Clinical trials: Monitoring, Physiologic
Vital Signs Monitoring, Newborn Monitoring
Miniaturized Vital Sign Monitoring for Newborns in the Delivery Room
This prospective observational study aims to evaluate the accuracy, safety, and feasibility of the Wireless MicroPremVitals Button Sensor System for continuous monitoring of electrocardiography (ECG), heart rate, respiratory…
- Conditions
- Vital Signs Monitoring, Newborn Monitoring, Physiologic Monitoring
- Trial name
- NCT07739810
- Testing
- Wireless MicroPremVitals Button Sensor
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Humans, Urinary Incontinence
Intraoperative Nerve Monitoring During Robotic-assisted Radical Prostatectomy
The purpose of this study is to evaluate whether the use of intraoperative nerve monitoring during robotic-assisted radical prostatectomy (RARP) can predict and improve post-surgery urinary continence and erectile function.
- Conditions
- Humans, Urinary Incontinence, Male Urogenital Diseases, Prostatectomy
- Trial name
- NCT03721029
- Testing
- Intraoperative nerve monitoring,, standard of care robotic-assisted radical prostatectomy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
ARDS
Incremental and Decremental PEEP Titration by Diverse Strategies in Subjects With ARDS: A Prospective Physiological Study
The investigators conducted a prospective physiological observation study on ARDS population, described their physiological and EIT indexes with various PEEP titration methods, and also compared and analyzed those indexes to…
- Trial name
- ARDS，PEEP (NCT06808438)
- Testing
- Esophageal pressure catheter
- Where
- China
- Volunteers
- 31 people
- Sponsor
- West China Hospital
Complication,Postoperative
Continuous Wireless Monitoring of Vital Signs and Automated Alerts of Postsurgical Patient Deterioration.
The primary aim of the current study is to assess the effect of continuous wireless vital sign monitoring with generation of real-time alerts, compared to blinded monitoring without alerts on the cumulative duration of any…
- Trial name
- WARD-RCT-SX (NCT04640415)
- Testing
- Active Alarms
- Where
- 2 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Healthy Subjects
Monitoring Changes in Physiological Parameters by Utilization of the Combined Physiological Activity Index (CPAI)
A clinical trial to validate the MCPM (Multi-parameter Combined Physiological Signal-based Monitoring), in estimating physiological activity level, at rest, previous and following stimuli.
- Trial name
- NCT03508063
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Medasense Biometrics Ltd
General Anesthetic Drug Adverse Reaction
Predicting Outcomes Using Infra-red SEnsors, a Feasibility Study.
The aim of this study is to investigate if it is feasible to use a protocol in which avoiding oxygen desaturation in the brain during general anaesthesia can reduce the risk of negative postoperative behavior changes in children.
- Trial name
- PORPOISE-F (NCT06515080)
- Testing
- Near Red Infrascopy
- Where
- 5 sites in Australia, Belgium and 3 more
- Volunteers
- 500 people
- Sponsor
- Uppsala University
Gastroesophageal Reflux
Physiological Predictors of Clinical Outcomes After Anti-reflux Surgery
Gastro-oesophageal reflux disease (GORD) is a common condition, where acid from the stomach leaks up into the oesophagus (gullet) and causes symptoms such as heartburn and an unpleasant taste in the back of the mouth.
- Trial name
- NCT03390634
- Testing
- Gastroesophageal reflux symptoms questionnaires
- Where
- United Kingdom
- Volunteers
- 343 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Gastric Feeding Tube, Blood Gas Monitoring, Transcutaneous
End-Tidal CO2 (etCO2) and pH in the Correct Naso-gastric Tube Placement
The laying of a naso-gastric tube is an extremely common event in intensive medicine; although standard naso-gastric tube laying is performed at the patient's bedside, this procedure is not without risk.
- Conditions
- Gastric Feeding Tube, Blood Gas Monitoring, Transcutaneous, pH
- Trial name
- NGT (NCT03934515)
- Testing
- etCO2, pH
- Where
- Switzerland
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Clinica Luganese Moncucco
Complication of Surgical Procedure, Complication of Anesthesia
Wireless Assessment of Respiratory and Circulatory Distress in Vascular Surgical Patients - An Observational Study
Vascular postsurgical patients have a high risk of morbidity and mortality. On top of that, patients undergoing vascular surgery usually have a high burden of comorbidities.
- Conditions
- Complication of Surgical Procedure, Complication of Anesthesia, Respiratory Complication, Circulatory; Complications
- Trial name
- WARD-VASC (NCT04628858)
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Eske Kvanner Aasvang
Energy Intake, Metabolism
Identifying Wearable Biomarkers to Monitor Dietary Intake
Background: Measuring what people eat is a challenge in nutrition research. Traditional methods, like food diaries, rely on self-reporting of individuals, and suffer from poor accuracy and recall bias.
