Clinical trials: Moderate Sedation, active
Pain Threshold, Conscious Sedation
Correlation Between Pain Threshold and Analgesic Consumption in Transvaginal Oocyte Aspiration Patients
Nowadays, in vitro fertilization (IVF) is an important component of modern infertility treatment. One of the critical stages of the IVF process is oocyte (egg) retrieval, which requires both anesthesia and analgesia; this…
- Conditions
- Pain Threshold, Conscious Sedation, Oocyte Retrieval
- Trial name
- NCT07262216
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Burcu ayvazoğlu
Aortic Stenosis
Conscious Sedation With Suprainguinal Facia Iliaca Block Versus Ilioinguinal Iliohypogastric Block for TAVI
the aim of the present study is to compare suprainguinal fascia iliaca block and ilioinguinal-iliohypogastric (II-IH) nerve block in improving the quality of conscious sedation, including reducing patients' requirements for…
- Trial name
- NCT06911463
- Testing
- suprainguinal fascia iliaca block group (SIFIB), iliohypogastric and ilioinguinal group (IL-IH), Local infiltration
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Ain Shams University
Postoperative Complications, Respiratory Depression
Comparison of Remimazolam and Propofol in Endoscopic Examinations and Treatments
This study aims to evaluate the efficacy and safety of Remimazolam, either used alone or in combination with Propofol, for moderate sedation anesthesia during endoscopic therapies or examinations.
- Conditions
- Postoperative Complications, Respiratory Depression, Postoperative Nausea, Vomiting
- Trial name
- Remimazolam (NCT06777758)
- Testing
- Remimazolam, Propofol
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Endoscopic Retrograde Cholangiopancreatography, Conscious Sedation Adverse Event
TEAS for Sedation During ERCP: A Multicenter Trial With Mechanistic Substudy
1. The goal of this clinical trial is to learn if transcutaneous electrical acupoint stimulation (TEAS), a non-invasive therapy that applies mild electrical current to specific points on the skin, can help patients undergoing…
- Conditions
- Endoscopic Retrograde Cholangiopancreatography, Conscious Sedation Adverse Event, Procedural Pain, Sedation-related Complications
- Trial name
- TEAS-ERCP-MC (NCT07440342)
- Testing
- TEAS + Conscious Sedation
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Beijing 302 Hospital
Aortic Valve Stenosis
RanDOmized stUdy Comparing Both Latest Generation Self-Expanding Valves and a Minimalist approaCH vs. Standard Of Care In transCathEter Aortic Valve Implantation
Open-label, 2 x 2 factorial, prospective, randomized, national, multicenter study to compare latest-generation self-expanding valves and a minimalist approach versus standard of care in transcatheter aortic valve implantation.
- Trial name
- DOUBLE-CHOICE (NCT05036018)
- Testing
- ACURATE neo2, minimalist approach, CoreValve Evolut Pro, Pro+ and FX
- Where
- 10 sites in Germany
- Volunteers
- 836 people
- Sponsor
- Leipzig Heart Science gGmbH
Lung Cancers, Peripheral Pulmonary Nodules
General Anesthesia vs Conscious Sedation for Radial Endobronchial Ultrasound
The endoscopic investigation of lung lesions is experiencing significant growth with the increasing number of lung cancer screening programs.
- Trial name
- RESSOURCE (NCT06950515)
- Testing
- Peripheral EBUS under Concious sedation, Peripheral EBUS under General Anesthesia
- Where
- Canada
- Volunteers
- 306 people
- Sponsor
- Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Atrial Fibrillation (AF), Catheter Ablation
Effects of Music During Atrial Fibrillation Ablation Under Conscious Sedation
I. Background Atrial fibrillation, a common type of arrhythmia, is often treated with radiofrequency catheter ablation, a minimally invasive procedure that helps restore a normal heart rhythm.
- Conditions
- Atrial Fibrillation (AF), Catheter Ablation, Pain Management
- Trial name
- NCT06953752
- Testing
- Music intervention, Control
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shaoxing People's Hospital
Airway Management
I-scoop vs. C-Mac D-Blade Videolaryngoscope for Airway Management Under Spontaneous Breathing and Analgosedation
The purpose of this clinical trial is to investigate whether the videolaryngoscope i-scoop makes airway management under spontaneous breathing and analgosedation more clinically practicable than the established standard device…
- Trial name
- OWN BREATH 2 (NCT07624162)
- Testing
- Airway management under spontaneous breathing with the i-scoop videolaryngoscope, Airway management under spontaneous breathing with the C-Mac D-Blade videolaryngoscope
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Hannover Medical School
Anxiety, Biliary and Pancreatic Diseases
Effect of Patient Anxiety Level Prior to Undergoing ERCP and Procedure Tolerability and Outcomes.
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a specialized procedure combining upper GI endoscopy and x-rays to treat hepatopancreaticobiliary diseases. Patient experiences after ERCP has been relatively understudied.
