Clinical trials: Montreal Cognitive Assessment (MoCA)
Postoperative Delirium, Postoperative Cognitive Dysfunction
Greek Validation of ACE III Test in Perioperative Patients
Postoperative neurocognitive disorders, including postoperative delirium (POD) and postoperaive cognitive dysfunction (POCD), are common complications of perioperative neurocognition in elderly patients undergoing surgery.
- Trial name
- NCT04312516
- Where
- Greece
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Substance-Related Disorders, Substance Use Disorder
Sleep Architecture, Cognitive Function, and Quality of Life During Early Recovery From Substance Use Disorder
This prospective cohort study investigates how sleep disturbances affect cognitive recovery and quality of life during early recovery from substance use disorder (SUD).
- Conditions
- Substance-Related Disorders, Substance Use Disorder, Sleep Wake Disorders, Cognitive Dysfunction
- Trial name
- NCT07852052
- Volunteers
- 34 people
- Sponsor
- Assiut University
Cognitive Impairment, Cognitive Decline
Normative Values for the German Version of the Montreal Cognitive Assessment (MoCA)
This observational cohort study in healthy volunteers establishes normative data for the German version of the Montreal Cognitive Assessment (MoCA) and investigates the possible impacts of demographics on the MoCA total score.
- Conditions
- Cognitive Impairment, Cognitive Decline, Cognition Disorders, Cognitive Symptom
- Trial name
- MoCA-Norm (NCT03246269)
- Testing
- MoCA
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Andreas Monsch
Cognitive Impairment, Older People--Abuse of
Pre- and Post TAVI Cognitive Functioning and Intraoperative Carotid Flow Measurements
Purpose: 1. Measuring and optimize the usability of the BAMCOG (games to measure cognitive functioning) 2. Concurrent validation of BAMCOG with MoCA to see if BAMCOG can serve as a monitoring instrument/screener 3.
- Conditions
- Cognitive Impairment, Older People--Abuse of, Aortic Stenosis, Severe
- Trial name
- NCT05813353
- Where
- Netherlands
- Volunteers
- 54 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Chronic Kidney Diseases
Eye-Brain-Kidney in CKD
The goal of this observational study is to learn about the interaction between the eyes, brain, and kidneys in adult patients with Chronic Kidney Disease (CKD).
- Trial name
- NCT07358572
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Beijing Friendship Hospital
Mild Cognitive Impairment, Alzheimer Disease
Screening for Anti-amyloid Treatment Eligibility Using Digital Cognition and Blood-based Biomarkers
This study evaluates a diagnostic screening solution for Alzheimer's disease (AD) using digital cognitive assessments and blood-based biomarkers.
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease, Dementia
- Trial name
- NCT07041450
- Testing
- Digital MoCA, XpressO, MoCA
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- MoCA Clinic and Institute
Focal Epilepsy, Cognitive Impairment
Butylphthalide for Cognitive Impairment in Elderly Patients With Focal Epilepsy
This is a multicenter, randomized, double-blind, placebo-controlled trial evaluating the safety and efficacy of butylphthalide soft capsules for treating cognitive impairment in elderly patients with focal epilepsy.
- Trial name
- NCT07193277
- Testing
- Butylphthalide
- Where
- China
- Volunteers
- 220 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Cognitive Deficits, Alzheimer Disease
Acupuncture Treatment for Improving Alzheimer's Dementia
Evaluate cognitive improvement pre amd post acupuncture treatment in patients with probable alzheimer's dementia as measured by MOCA score and also per form A( measure of patient's personal information). Also caregiver input.
- Trial name
- NCT04064021
- Testing
- Acupunture
- Sponsor
- N & S Neurology Center, A Medical Group, Inc
Aging Problems
Evaluation of the EEG Connectivity Using Predominant Dexmedetomidine as Anesthetic in Fragile Brains
Elderly brains that present a lower intrinsic cortical activity are very dependent on arousal feeding. In these patients, a strong blockade of afferences generates a synchronic state with a high tendency to sleep.
