Clinical trials: Monitoring, Intraoperative
Surgery, Temperature Change, Body
Intraoperative Body Core Temperature Monitoring: Oesophageal Probe vs Heated Controlled Servo Sensor
Monitoring of intraoperative core temperature is essential for patient safety, reducing the risk of perioperative hypothermia. A recently developed measuring system, SpotOn® (3M, St.
- Trial name
- ESOSPOT (NCT03820232)
- Testing
- temperature monitoring
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Careggi Hospital
Involuntary Movements, Brain Surgery
Predictive Factors of Unpredicted Movement in Motor Evoked Potential
The purpose of this study was to identify the predictive factors of unpredicted movement in motor evoked potential (MEP) during intraoperative neurophysiologic monitoring in adult patients undergoing brain surgery.
- Trial name
- NCT03489785
- Where
- South Korea
- Volunteers
- 850 people
- Sponsor
- Seoul National University Hospital
Anesthesia, Emergence Delirium
The Effect of Anesthesia Depth Monitoring on Emergence Delirium in Pediatrics
Some changes in the patient's cognitive state are observed during the recovery period from general anesthesia. This period of behavioral dysregulation has been called emergence agitation (EA) and emergence delirium (ED).
- Conditions
- Anesthesia, Emergence Delirium, Anesthesia Awareness, Behavior Child Problems
- Trial name
- NCT06323616
- Testing
- MAC adjustment to PSI between 25 and 50
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Istanbul University
Cardiopulmonary Bypass Surgery, Left Ventricular Dysfunction
Assement of Left Ventricular Function Before Decannulation in Cardiac Surgery :Visual Estimation vs TEE
This study aims to evaluate the diagnostic performance of the cardiovascular surgeon's visual estimation of LV function before decannulation following cardiopulmonary bypass, using TEE results as the reference standard.
- Trial name
- LVFuncTee (NCT07286227)
- Testing
- Intraoperative Left Ventricular Function Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ataturk University
Hypercarbia
The Effect of Ketamine in the Prevention of Hypoventilation in Patients Undergoing Deep Sedation Using Propofol and Fentanyl
Procedures performed under sedation have the same severity in regards to morbidity and mortality as procedures performed under general anesthesia1.
- Trial name
- NCT01825083
- Testing
- Ketamine
- Where
- United States
- Sponsor
- Northwestern University
Pain
Evaluation of NoL Index and ANI After Nociceptive Stimulation at Different Infusion Rates of Remifentanil Infusion
Contrary to "immobility" and, to a lesser extent, to the "hypnosis/unconsciousness" component of general anaesthesia, the monitoring of "analgesia" remains largely elusive, evaluated mainly through poorly sensitive and…
- Trial name
- NCT02602379
- Testing
- Tetanic stimulation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Hemodynamic Monitoring
The EU Hyprotect Registry
European, multicenter, prospective, observational registry in patients undergoing elective major non-cardiac surgery
- Trial name
- NCT04972266
- Testing
- AcumenTM Hypotension Prediction Index software
- Where
- 12 sites in France, Germany and 3 more
- Volunteers
- 702 people
- Sponsor
- Edwards Lifesciences
Pain, Chronic, Lumbar Radiculopathy
Study on the Use of Intraoperative Neurophysiological Monitoring in Spinal Cord Stimulator Trials
This is an observational pilot study. The spinal cord stimulator (SCS) procedure and neuromonitoring device is not under investigation. Neuromonitoring is typically performed on this patient population receiving SCS trials here.
- Conditions
- Pain, Chronic, Lumbar Radiculopathy, SCS
- Trial name
- SCS-Monitor (NCT05540756)
- Where
- United States
- Sponsor
- University of Chicago
Fluid Overload
Body Composition Monitoring(BCM) for Determination of the Fluid Status in Patients Undergoing General Anesthesia
The purpose of this study is to evaluate a recently developed device, which measures body composition (i.e. the water content of the body) in the perioperative setting.
- Trial name
- BCM (NCT01945541)
- Testing
- Body Composition Monitoring
- Where
- Austria
- Volunteers
- 73 people
- Sponsor
- Medical University of Vienna
Preoperative Anxiety, Intraoperative Hemodynamics and Drug Consumption
Evaluation of the Effects of Preoperative Anxiety in Patients Undergoing Total Intravenous Anesthesia (TIVA)
Most patients have varying degrees of anxiety and fear before surgery. We believe that preopertive anxiety levels have an effect on intraoperative hemodynamics and recovery and affect intraoperative drug consumption.
- Trial name
- NCT04690764
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Anesthesia, Pain
Pupillometry Guided Remifentanil Administration In Pediatric Anesthesia
The aim of this prospective randomized study is to evaluate the impact of peroperative pupillometry monitoring on per and post-operative opioid consumption in pediatric anesthesia.
