane Block, Acute Pain, Postoperative Analgesia, Minimal Invasive Cardiac Surgery
- Trial name
- NCT06326320
- Testing
- Combined SAPB
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ankara City Hospital Bilkent
Cardiac Surgery
Erector Spinae Plane Block (ESP) vs Serratus Anterior Plane Block (SAP) for Loco-Regional Analgesia in Adult Patients Undergoing Minimally Invasive Cardiac Surgery Via Mini-Thoracotomy: Impact on Morphine Consumption, Pain Control, and Quality of Recovery
Optimization of postoperative analgesia and reduction of opioid consumption are key components of Enhanced Recovery After Surgery (ERAS) protocols in cardiac surgery.
- Trial name
- SAPESP (NCT07433114)
- Testing
- Serratus anterior plane block (SAP), Erector Spinae Plane block (ESP)
- Where
- Italy
- Volunteers
- 57 people
- Sponsor
- Azienda Socio Sanitaria Territoriale Ovest Milanese, Ospedale di Legnano
Coagulation Changes During Coronary Artery Bypass Grafting
Coagulation Profiles in Conventional and Minimal Invasive Extracorporeal Circulation
The aim of this study is to compare the effects of conventional and minimally invasive extracorporeal circulation (MiECC) techniques, which are routinely used in open-heart surgery, on coagulation parameters.
- Trial name
- NCT07844031
- Testing
- Conventional extracorporeal circulation, Minimally invasive extracorporeal circulation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Pain, Postoperative
Serratus Planus Block After Minimally Invasive Cardiac Surgery
Many patients receiving MICS (minimally invasive cardiac surgery) suffer from significant postsurgical pain. While systemic analgesic therapy has been proven to be insufficient in a great number of patients, significant unwanted…
- Trial name
- NCT06746272
- Testing
- Serratus Anterior Plane Block
- Where
- Austria
- Volunteers
- 66 people
- Sponsor
- Medical University of Vienna
Femoral Artery Injury, Aortic Valve Insufficiency
Short-term Clinical Follow-up of the Vascular Closure Device MANTATM in Minimally Invasive Cardiac Surgery
The percutaneous MANTA Vascular Closure Device is dedicated to the closure of large bore arteriotomies. It appears to be a safe and doable option for vascular access closure in patients undergoing transfemoral Transcatheter…
- Trial name
- MANTA-MICS (NCT04802200)
- Testing
- Data collect
- Where
- France
- Volunteers
- 204 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Cardiac Surgery
Ultra Fast-Track vs Fast-Track Protocols in Off-Pump and Minimally Invasive Valve Cardiac Surgery
Fast-track cardiac anesthesia (FTCA) has gained significant popularity over the past decades due to its potential to reduce healthcare costs and optimize the use of medical resources.
- Trial name
- Fast Track (NCT07518524)
- Testing
- Fast Track Cardiac Anesthesia (FTCA), Ultra Fast Track Cardiac Anesthesia (UFTCA)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Azienda Socio Sanitaria Territoriale Ovest Milanese, Ospedale di Legnano
Postoperative Pain, Minimal Invasive Cardiac Surgery
Serratus Anterior Plane Block and Serratus Anterior Plane Block + Continuous Wound Infiltration With Catheter
A total of 46 patients scheduled to undergo elective coronary artery bypass surgery via a minimally invasive technique will be included in the study.
- Trial name
- MICS (NCT06971432)
- Testing
- Group SAPB, Group SAPB + LIA
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ankara City Hospital Bilkent
Coronary Artery Bypass, Off-Pump, Minimally Invasive Cardiac Surgery
MInithoraCotomy vs Sternotomy for Multivessel Coronary Artery Bypass Grafting: A Partially Randomized Patient Preference Trial Assessing Quality of Life and Patency Outcomes
This trial will address essential questions of the efficacy and safety of MICS-CABG in addition to the quality of life and patency rate of the grafts.
- Trial name
- NCT04795193
- Testing
- Minimal invasive coronary surgery, Off-pump coronary artery bypass surgery
- Where
- China
- Volunteers
- 248 people
- Sponsor
- Peking University Third Hospital
Minimally Invasive Cardiac Surgery
Application of Bronchial Blocker in Minimally Invasive Cardiac Surgery
Both left single lung ventilation by left double lumen tube and bilateral ventilation with selective blockage of right middle lower lobe by bronchial blocker can provide suitable surgical field for minimally invasive cardiac…
- Trial name
- NCT03505242
- Testing
- bronchial blocker for BB group, double lumen tube for DLT group
- Volunteers
- 48 people
- Sponsor
- Shanghai Zhongshan Hospital
Heart Valve Diseases
Automated Fastener Device Versus Manually Tied Knot in MiAVR
The aim of the investigator's study was to evaluate the efficacy and the safety of the Cor-Knot device in isolated aortic valve replacement (AVR) by right anterior minithoracotomy (RAMT).
- Trial name
- NCT03664102
- Testing
- Cor Knot
- Volunteers
- 221 people
- Sponsor
- Centre Hospitalier La Chartreuse
Atrial Fibrillation
Surgical Ablation for Atrial Fibrillation
Minimally invasive approaches for surgical treatment have been advocated as a treatment option for stand-alone atrial fibrillation (AF).
- Trial name
- NCT04398979
- Testing
- Thoracoscopic Atrial fibrillation Ablation
- Volunteers
- 300 people
- Sponsor
- Nanjing Medical University
Cardiovascular Diseases
Groin Complications in Open Vs. Percutaneous Peripheral Cannulation in Minimally Invasive Cardiac Surgery
The aim of this randomized trial is to investigate the groin complications in open vs percutaneous peripheral cannulation for cardiopulmonary bypass in minimally invasive cardiac surgery
- Trial name
- ProGlide-II (NCT05598385)
- Testing
- Open cannulation, Percutaneous cannulation
- Sponsor
- Jessa Hospital
Aortic Valve Disease, Aortic Stenosis
EDWARDS INTUITY Elite Valve System
The purpose of this active, observational, open-label, non-randomized, post-market surveillance study is to confirm that EDWARDS INTUITY Elite reduces cross clamp time (XCT) in MIS setting when compared to published data with a…
- Trial name
- MISSION (NCT02907463)
- Where
- 23 sites in Austria, Denmark and 7 more
- Volunteers
- 280 people
- Sponsor
- Edwards Lifesciences
Minimally Invasive Cardiac Surgery
The Quality of Life and Patency Rate After Minimally Invasive Cardiac Surgery
This trial will address essential questions of the efficacy and safety of MICS-CABG in addition to the quality of life and patency rate of the grafts.
- Trial name
- NCT05104320
- Testing
- MICS-CABG, sternotomy CABG
- Volunteers
- 248 people
- Sponsor
- Peking University Third Hospital