Clinical trials: Modification
Renal Stones
Management of Medium Sized Renal Stones
Urinary stone disease is a common urological condition that affects millions of people worldwide, often leading to significant morbidity and healthcare costs.
- Trial name
- NCT06720311
- Testing
- Modified Tubeless Super-Mini Percutaneous Nephrolithotomy, Flexible Ureterorenoscopy, Shockwave Lithotripsy
- Volunteers
- 90 people
- Sponsor
- Assiut University
Breast Reconstruction, Breast Cancer
Comparison of PEAK PlasmaBlade™ to Conventional Diathermy in Abdominal Based Free Flap Breast Reconstruction
Electrosurgery allows for dissection with simultaneous haemostasis. One of its disadvantages is that the heat production can cause injury to the surrounding tissue which may result in wound healing problems and an increased rate…
- Trial name
- NCT04350411
- Testing
- Conventional diathermy, PEAK PlasmaBlade™
- Where
- United Kingdom
- Volunteers
- 108 people
- Sponsor
- Anglia Ruskin University
Bone Disease, Metabolic, Osteopenia
Electromagnetic Treatment For Bone Loss After Forearm Fracture
This study will determine the usefulness of pulsing electromagnetic field (PEMF) technology to reverse or reduce the bone loss (osteopenia) that occurs in the forearm after fracture or surgery.
- Conditions
- Bone Disease, Metabolic, Osteopenia, Osteoporosis, Post-Traumatic
- Trial name
- NCT00067834
- Testing
- Pulsing electromagnetic field (PEMF)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Substance Use Disorders
A Randomized Controlled Trial of Culturally Adapted Evidence-based Treatment With a Southwest Tribe
This study combined, adapted and tested motivational interviewing (MI) and the Community Reinforcement Approach (CRA) as a culturally congruent treatment approach for Native Americans.
- Trial name
- MICRA (NCT05938764)
- Testing
- MICRA, TAU
- Volunteers
- 87 people
- Sponsor
- University of New Mexico
Internet Gaming Disorder
Emotional Association Bias Modification Training in Individuals With IGD
This project aims to investigate (1) the efficacy of emotional association bias modification (EABM) training on internet gaming disorder (IGD); (2) the underlying neural mechanisms of such efficacy
- Trial name
- NCT04068064
- Testing
- EABM training
- Where
- China
- Volunteers
- 87 people
- Sponsor
- Beijing Normal University
Overweight and Obesity
Neurocognitive Benefits of a Weight Management Program
This study will assess whether weight loss induced through diet and physical activity can change neural responses to high- and low-calorie food images.
- Trial name
- NCT04202133
- Testing
- WW (formerly Weight Watchers), Waitlist
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Denture Stomatitis
Surface Roughness of Heat Cured Acrylic Resin Versus Acrylic Resin With Titanium Dioxide
Measurement of surface roughness of tow different material of denture base to find out which material is more hygienic by decreasing the amount of bacterial accumulation.
- Trial name
- NCT02950584
- Testing
- Titanium dioxide denture, Rapid heat denture
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Weakness, Muscle, Muscle Weakness
Short Term Immobilization of the Lower Limb
The purpose of this study is to determine the effects of one week of knee-joint immobilization on muscle size, strength, neuromuscular function, and brain function.
- Conditions
- Weakness, Muscle, Muscle Weakness, Muscle Loss, Muscle Atrophy
- Trial name
- STILL (NCT05072652)
- Testing
- Neuromuscular Electrical Stimulation, Action Observation + Mental Imagery
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Hemorrhoids, Open Hemorrhoidectomy
Hemorrhoids: Options of Traditional Hemorrhoidectomy
The goal of this prospective clinical trial is to compare the outcomes of several technical options of open hemorrhoidectomy in patients with symptomatic hemorrhoids.
- Trial name
- NCT06132152
- Testing
- Open hemorrhoidectomy with 'cold' scalpel, Open hemorrhoidectomy with electrosurgical scalpel
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- Center of Endourology "Endocenter"
PSA Changes After TURP
Serum Prostatic Specific Antigen Changes After Bipolar and Monopolar TURP
To use PSA levels after bipolar and monopolar transurethral resection of the benign prostatic hyperplasia as an indicator of the quality of resection .
- Trial name
- NCT05533047
- Testing
- TURP
- Volunteers
- 2 people
- Sponsor
- Assiut University
Narcolepsy
Metabolism Characteristics in the Children With Narcolepsy
A significant weight gain and obesity are observed for most patients with narcolepsy, mainly at the beginning of the disease and narcolepsy in young children.
- Trial name
- Narcolepsy (NCT02799849)
- Testing
- Sleep and metabolism assessment
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Hospices Civils de Lyon
Obesity
Supplemental Calcium in Overweight People
This study will examine the health effects of calcium supplements in overweight adults. Overweight adults often eat a diet low in calcium.
- Trial name
- NCT00030238
- Testing
- Calcium supplement
- Where
- United States
- Volunteers
- 540 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Class II Malocclusion
Modified Herbst Approach to Improve Chin Projection
This study will collect data to try to assess which one of the two management options works better. The first option involves the use of the bite corrector first and then braces, while the second option involves the temporary…
- Trial name
- NCT05597748
- Testing
- Modified Herbst Approach, Conventional Herbst Approach
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alberta
Cognitive Change, Stress, Psychological
Acute and Chronic Effects of Avena Sativa on Cognition and Stress
The flavanoid and terpene phytochemicals present in wild green oat interact with multiple mechanisms relevant to brain function; including those which would modulate cognition and stress.
- Conditions
- Cognitive Change, Stress, Psychological, Mood
- Trial name
- NCT03689348
- Testing
- Avena sativa
- Where
- United Kingdom
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Cardiac Arrest
Measurement of Core Temperatures During Therapeutic Hypothermia
The purpose of this study is to determine that the measurements of rectal and bladder temperature are correctly consistent with core temperature by using the pulmonary artery catheter during therapeutic hypothermia; rapid…
- Trial name
- TH (NCT01292148)
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul National University Hospital
Mitrofanoff Continent Cystostomy, Cystostomy; Complications
Modified Step by Step Mitrofanoff Continent Cystostomy : Functional Results of a Teachable Procedure
The creation of an abdominal continental cystostomy orifice is an irreplaceable surgical technique that allows for the simple self-sounding of the bladder in patients with severe disabilities or malformations, and to obtain…
- Trial name
- MCCR (NCT04539743)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Grenoble
Stroke, Electroencephalogram
CEEG Changes After Tdcs and Dual-task Training
Stroke has been considered one of the main causes of long-term disability in the adult population. Technological advances in the neurological area have been observed in the last decades, which accentuates the interest in…
- Trial name
- NCT05492435
- Testing
- transcranial direct current stimulation
- Where
- Brazil
- Volunteers
- 35 people
- Sponsor
- Federal University of Paraíba
Airway Inflammation, Asthma
An Exploratory Study to Characterise Changes in Airway Inflammation, Symptoms, Lung Function and Reliever Use in Adult Asthma Patients
This is a randomised, active-comparator, open-label, parallel-group, multicentre phase IV exploratory study to characterise changes in airway inflammation, symptoms, lung function, and reliever use in asthma patients using SABA…
- Trial name
- NCT03924635
- Testing
- SYMBICORT and salbutamol
- Where
- 6 sites in United Kingdom
- Volunteers
- 42 people
- Sponsor
- AstraZeneca
Primary Mediastinal Lymphoma
Nivolumab 40 mg in Combination With Chemo-Immunotherapy for Newly Diagnosed Primary Mediastinal B-Cell Lymphoma
This compares the effects of nivolumab at a fixed dose of 40 mg with chemo-immunotherapy versus chemo-immunotherapy alone in treating patients with newly diagnosed primary mediastinal B-cell lymphoma (PMBCL).
- Trial name
- NCT06188676
- Testing
- Cyclophosphamide, Doxorubicin Hydrochloride, Etoposide Phosphate
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- National Research Center for Hematology, Russia
Anxiety
Investigating Predictors of Outcomes From LENS
Anxiety is a very common mental health problem. For people living with anxiety, it can have a huge impact on their lives. There are treatments that can help, such as Cognitive Behavioural Therapy (CBT).
- Trial name
- NCT07339917
- Testing
- Learning Effective New Strategies (LENS)
- Volunteers
- 4,400 people
- Sponsor
- King's College London
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