Clinical trials: Modification
Intensive Care Medicine, ARDS
Change of Immune Cell of ARDS Patients：an Observational Study
To evaluate change of different immune cellsduring ARDS and its impact on prognosis.
- Trial name
- NCT02958748
- Testing
- taking blood sample
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Southeast University, China
Acute Promyelocytic Leukemia
Treatment of Newly Diagnosed Patients With Acute Promyelocytic Leukemia (PETHEMA LPA 2005)
Primary objectives To evaluate the efficacy and toxicity of a risk-adapted protocol that use idarubicin for induction and consolidation therapy in patients with APL.
- Trial name
- NCT00408278
- Testing
- ATRA, Idarubicina, Mitoxantrone
- Where
- 42 sites in Poland, Spain and 1 more
- Volunteers
- 300 people
- Sponsor
- PETHEMA Foundation
B-Cell Non-Hodgkin Lymphoma, Diffuse Large B-Cell Lymphoma
Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) Following Stem Cell Transplantation for the Treatment of Intermediate or High Grade B-cell Non-Hodgkin Lymphoma
This phase I trial studies the safety and side effects of cytomegalovirus (CMV) specific CD19-chimeric antigen receptor (CAR) T-cells along with the CMV-modified vaccinia Ankara (MVA) triplex vaccine following a stem cell…
- Conditions
- B-Cell Non-Hodgkin Lymphoma, Diffuse Large B-Cell Lymphoma, Mantle Cell Lymphoma, Recurrent B-Cell Non-Hodgkin Lymphoma
- Trial name
- NCT05432635
- Testing
- Anti-CD19-CAR CMV-specific T-lymphocytes, Autologous Hematopoietic Stem Cell Transplantation, Multi-peptide CMV-Modified Vaccinia Ankara Vaccine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- City of Hope Medical Center
Rhythm; Disorder
Audiovisuell Distraction Via 2d Videoglasses During Catheter Ablation Procedures in Cardiac Rhythm Disorders.
In this randomized controlled trial, amount of sedation exposure and patient satisfaction is evaluated in patients undergoing catheter ablation for rhythm disorders via an audiovisual distraction.
- Trial name
- NCT04873076
- Testing
- Audiovisual distraction using 2d video glasses from HappyMed GmbH
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- University Hospital, Essen
Psychotic Disorders
Effect of Antipsychotics on Appetite Regulation
The purpose of this study is to evaluate changes in appetite-regulating hormones, body composition (weight, body fat%), and hunger ratings in persons early in treatment with one of four atypical antipsychotic medications…
- Trial name
- ADAPT (NCT00903916)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of North Carolina, Chapel Hill
Cancer
Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer
RATIONALE: Cyproheptadine hydrochloride may prevent weight loss caused by cancer or cancer treatment. It is not yet known whether cyproheptadine is more effective than a placebo in preventing weight loss in young patients…
- Trial name
- NCT01132547
- Testing
- cyproheptadine hydrochloride
- Where
- 14 sites in United States
- Volunteers
- 22 people
- Sponsor
- University of South Florida
Climate Change Awareness
Climate Change Training for Primary Health Care Workers
Improving climate change awareness among primary care nurses is of great importance for the future of the health sector. Increasing this awareness enables primary care workers to combat environmental health problems more…
- Trial name
- NCT07809035
- Testing
- scenario-based climate change awareness training.
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Multiple Myeloma
CXCR4 Modified Anti-BCMA CAR T Cells for Multiple Myeloma
Multiple myeloma (MM) is an incurable plasma cell cancer that almost all patients eventually relapse despite advancement in treatment strategies.
- Trial name
- NCT04727008
- Testing
- CXCR4 modified anti-BCMA CAR T cells
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Sichuan University
Intestinal Flora
A Probiotic That Improve Intestinal Flora
Purpose: to verify the physiological properties of Lactobacillus rhamnosus LRa05. Bacterial count:100 billion Test Objective: to test and collect the changes of intestinal flora before and after the daily use of LRa05 product.
- Trial name
- NCT06103240
- Testing
- Lacticaseibacillus rhamnosus LRa05
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Childhood Obesity
Childhood Obesity- Characteristics and Treatment
The study is evaluating the effect of a 14-session cognitive behavioural treatment for childhood obesity. The treatment is family based and 49 families with children with obesity, aged 8-12, will be recruited.
- Trial name
- NCT00961740
- Testing
- Cognitive Behavioural Therapy, Waitlist condition
- Where
- Norway
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Hernia Incisional Ventral
Management Of Large Incisional Hernia, Double Mesh Modification Of Chevrel's Technique Versus On Lay Mesh Hernioplasty
comparison between two groups of large midline incisional hernia, the first group managed by double mesh modification of chevrel's technique the second one managed by conventional onlay mesh repair
- Trial name
- NCT04430816
- Testing
- double mesh modification of chevrel's technique, on lay mesh hernioplasty
- Where
- Egypt
- Volunteers
- 43 people
- Sponsor
- Zagazig University
Loss of Teeth Due to Extraction, Alveolar Bone Loss
Relate Tooth Alveolar Extraction Socket Anatomy to Alveolar Remodeling Rate
In patients that are going to be subjected to a tooth extraction in the anterior maxillary (from canine to canine) does the position of the intact alveolar socket related to maxillary basal bone interferes with the rate of…
- Conditions
- Loss of Teeth Due to Extraction, Alveolar Bone Loss, Bone Resorption
- Trial name
- NCT01963884
- Testing
- Tooth Extraction, Cone-Beam technology evaluation, Measure Alveolar Socket Remodeling
- Where
- Portugal
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Neurotrophic Ulcer, Neurotrophic Keratitis
OCT Evaluation of Neurotrophic Ulcer Following Treatment With Oxervate
Neurotrophic keratitis (NK) is a condition where the cornea, or clear outer covering of the eye, has reduced sensation due to a variety of reasons.
- Conditions
- Neurotrophic Ulcer, Neurotrophic Keratitis, Neurotrophic Corneal Ulcer, Neurotrophic Keratoconjunctivitis
- Trial name
- NCT04573647
- Testing
- Cenegermin-Bkbj 0.002% Ophthalmic Solution [OXERVATE]
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sight Medical Doctors PLLC
Gene Mutations, Pseudoxanthoma Elasticum
ADAPT Study: Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency
The purpose of this study (Study INZ701-304 [ADAPT]) is to assess the long-term safety of INZ-701 in patients with ENPP1 Deficiency or ABCC6 Deficiency who have received INZ-701 in an existing clinical study and choose to…
- Conditions
- Gene Mutations, Pseudoxanthoma Elasticum, Arterial Calcification, Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency
- Trial name
- NCT06462547
- Testing
- INZ-701
- Where
- 5 sites in United States, France and 2 more
- Volunteers
- 22 people
- Sponsor
- Inozyme Pharma
Diabetes Mellitus, Type 2, Neuropathy
Effects of Modified Otago Exercises in Individuals With Diabetic Neuropathy
The aim of the study is to investigate the effects of modified otago exercises on joint position sense, balance and physical fitness parameters in individuals with diabetic neuropathy.
- Trial name
- NCT05691738
- Testing
- Exercise Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Karamanoğlu Mehmetbey University
Pressure Ulcers
Pilot Study of Incidence and Change in Existing Pressure Ulcers: TC500 Bed Compared With Standard Beds
This pilot study will compare the incidence of pressure ulcers and the change in existing pressure ulcers for patients who are either placed on the new TC500 bed against those placed on the standard ICU bed in the Cardiovascular…
- Trial name
- NCT00771238
- Testing
- P500 Mattress
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Hill-Rom
Migraine
Longitudinal Changes of Brain Functional Connectivity in Migraine
The purpose of this study is to identify a core fMRI feature that determines migrainous brain and plastic fMRI features that changes with longitudinal courses of migraine.
- Trial name
- NCT03487978
- Testing
- resting-state functional MRI
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Acute Cerebral Ischemia
Field Randomization of Nerinetide (NA-1) Therapy in Early Responders
The purpose of this study is to determine whether nerinetide (NA-1) is effective in reducing global disability in patients with acute cerebral ischemia if administered early after symptom onset.
- Trial name
- FRONTIER (NCT02315443)
- Testing
- Nerinetide (NA-1)
- Where
- 4 sites in Canada
- Volunteers
- 532 people
- Sponsor
- NoNO Inc.
Nonspecific Shoulder Pain, Shoulder Pain Syndrome
Effect of US-Guided PNM in CrossFit With Nonspecific Shoulder Pain
CrossFit is a high-intensity physical training program that combines exercises from various disciplines, such as weightlifting, track and field, running, and gymnastics.
- Trial name
- NCT06958276
- Testing
- Ultrasound Guided Percutaneous Neuromodulation. Frequency of 10 Hz, Ultrasound Guided Percutaneous Neuromodulación. Frequency of 1 Hz
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Universidad de Zaragoza
Hypothermia, Shivering
Effect Of Acupressure On Hypothermıa And Shıverıng After Cesarean Sectıon
This research was planned to determine the effect of acupressure on hypothermia and shivering after cesarean section. H01: There is no difference in hypothermia findings between women who received acupressure and women in the…
- Conditions
- Hypothermia, Shivering, Postoperative Hypothermia, Postoperative Shivering
- Trial name
- NCT07864376
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.