Clinical trials: Mobility
Somatosensory Function, Balance Control
Brain Stimulation for Foot-sole Sensation in Older Adults With Foot-sole Somatosensory Deficits
In older adults, diminished sensation of the legs and feet is highly prevalent and causes poor balance and reduced mobility. This type of sensation is not only dependent upon the receptors and nerves in the legs and feet, but…
- Conditions
- Somatosensory Function, Balance Control, Mobility
- Trial name
- BSFS (NCT06771531)
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hebrew SeniorLife
Hemiplegic Cerebral Palsy, Cerebral Palsy (CP)
Effects of Fun-Core (Child-Friendly Core Stabilization) Exercises on Balance and Functional Mobility in Children With Spastic Cerebral Palsy
A total of 54 children, aged between 6 and 12 years, diagnosed with hemiplegic cerebral palsy and not meeting the exclusion criteria, who registered at the outpatient clinics of the Department of Physical Medicine and…
- Conditions
- Hemiplegic Cerebral Palsy, Cerebral Palsy (CP), Core Stabilization, Exercise
- Trial name
- NCT07233824
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Istanbul University
Idiopathic Normal Pressure Hydrocephalus, Normal Pressure Hydrocephalus
Prediction of Response to Shunt Surgery in Normal Pressure Hydrocephalus Using Radscale and Lumbar Puncture
Idiopathic normal pressure hydrocephalus (iNPH) is a neurological disorder in older adults characterized by walking difficulties, cognitive decline, and urinary dysfunction.
- Trial name
- NCT07832877
- Volunteers
- 40 people
- Sponsor
- Assiut University
Menopause, Gait, Unsteady
Effects of Strength Training on the Gait and Pelvic Floor in Menopausal Women
The overall objective will be to observe whether a strength and balance training intervention produces significant changes in the analysis of double stance phase movement during gait, the analysis of coxofemoral, tibial and…
- Conditions
- Menopause, Gait, Unsteady, Pelvic Floor Disorders
- Trial name
- NCT07824947
- Testing
- Strength training
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Community-dwelling Older Adults, Neurocognitive Function of Elderly Patients
Modified Otago Exercise Program on Neurocognitive Level and Balance Parameters
This study examined the effect of an eight-week modified Otago Exercise Program on neurocognitive level and balance parameters in community-dwelling older adults.
- Conditions
- Community-dwelling Older Adults, Neurocognitive Function of Elderly Patients, Functional Mobility, Fall Prevention in Healthy Aging
- Trial name
- NCT07831174
- Testing
- Otago Exercise, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people
- Sponsor
- Alanya Alaaddin Keykubat University
Tooth Mobility, Injectable Platelet-rich Fibrin
Evaluating the Effect of Injectable Platelet-rich Fibrin on Accelerating Orthodontic Tooth Movement
One of the main goals of orthodontic treatment is the reduction of treatment time through faster tooth movement. The previous studies evaluating platelet-rich fibrin (PRF) and orthodontic tooth movement (OTM) are limited, which…
- Trial name
- NCT06302296
- Testing
- injectable form of PRF
- Where
- Syria
- Volunteers
- 14 people
- Sponsor
- Hama University
Periodontitis
Comparison of Replantation and Splinting Alone in Lower Anterior Teeth
Replantation is defined as the intentional extraction and repositioning of teeth that have lost their periodontal support. The aim of this study is to evaluate the clinical and radiographic follow-up results of planned…
- Trial name
- NCT07141680
- Testing
- Replantation, Splint
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Saglik Bilimleri Universitesi
Old Age, Mobility Limitation
RIC (Remote Ischemic Conditioning) in Older Individuals
The purpose of this study is to examine the feasibility and acceptability of a technique called remote ischemic conditioning (RIC) that aims to improve muscle strength, muscle mass, exercise tolerance, resilience (i.e.
- Conditions
- Old Age, Mobility Limitation, Debility
- Trial name
- NCT06476288
- Testing
- Low-intensity resistance exercise training, High-Dose Remote ischemic conditioning (RIC), Low-Dose Remote ischemic conditioning (RIC)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Duke University
Hyperparathyroidism, Parathyroid
Parathyroidectomy and Mobility Study
This study evaluates whether surgical removal of the parathyroid gland (parathyroidectomy) improves physical function and mobility in older adults with primary hyperparathyroidism (PHPT).
- Conditions
- Hyperparathyroidism, Parathyroid, Mobility
- Trial name
- NCT07103876
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Florida
Severe Mobility Impairment, Spinal Cord Injuries (SCI)
Effects of Virtual Walking on Chronic Pain and Psychological Distress for Individuals With Severe Mobility Impairment
This randomized controlled trial aims to: (1) examine the effects of virtual walking intervention on chronic pain (primary outcome), and on depression, stress, anxiety, and quality of life (secondary outcomes) compared with the…
- Conditions
- Severe Mobility Impairment, Spinal Cord Injuries (SCI), Poliomyelitis
- Trial name
- NCT07820618
- Testing
- Virtaul walking, Passive observing video
- Where
- Hong Kong
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Hearing Disability, Anxiety
Reduction of Anxiety Through Dual Treatment: Digital CBT & NBHWC Coaching
The purpose of this study is to see if a mobile-delivered mental health program called Toivoa-001, which combines digital cognitive behavioral therapy (CBT) with personal mental health coaching, can effectively reduce anxiety in…
- Conditions
- Hearing Disability, Anxiety, Mobility Disability
- Trial name
- NCT07140497
- Testing
- Toivoa-001 - A digital Cognitive Behavioral Therapy program combined with NBHWC-certified coaching.