- Conditions
- Anxiety, Biliary and Pancreatic Diseases, ERCP
- Trial name
- NCT07699731
- Testing
- Not applicable- observational study
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Mandip Rai
Burn Injury, Hypoxia
Comparison of High Flow Nasal Oxygen and Nasal Cannula in Burn Patients Under Sedation
Burn-related pain is severe and often difficult to manage. Burn patients often require high doses of opioids and anxiolytics. Anesthetic agents used during sedation such as benzodiazepines, propofol and opioids can cause…
- Conditions
- Burn Injury, Hypoxia, Sedation
- Trial name
- NCT06756906
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ankara City Hospital Bilkent
Atrial Fibrillation (Paroxysmal)
Safety and Efficacy of Conscious Sedation Versus General Anesthesia in Pulsed-Field Ablation for Paroxysmal Atrial Fibrillation
The goal of this clinical trial is to compare the safety and efficacy of conscious sedation and general anesthesia in patients with paroxysmal atrial fibrillation undergoing their first pulsed-field ablation (PFA) procedure.
- Trial name
- SEDATE-PFA (NCT07541339)
- Testing
- conscious sedation, General Anesthesia (control group)
- Where
- China
- Volunteers
- 224 people
- Sponsor
- Beijing Anzhen Hospital
Atrial Fibrillation, Atrial Fibrillation, Paroxysmal or Persistent
Deep Sedation in Catheter Ablation of Atrial Fibrillation
The current practice of anesthesia for atrial fibrillation catheter ablation （CA） procedure is inconsistent, including general anesthesia, deep sedation, and conscious sedation.Due to the nature of deep sedation, it has been…
- Conditions
- Atrial Fibrillation, Atrial Fibrillation, Paroxysmal or Persistent, Deep Sedations, Conscious Sedation
- Trial name
- PRIORI-AF (NCT06836999)
- Testing
- deep sedation, Conscious sedation
- Where
- 16 sites in China
- Volunteers
- 1,334 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Procedural Sedation and Analgesia, Pediatric ALL
Study of the Efficacy of Moderate Sedation With Intra-NAsal Dexmedetomidine Monitored by EEG MOnitoring
This is a prospective, monocentric diagnostic study aiming to evaluate whether a sedation score obtained by a per-procedural electroencephalogram (EEG), the PSI score, could identify patients for whom a 2 μg/kg dose of DEX would…
- Trial name
- DINAMO (NCT06867289)
- Testing
- EEG
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Dental Caries, Tooth Extraction
Treating Children With Extensive Dental Needs
The goal of this qualitative study, using Grounded Theory, is to gain deeper knowledge about dentists' experiences from treating in particular young children with an extensive treatment need (mainly due to caries).
- Conditions
- Dental Caries, Tooth Extraction, Conscious Sedation, Attitude
- Trial name
- NCT06863103
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Malmö University
Heart Failure, Excessive Amount of Blood / Fluid Transfusion
Anesthesia for Catheter Aortic Valve ImplantATIOn Registry
In modern cardiac surgery and cardiology Transcatheter Aortic Valve Implantation (TAVI) is an emerging procedure for high-risk patients that are assumed to be otherwise inoperable.
- Conditions
- Heart Failure, Excessive Amount of Blood / Fluid Transfusion, Intraoperative Cardiac Arrest During Cardiac Surgery, Critical Incident
- Trial name
- AVIATOR (NCT01390675)
- Where
- Germany
- Volunteers
- 10,000 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Pain, Abortion
Diphenhydramine as an Adjunct to Moderate Sedation for Procedural First Trimester Abortions
This single center, double blind, randomized controlled trial will evaluate whether adding intravenous diphenhydramine to a standard moderate sedation regimen improves pain control during first trimester procedural abortion.
- Conditions
- Pain, Abortion, Anxiety
- Trial name
- NCT07542730
- Testing
- Diphenhydramine
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of Rochester
Child Behavior, Dental Caries in Children
Sedation Versus Protective Stabilization for Pediatric Dental Treatment
There is a lack of evidence on the effectiveness of moderate sedation in pediatric dentistry, compared to protective stabilization, which remains routinely used in the Brazilian context despite moral questions.
- Trial name
- NCT04119180
- Testing
- Ketamine 50 MG/ML, Midazolam Hcl 2Mg/Ml Syrup, Protective stabilization
- Where
- 2 sites in Brazil
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Atrial Fibrillation (AF)
Remimazolam-Fentanyl Mild Conscious Sedation Regimen in Pulsed-Field Ablation for Paroxysmal Atrial Fibrillation
This prospective single-arm study will evaluate whether mild conscious sedation using remimazolam with fentanyl is a feasible alternative to deeper sedation or general anaesthesia during FARAPULSETM pulsed-field ablation for…
- Trial name
- ReFeR-PFA (NCT07734194)
- Where
- Czechia
- Volunteers
- 20 people
- Sponsor
- Charles University, Czech Republic
Atrial Fibrillation
Conscious Sedation Study
The Conscious Sedation Single Arm Sub-Study is designed to evaluate the safety and performance of the CLAAS device implantation procedure using conscious sedation.
- Trial name
- CSS (NCT06049615)
- Testing
- CLAAS® System
- Volunteers
- 300 people
- Sponsor
- Conformal Medical, Inc
BPH (Benign Prostatic Hyperplasia), BPH
INTUPRO in the Treatment of Benign Prostatic Hyperplasia-Related Symptoms
The goal of this clinical trial is to determine whether INTUPRO can improve the quality of life in patients with Benign Prostate Hyperplasia (BPH).
- Conditions
- BPH (Benign Prostatic Hyperplasia), BPH, BPH With Other Lower Urinary Tract Symptoms
- Trial name
- NCT07381127
- Testing
- INTUPRO ionic fluid
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- inTumo Therapeutics, Inc.