Clinical trials: Molar, Third
Periodontal Pocket, Impacted Third Molar Tooth
Evaluation of Two Different Grafting Techniques After Mandibular Impacted Third Molar Surgery
This study evaluates the effectiveness of using Mineralized Plasmatic Matrix and β-tricalcium phosphate that placed to extraction socket as a graft material in terms of periodontal damage occurred in the distal aspect of the…
- Conditions
- Periodontal Pocket, Impacted Third Molar Tooth, Impacted Teeth With Abnormal Position
- Trial name
- NCT04366635
- Testing
- Impacted third molar surgery, Application of mineralised plasmatic matrix, Application of β-tricalcium phosphate
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Healthy, Tooth Extraction
Capsaicin to Control Pain Following Third Molar Extraction
Capsaicin to Control Pain Following Third Molar Extraction Summary: This study will test the effectiveness of the drug capsaicin in controlling pain after third molar (wisdom tooth) extraction.
- Trial name
- NCT00088686
- Testing
- Capsaicin (Intramucosal Injection)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Periodontal Defect
Effect of Collagen Membranes on Distal Periodontal Healing of Second Molars After Impacted Mandibular Third Molar Surgery.
Impacted mandibular third molars can cause various complications to the adjacent second molars, such as dental caries, periodontitis, or root resorption. These complications often progress silently and asymptomatically.
- Trial name
- NCT07114523
- Testing
- collagen membrane, third molar surgery
- Where
- Vietnam
- Volunteers
- 20 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Dry Socket, Postoperative Infections
The Effect of Chlorhexidine + Hyaluronic Acid on Postoperative Wound Healing After Lower Third Molar Removal
Our aim is to evaluate chlorhexidine-hyaluronic acid containing gel on postoperative wound healing regarding impacted lower third molar surgery.
- Trial name
- NCT07044219
- Testing
- Third molar surgery
- Where
- Hungary
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Trismus, Swelling
Comparison of Two Different Suture Knot Techniques on Post-Operative Trismus and Swelling After Impacted Third Molar Surgery
To compare the two different suture knot techniques, locked and unlocked, in terms of mean on postoperative trismus and swelling after impacted mandibular third molar surgery.
- Trial name
- Impacted molar (NCT07327762)
- Testing
- locking and non locking suture techniques, non locking suture technique
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Watim Medical & Dental College
Postsurgical Pain, Third Molar Extraction
Efficacy and Safety of APSCTC for the Treatment of Postsurgical Pain Due to Third Molar Extraction
The purpose of this study is to evaluate the efficacy of APSCTC compared to two active drugs in acute pain relief.
- Trial name
- CARLOTA (NCT04647435)
- Testing
- APSCTC, Toragesic®, Tramal®
- Where
- Brazil
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- Apsen Farmaceutica S.A.
Impacted Tooth, Postoperative Complications in Maxillofacial Surgery
Effectiveness of Postoperative Topical and Oral Antibiotics on Impacted Mandibular 3rd Molar Surgery.
This randomized controlled trial evaluates the effectiveness of postoperative topical antibiotics compared with oral antibiotics in patients undergoing surgical extraction of impacted mandibular third molars.
- Conditions
- Impacted Tooth, Postoperative Complications in Maxillofacial Surgery, Surgical Wound Infection, Facial Pain
- Trial name
- POTA-M3S (NCT07573033)
- Testing
- Topical Antibiotic, Oral antibiotic therapy
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Liaquat College of Medicine and Dentistry
Pain
Genetic Basis For Variation In NSAID Analgesia In A Clinical Model Of Acute Pain
This study will evaluate how genetic makeup contributes to the variation in people regarding their sensitivity to and experience of pain.
- Trial name
- NCT00115752
- Testing
- Valdecoxib, COX Inhibitor
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Healthy Patients
Evaluation of Heart Rate Variability in Third Lower Molars Surgeries
The purpose of this study is to use heart rate variability as a monitor of cardiovascular safety during third molar surgeries, using the Polar heart rate-meter.
- Trial name
- NCT01910337
- Testing
- Use the Polar Cardiac rate meter
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Renata Martins da Silva Prado
Periodontal Diseases
Third Molars Extraction and Periodontal Disease
The aim of the study is to evaluate the changes in periodontal conditions on the distal aspect of the second maxillary molar after the extraction of the maxillary wisdom tooth.