- Conditions
- Energy Intake, Metabolism, Digestion, Wearables
- Trial name
- FoodSense (NCT06398340)
- Testing
- High Calorie Meal Intervention, Low Calorie Meal Intervention
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Healthy Volunteers
Showers and Stress
The study investigates whether repeated exposure to cold showers can improve the ability to cope with and respond to stress. In particular, it examines both the psychophysiological effects of cold showers and the role of…
- Trial name
- S A S (NCT07611422)
- Testing
- Positive expectation about the effects of cold and warm showers, No expectation regarding the exposure to cold water and/or to warm showers
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Blood Oxygen Desaturations, Sleep-Disordered Breathing
Assessment of the Accuracy of the Non-invasive Wireless Armband Gabi Baby Band for Continuous Vital Parameters Monitoring in Infants and Young Children
During a polysomnography test (PSG) previously prescribed by a physician, the patient also wears the Gaby Baby Band (GBB) during an entire night of sleep.
- Trial name
- WAGSC1 (NCT04886583)
- Testing
- Gabi Baby Band
- Where
- 3 sites in Belgium
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Gabi SmartCare
Perioperative Care, Fluid Therapy
Paired Comparison of SVV and PVI Accuracy
This study will compare two operating-room monitors-stroke volume variation (SVV, from the arterial line) and the Pleth Variability Index (PVI, from the pulse oximeter)-to see which one more accurately predicts whether giving a…
- Conditions
- Perioperative Care, Fluid Therapy, Monitoring, Physiologic, Hemodynamics
- Trial name
- NCT07260890
- Testing
- Stroke Volume Variation (SVV) monitoring, Pleth Variability Index (PVI) monitoring
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Medical Device, User-Computer Interface
VitalPAD: an Intelligent Monitoring and Communication Device to Optimize Safety in the PICU
The VitalPAD is a unified, portable and intelligent device that integrates information from multiple patient monitors, mechanical ventilators, infusion pumps and clinical information systems on a mobile platform.
- Conditions
- Medical Device, User-Computer Interface, Critical Care, Physiologic Monitoring
- Trial name
- NCT02970903
- Testing
- VitalPAD, Traditional tools
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Epilepsy, Tonic-Clonic
EpiWatch: Evaluation of a Non-EEG Physiological Signal Based Seizure Monitoring System
To demonstrate the safety and effectiveness of the EpiWatch device in identifying tonic-clonic (TC) seizures, notifying a third-party of TC seizure occurrence, and collecting non-EEG physiological data for subsequent review…
- Trial name
- NCT05059002
- Testing
- Physiological signal monitoring and seizure detection
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- EpiWatch, Inc.
Subarachnoid Hemorrhage, Aneurysmal, Brain Injuries, Traumatic
Prospective Observational Multimodal Neuromonitoring in Adult NSICU Patients
This is a prospective observational cohort study of adult patients admitted to the Neurosciences Intensive Care Unit (NSICU) at UT Southwestern Medical Center.
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Brain Injuries, Traumatic, Cerebral Hemorrhage, Ischemic Stroke
- Trial name
- NCT07577713
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Texas Southwestern Medical Center
Infant, Newborn, Diseases, Bowel Sounds
Detection of Infant GastrointEstinal Activity Using Sound Technology
This pilot study aims to evaluate the feasibility and safety of continuous bowel sound monitoring in healthy term newborn infants using a novel wireless acoustic monitoring system.
- Conditions
- Infant, Newborn, Diseases, Bowel Sounds, Physiologic Monitoring, Wearable Sensors
- Trial name
- DIGEST (NCT07743216)
- Volunteers
- 10 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
PHYSIOLOGICAL PHENOMENA, Homeostasis
Truway Whole-Body Digital Twin and Physiologic Resilience Study (TRU-OMNIBODY)
TRU-OMNIBODY is a prospective observational study designed to develop and independently validate a research-only whole-body digital twin.
- Conditions
- PHYSIOLOGICAL PHENOMENA, Homeostasis, Physical Functional Performance, Cardiorespiratory Fitness
- Trial name
- TRU-OMNIBODY (NCT07805044)
- Testing
- Standardized Physiologic Resilience Challenge, Multimodal Whole-Body Physiologic Monitoring, Research-Only Whole-Body Digital Twin Analysis
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Pediatric ALL, Congenital Heart Disease
Virtual Remote Physiological Monitoring Program of Children With Heart Disease
Infants and children with heart conditions require treatment in children's hospitals that are typically located in large cities.
- Conditions
- Pediatric ALL, Congenital Heart Disease, Single-ventricle, Biventricular Congestive Heart Failure
- Trial name
- NCT05034354
- Testing
- Remote physiological monitoring
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- University of Alberta
Cerebral Palsy (CP), Intraventricular Hemorrhage Neonatal
Intelligent Physiological Monitoring to Predict Preterm Brain Injury
Cerebral palsy (CP) remains prevalent among very (28-31 weeks) and extremely (<28 weeks) preterm infants. Prematurity-related brain injuries (high-grade intraventricular haemorrhage, IVH or periventricular leukomalacia, PVL)…
- Conditions
- Cerebral Palsy (CP), Intraventricular Hemorrhage Neonatal, Periventricular Leukomalacia, Neurodevelopmental Delay
- Trial name
- AI4NICU (NCT07880431)
- Testing
- EEG, NIRS
- Where
- Ireland
- Volunteers
- 413 people
- Sponsor
- University College Cork