Clinical trials: Missing Teeth
Tooth Loss
Benefit of the Digital Workflow for Screw-retained Single Implant Restorations
The aim of this research project is emphasize the benefit of the digital workflow compared to conventional impressions and crown processing with standard la procedures.
- Trial name
- NCT03234868
- Testing
- Impression procedure, Crown manufacturing procedures
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Liege
Tooth Loss
Autotransplantation and Enamel Matrix Derivatives Case Series
The goal of this prospective case series is to compare the adjunctive use of enamel matrix derivatives in the treatment of tooth autotransplantation in terms of clinical attachment level.
- Trial name
- ATTCS (NCT06261255)
- Testing
- ATT + EMD
- Where
- 2 sites in Spain
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Dental Implants, Single Tooth Lost
5-year Follow up Study on the Comparative Performance of Two-piece Zirconia and Titanium Implants
A post-market, randomized-controlled, superiority clinical study to compare medium-term performance and safety of the Straumann PURE 2-piece Ceramic Implant with Straumann Bone Level Implant using a fully digital workflow.
- Conditions
- Dental Implants, Single Tooth Lost, Dental Implant Failed
- Trial name
- PostNCT0390817 (NCT05326880)
- Testing
- Ceramic Dental Implant, Titanium Dental Implant
- Where
- 2 sites in Germany, Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Missing Teeth, Dental Wear
REFRAME RPD Post-Market Clinical Study
To evaluate the change in patient Oral Health-related Quality of Life (OHRQoL) from wearing a cobalt chrome (CoCr) removable partial denture (RPD) to wearing the Solvay Dental 360TM polymer Removable Partial Denture (RPD) for 8…
- Trial name
- NCT03198520
- Testing
- Solvay Dental 360™
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Solvay Dental 360
Tooth Loss
Healing Dynamics in Human Extraction Sockets Grafted With Bio-Oss Collagen®
The purpose of this study is to clinically, radiographically and histologically evaluate the healing sequence of post-extraction sockets grafted with Bio-Oss Collagen® at 3, 6 and 9 months following tooth extraction in…
- Trial name
- NCT03659617
- Testing
- xenograft (BioOss Collagen)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Tooth Loss in the Anterior Maxilla, Alveolar Bone Loss* / Therapy
Beta-Tricalcium Phosphate Grafting of Peri-implant Jumping Gaps Greater Than 2 mm in Immediate Implants
This randomized controlled trial evaluated whether grafting the peri-implant "jumping gap" with injectable β-tricalcium phosphate (β-TCP) improves outcomes after immediate implant placement in sites where the horizontal gap…
- Trial name
- NCT07709676
- Testing
- Experimental: Test: beta-tricalcium phosphate grafting
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Minia University
Tooth Loss
Cold Plasma and Early Microbial Colonization of Healing Abutments
This prospective split-mouth clinical study will evaluate the effects of different plasma systems on the early microbiological colonization of implant healing abutments after implant surgery.
- Trial name
- NCT07548931
- Testing
- Control, Vacuum plasma, Argon jet plasma
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Missing Tooth
Clinical Assessment Of Inlay Retained Bridge Designs (Tub Shaped And Inlay Shaped) In Missing Posterior Teeth Cases.
The interest in partial coverage retainers such as inlays and onlays have increased drastically because these restorations are able to provide a more conservative option requiring minimal tissue removal thus preserving healthy…
- Trial name
- dentistry (NCT03715842)
- Testing
- Tub shaped design, Inlay shaped design
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Cairo University
Decay, Dental, Missing Teeth
Relationship Between Oral Findings and Salivary Factors in Sars-Cov-2 Patients
Two hundred individuals will be formed according to the study and control groups: Group-1: coronavirus 2 (Covid-19) (+) patients (n=100) and Group-2: Healthy individuals (in which the volunteers will be included due to group-1)…
- Conditions
- Decay, Dental, Missing Teeth, COVID-19, Cytokine Storm
- Trial name
- NCT05476848
- Testing
- ELISA test for Cytokines
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Ege University
Dental Implants, Tooth Loss
Immediate Load in Dental Implants Using Conventional Drilling and Piezoelectric Osteotomy on Aesthetic Zone.
Compare the survival rate of the implants placed using the ultrasonic technique and placed using conventional drilling, with an immediate load on the aesthetic zone.
- Trial name
- NCT04497571
- Testing
- Piezoelectric osteotomy., Conventional drilling
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Microbial Colonization, Missing Teeth
Effect of Crown Material on Gingival Microbial Colonization
Prior approval from SOD ethical committee has been received. All patients presenting to the General OPD of School of Dentistry, Islamabad will be screened.
