Clinical trials: Modification
Burns, Pain, Burning
Effects of Applying Streaming Media on Reducing Pain in Patient With Second-degree Burn During Changing Dressing
During the acute phase of burn injuries, the focus for patients is primarily on wound pain and infection care. Patients often describe the pain during dressing changes as a sharp, stabbing sensation.
- Conditions
- Burns, Pain, Burning, Anxiety
- Trial name
- NCT06076031
- Testing
- Streaming Media
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chiayi Christian Hospital
Right Ventricular Dysfunction
Right Ventricular Function Changes After CIED Implantation: The RIGHT-CIED Study
This study aims to understand how the right side of the heart changes in people who receive an implantable cardiac electronic device (CIED), such as a pacemaker, ICD, or CRT device.
- Trial name
- RIGHT-CIED (NCT07272395)
- Testing
- Multimodal Right Ventricular Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University - Cerrahpasa
Weight Gain
Exenatide for the Treatment of Weight Gain Associated With Olanzapine in Obese Adults
The purpose of this research study is to test the safety and efficacy (how well it works) of exenatide as a treatment for weight gain associated with olanzapine in obese adults with Bipolar Disorder, Major Depressive Disorder…
- Trial name
- NCT00845507
- Testing
- Exenatide
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Cincinnati
ARDS, Human, Extracorporeal Membrane Oxygenation Complication
Effects of Induced Moderate Hypothermia on ARDS Patients Under Venovenous ExtraCorporeal Membrane Oxygenation
Acute respiratory distress syndrome (ARDS) is a lesional pulmonary edema that occurs as a result of direct or indirect lung injury.
- Conditions
- ARDS, Human, Extracorporeal Membrane Oxygenation Complication, Hypothermia
- Trial name
- HypoLungECMO (NCT05306392)
- Testing
- Moderate Hypothermia, Normothermia
- Volunteers
- 30 people
- Sponsor
- Central Hospital, Nancy, France
Fall Risk in Middle-Aged and Older Adults
Short-term Changes in Postural Sway, Gait, and fNIRS-derived Cortical Metrics After a 4-week AI-assisted Exercise Program: a Single-arm Pre-post Study
This single-arm pre-post study will enroll 50 participants aged 52-65 years who will undergo a 4-week AI-assisted exercise intervention.
- Trial name
- NCT07876011
- Testing
- AI-assited exercise
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Breast Cancer Female
Does Type of Anesthesia Influence Inflammation Change After Breast Surgery?
The Neutrophil to Lymphocyte Ratio (NLR) is a frequently used biomarker of the systemic inflammatory response and is considered one of the most sensitive markers of inflammation.
- Trial name
- NCT04172220
- Testing
- Midazolam, PECS, Opioid-free general anesthesia
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- Centro di Riferimento Oncologico - Aviano
Liver Failure
Evaluation of HDL Subfraction Changes and HDL-Associated Enzymes in Liver Failure Patients and Healthy Donors
This study aimed to determine high-density lipoprotein (HDL) subfraction profile and HDL-associated enzyme changes in liver failure patients and healthy donors.
- Trial name
- NCT05958420
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Akdeniz University
Hypothermia; Anesthesia, Hypothermia, Newborn
Perioperative Warming Measures in Cesarean Delivery
The purpose of this study is to evaluate the best method for keeping patients warm during cesarean deliveries and the effect of temperature change on the patient and baby
- Conditions
- Hypothermia; Anesthesia, Hypothermia, Newborn, Hypothermia, Sequela
- Trial name
- NCT05015582
- Testing
- Pre op upper body forced air warming (32˚C), Pre op lower body forced air warming (32˚C), Pre op fluids (45˚C)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- The University of Texas Health Science Center, Houston
Papillomavirus Vaccines, Papillomavirus Infections
Changes in the Prevalence of Oncogenic HPV Types
In Japan, nationwide prophylactic HPV vaccination was implemented in 2010; a bivalent vaccine was given from 2010 to 2012, and a quadrivalent vaccine from 2012. However, the program essentially ceased in June 2013. 1.
- Trial name
- NCT04671823
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Kanazawa Medical University
Pulmonary Disease, Chronic Obstructive
Greek NIS Spiolto ELLACTO
Open-label observational study: including COPD patients receiving treatment with Spiolto® Respimat® for approximately 6 weeks, which is the average time between two medical consultations
- Trial name
- NCT03419962
- Testing
- MaxSpiolto® Respimat® 160 Characters...
