Clinical trials: Mobility Impairments
Cerebral Palsy
Exoskeleton-assisted Physiotherapy for Children With Mobility Impairments
Non-ambulatory children with cerebral palsy (CP) and similar childhood-onset neuromotor conditions face many challenges to fulsome participation in everyday life.
- Trial name
- NCT05463211
- Testing
- Trexo Plus Pediatric Exoskeleton
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Cognitive Impairment, High Fall Risk
Fall Prevention in Mild Cognitive Impairment
Falls represent the leading cause of hospitalization, nursing home admissions, disability and mortality for older adults with annual healthcare costs over $50 billion.
- Trial name
- NEUROFALL (NCT07507812)
- Testing
- Virtual Neurophysiological Rehabilitation
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- VA Office of Research and Development
Multiple Sclerosis
Exercise Balance Program for Fall Prevention in Multiple Sclerosis
Falls and balance impairments are common in individuals with multiple sclerosis (MS) and may negatively affect mobility, independence, confidence in daily activities, and quality of life, while increasing the risk of injury.
- Trial name
- NCT07331350
- Testing
- Combined Otago-Based and Game-Inspired Balance Training, Otago Exercise Program only
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- International Hellenic University
Bilateral Spastic Cerebral Palsy, Cerebral Palsy
Effect of Treadmill Gait Training Combined With Conventional Physiotherapy on Gait Performance and Functional Mobility in Children With Bilateral Spastic Cerebral Palsy: A Randomized Controlled Trial
Cerebral palsy is a neurological condition that affects movement, muscle control, and walking ability in children. Children with bilateral spastic cerebral palsy often experience increased muscle stiffness, difficulty with…
- Conditions
- Bilateral Spastic Cerebral Palsy, Cerebral Palsy, Spasticity Due to Cerebral Palsy, Gait Abnormality
- Trial name
- GAIT-CP (NCT07683338)
- Testing
- Treadmill Gait Training, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Syeda Khatoon e Jannat Welfare Foundation
Stroke, Ischemic, Stroke Hemorrhagic
Evaluation of the Effectiveness and Safety of Keeogo™ Dermoskeleton in Subjects With Mobility Impairments Due to Stroke
A multi-site, interventional, non-comparative, single-arm trial to evaluate the safety of the Keeogo™ Dermoskeleton in subjects with hemiparesis due to ischemic or hemorrhagic stroke.
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Stroke, Hemiparesis
- Trial name
- NCT03986320
- Testing
- Keeogo™ Dermoskeleton
- Where
- 4 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- B-Temia, Inc.
Spinal Cord Injury (SCI), Gait
Closed-Loop Vagus Nerve Stimulation (CLV) for Recovery of Gait After Spinal Cord Injury (SCI)
The purpose of this study is to evaluate the safety, feasibility, and preliminary effectiveness of the ReWire system, which delivers vagus nerve stimulation (VNS) paired with lower limb rehabilitation to improve gait in…
- Conditions
- Spinal Cord Injury (SCI), Gait, Reduced Physical Activity, Lower Limb Functions
- Trial name
- NCT07689227
- Testing
- CLV
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas at Dallas
Peripheral Artery Disease
BEETroot Juice to Reverse Functional Impairment in PAD
The BEET PAD Trial is a multi-centered double-blind randomized clinical trial designed to determine whether beetroot juice, compared to placebo, improves six-minute walk distance at four month follow-up in people with lower…
- Trial name
- BEET PAD (NCT05624125)
- Testing
- Beetroot juice
- Where
- 4 sites in United States
- Volunteers
- 210 people
- Sponsor
- Northwestern University
Mild Cognitive Impairment
Dual Task Training in Elderly Using the BioRescue
Mild cognitive impairment (MCI) is accompanied by gait and balance problems while dual tasking. During a 6 to 8 weeks training with the BioRescue (virtual reality), institutionalized elderly people with MCI will relearn dual…
- Trial name
- NCT02681354
- Testing
- Biorescue training
- Where
- 2 sites in Belgium
- Volunteers
- 21 people
- Sponsor
- Hasselt University
Mobility Limitation
Effect of Tele Rehabilitation in Breaking Barriers With Mobility Impairments in Rural Areas (RCT)
Tele-rehabilitation offers remote healthcare services via telecommunication technology to patients who face challenges in accessing traditional in-person rehabilitation.
- Trial name
- NCT06757972
- Testing
- Tele Rehab, Formal Rehab
- Where
- Pakistan
- Volunteers
- 92 people
- Sponsor
- Superior University
Frail Elderly, Cognitive Impairment
A Community Health Worker Program to Support Rural Older Adults
This study will investigate an intervention delivered by community health workers for older adults with signs of cognitive impairment, mobility loss, and depression in the rural primary care setting.
- Conditions
- Frail Elderly, Cognitive Impairment, Mobility Limitation, Depressive Symptoms
- Trial name
- NCT03843333
- Testing
- Tai Ji Quan: Moving for Better Balance, Behavioral Activation, Resource Navigation
- Where
- 3 sites in United States
- Volunteers
- 39 people
- Sponsor
- University of Vermont
Multiple Sclerosis
Physical Telerehabilitation in Multiple Sclerosis
The study aims to evaluate the efficacy of the MS HAT (Multiple Sclerosis Home Automated Telemanagement) System as an adjunct to the current standard of medical care for patients with MS (PwMS).
- Trial name
- NCT03230903
- Testing
- Home telerehabilitation, Usual Care
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Columbia University
Andropause
The Testosterone Trials in Older Men
The Testosterone Trials are a multi-center set of trials involving 12 clinical sites geographically distributed across the United States.
- Trial name
- NCT00799617
- Testing
- AndroGel® (testosterone gel)
- Where
- 12 sites in United States
- Volunteers
- 790 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Knee Osteoarthritis, Falls
Effects of Tele Rehabilitation vs Onsite Rehabilitation on Balance, Mobility, and Risk of Fall Among Geriatric Population With Knee Osteoarthritis
This randomized controlled trial aims to determine the effects of telerehabilitation versus onsite rehabilitation on balance, mobility, and risk of fall among geriatric patients with knee osteoarthritis (KOA).
- Conditions
- Knee Osteoarthritis, Falls, Balance Impairment, Mobility Limitation
- Trial name
- NCT07798973
- Testing
- Telerehabilitation, Onsite Rehabilitation
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Ibadat International University, Islamabad
Retinitis Pigmentosa (RP), Rod Cone Dystrophy
Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision Impairment
This pilot clinical trial evaluates whether non-invasive brain stimulation improves the orientation and mobility (O\&M) skills of individuals with constricted visual fields in both eyes. The study is composed of three visits.
- Conditions
- Retinitis Pigmentosa (RP), Rod Cone Dystrophy, Visually Impaired Persons, Peripheral Visual Field Defect of Both Eyes
- Trial name
- NCT07341763
- Testing
- Active hf-tRNS.
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Waterloo
Exercise, Gait
Rhythmically Entrained Exercise in Community-Dwelling Older Adults
Researchers at the University of North Carolina at Greensboro conduct a single-arm intervention trial to investigate the efficacy of a music-based group exercise program for community-dwelling older adults.
- Conditions
- Exercise, Gait, Cognitive Decline, Caregiver Burden
- Trial name
- REECO (NCT05462977)
- Testing
- Group exercise program
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Hearing Loss, Gait, Unsteady
Exercise to Improve Balance in Older Adults With Hearing Impairment - a Proof-of-concept Study
Hearing impairment is common in older adults, and recent research points to associations between hearing impairment and balance/mobility.
- Conditions
- Hearing Loss, Gait, Unsteady, Balance; Distorted, Old Age; Debility
- Trial name
- NCT04283279
- Testing
- Virtual reality exercise, Vestibular rehabilitation exercise, Control
- Volunteers
- 60 people
- Sponsor
- Western Norway University of Applied Sciences
Stroke, Ischemic, Stroke Hemorrhagic
Exploring Accessible Beauty for Individuals With Upper Extremity Deficits
The purpose of this study is to investigate the accessibility of beauty products for individuals with upper extremity disabilities.
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Stroke (CVA) or TIA, Stroke, Acute
- Trial name
- NCT05945784
- Testing
- Use of Rare Beauty makeup products
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Burn Injury, Physical Injury
STAT: Standard Therapy Plus Active Therapy
The objective of the study is to assess the efficacy of STAT, an activity-based therapy protocol compared to standard therapy (ST) to improve functional outcome and reduce disability in patients recovering from burn injury.
- Conditions
- Burn Injury, Physical Injury, Thermal Burn
- Trial name
- STAT (NCT04368117)
- Testing
- Physical Therapy
- Where
- 7 sites in United States
- Volunteers
- 166 people
- Sponsor
- American Burn Association
Disabled Persons
Mindfulness, Exercise, and Nutrition To Optimize Resilience (MENTOR)
The Mindfulness, Nutrition and Exercise to Optimize Resilience (MENTOR) program is offered through the National Center on Health, Physical Activity and Disability (NCHPAD).
- Trial name
- MENTOR (NCT06560619)
- Testing
- MENTOR
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Shirley Ryan AbilityLab
Somatosensory Function, Balance Control
Brain Stimulation for Foot-sole Sensation in Older Adults With Foot-sole Somatosensory Deficits
In older adults, diminished sensation of the legs and feet is highly prevalent and causes poor balance and reduced mobility. This type of sensation is not only dependent upon the receptors and nerves in the legs and feet, but…
- Conditions
- Somatosensory Function, Balance Control, Mobility
- Trial name
- BSFS (NCT06771531)
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hebrew SeniorLife