- Trial name
- NCT07083102
- Testing
- Experimental
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Bone Loss, Alveolar, Tooth Loss
Tooth Autotransplantation and Bone Dimension Changes
Tooth autotransplantation is a treatment option to replace tooth with imposible prognosis. In several cases the receipt site has a reduced bone dimension.
- Conditions
- Bone Loss, Alveolar, Tooth Loss, Bone Atrophy, Alveolar
- Trial name
- NCT03927937
- Testing
- AUTOTRANSPLANTATION TOOTH
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Tooth Loss
Hard and Soft Tissue Maintenance Around Implants With a Sloped Configuration
This study is a controlled, randomized clinical trial over about 16-months (active phase). 40 patients in need of replacement of a single tooth with a minimal crestal bone width of 4 - 5mm and suitable for simultaneous GBR…
- Trial name
- NCT04712565
- Testing
- Astra Tech Implant System Profile EV, Astra Tech Implant System EV
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Tooth-loss, Edentulous Mouth
Complete Lower Dentures on 1 or 2 Implants
This study is a randomized clinical trial to compare patient satisfaction and prosthetic outcomes with lower dentures retained by one or two implants.
- Conditions
- Tooth-loss, Edentulous Mouth, Complete Denture, Complete Lower Denture
- Trial name
- NCT02117856
- Testing
- 1 implant placed surgically in the mandibular midline, 2 implants placed surgically in the mandibular canine sites, Soft reline (Coe Comfort) of the existing complete lower denture
- Where
- Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Posterior Mandible Missing Tooth and /or Teeth
Flapless Versus Flap Technique for Evaluation of Crestal Bone Loss and Osseointegration of Dental Implants
this study aimed to evaluate both clinically and radiographically the effect of flapless versus flap techniques on initial crestal bone loss and osseointegration of dental implants in lower posterior area.
- Trial name
- NCT07159529
- Testing
- flapless technique, flap technique, tissue punching
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tanta University
Periodontal Diseases, Tooth Loss
Effect of Periodontal Maintenance Therapy on Tooth Loss in Regular and Irregular Compliant Smokers and Non-Smokers: A Cohort Retrospective Analysis With a Follow-up Up to 40 Years
Periodontal diseases are infections cause by dental plaque (Socransky, 1970). Risk factors are present which modify the course of disease progression.
- Conditions
- Periodontal Diseases, Tooth Loss, Compliance, Smoking
- Trial name
- NCT04938089
- Testing
- Maintenance
- Where
- Lebanon
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Tooth Loss
Evaluation of a Lateral Window Technique Augmentation for Maxillary Sinus Using Ultrasound Activated Pins
Ultrasound activated pins have been used for the promotion of bone healing in combination with biodegradable membranes during bone grafting procedures.
- Trial name
- NCT02449707
- Testing
- Lateral Window Technique Augmentation for Maxillary Sinus, Ultrasound activated resorbable poly-D-L-lactide pins, Purus® Cancellous Allograft
- Where
- Saudi Arabia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Missing Teeth
Effect of Topical Application of Hyaluronic Acid on Stability of Immediate Loading Dental Implant in Posterior Maxilla
Effect of Topical Application of Hyaluronic Acid on Stability of Immediate Loading Dental Implant in Posterior Maxilla
- Trial name
- NCT05403099
- Testing
- Hyaluronic acid, conventional implant placement
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Space Maintenance, Tooth Loss / Rehabilitation
3D-Printed Versus Band-and-Loop Versus Denovo Space Maintainers in Primary Dentition.
Purpose of the Study When a child loses a "baby" molar early due to a cavity or injury, the surrounding teeth can shift into the empty space. This often blocks the permanent adult tooth from growing in correctly.
- Trial name
- NCT07613658
- Testing
- 3D-Printed Custom Space Maintainer, Conventional Band-and-Loop Space Maintainer, Denovo Chairside Space Maintainer
- Where
- Saudi Arabia
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Murad Alrashidi
Tooth Loss, Bone Graft; Complications
Patient-reported Outcome Measures After Implant Placement With Contour Augmentation Procedure
Maintaining the general health and well-being of patients is the main goal of dental therapy. However, tooth extraction is indicated when teeth cannot be maintained in a status compatible with health, adequate esthetics…
- Conditions
- Tooth Loss, Bone Graft; Complications, Patient Satisfaction, Patient Acceptance of Health Care
- Trial name
- NCT05890170
- Testing
- Patient Reported Outcomes Measures
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Bern