Clinical trials: Modification
Obesity
Can Genetic Markers Predict Weight Loss After Gastric By-pass Surgery
There is a variability in weight loss after gastric bypass surgery for obesity despite a standardised surgical procedure. This study aims to investigate if genetic markers can predict outcome after gastric by-pass surgery in…
- Trial name
- NCT01736384
- Testing
- Gastric bypass or cholecystectomy
- Where
- 3 sites in Sweden
- Volunteers
- 2,000 people
- Sponsor
- Karolinska Institutet
Endometriosis
The Role of a Mediterranean Diet in Patients With Endometriosis: a Feasibility Trial
This study aims to test if making changes to diet can affect the pelvic pain associated with endometriosis. One group will follow a Mediterranean diet for 12 weeks while the control group will continue with their current diet.
- Trial name
- MDIE (NCT05411549)
- Testing
- Diet Modification to Adopt Mediterranean Diet
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- McMaster University
Rotator Cuff Tears
A New Modified Suture Bridge Technique
We aimed to introduce a new modified suture bridge technique and report the clinical outcomes and radiological assessments of modified suture bridge technique for medium rotator cuff tears.
- Trial name
- NCT04825249
- Testing
- traditional suture bridge technique, modified suture bridge technique
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Weight Loss, Food Habits
School Intervention With Daily Physical Activity and Healthy Food for Students With an Intellectual Disability.
A whole of school intervention with daily physical activity and healthy food for students with intellectual disabilities. The aim is to provide plenty of concrete examples of healthy life style choices and using school personnel…
- Conditions
- Weight Loss, Food Habits, Mental Retardation
- Trial name
- NCT01291238
- Testing
- Healthier, Smarter, Happier
- Where
- Sweden
- Volunteers
- 145 people
- Sponsor
- Karolinska Institutet
Optic Glioma, Pediatric Brain Tumor, Optic Nerve Glioma
Modified CV Regimen in Optic Pathway Glioma
Optic pathway glioma (OPG) can result in visual deterioration. Symptomatic patients often report deficits in visual acuity (VA), visual field, visual-evoked potentials (VEPs), strabismus, proptosis, disc swelling, and other…
- Trial name
- NCT05278715
- Testing
- Carboplatin, Vincristine, Recombinant human endostatin
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Beijing Sanbo Brain Hospital
Muscle Mass, Protein Intake
Distribution of Nutrient Derived Amino Acids
The project examines over several days how the distribution pattern of dietary protein stimulate and affect the protein turnover of important proteins in the aging perspective, such as skeletal muscle proteins.
- Conditions
- Muscle Mass, Protein Intake, Diet Modification, Protein Synthesis
- Trial name
- NCT03870425
- Testing
- Distribution pattern of dietary proteins (minced meat)
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Lung Cancer, Lung Cancer Metastatic
ANET Electrosurgery Applicator Pilot Evaluation Study
Evaluate the preliminary safety and performance of the Electrosurgery Applicator (ANET device) during and after bronchoscopic ablation of a target pulmonary nodule/tumor.
- Trial name
- NCT03400748
- Testing
- RF Ablation
- Where
- 4 sites in United States, Canada
- Volunteers
- 6 people
- Sponsor
- Olympus Corporation of the Americas
Autistic Disorder
Motor Learning and Brain Changes in Autism
The purpose of this pilot study is to determine whether a video-game based motor training can affect postural stability, daily living skills, autism symptoms, and white matter microstructure of the corticospinal tract in…
- Trial name
- NCT02358317
- Testing
- Video Game Motor Training, Sedentary Video Game Training
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Chronic Granulomatous Disease
Modified Stem Cell Transplantation Procedure for Treating Chronic Granulomatous Disease
This study will investigate the safety and effectiveness of a new stem cell transplant procedure for treating chronic granulomatous disease (CGD) in patients with active infection.
- Trial name
- NCT00006417
- Testing
- Stem cell transplantation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Achilles Tendinopathy (AT)
Change in ATOR Screening Test Scores Over 12 Weeks
Achilles tendinopathy (AT) is one of the most common overuse injuries in runners, with an estimated incidence ranging from 0.6% to 18.5% of all running-related injuries, reaching up to 52% in elite runners.
- Trial name
- ATOR (NCT07497217)
- Testing
- Alfredson Exercise Program + Health Education + Analytical Stretching, Alfredson Exercise Program + Health Education
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Zaragoza
Non Small Cell Lung Cancer, Non Small Cell Lung Cancer Metastatic
Immunological Profile Changes In Patients With Advanced Non-Small Cell Lung Cancer
This is a blood collection study being conducted to better understand and describe the immunological blood profile changes in patients with advanced non small cell lung cancer undergoing treatment with checkpoint inhibitor…
- Conditions
- Non Small Cell Lung Cancer, Non Small Cell Lung Cancer Metastatic, Healthy
- Trial name
- NCT04187768
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Indiana University
Health Prevention
Work Place Health Promotion: a Change Project
The purpose of this study is to determine if intelligent physical exercise training can increase the productivity of office workers in Denmark. Effects of intervention is measured after 1 and 2 years.
- Trial name
- HEALTHCHANGE (NCT01366950)
- Testing
- Intelligent physical activity
- Where
- 5 sites in Denmark
- Volunteers
- 406 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Malaria, Fever
Cluster Randomised Trial of Malaria RDTs Used by CHWs in Afghanistan
Malaria is a common, but decreasing, cause of fever in endemic areas. The use of rapid diagnostic tests could improve treatment of malaria at the local community level. Deployment of these tests is, however, a considerable cost.
- Conditions
- Malaria, Fever, Acute Febrile Illness, Pneumonia
- Trial name
- NCT01403350
- Testing
- Malaria Rapid Diagnostic test
- Where
- 3 sites in Afghanistan
- Volunteers
- 2,421 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Atrial Fibrillation
Antiorbital Calcium in Chronic Conditions
The purpose of this study is to determine the mechanistic effects of an ionic calcium supplement in adults with atrial fibrillation, osteoarthritis, and hypertension.
- Trial name
- AntiAFib (NCT05302713)
- Testing
- Ionic Calcium, Calcium Carbonate
- Where
- United States
- Sponsor
- National University of Natural Medicine
Pre-diabetes
A Community-based Weight Loss Programme for Chinese Overweight Adults With Pre-diabetes
Type 2 diabetes (T2DM) is a serious chronic condition and one of the world's fastest growing health problems. The onset of T2DM is gradual, with most individuals progressing through a state of pre-diabetes.
- Trial name
- NCT03609697
- Testing
- group-based lifestyle intervention, Minimal intervention (SMS intervention)
- Where
- Hong Kong
- Volunteers
- 180 people
- Sponsor
- The University of Hong Kong
Digital Technology, Dental
Accuracy of Tooth Modified Scan Bodies as a Novel Technique
The clinical performance of a novel scan body Tooth Modified Scan Body (TMSB) in the degree of trueness of IOS impression for full arch cases. I
- Trial name
- NCT06177782
- Testing
- Tooth modified scan bodies, Conventional scan bodies
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Diabetes Mellitus, Obesity
A Low-Carbohydrate, Ketogenic Diet Versus Orlistat for Weight Loss
This study compares two types of diet interventions: a low carbohydrate ketogenic diet (Atkins) and a low-fat diet combined with a medication (Orlistat).
- Trial name
- NCT00108524
- Testing
- Low carbohydrate ketogenic diet, Orlistat, Low-fat diet
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Tibialis Posterior Dysfunction, Emg
Pilot Study to Develop Protocols for Recording Tibialis Posterior EMG
This is an observational pilot study to allow us to create a normal database of muscle function of one of the muscles in the back of the leg (tibialis posterior).
- Trial name
- NCT06131359
- Testing
- Fine wire EMG and Force Frame muscle strength testing
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Prostate Cancer
Exercise-induced Steroid Changes in Active Surveillance for Prostate Cancer
The purpose of this research study is to understand how a short session of a home-based bodyweight high-intensity interval training (HIIT) affects steroid hormone levels in men on active surveillance for low-grade prostate cancer.
- Trial name
- ESCAPE (NCT07518888)
- Testing
- High-Intensity Interval Training (HIIT) Exercise
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Miami
Weight Gain
Growth and Safety Clinical Trial on a New Infant Formula
The aim of this study is to assess age-appropriate growth of healthy infants fed a new infant formula. In this randomized, controlled trial, healthy, term, formula-fed infants will be randomized to one of two infant formulas: a…
- Trial name
- NCT05508750
- Testing
- New Infant Formula, Commercial Infant Formula
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Jovie USA, LLC
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