- Where
- 15 sites in Greece
- Volunteers
- 1,360 people
- Sponsor
- Boehringer Ingelheim
Low Back Pain, Recurrent
Exercise Therapy for Recurrent Low Back Pain: Unraveling the Puzzle of Peripheral Muscle and Central Brain Changes (B670201420984)
Exercise therapy has been shown to be effective in decreasing pain and improving function for patients with recurrent low back pain (LBP).
- Trial name
- ExTraS (NCT05706103)
- Testing
- Specific skilled motor training, General extension training
- Where
- Belgium
- Volunteers
- 62 people
- Sponsor
- University Ghent
Ulcerative Colitis
Effects of Eicosapentaenoic Acid on Subjects at High Risk for Colorectal Cancer
The aim of this study is to test Eicosapentaenoic acid's effects on markers relevant to colorectal carcinogenesis, RNA and DNA profiles, and the possibility that Eicosapentaenoic Acid treatment might be associated with changes of…
- Trial name
- EPAUC (NCT02069561)
- Testing
- Eicosapentaenoic Acid
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Post-COVID-19
Changes in Selected Function- and Participation-related Characteristics in Post-COVID Patients Following Pneumological Phase II Rehabilitation
The aim of this project is to provide insight into the relatively new group of post-COVID patients. On the basis of data collected in routine practice, function- and participation-related patient characteristics of post-COVID…
- Trial name
- NCT05496842
- Testing
- Multimodal pulmonary rehabilitation
- Where
- Austria
- Volunteers
- 779 people
- Sponsor
- Pensionsversicherungsanstalt
Lipodystrophy, Diabetes
Low Energy Diet and Familial Partial Lipodystrophy
To evaluate the therapeutic efficacy and metabolic impact of a low energy diet (LED) in people with familial partial lipodystrophy and diabetes.
- Conditions
- Lipodystrophy, Diabetes, Diet Modification
- Trial name
- NCT03900286
- Testing
- Total Dietary Replacement
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Vascular Parkinsonism
18F-DTBZ PET and Multi-modal MRI in the Patients With Vascular Parkinsonism
Forty patients with clinically diagnosed VP and 20 healthy subjects will be enrolled in the study. Each evaluable subject involved in this study must fulfill all the inclusion and exclusion criteria and each subject will have 3…
- Trial name
- NCT02195154
- Testing
- 18F-DTBZ
- Where
- Taiwan
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Heart; Surgery, Heart, Functional Disturbance as Result
The Role of Modified Ultrafiltration Following Open Heart Surgery
This study aims to investigate the effect of combining conventional ultrafiltration and modified ultrafiltration compared to conventional ultrafiltration alone in patients who underwent open heart surgery.
- Trial name
- NCT06085066
- Testing
- Conventional Ultrafiltration alone on Cardiopulmonary bypass, Conventional Ultrafiltration followed by Modified Ultrafitration on Cardiopulmonary bypass
- Where
- Indonesia
- Volunteers
- 38 people
- Sponsor
- Universitas Indonesia
Brain Ischemia
Mild Hypothermia in Acute Ischemic Stroke
Hypothesis: Mild hypothermia using non-invasive temperature management system in a stroke unit is safe and feasible in spontaneously breathing, alteplase-thrombolyzed patients with acute ischemic stroke.
- Trial name
- NCT00987922
- Testing
- Hypothermia
- Volunteers
- 36 people
- Sponsor
- University of Helsinki
End Stage Renal Failure on Dialysis
Impact of Cold Dialysis in Combination With Intradialytic Exercise in Aspects Related to Quality of Life and Health
Despite the tremendous advances in dialysis technology, hemodialysis (HD) is a significant challenge for dialysis patients and quality of their lives[2].
- Trial name
- REACD (NCT03905551)
- Testing
- Cold Dialysis, Typical Dialysis, Exercise
- Where
- 3 sites in Greece
- Volunteers
- 72 people
- Sponsor
- University of Thessaly
Spastic Hemiplegia
Effect of Dry Needling on Spasticity in Stroke Survivors.
Stroke is a disruption of blood flow to brain either due to clot formation or rupturing of arteries.It is a leading cause of disability worldwide with many consequences and spasticity is one of them.Spasticity is a resistance to…
- Trial name
- NCT05449951
- Testing
- Dry needling, sustained stretching
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Shifa Tameer-e-Millat University
Healthy
A Study to Learn How the Study Medicine PF-07899895 Are Tolerated and Act in the Body of Healthy Adults
The purposes of the study are as follows: To understand how safe and tolerable are different amounts of study medicine (PF-07899895). To measure the amount of PF-07899895 in blood after the medicine is taken by mouth.
- Trial name
- NCT06137729
- Testing
- PF-07899895
- Where
- Belgium
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Pfizer
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