Clinical trials: Modification
Astigmatism
Effect of Eye Movement on Toric Lens Orientation and Visual Acuity
The relative performance of a new toric soft contact lens against toric contact lenses currently available in market, specifically for visual acuity and lens orientation.
- Trial name
- NCT00584831
- Testing
- senofilcon A, balafilcon A, omafilcon A
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Stroke
Understanding Changes in Heart Function After Exercise in People With Stroke
Little is known about how exercise can affect heart function in stroke survivors. This study will look at changes in cardiovascular fitness and function after 6 months of exercise.
- Trial name
- NCT01189045
- Testing
- Aerobic Exercise Program, Non-aerobic Exercise Program
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Diarrhea-predominant Irritable Boewl Syndrome
Efficacy and Safety of Modified Gegen Qinlian Decoction for Diarrhea-predominant Irritable Boewl Syndrome
Diarrhea-predominant irritable boewl syndrome(IBS-D) seriously affect the quality of life in patients. Clinically, it is effective to apply therapeutic method of clearing heat and promoting diuresis to the common syndrome of…
- Trial name
- NCT04312477
- Testing
- Modified Gegen Qinlian Decoction
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
Public Health Nursing
The Effect of the Mobile Software Let's Move Program on Changing Sedentary Behaviors of University Students
Sedentary life means a physically inactive, sedentary life and is the fourth largest risk factor for death worldwide. It is reported that 70% to 85% of young people between the ages of age, representing 15.6% of the population of…
- Trial name
- NCT05883930
- Testing
- 'Let's Move' program, no intervention
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Marmara University
Pregnancy, Dietetics
Efficacy of Family-based Dietary Counseling During Pregnancy on Gestational Weight Gain in Pregnant Women in a Randomized Controlled Trial
The study aims to evaluate the efficacy of a family-based dietary monitoring during pregnancy on gestational weight gain in pregnant women.
- Trial name
- FAM-DIET (NCT06646965)
- Testing
- individual dietetic counseling, family-based dietetic conseling
- Where
- 3 sites in France
- Volunteers
- 1,374 people
- Sponsor
- University Hospital, Toulouse
Decreasing Wound Infection
The Impact of Changing Gloves During Cesarean Section on Post-operative Wound Complication
The investigators aim to compare the effect of changing their outer surgical gloves with a new pair of sterile gloves just prior to abdominal closure versus no intervention in the incidence of postoperative wound infections in…
- Trial name
- NCT04006067
- Testing
- changing surgical gloves
- Where
- Saudi Arabia
- Volunteers
- 600 people
- Sponsor
- khalid abd aziz mohamed
Dietary Modification
Breads Made With Triticum Heritage Varieties: Effect on Post-prandial Glycemia and Insulinemia
Wheat is one of the most important crop for humans and it represents a source of multiple nutrients, dietary fiber and bioactive compounds, especially if consumed as wholegrain.
- Trial name
- NCT03710200
- Testing
- Bologna 00+S. cerevisiae yeast, Bologna 1+S. cerevisiae yeast, Bio2+S. cerevisiae yeast
- Where
- Italy
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Parma
Post Operative Pain
Comparison of M-TAPA and TAP Blocks on Postoperative Analgesia in Laparoscopic Inguinal Hernia Surgeries
The goal of this study is to compare the analgesic efficacy of M-TAPA block and TAP block in patients undergoing laparoscopic inguinal hernia surgeries.
- Trial name
- NCT06483607
- Testing
- M-TAPA block with bupivacaine 25%, TAP block with bupivacaine 25%
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Cumhuriyet University
Overweight, Obese
Physical Activity and Health Outcomes
Obesity is common in adults with complex medical problems with ensuing complications afterwards. Obese patients suffer higher mortality and impaired functional status often as a result of their obesity.
- Trial name
- PAHO (NCT01833507)
- Testing
- Self-Exercise, Usual Care
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Multiple Sclerosis, Neurodegeneration
Central and Peripheral Nervous System Changes as Markers of Disease Progression in Multiple Sclerosis
OBJECTIVE To investigate neurodegeneration and demyelination in the central and peripheral nervous system in multiple sclerosis linked to disease progression and mechanisms that can explain different responses to Fampridine…
- Conditions
- Multiple Sclerosis, Neurodegeneration, Central Nervous System Lesion, Peripheral Nervous System Problem
- Trial name
- NCT03401307
- Where
- Denmark
- Volunteers
- 49 people
- Sponsor
- University of Southern Denmark
Phlebitis
Peripheral Venous Catheter Trial: 3 Day Versus No Routine Change
The purpose of this study is to investigate the effects of extending the dwell time of peripheral intravenous cannulas on clinical outcomes and cost.