- Trial name
- NCT06520137
- Testing
- Tooth extraction
- Where
- Italy
- Volunteers
- 126 people
- Sponsor
- Azienda Ospedaliera Universitaria Senese
Dental Pain
Study of Diclofenac Capsules to Treat Dental Pain
The purpose of this study is to determine whether Diclofenac Test Formulation Capsules are safe and effective for the treatment of dental pain.
- Trial name
- NCT00985439
- Testing
- Diclofenac Test (lower dose), Diclofenac Test (upper dose), Celecoxib 400 mg
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Iroko Pharmaceuticals, LLC
Postoperative Edema and Pain
Third Molar Extraction and Pulsed Electromagnetic FieldTherapy
This study is a prospective, randomized, double-blinded, controlled, clinical trial that evaluates the efficacy of using PEMF in the postoperative period in decreasing swelling and pain after extraction of impacted third molars.
- Trial name
- PEMF (NCT02376946)
- Testing
- ActiPatch(TM)
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Tufts University
Impacted Third Molar Tooth, Pain, Acute
Variability in Analgesic Response to Ibuprofen
Nonsteroidal anti-inflammatory drugs (NSAIDs), like ibuprofen, are recommended as first-line treatment for post-surgical dental pain.
- Trial name
- NCT06539741
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Pain
Study to Investigate the Analgesic Efficacy of a Single Dose of AZD1386
The primary aim of this study is to investigate if AZD1386 can relieve the pain induced by the surgical removal of one lower wisdom-tooth.
- Trial name
- NCT00672646
- Testing
- AZD1386, Naproxen
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Poly(Lactide-co-glycolide) Sutures, Suture Resorption
Comparative Analysis of fast-and Slow-absorbable Poly(Lactose-co-glycolide) Sutures in Oral Surgery: a Randomized Controlled Trial.
This study aims to compare slow-resorbing and fast-resorbing sutures used after the surgical extraction of lower third molars. Sutures are routinely placed after wisdom tooth removal to promote hemostasis.
- Conditions
- Poly(Lactide-co-glycolide) Sutures, Suture Resorption, Third Molar Surgery
- Trial name
- NCT07498361
- Testing
- Fast absorbable sutures application, Standard absorbable sutures application
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Padova, School of Dental Medicine
Morphologic Change, Number of Roots
Assessment of the Relationship Between Mandibular Third Molars' Roots & the Covering Lingual Cortex Among Egyptian Population Using CBCT
A cross-sectional study to assess the Topographic Relationship between Mandibular Third Molars' Roots and the Covering Lingual Cortex in a Sample of Egyptian Population using CBCT through retrospective data analysis
- Trial name
- NCT04567654
- Volunteers
- 304 people
- Sponsor
- Cairo University
Anxiety State, Pain
The Effect of Music and White Noise on Patients' Anxiety and Pain During Surgery for Impacted Mandibular Third Molar
The goal of this clinical trial is to evaluate the effect of music and whitenoise on the anxiety and pain level of patients who had impacted third molars surgery.
- Trial name
- NCT06814366
- Testing
- music and white noise intervention, music intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Cold Therapy
Is Cryotherapy Beneficial After Surgical Removal of Impacted Lower Third Molars?
The present study aimed to investigate the effects of cryotherapy on postoperative parameters (pain intensity, edema, trismus, and the quality of life) after lower third molar extraction.
- Trial name
- NCT07370870
- Testing
- Cold Therapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Henrique Tedesco
Post-operative Pain, Acute, Pain Threshold
Cold Press Test and Post Operative Pain Relationship
The goal of this clinical trial is to investigate whether it is possible to get a preliminary idea about the postoperative pain in the patient with the results of a practical cold press test applied to American Society of…
- Trial name
- NCT05904873
- Testing
- Mandibular Third Molar Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sinem Büşra Kıraç Can
Mandibular Nerve Injury
Study on the Risk of Inferior Alveolar Nerve Damage During Lower Third Molar Surgery
Objective The present study aimed to evaluate which factors were statistically associated with a greater probability of inferior alveolar nerve (IAN) damage during lower third molar surgery.
- Trial name
- NCT04807946
- Testing
- lower third molar extraction
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza