Clinical trials: Mirogabalin
Bladder Pain Syndrome, Educational Behavioral Intervention
Mirogabalin Plus EBMP for IC/BPS
The goal of this clinical trial is to learn whether adding mirogabalin to educational-behavioral modification program (EBMP) improves symptoms and safety outcomes for adults living with interstitial cystitis/bladder pain syndrome…
- Conditions
- Bladder Pain Syndrome, Educational Behavioral Intervention, Urinary Urgency
- Trial name
- M-EBMP-IC/BPS (NCT07803393)
- Testing
- Behavioral: Educational and Behavioral Management Program (EBMP), Intervention
- Volunteers
- 200 people
- Sponsor
- Beijing Tiantan Hospital
Central Neuropathic Pain
Study of Mirogabalin for Central Neuropathic Pain
Investigate the efficacy and safety of mirogabalin in participants with central neuropathic pain in comparison to placebo
- Trial name
- NCT03901352
- Testing
- Mirogabalin
- Where
- 118 sites in Japan, South Korea and 1 more
- Volunteers
- 300 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Diabetic Peripheral Neuropathic Pain (DPNP)
Efficacy and Safety of Mirogabalin in Diabetic Peripheral Neuropathic Pain
The goal of this clinical trial is to learn if drug Mirogabalin works to treat diabetic peripheral neuropathic pain in adults. It will also learn about the safety of the drug Mirogabalin.
- Trial name
- NCT07451431
- Testing
- Mirogabalin, Pregabalin
- Where
- Bangladesh
- Volunteers
- 78 people
- Sponsor
- Bangladesh Medical University
Pain Associated With Fibromyalgia
Treatment of Pain Associated With Fibromyalgia
The main objective of this trial is to compare change in weekly average daily pain score (ADPS) from baseline to Week 13 in participants receiving either dose of DS-5565 versus placebo.
- Trial name
- NCT02187471
- Testing
- DS-5565, Pregabalin
- Where
- 154 sites in United States, Argentina and 12 more
- Volunteers
- 1,301 people
- Sponsor
- Daiichi Sankyo
Herpes Zoster, Mirogabalin
The Analgesic Efficacy and Safety of Mirogabalin in Patients With Herpes Zoster
Herpes zoster (HZ) is characterized by a painful dermatomal rash and significantly affects quality of life, with acute pain increasing the risk of postherpetic neuralgia.
- Conditions
- Herpes Zoster, Mirogabalin, Pain
- Trial name
- NCT07307170
- Testing
- Mirogabalin combined conventional therapy, Conventional therapy
- Where
- China
- Volunteers
- 750 people
- Sponsor
- Beijing Tiantan Hospital
Fibromyalgia
Safety Study of DS-5565 for Treatment of Fibromyalgia Pain in Subjects With Chronic Kidney Disease
DS-5565 (mirogabalin) is being studied as treatment for fibromyalgia (FM) pain. Because it is excreted through the kidneys, people who have reduced kidney function will not process the drug as well as with those with normal…
- Trial name
- NCT02496884
- Testing
- DS-5565
- Where
- 39 sites in United States, Bulgaria and 6 more
- Volunteers
- 56 people
- Sponsor
- Daiichi Sankyo
Breast Cancer, Post Operative Pain
Perioperative Mirogabalin for Pain Relief After Modified Radical Mastectomy
This study aims to evaluate whether perioperative mirogabalin can reduce postoperative pain and morphine consumption in female patients undergoing modified radical mastectomy for breast cancer.
- Trial name
- NCT07880821
- Testing
- Mirogabalin
- Volunteers
- 50 people
- Sponsor
- Cairo University
Diabetic Peripheral Neuropathic Pain, Post-herpetic Neuralgia
DS-5565 Phase III Study for Renal Impairment in Japanese Subjects
Investigate the safety and efficacy of DS-5565 in Japanese subjects with Diabetic Peripheral Neuropathic Pain (DPNP) with renal impairment or Post-Herpetic Neuralgia (PHN) with renal impairment.
- Trial name
- NCT02607280
- Testing
- DS-5565
- Where
- Japan
- Volunteers
- 35 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Diabetic Peripheral Neuropathic Pain
A Study to Evaluate the Safety and Effectiveness of Mirogabalin in Chinese Adult Patients With Diabetic Peripheral Neuropathic Pain (DPNP) in Real-world Clinical Practice Setting (ReMIssion Study)
This study will evaluate the safety and effectiveness of mirogabalin in adult patients with diabetic peripheral neuropathic pain (DPNP) in real-world clinical practice setting in China.
- Trial name
- NCT06812117
- Testing
- No Drug
- Where
- 43 sites in China
- Volunteers
- 721 people
- Sponsor
- Daiichi Sankyo
Diabetic Peripheral Neuropathy
Treatment of Neuropathic Pain Associated With Diabetic Peripheral Neuropathy
The purpose of this study is to evaluate the safety, tolerability and effectiveness of DS-5565 compared to placebo (inactive substance) and pregabalin in diabetic subjects with DPN.
- Trial name
- NCT01496365
- Testing
- DS-5565 tablet, pregabalin capsule
- Where
- 78 sites in United States
- Volunteers
- 452 people
- Sponsor
- Daiichi Sankyo
Pain, Diabetic Peripheral Neuropathy
Asian Phase 2 Study for Treatment of Pain Associated With Diabetic Peripheral Neuropathy
The purpose of this study is to investigate the effectiveness and safety of DS-5565, compared to placebo, in subjects with pain associated with diabetic peripheral neuropathy.
- Trial name
- NCT01504412
- Testing
- DS-5565, Pregabalin capsules
- Where
- 3 sites in Japan, South Korea and 1 more
- Volunteers
- 450 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Hip Osteoarthritis
Mirogabalin for Total Hip Arthroplasty
The purpose of this study is to confirm the analgesic effect of mirogabalin in patients undergoing unilateral hip arthroplasty.
- Trial name
- NCT05938088
- Testing
- Arm I (mirogabalin group)
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Gangnam Severance Hospital
Fibromyalgia, Pregabalin
The Efficacy and Safety of Pregabalin and Mirogabalin in Patients With Fibromyalgia
Fibromyalgia (FM) is a chronic pain syndrome characterized by widespread pain, fatigue, and emotional disorders. Its onset is related to factors such as central sensitization and imbalance of neurotransmitters.
- Conditions
- Fibromyalgia, Pregabalin, Mirogabalin, Pain
- Trial name
- NCT07157852
- Testing
- Mirogabalin, Pregabalin
- Where
- China
- Volunteers
- 674 people
- Sponsor
- Beijing Tiantan Hospital
Pain Associated With Fibromyalgia
Treatment of Pain Associated With Fibromyalgia
The main objective of this trial is to compare change in weekly average daily pain score (ADPS) from baseline to Week 13 in subjects receiving either dose of DS-5565 versus placebo.
- Trial name
- NCT02146430
- Testing
- DS-5565, Pregabalin
- Where
- 165 sites in United States, Canada and 9 more
- Volunteers
- 1,293 people
- Sponsor
- Daiichi Sankyo
Pain Associated With Fibromyalgia
An Open-Label Extension Study of DS-5565 for 52 Weeks in Pain Associated With Fibromyalgia
This is an open-label study of DS-5565 in subjects who either completed participation in a preceding Phase 3 study of DS-5565 in fibromyalgia (FM); i.e.
- Trial name
- NCT02234583
- Testing
- DS-5565
- Where
- 276 sites in United States, Australia and 27 more
- Volunteers
- 2,485 people
- Sponsor
- Daiichi Sankyo
Diabetic Peripheral Neuropathic Pain
A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled 14-week Study of DS-5565 in Chinese Patients With Diabetic Peripheral Neuropathic Pain
Investigate the efficacy and safety of mirogabalin in Chinese participants with diabetic peripheral neuropathic pain in comparison to placebo.
- Trial name
- NCT04094662
- Testing
- Mirogabalin
- Where
- 40 sites in China
- Volunteers
- 393 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Diabetic Peripheral Neuropathic Pain
DS-5565 Phase III Study for Diabetic Peripheral Neuropathic Pain
Investigate the efficacy and safety of DS-5565 in subjects with Diabetic Peripheral Neuropathic Pain (DPNP) in comparison to placebo
- Trial name
- NCT02318706
- Testing
- DS-5565
- Where
- Japan
- Volunteers
- 854 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
CIPN, CIPN - Chemotherapy-Induced Peripheral Neuropathy
Comparison of the Efficacy and Safety of Mirogabalin and Duloxetine in Chemotherapy-induced Peripheral Neuropathy in a Randomized Controlled Trial: a Quality of Life Study in Cancer Survivors
To conduct a two-arm, parallel, prospective, randomized controlled, open-label trial to compare the efficacy of the novel drug mirogabalin with the conventional treatment duloxetine in reducing pain associated with…
- Conditions
- CIPN, CIPN - Chemotherapy-Induced Peripheral Neuropathy, CIPN in Adjuvant Breast Cancer Patients, Duloxetine
- Trial name
- NCT06711978
- Testing
- Mirogabalin, Duloxetine
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Pusan National University Yangsan Hospital
Pain Postoperative, Osteoarthritis
Comparing Efficiency of Mirogabalin and Pregabalin in Primary TKA
The goal of this RCT is to compare efficacy between mirogabalin and pregabalin in pain reducing after unilateral primary total knee arthroplasty.
- Conditions
- Pain Postoperative, Osteoarthritis, Total Knee Arthroplasty
- Trial name
- NCT06328062
- Testing
- Mirogabalin, Pregabalin
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Thammasat University Hospital
Post-Herpetic Neuralgia
DS-5565 Phase III Study for Post-herpetic Neuralgia
Investigate the efficacy and safety of DS-5565 in subjects with Post-Herpetic Neuralgia (PHN) in comparison to placebo
- Trial name
- NCT02318719
- Testing
- DS-5565
- Where
- Japan
- Volunteers
- 765 people
- Sponsor
- Daiichi Sankyo Co., Ltd.