Clinical trials: Modification
Thyroid Metabolism
The Reduced Thyroid Function of the Premature Newborn: Relation With Molecular Changes in the Placenta and Maternal Thyroid Hormone Status and Neurodevelopmental Implications
Transient hypothyroxinemia of prematurity (THOP) is a typical entity of the preterm infant, affecting the majority of preterm infants, born less than 30 weeks of gestational age.
- Trial name
- NCT01466023
- Where
- Belgium
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Motor Activity, Weight Loss
Effect of a Technology-Based Intervention on Weight Change Post-Bariatric Surgery
The primary aim of this study is to examine the effect of applying a minimal contact technology-based intervention (TECH) at 1-year post-bariatric surgery on weight change compared to Standard Care.
- Trial name
- NCT02867696
- Testing
- Standard Care, Technology-based Intervention (TECH)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Ovarian Cancer
Evaluation of Amino Acid Metabolism Changes in Ovarian Cancer
Ovarian cancer is associated with undernutrition in more than half of all cases. The current management of undernutrition-cachexia in cancer is not specific.
- Trial name
- AMINOCANCER (NCT06216496)
- Testing
- dynamic test for amino acid metabolism
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Gambling Disorder
Online Intervention to Promote Change and Help-Seeking in Young Adults With Gambling and Trading Problems
The goal of this study is to investigate if personalized online normative feedback (PONF) can increase intention to change and help-seeking behaviors in young adults with gambling or trading problems in Spain.
- Trial name
- NCT06681103
- Testing
- Personalized Normative Feedback
- Where
- Spain
- Volunteers
- 1,112 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Oropharyngeal Cancer
Modified Barium Swallow in Measuring Swallowing Function After Surgery in Patients With Oropharyngeal Cancer
This pilot clinical trial studies the modified barium swallow in measuring swallowing function after surgery in patients with oropharyngeal cancer who have undergone surgery.
- Trial name
- NCT01767961
- Testing
- diagnostic imaging, questionnaire administration, quality-of-life assessment
- Sponsor
- Wake Forest University Health Sciences
Orthognathic Surgical Procedures
Effects of Low Medial Ramus Osteotomy on Neurosensorial Recovery During Post-Operative Period
The aim of this study is to compare the post-operative neurosensorial disturbances of Hunsuck-Epkerr and "low and short medial osteotomy" modifications of sagittal split ramus osteotomy.
- Trial name
- NCT06662331
- Testing
- Bilateral Sagittal Split Osteotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Ali Törel Saygı
COPD
Change in Task-related Oxygen Uptake After EBV Treatment
Rationale: Bronchoscopic lung volume reduction using endobronchial valves (EBV) has emerged as a viable treatment option for eligible patients with severe emphysema.
- Trial name
- CROCODILE (NCT06702072)
- Testing
- Endobronchial valve treatment
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- University Medical Center Groningen
Diabetes Mellitus, Type 2, Obesity
Culturally Adapted Dietary Clinical Trial in PR
This project will determine whether a diet culturally adapted to adults in Puerto Rico can effectively decrease cardiometabolic risk factors.
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Hypertension, Dyslipidemias
- Trial name
- PRECISION (NCT05962372)
- Testing
- Culturally tailored food and diet advice, Standard healthy eating advice
- Where
- Puerto Rico
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
LPS, Mood Disorders
Resistance Exercise Plus Vinegar Ingestion on Biomarkers in Healthy Adults
Given its capacity to stimulate exercise-induced neuroplasticity at lower doses compared to aerobic exercise, resistance exercise has become the top-recommended rehabilitation approach for individuals with neurocognitive…
- Conditions
- LPS, Mood Disorders, Cognitive Change
- Trial name
- NCT06437405
- Testing
- Vinegar liquid, vinegar pill
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Obesity, Weight Loss
Bariatric Embolization of Arteries for the Treatment of Nonalcoholic Steatohepatitis
Obesity is an epidemic in the US. With progression of obesity, Nonalcoholic steatohepatitis (NASH) has been a growing public health issue.
- Conditions
- Obesity, Weight Loss, Body Weight, Nonalcoholic Steatohepatitis
- Trial name
- NCT02933554
- Testing
- Embospheres Microspheres
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Keith Pereira, MD:
Arthropathy, Incision, Surgical
Approach Modification for Total Knee Arthroplasty in Morbidly Obese Patients
The study provides a detailed description of a smaller incision with better visualization in total knee arthroplasty operations
- Conditions
- Arthropathy, Incision, Surgical, Obesity, Morbid
- Trial name
- NCT05840705
- Testing
- Small curved incision with apex lateral
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Breast Cancer, Weight Loss
Low Fat Versus Protein Sparing Diet for Weight Loss & Impact on Biomarkers Associated With Breast Cancer Risk
The primary specific aim of this study was to determine if overweight and obese premenopausal women can lose weight and if long term weight loss impacts biomarkers associated with breast cancer risk.
- Trial name
- LEAF (NCT01559194)
- Testing
- Low Fat Diet plus exercise, Low Carbohydrate diet + Exercise
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Fibromyalgia
Body Awareness Therapy and Biomarkers in Fibromyalgia
A randomized trial of Basic Body Awareness Therapy (BBAT) is applied in fibromyalgia patients as compared with a control intervention consisting of stretching.
- Trial name
- BATBF (NCT05555394)
- Testing
- Basic Body Awareness Therapy, Stretching Exercise
- Where
- 2 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Universitat de Lleida
Cognitive Change
Definition, Quantification, and Utility of Biomarkers of Repetitive Brain Injury in Predicting Concussion and Other Long-Term Injury Risks in Patients With Atrial Fibrillation (Concussion AF)
This is a prospective clinical study designed to evaluate biomarkers of brain injury and dementia incidence and moderate cognitive decline rates in moderate- to high-risk atrial fibrillation patients that undergo standard of care…
- Trial name
- Concussion AF (NCT03875131)
- Testing
- Biomarkers of Dementia and Cognitive Decline
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Intermountain Health Care, Inc.
Dental Implant, Diabetes
Stability and Crestal Bone Changes Around Implants Placed at Crestal Versus Subcrestal Level in Controlled Type Two Diabetic Patients
The objective of this study is to assess clinically the peri implant tissues, the radiological marginal bone loss and the stability around implants placed at the crestal versus the subcrestal level in type 2 controlled diabetic…
- Trial name
- NCT05125445
- Testing
- Implants placed at bone crest, Implants placed 1mm Subcrestally
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Hams Hamed Abdelrahman
Cognitive Change
Measuring Mindfulness Application
The purpose of the research study is to learn more about how ROTC cadets may engage with mindfulness training program content that is delivered through a smartphone or website application.
- Trial name
- NCT04589195
- Testing
- Mindfulness Training
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Miami
Multiple Sclerosis, Cognitive Dysfunction
HOBSCOTCH-MS-Efficacy Trial
The purpose of this study is to assess the ability of the home-based intervention, HOBSCOTCH-MS to improve the quality of life and cognitive function in Service Members, Veterans and civilians who have multiple sclerosis with…
- Conditions
- Multiple Sclerosis, Cognitive Dysfunction, Memory Disorders, Memory Impairment
- Trial name
- NCT06951919
- Testing
- Home Based Self- management and Cognitive Training Changes lives in Multiple Sclerosis (HOBSCOTCH-MS)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Cardiovascular Risk
Changing Lifestyle in Children
A lifestyle intervention aimed at improving exercise levels in primary school children.
- Trial name
- ALLChange (NCT01005186)
- Testing
- Eating habits, diet and exercise
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Dundee
Hypertension
Utilizing Telemedicine for Hypertension Treatment Lifestyle Modification in Central Harlem
The purpose of this study is to test the feasibility of creating a health education telemedicine curriculum that can be delivered by Weill Cornell Medicine faculty and medical students and NY-Presbyterian Hospital resident…
- Trial name
- NCT05062473
- Testing
- Lifestyle Modification Webinars Focused on Hypertension Control
- Where
- United States
- Sponsor
- Weill Medical College of Cornell University
Weight Loss, Reflux
Mechanism of Weight Loss After Endoscopic and Laparoscopic Sleeve Procedures
The purpose of this research study is to understand the mechanism of weight loss for weight loss procedures: that is Laparoscopic sleeve gastrectomy and Endoscopic sleeve Gastroplasty.
- Trial name
- NCT04006002
- Testing
- Metabolic and Hormonal profile
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Northwell Health
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