Clinical trials: Mobility Limitations, open to volunteers
Peripheral Artery Disease, Peripheral Vascular Disease
ENhancing Exercise With LIGHT to Improve Functioning in PAD
The ENLIGHTEN PAD Trial will collect preliminary data to test whether daily 660 nm light treatment of the lower extremities immediately before home-based walking exercise sessions improves six-minute walk distance at 4-month…
- Conditions
- Peripheral Artery Disease, Peripheral Vascular Disease, Aging, Walking, Difficulty
- Trial name
- ENLIGHTEN PAD (NCT06399900)
- Testing
- Far red light therapy, Home-based walking exercise
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Northwestern University
Gait Disorders
Effectiveness and Safety of Electrically Powered Orthopedic Exercise Device for Gait Disorders
Aging is a global trend, and consequently, the prevalence of age-related diseases is increasing. Gait disorders are common among the elderly and can result not only from various underlying conditions affecting gait but also from…
- Trial name
- NCT07147543
- Testing
- Electrically Powered Orthopedic Exercise Device
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Parkinson Disease, Freezing of Gait
Use of CereGate Therapy for Freezing of Gait in PD
A Multi-Center, Controlled Study to Evaluate Use of CereGate Therapy to Reduce Freezing of Gait in Participants Diagnosed with Parkinson's Disease.
- Conditions
- Parkinson Disease, Freezing of Gait, Deep Brain Stimulation
- Trial name
- NCT05292794
- Testing
- CereGate Software; BSN cDBS Programmer; BSN Burst Programmer
- Where
- 7 sites in United States
- Volunteers
- 41 people
- Sponsor
- CereGate Inc.
Endometriosis, Mobility Limitation
ENDOMETRIOSIS - MRI
Endometriosis is a frequent pathology with an estimated prevalence of 10% of women of childbearing age. There is no exact correspondence between the symptoms described by the patients and the severity of the lesions, which makes…
- Conditions
- Endometriosis, Mobility Limitation, Magnetic Resonance Imaging, Diagnosis
- Trial name
- ENDO-MRI (NCT05779462)
- Testing
- Dynamic MRI Sequence
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Lille
Peripheral Arterial Disease, Aging
SMART Exercise for PAD
Supervised exercise therapy (SET), consisting of treadmill exercise conducted three times weekly at a center while supervised by healthcare personnel, is first line therapy for people disabled by lower extremity peripheral artery…
- Conditions
- Peripheral Arterial Disease, Aging, Peripheral Vascular Diseases, Walking, Difficulty
- Trial name
- NCT06032065
- Testing
- Supervised Treadmill Exercise, Home-Based Exercise, Nitrate-rich beetroot Juice
- Where
- 3 sites in United States
- Volunteers
- 210 people
- Sponsor
- Northwestern University
Osteoarthritis, Osteoarthritis (OA) of the Knee
Feasibility of Choose to Move Replacement Ready
Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada.
- Conditions
- Osteoarthritis, Osteoarthritis (OA) of the Knee, Osteoarthritis, Hip, Total Knee Arthroplasty; Total Hip Arthroplasty
- Trial name
- CTM-RR (NCT07069179)
- Testing
- Choose to Move Replacement Ready
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Spinal Cord Injury, Spinal Cord Injury Subacute
Spinal Stimulation With Gait Training to Improve Lower Limbs Motor Recovery in Spinal Cord Injury
Spinal cord injury (SCI) often results in partial or complete loss of movement. In the subacute phase (< 6 months), the central nervous system shows increased potential for neuroplasticity, making it more responsive to…
- Conditions
- Spinal Cord Injury, Spinal Cord Injury Subacute, Locomotion, Gait Disorder, Sensorimotor
- Trial name
- CIMELocomotion (NCT07375745)
- Testing
- Protocol 2: Gait training combined with an effective tSCS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Telerehabilitation, COPD
Long-term Home-based Exercise for Patients With COPD: the COPDtoParis Project
This randomised controlled trial (RCT) aims to investigate the effect of long-term, interactive home-based cycle-exercise on patients with Chronic Obstructive Pulmonary Disease (COPD) after a COPD exacerbation requiring…
- Conditions
- Telerehabilitation, COPD, Quality of Life, Mobility Limitation
- Trial name
- COPDtoParis (NCT06235502)
- Testing
- Home-based cycle-exercise for COPD patients, Standard of Care
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Aalborg University Hospital
Stroke, Hemiparesis After Stroke
Effects of Intermittent Theta Burst Stimulation (iTBS) on Motor Recovery of Lower Extremity in Chronic Stroke Patients
This study aims to evaluate the effects and clinical feasibility of non-invasive brain stimulation protocols, specifically intermittent Theta Burst Stimulation, as part of rehabilitation interventions for motor recovery of lower…
- Conditions
- Stroke, Hemiparesis After Stroke, Chronic Stroke Patients, Hemiplegia
- Trial name
- NIMBLE (NCT07073235)
- Testing
- Intermittent Theta Burst Stimulation
- Where
- Sweden
- Volunteers
- 56 people
- Sponsor
- Danderyd Hospital
Falls Prevention
Walk On! National Council on Aging Innovation Lab
This is a multi-site, one-arm type-2 hybrid-effectiveness implementation trial. The goal of this clinical trial is to learn if the Walk On! program helps prevent falls in older adults who have trouble moving around or feel…
- Trial name
- Walk On! NCOA (NCT07368907)
- Testing
- Walk On! Program
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Wake Forest University Health Sciences
Peripheral Neuropathies, Peripheral Neuropathy Due to Chemotherapy
Balance4Mobility: Effects of Walkasins Use in Individuals With Peripheral Neuropathy and Balance Problems
The goal of this clinical trial is to is to test whether Walkasins can help people with peripheral neuropathy maintain their balance better.
- Conditions
- Peripheral Neuropathies, Peripheral Neuropathy Due to Chemotherapy, Peripheral Neuropathy With Type 2 Diabetes, Balance Control in Elderly
- Trial name
- NCT06959277
- Testing
- Walkasins, Fall Prevention Training
- Where
- 6 sites in United States
- Volunteers
- 200 people
- Sponsor
- RxFunction Inc.
Mobility Limitation, Physical Disability
Comparison of Two Park-Based Activities on Emotional Well-Being in Adults With Mobility Impairments
This study will examine the impact of a 10-week crossover urban park intervention on the emotional well-being of people with mobility impairments.
- Trial name
- NCT05975476
- Testing
- Physical Activity, Sensory Engagement
- Volunteers
- 10 people
- Sponsor
- University of Alabama at Birmingham
Retinitis Pigmentosa (RP), Rod Cone Dystrophy
Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision Impairment
This pilot clinical trial evaluates whether non-invasive brain stimulation improves the orientation and mobility (O\&M) skills of individuals with constricted visual fields in both eyes. The study is composed of three visits.
- Conditions
- Retinitis Pigmentosa (RP), Rod Cone Dystrophy, Visually Impaired Persons, Peripheral Visual Field Defect of Both Eyes
- Trial name
- NCT07341763
- Testing
- Active hf-tRNS.
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Waterloo
Fatigue, Walking, Difficulty
Neurophysiological Effects of Transcutaneous Electrical Nerve Stimulation in Persons With MS
Transcutaneous Electrical Nerve Stimulation (TENS) is a treatment that could potentially reduce walking problems and fatigue in persons with Multiple Sclerosis.
- Conditions
- Fatigue, Walking, Difficulty, Multiple Sclerosis
- Trial name
- NCT06432686
- Testing
- Transcutaneous Electrical Nerve Stimulation, Movement
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Abdominal Surgeries, Mobility Limitation
Validity and Reliability of the Arabic Version of De Morton Mobility Index After Abdominal Surgeries
PURPOSE: To determine validity and reliability of translated Arabic version of the De Morton Mobility index for mobility assessment in patients after abdominal surgeries.
- Conditions
- Abdominal Surgeries, Mobility Limitation, Mobility Difficulty, Abdominal Surgery Patients
- Trial name
- NCT06796218
- Where
- Egypt
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Cairo University
Peripheral Arterial Disease, Walking, Difficulty
Passive Stretching in Peripheral Arterial Disease Patients
Peripheral artery disease (PAD) leads to higher mortality rates and strains healthcare systems due to increased costs. It causes leg pain during walking due to reduced blood flow.
- Conditions
- Peripheral Arterial Disease, Walking, Difficulty, Inflammation
- Trial name
- NCT06420752
- Testing
- Calf Plantar flexion, Dietary nitrate
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Wisconsin, La Crosse
Parkinson Disease, Freezing of Gait
Remote Mental Practice for Freezing of Gait in Parkinson's Disease
This single-blind, randomized controlled trial investigates the effects of a remotely delivered intervention based on mental practice (MP) combined with physical practice (PP) on freezing of gait (FOG) severity in people with…
- Trial name
- NCT06957405
- Testing
- MPPG (Mental and Physical Practice Group), PPG (Physical Practice Group)
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo General Hospital
Vision, Low, Mobility Limitation
Evaluating Stairway Designs for Individuals With Vision Impairment
The goal of this study is to learn if contrast frequency on step tread-edges influences foot clearance measures, a marker of fall risk, in older adults with and without visual impairments.
- Trial name
- NCT07337317
- Testing
- Frequency of contrast marking on stair steps
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The University of Alabama in Huntsville
Amyotrophic Lateral Sclerosis (ALS)
Individualized Functional Imaging-Guided Repetitive Transcranial Magnetic Stimulation (rTMS) for Treating Postural Gait Disorders in Patients with Amyotrophic Lateral Sclerosis (ALS): a Randomized, Crossover, Controlled, Double-Blind Clinical Study
This study is a randomized, crossover, controlled, double-blind clinical trial. Patients (n=45) were randomly divided into Group A and Group B.
- Trial name
- iFIRST-ALS (NCT06819358)
- Testing
- Transcranial Magnetic Stimulation
- Volunteers
- 45 people
- Sponsor
- Peking University Third Hospital
Hip Fracture, Geriatrics
Clinical Efficacy of Exoskeleton Robot-Assisted Rehabilitation on Lower Limb Functional Recovery in Elderly Patients With Hip Fracture
With the intensification of population aging, hip fracture, as a common bone disease, is seeing an increasing incidence rate among the elderly population.
- Conditions
- Hip Fracture, Geriatrics, Lower Extremity Dysfunction, Postoperative Rehabilitation
- Trial name
- NCT07323147
- Testing
- Exoskeleton, Conventional rehabilitation program
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Hai bao