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Toivoa Inc
Stroke, Spinal Cord Injuries
ZEPU-AI3 Lower Limb Feedback Robot Training Study
Lower limb motor dysfunction resulting from stroke, spinal cord injury, or other neurological disorders substantially limits mobility, independence, and quality of life.
- Conditions
- Stroke, Spinal Cord Injuries, Gait Disorders
- Trial name
- ZEPUAI3RCT (NCT07705906)
- Testing
- ZEPU-AI3 Lower Limb Feedback Training and Evaluation Robot, Conventional Rehabilitation
- Where
- Bangladesh
- Volunteers
- 32 people
- Sponsor
- Bangladesh Medical University
Hearing Disability, Depression
Reduction of Depression Through Dual Treatment: Digital CBT & NBHWC Coaching
The purpose of this study is to see if a mobile-delivered mental health program called Toivoa-002, which combines digital cognitive behavioral therapy (CBT) with personal coaching, can effectively reduce depression in adults with…
- Conditions
- Hearing Disability, Depression, Mobility Disability
- Trial name
- NCT07195292
- Testing
- Toivoa-002 - A digital Cognitive Behavioral Therapy program combined with NBHWC-certified coaching.
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Toivoa Inc
Functional Balance, Mobility Limitation
Adolescent Elite Athletes: Trunk Mobility, Lower Extremity Flexibility, and Functional Balance Across Sports
This cross-sectional observational study compared trunk mobility, hamstring flexibility, and dynamic functional balance performance among elite male adolescent athletes aged 15-17 years from different sports branches, including…
- Conditions
- Functional Balance, Mobility Limitation, Lower Extremity Problem
- Trial name
- TEF-BALANCE (NCT07395947)
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Idiopathic Normal Pressure Hydrocephalus (INPH)
Change in Cognition and Frailty After Shunt Surgery in Idiopathic Normal Pressure Hydrocephalus (iNPH)
The goal of this observational study is to describe changes in cognitive profile and frailty from pre shunt to one year after the shunt surgery and to identify clinical predictors of an improvement in terms of cognition and…
- Trial name
- NCT07642726
- Testing
- Ventriculoperitoneal shunt
- Where
- Norway
- Volunteers
- 276 people
- Sponsor
- Oslo University Hospital
Mobility Impairment
User Evaluation of Advanced Personalized Modular Pressure Relief Seating Cushion Systems
30 Veterans who are full-time wheelchair users will use personalized modular cushions for two weeks each. Personalized cushions will be created using a cushion fitting process the investigators have already developed and tested.
- Trial name
- Squishycushion (NCT03494127)
- Testing
- Use of GEL BALL FITTED MODULAR CUSHION, Use of SQUISHINS FITTED MODULAR CUSHION
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Stroke, Chronic Stroke
Reflex Excitability in Post-stroke Stiff-Knee Gait
The purpose of this study is to examine the reflex excitability of the rectus femoris in individuals with and without post-stroke Stiff-Knee gait.
- Conditions
- Stroke, Chronic Stroke, Gait, Hemiplegic, Gait, Spastic
- Trial name
- NCT04947865
- Testing
- Peripheral nerve stimulation, Commercial knee brace
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Limitation, Mobility, Older Adults
SuPA Mobility: Supporting Physical Activity for Mobility in Mobility-Limited Older Adults
The goal of this randomized controlled trial is to investigate the effectiveness of a health-coaching intervention to improve physical activity in older adults with limited mobility when compared to a control, health education…
- Trial name
- NCT05978336
- Testing
- Health Coaching Program, Health Education Program
- Where
- Canada
- Volunteers
- 290 people
- Sponsor
- University of British Columbia
Obesity & Overweight, Mobility Disability
Proof-of-Concept Study Evaluating Total Body Weight, Physical Function & Safety of Enobosarm in Patients Treated With GLP-1 Receptor Agonist, for Weight Loss
The primary objective of this study is to assess the effect of enobosarm on total body weight
- Conditions
- Obesity & Overweight, Mobility Disability, HOMA-IR
- Trial name
- PLATEAU (NCT07446998)
- Testing
- Enobosarm, Semaglutide (Wegovy) weekly injection
- Where
- 13 sites in United States
- Volunteers
- 239 people
- Sponsor
- Veru Inc.
PHYSIOLOGICAL PHENOMENA, Homeostasis
Truway Whole-Body Digital Twin and Physiologic Resilience Study (TRU-OMNIBODY)
TRU-OMNIBODY is a prospective observational study designed to develop and independently validate a research-only whole-body digital twin.
- Conditions
- PHYSIOLOGICAL PHENOMENA, Homeostasis, Physical Functional Performance, Cardiorespiratory Fitness
- Trial name
- TRU-OMNIBODY (NCT07805044)
- Testing
- Standardized Physiologic Resilience Challenge, Multimodal Whole-Body Physiologic Monitoring, Research-Only Whole-Body Digital Twin Analysis
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.