- Conditions
- Anesthesia, Pain, Child
- Trial name
- NCT02683837
- Testing
- Remifentanil, Pupillometry, Sevoflurane
- Where
- Switzerland
- Sponsor
- University Hospital, Geneva
Fluid Challenge, Hemodynamic Monitoring
Tidal Volume Challenge and Lung Recruitment Maneuver (TIDALREC): the Reliability of Pulse Pression Variation or Stroke Volume Variation on Fluid Responsiveness.
In order to predict fluid responsiveness in the operating room and therefore benefit of performing fluid administration to improve patient's hemodynamic status, it will test two ventilation strategies : the Tidal Volume Challenge…
- Trial name
- TIDALEC (NCT04535115)
- Testing
- Starting LRM (Lung Recruitment Maneuver), Starting VtC (Tidal Volume Challenge)
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Lille
Flap Ischemia, Hypoxia
Spectroscopic Assessment of Tissue Oxygenation Changes in Plastic Surgical Flap Reconstructions
This study is a single-center, observational study designed to collect tissue spectrometric data.
- Trial name
- NCT07786610
- Volunteers
- 30 people
- Sponsor
- Spectrocor
Intraoperative Hemodynamics
Physiological Reference Values of Total Arterial Impedance Derived From PRAM Monitoring
Total arterial impedance (Ztot) is an advanced hemodynamic parameter that reflects the global arterial load opposing ventricular ejection by integrating both steady and pulsatile components of the arterial system.
- Trial name
- PRAM-ZTOT (NCT07340333)
- Where
- Turkey (Türkiye)
- Volunteers
- 437 people
- Sponsor
- Ataturk University
Thyroid Surgery Intraoperative Nerve Monitoring (IONM) Recurrent Laryngeal Nerve Function Dexmedetomidine vs Midazolam (Anesthetic Agents)
EFFECT OF DEXMEDETOMİDİNE ON RECURRENT LARYNGEAL NERVE MONİTORİNG: A COMPARATİVE STUDY WİTH MİDAZOLAM
This prospective observational study evaluated the effect of dexmedetomidine compared with midazolam on intraoperative monitoring of the recurrent laryngeal nerve during thyroid surgery.
- Trial name
- DEX-RLN (NCT07195214)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Amasya University
Major Abdominal Surgeries, Mechanical Ventilation
Intraoperative Multimodal Monitoring as a Means in Reducing the Duration of Mechanical Ventilation in High-Risk Patients Undergoing Major Abdominal Procedures - A Pilot Study
This study will include patients aged 50 and older scheduled for elective abdominal oncologic surgery, classified as ASA II and III due to increased anaesthetic and surgical risk. Gender will not be a stratification factor.
- Trial name
- IMMEDIUM (NCT07339449)
- Testing
- Multimodal monitoring
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- University Hospital Dubrava
All Conditions Requiring Non-cardiac Surgery
Impact of Training on the Use of Software and Digital Monitoring Tools During General Anesthesia for Intermediate/Major-risk Surgery on Morbidity and Mortality at 28 Days
Tools such as surgical plethysmographic index, state entropy, train-of-four monitors exist to optimize the conduct of general anesthesia in intermediate and major risk surgery as defined by the 2022 European Society of Cardiology…
- Trial name
- AoA QUALITY (NCT06111248)
- Testing
- Training
- Where
- France
- Volunteers
- 1,028 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Pain Monitoring, Pain Assessment
Intraoperative Analgesia Based on ANI
Osteoarthritis of the knee joint is common and total knee arthroplasty (TKA) is performed in patients with advanced joint degeneration, no response to conservative treatments, severe pain and joint instability.
- Conditions
- Pain Monitoring, Pain Assessment, Opioid Consumption
- Trial name
- NCT06236035
- Testing
- Analgesia nociception index
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Neuromuscular Blockade, Neuromuscular Monitoring
Development and Validation of an Android-based Application for Anaesthesia Neuromuscular Monitoring
The present study aims to assess the accuracy of a newly developed Android Smartphone Application in measuring the degree of Neuromuscular block in the perioperative period.
- Trial name
- NCT03605225
- Testing
- mobile cellphone application test
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- Universitair Ziekenhuis Brussel
Intraoperative Ureter Injury
Open-label Study to Evaluate Nerindocianine as a Surgical Aid in Ureter Delineation During Minimally Invasive Surgery
Phase 2, multicenter, efficacy and safety study evaluating the use of nerindocianine for the delineation of abdominopelvic ureter anatomy via near infrared fluorescence imaging during minimally invasive lower abdominal surgery…
- Trial name
- NCT04636567
- Testing
- Nerindocianine for injection
- Where
- 2 sites in United States
- Sponsor
- Li-Cor, Inc.