Clinical trials: Mohs Micrographic Surgery
Basal Cell Carcinoma, Squamous Cell Carcinoma
Absorbable Suture Versus Tissue Glue to Repair Defects Following Mohs Surgery
The purpose of the study is to look at which nonpermanent superficial closure method, cyanoacrylate tissue glue or fast absorbing gut suture, leads to a better cosmetic and functional outcome in repairs of facial wounds after…
- Trial name
- NCT01298167
- Testing
- Cyanoacrylate tissue glue versus Fast absorbing gut
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Yale University
Skin Cancer
Spectrally Guided Mohs Surgery
Freshly excised or freshly frozen tissue for Raman analysis will be obtained from a dermatology practice affiliated with UMCB. In the course of the routine removal of benign or malignant tumors in the office, skin cancer surgeons…
- Trial name
- NCT03145506
- Testing
- Multimodal Spectroscopy
- Volunteers
- 24 people
- Sponsor
- Seton Healthcare Family
Impaired Wound Healing
Secondary Intention Wound Healing Versus Micrografting in Patients Undergoing Mohs Surgery
This study evaluates a novel micrografting technique to see how it will influence the healing rate and cosmetic result of second intention wounds.
- Trial name
- MomelanMohs (NCT01442844)
- Testing
- Micrografting
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Massachusetts General Hospital
Surgical Site Infection, Skin Cancer
Cyanoacrylate Skin Adhesive After Mohs Surgery or Wide Local Excision
This study will compare surgical site infection after linear repair with or without cyanoacrylate skin adhesive following Mohs micrographic surgery or wide local excision.
- Conditions
- Surgical Site Infection, Skin Cancer, Wound Healing
- Trial name
- NCT07844681
- Testing
- Cyanoacrylate Skin Adhesive, Fast Gut Running Epidermal Suture Closure, Vicryl Rapide Running Epidermal Suture Closure
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Minnesota
Nonmelanoma Skin Cancer
Comparison of eBX and Mohs Surgery for Treatment of Early-stage Non-melanoma Skin Cancer a Matched Pair Cohort Study.
This is a retrospective-prospective study design. Patients who completed treatment approximately 3 years (range of 2-4 years) at time of IRB approval of this study will be identified and any existing data in the patient's record…
- Trial name
- NCT03024866
- Testing
- Electronic Brachytherapy
- Where
- 4 sites in United States
- Volunteers
- 369 people
- Sponsor
- Xoft, Inc.
Skin Cancer, Skin Carcinoma
Effects of Lavender Aromatherapy on Patient Anxiety During Mohs Micrographic Surgery
This study aims to improve patient comfort by exploring the potential of lavender aromatherapy in reducing anxiety and unpleasant odor perception during Mohs Micrographic Surgery (MMS).
- Trial name
- NCT06167096
- Testing
- Lavender essential oil, Water
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Case Comprehensive Cancer Center
Wound Edges
Intraoperative CO₂ (Carbon Dioxide)
To evaluate whether intraoperative fractionated CO₂ laser treatment of surgical wound edges improves postoperative scar appearance compared with untreated wound edges following Mohs micrographic surgery (MMS).
- Trial name
- NCT07592468
- Testing
- CO2 Fractionated Laser, Non CO2 Laser Treatment
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Baylor Research Institute
Actinic Cheilitis, Squamous Cell Carcinoma In-situ (SCC-is)
Photodynamic Therapy to Treat Actinic Damage in Patients With Squamous Cell Carcinoma (SCC) of the Lip
Our study is designed to evaluate the efficacy of photodynamic therapy (PDT) for treatment of actinic cheilitis (AC) and as an adjunct to Mohs surgery for squamous cell carcinoma (SCC) on the lips.
- Conditions
- Actinic Cheilitis, Squamous Cell Carcinoma In-situ (SCC-is), Squamous Cell Carcinoma (SCC), Photodynamic Therapy (PDT)
- Trial name
- NCT00868088
- Testing
- PDT prior to Mohs surgery
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Tufts Medical Center
Basal Cell Carcinoma, Squamous Cell Carcinoma
Effect of the Subconscious on Mohs Micrographic Surgery
The goal of this study is to determine if relaxation therapy improves patient satisfaction with Mohs micrographic surgery.
- Trial name
- NCT00374062
- Testing
- relaxation therapy 1, relaxation therapy 2, relaxation therapy 3
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Malignant Skin Neoplasm
Website Application Based Education and Text Messaging in Improving Skin Wound Care in Patients Undergoing Mohs Surgery
This randomized clinical trial studies how well website application (web app) based education and text messaging works in improving skin wound care in patients undergoing Mohs surgery (a surgical procedure used to treat skin…
- Trial name
- NCT02373722
- Testing
- Mohs Surgery, Internet-Based Intervention, Telephone-Based Intervention
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Wake Forest University Health Sciences
Wound Heal
Dermabrasion in Mohs: Split-Scar Trial
The purpose of this study is to determine the potential influence of intraoperative dermabrasion on scars following Mohs Micrographic Surgery (MMS).
- Trial name
- NCT07213921
- Testing
- Dermabrasion
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Wound Heal
Safety of Microporous Annealed Particle (MAP) Wound Matrix in Patients With Clean Surgical Wounds.
A randomized, open-label, investigational safety evaluation of the Microporous Annealed Particle (MAP) Wound Matrix (TT101) device as a volumetric biomaterial scaffold applied to clean wounds after skin cancer surgery with Mohs…
- Trial name
- MOSAIC (NCT06600152)
- Testing
- MAP Wound Matrix, DuoDerm
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Tempo Therapeutics
Mohs Micrographic Surgery
3D Printed Models in Mohs Micrographic Surgery
Patients undergoing Mohs micrographic surgery (MMS) frequently experience anxiety. It has been suggested that enhanced patient education prior to the procedure may decrease patient anxiety.
- Trial name
- NCT03461965
- Testing
- 3D printed model, Verbal Counselling
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Case Comprehensive Cancer Center
Skin Neoplasms
Use of Tranexamic Acid in Reduction of Post-Op Complications in Mohs Micrographic Surgery
The purpose of this study is to evaluate the use of locally injected tranexamic acid (TXA) under the skin during Mohs micrographic surgery for removal of skin cancers in patients on anticoagulation.
- Trial name
- NCT04630886
- Testing
- Tranexamic acid injection, Lidocaine Epinephrine
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Riley McLean
Skin Substitutes, Secondary Intention Healing
Skin Subs vs Secondary Intention
The purpose of this study is to compare two ways of caring for wounds after Mohs micrographic surgery (MMS) for skin cancer using skin substitutes and secondary intention healing, to determine which option leads to better healing…
- Conditions
- Skin Substitutes, Secondary Intention Healing, Skin Cancer Healing
- Trial name
- NCT07587749
- Testing
- Skin Substitute, Secondary Intention Healing
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Baylor Research Institute
Mohs Micrographic Surgery, Anesthesia, Local
Local Anesthetic Clinical Trial
To compare several local anesthetics when used during dermatological surgery.
- Trial name
- NCT07601750
- Testing
- Lidocaine, Bupivacaine Hydrochloride, Mepivacaine Hydrochloride
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Baylor Research Institute
Corneal Toxicity, Ototoxicity
A Comparison of Infection Rates Between Two Surgical Sites
Does the use of chlorhexidine scrub prior to cutaneous surgery on the face increase the chances of toxicity to the eyes or ears? In addition, does the us eof chlorhexidine scrub on the face prior to cutaneous surgery decrease the…
- Conditions
- Corneal Toxicity, Ototoxicity, Surgical Site Infection
- Trial name
- NCT01263262
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic