Clinical trials: Modification
Anxiety Symptoms, Depressive Symptoms
Project COPE-Spain (Coping Options for Parent Empowerment)
The goal of this study trial is to establish the preliminary clinical utility of the COPE program (Coping Options for Parent Empowerment) adapted for caregivers of adolescents in the Spanish context.
- Conditions
- Anxiety Symptoms, Depressive Symptoms, Parental Stress
- Trial name
- COPE-ES (NCT07006220)
- Testing
- COPE Program
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Universidad Nacional de Educación a Distancia
Youth Baseball Speed, Sprint Training, Weighted Vest, Change of Direction
Effects of Sprint Training With and Without Weighted Vests on Speed in Youth Baseball Players
Brief Summary We want to find out whether training with a weighted vest can help improve speed in U-14 baseball players. To do this, we will conduct a study with athletes like you, comparing performance before and after the…
- Trial name
- SWIFT-BASE (NCT07030296)
- Testing
- Sprint Training With Weighted Vest, Sprint Training Without Weighted Vest
- Where
- Colombia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of Vicosa
ICU Mortality (Survival Rate)
FOUR-Based Modification of ICU Severity Scores
The goal of this observational study is to evaluate whether the Full Outline of UnResponsiveness (FOUR) score can replace the Glasgow Coma Scale (GCS) as the neurologic component of established intensive care unit (ICU) severity…
- Trial name
- FOUR-ICU (NCT07832773)
- Where
- Iraq
- Volunteers
- 2,000 people
- Sponsor
- Al-Nahrain University
Obstructive Sleep Apnea, Obesity
Lifestyle Modification Using an App in OSA
This study aimed to investigate the effects of a mobile phone app linked to hospital electronic medical record (EMR) system on weight reduction and obstructive sleep apnea (OSA).
- Trial name
- NCT03189940
- Testing
- Life style modification by using and app with a wrist-worn activity tracker, Conventional Life style modification
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Spondyloarthritis, Spondylarthropathy
Assessment of SpondyloArthritis Society (ASAS) Classification and Diagnostic Criteria for Early Axial Spondyloarthritis (SpA)
Background: Existing criteria for AS/SpA such as mod. New York, ESSG, or Amor criteria for classification and/or diagnosis of spondyloarthritis have limitations when applied to early disease.
- Conditions
- Spondyloarthritis, Spondylarthropathy, Spondylitis, Ankylosing
- Trial name
- NCT00328068
- Where
- 35 sites in United States, Belgium and 18 more
- Volunteers
- 992 people
- Sponsor
- Charite University, Berlin, Germany
Infertility, Endometrial Peristalsis
Association Between Peri-Transfer Endometrial Peristalsis And Live Birth In Modified Natural Cycle Frozen Embryo Transfer: A Prospective Cohort Study
The uterus is a dynamic muscular organ that undergoes rhythmic, wave-like contractions known as endometrial peristalsis or endometrial waves.
- Conditions
- Infertility, Endometrial Peristalsis, Uterine Contraction, Endometrial Waves
- Trial name
- EPFE (NCT07358468)
- Testing
- Endometrial peristalsis and hormone measurements
- Where
- 2 sites in Vietnam
- Volunteers
- 384 people
- Sponsor
- Mỹ Đức Hospital
Critically Ill
Microcirculation in Spontaneous Breathing Trial
Weaning ventilator support in critically ill patients is crucial. Both delayed extubation and unexpected early reintubation are harmful to the patients.
- Trial name
- NCT04711590
- Testing
- Microcirculation examination
- Where
- Taiwan
- Volunteers
- 59 people
- Sponsor
- National Taiwan University Hospital
Obesity, Morbid
BAR-trial: Bioavailability of Ethanol Following Bariatric Surgery
The first-pass metabolism (FPM) is a barrier to the toxicity of ethanol. Changes to the size and function of the stomach may alter FPM.
- Trial name
- NCT01840020
- Testing
- Gastric bypass, gastric sleeve
- Where
- 2 sites in Norway
- Volunteers
- 33 people
- Sponsor
- Norwegian University of Science and Technology
Hypotension on Induction
Evaluation of the Changes of Pleth Variability Index During Preoxygenation for Predicting Hypotension
The aim of this study is to investigate whether the change in pleth variation index (PVI) according to preoxygenation can predict hypotension during anesthesia induction.
- Trial name
- NCT04991220
- Testing
- Preoxygenation
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Seoul National University Hospital
Brain Neoplasms
Radiotherapy - Cerebrovascular Reactivity (RT-CVR Study)
Brain tumours often have low oxygen levels, and that makes them more resistant to radiation therapy. If patients breathe the right mixture of oxygen during treatment, radiation may work better.
- Trial name
- NCT00297024
- Testing
- MRI
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University Health Network, Toronto
Obesity
SMART: A Social and Mobile Weight Control Program for Young Adults
The Social/Mobile Approach to Reduce Weight (SMART) study is a 24-month randomized control trial designed to evaluate the hypothesis that weight status at 24 months will be significantly better for the SMART intervention…
- Trial name
- SMART (NCT01200459)
- Testing
- Social/mobile weight loss promotion intervention.
- Where
- United States
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Obesity, Weight Loss
Lorcaserin in Obesity: Identification of CNS Targets Using fMRI
The purpose of this protocol is to investigate, using functional magnetic resonance imaging (fMRI), the effect of treatment with lorcaserin on centers of the brain that control appetite and food intake, as well as lorcaserin's…
- Trial name
- NCT02400359
- Testing
- Lorcaserin HCl
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Breast Cancer Female
Fertility Changes Due to Cancer: an Investigation of Meaning, Psychological Distress, and Psychologi
Establish the relationship between meaning and psychological distress in young women with breast cancer who experienced reproductive concerns due to cancer diagnosis and treatment and their partners.
- Trial name
- NCT05245162
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Acute Myeloid Leukemia
Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)
This phase II MyeloMATCH treatment trial studies how well ASTX727 and venetoclax plus enasidenib works compared to ASTX727 and venetoclax alone for the treatment of older patients with newly diagnosed acute myeloid leukemia (AML)…
- Trial name
- NCT06672146
- Testing
- Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy
- Where
- 138 sites in United States, Puerto Rico
- Volunteers
- 93 people
- Sponsor
- National Cancer Institute (NCI)
Type 2 Diabetes Mellitus (T2DM)
Helping Adults With Type 2 Diabetes Use Their Health Data for Healthy Diabetes Self-Management
Day-to-day self-management by adults with type 2 diabetes, including glucose monitoring, taking medications, and healthy habits, is essential to avoid diabetes complications, yet, despite the rapidly expanding availability of…
- Trial name
- MPowerHub (NCT06848361)
- Testing
- MPowerHub, Continuous Glucose Monitor (CGM), Activity Monitor
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Ann-Marie Rosland
Weight Loss, Mood
Effects of Lactobacillus Plantarum KABP-51 Probiotic on Body Composition, Microbiome and Mood in Healthy Overweight Adults
The objective of this study is to recruit 60 healthy moderately overweight subjects to participate in a research study investigating the effects of a specific probiotic strain (Lactobacillus plantarum KABP-51) on measures of…
- Trial name
- NCT06808061
- Testing
- Lactobacillus plantarum
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- 3 Waves Wellness
Pediatric Obesity
Exploring the Familial Reach of Adolescent Obesity Treatment
An observational study ancillary to the randomized clinical trial (RCT) TEENS+ (R01HD095910), a family-based lifestyle intervention, for adolescents with obesity, to determine: 1) if family-wide changes to the shared home…
- Trial name
- NCT05780970
- Testing
- No intervention
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Virginia Commonwealth University
Colorectal Cancer
Changes in Stem Cells of the Colon in Response to Increased Risk of Colorectal Cancer
Colorectal cancer is a common disease worldwide. Increasing evidence is demonstrating that colorectal cancers arise from 'cancer stem cells.' Stem cells in the colon reside at the bottom of thousands of microscopic crypts…
- Trial name
- NCT01075893
- Where
- 2 sites in United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Type 1 Diabetes Mellitus
B-Lymphocyte Immunotherapy in Islet Transplantation for Initial Islet Graft Failure
Type 1 diabetes is an autoimmune disease in which the insulin-producing pancreatic beta cells are destroyed, resulting in poor blood sugar control.
- Trial name
- NCT01049633
- Testing
- Allogeneic Pancreatic Islet Cells, Sirolimus, Basiliximab
- Where
- United States
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Multiple Myeloma
Early Response-adapted Intensification of Induction Chemotherapy in Patients With Newly Diagnosed Multiple Myeloma (MM)
In this study, the investigators will analyze the long-term outcomes of remission and survival, and identify those with primary resistant disease as more likely to benefit from CTD (thalidomide, cyclophosphamide, dexamethasone)…
- Trial name
- KMM-97 (NCT01114048)
- Testing
- Thalidomide, cyclophosphamide, dexamethasone, bortezomib
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Chonnam National University Hospital
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