- Trial name
- NCT00103636
- Testing
- Extending peripheral intravenous (IV) cannula dwell times
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Royal Brisbane and Women's Hospital
Adolescent Behavior, Lifestyle Modification
A Family-centred Approach Enhancing Cardiovascular Health in Ugandan Adolescents and Their Families
The FaCe-D Study, with funding from the Canadian Institute for Health Research (CIHR) through Global Alliance for Chronic Diseases (GACD) aims to adapt and implement an evidence-based family centred approach (FCA) to prevent…
- Conditions
- Adolescent Behavior, Lifestyle Modification, Cardiovascular Disease Other
- Trial name
- FaCe-D (NCT07265453)
- Testing
- The immediate (treatment) arm, will receive the FaCe-D intervention comprising of 'HOME VISITS, DIET, PHYSICAL ACTIVITY AND HEALTH MESSAGING, Control Arm - standard of care
- Where
- 2 sites in Uganda
- Volunteers
- 1,280 people, healthy volunteers welcome
- Sponsor
- MRC/UVRI and LSHTM Uganda Research Unit
Cachexia, HIV Infections
A Phase I/II Study to Evaluate Single Agent and Combination Therapy With Megestrol Acetate and Dronabinol for the Treatment of HIV-Wasting Syndrome
To obtain data on the safety of administering megestrol acetate and dronabinol as single agents or in combination to patients with human immunodeficiency virus (HIV)-wasting syndrome.
- Conditions
- Cachexia, HIV Infections, HIV Wasting Syndrome
- Trial name
- NCT00000737
- Testing
- Dronabinol, Megestrol acetate
- Where
- 9 sites in United States
- Volunteers
- 56 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Chewing Problem, Mastication Disorder
Masticatory Side Change and Masticatory Function.
The primary objective of this study is to establish the effect of the frequency of masticatory side switches on masticatory performance.
- Trial name
- NCT04714437
- Testing
- F, R, L
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Cancer, Cancer Cachexia
Effects of WB-EMS and Dietetic Treatment on Cancer Patients
This study evaluates the effects of a 12-week whole-body electromyostimulation (WB-EMS) training combined with individualized nutritional support on body composition, muscle strength and function and quality of life of patients…
- Conditions
- Cancer, Cancer Cachexia, Weight Loss, Muscle Loss
- Trial name
- NCT02293239
- Testing
- Whole-Body Electromyostimulation (WB-EMS)
- Where
- Germany
- Volunteers
- 278 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Comparative Bioavailability
Bioequivalence Study of Gliclazide 120 mg Modified Release Tablets
The main purpose of this study is to assess comparative bioavailability of two test formulations of Gliclazide 120 mg Modified Release tablets (120 mg gliclazide per modified release tablet) Manufactured By Indeus Life Sciences…
- Trial name
- NCT02980757
- Testing
- Gliclazide 120 mg MR Tablets Formula A, Gliclazide 120 mg MR Tablets, Gliclazide 120 mg MR Tablets Formula B
- Where
- Jordan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Disphar International B.V.
Peripheral Arterial Disease, Intermittent Claudication
The Effects of Metformin on Functional Capacity in Individuals With Peripheral Artery Disease-Related Intermittent Claudication
The purpose of this study is to determine the effects of metformin on functional capacity (pain-free and maximum walking times) in individuals with peripheral artery disease (PAD)-related intermittent claudication.
- Trial name
- NCT01799057
- Testing
- Metformin
- Where
- Australia
- Volunteers
- 2 people
- Sponsor
- Baker Heart and Diabetes Institute
Obesity, Bariatric Surgery Candidate
Does Text Message Support After Discharge Improve Outcomes Following Bariatric Surgery? A Randomised Trial.
The purpose of this study is to determine whether text message support after discharge from a bariatric service improves outcomes following bariatric surgery.
- Trial name
- NCT02341001
- Testing
- Daily text message of support
- Where
- New Zealand
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Acute Gastroenteritis, Dehydration
Continuous Enteral Rehydration by Nasogastric Tube With ORS in Children With Acute Gastroenteritis
When oral rehydration is impossible, enteral rehydration via the nasogastric route has been the recommended method of rehydration since 2008 by ESPGHAN ( European Society for Paediatric Gastroenterology Hepatology and Nutrition…
- Trial name
- GEA (NCT04555200)
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Brest
Body Composition Changes
Magnesium Supplementation on Body Composition
The goal of this interventional clinical trial is to learn if the supplementation of magnesium can affect body composition in physically active individuals between the ages of 18 and 30.
- Trial name
- NCT06703099
- Testing
- Magnesium Supplementation
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
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