- Trial name
- BaseDexmed (NCT05425069)
- Testing
- Comparison MoCA test and EEG connectivity pre, intra and postoperative between groups P vs D-P
- Where
- Chile
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad del Desarrollo
Cognitive Dysfunction, Epilepsy
The Effect of Cognitive Rehabilitation on Epileptic Pateints Under Treatment
It is clear that studies on cognitive rehabilitation in epilepsy patients mostly focus on patients undergoing epilepsy surgery and are largely classified according to the type of epilepsy.
- Trial name
- NCT06643559
- Testing
- cognitive rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital
Mild Cognitive Impairment
The Montreal Cognitive Assessment as a Screening Tool for Preoperative Mild Cognitive Impairment in Geriatric Patients
This is a prospective, double-blinded, control trial. The Montreal Cognitive Assessment is used to screen preoperative mild cognitive impairment in 582 consecutive geriatric patients, scheduled for general, vascular or urological…
- Trial name
- MoCA (NCT01496222)
- Where
- Thailand
- Volunteers
- 582 people
- Sponsor
- Mahidol University
Behavioral and Psychological Symptoms of Dementia, Dementia
Validation and Reliability of the Turkish Version of the Montreal Cognitive Assessment-Basic (MoCA-B) in Individuals With Low Educational Level
This study aimed to evaluate the validity, reliability, and diagnostic accuracy of the Turkish version of MoCA-B in distinguishing healthy controls, mild cognitive impairment (MCI), and dementia patients within a low-education…
- Conditions
- Behavioral and Psychological Symptoms of Dementia, Dementia, Dementia (Diagnosis), Dementia Alzheimer Type
- Trial name
- MoCA-B Turkish (NCT07630688)
- Where
- Turkey (Türkiye)
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Antalya Training and Research Hospital
Inguinal Hernia Unilateral, Delayed Neurocognitive Recovery
Preemptive IV Ibuprofen for Neurocognitive Recovery and Analgesic Needs After Inguinal Hernia Surgery
The primary objective of this study is to evaluate the effects of preemptive intravenous ibuprofen administration on delayed neurocognitive recovery (dNCR), postoperative pain management, and the overall quality of recovery in…
- Conditions
- Inguinal Hernia Unilateral, Delayed Neurocognitive Recovery, Postoperative Pain, Neuroinflammation
- Trial name
- IBU-COG (NCT07424001)
- Testing
- Ibuprofen (400 mg x 4)
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Mehmet Çiğdem
ATRIAL FIBRILLATION
Blinded Randomized Trial of Anticoagulation to Prevent Ischemic Stroke and Neurocognitive Impairment in AF
This is a prospective, multicenter, randomized, double-blinded clinical trial exploring the efficacy and safety of rivaroxaban as compared to standard of care in reducing stroke, transient ischemic attack (TIA) and neurocognitive…
- Trial name
- BRAIN-AF (NCT02387229)
- Testing
- Rivaroxaban, standard of care
- Where
- 41 sites in Canada
- Volunteers
- 1,238 people
- Sponsor
- Montreal Heart Institute
Meningioma
Magnesium and Intraoperative Blood Loss in Meningioma Surgery
Meningioma is the most common central nervous system tumor and craniotomy with tumor removal was associated with moderate blood loss and blood transfusion.
- Trial name
- NCT03558516
- Testing
- Magnesium group, Normal saline group
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Mahidol University
Neurocognitive Disorder, Robotic Assisted Laparoscopic Radical Prostatectomy
The Effect of Steep Trendelenburg Position on Neurocognitive Functions in Robotic Radical Prostatectomy Cases
The aim of this study is to evaluate the effects of the steep Trendelenburg position in robotic prostatectomy cases, where anesthesia depth is monitored using BIS and cerebral perfusion is tracked with NIRS, and to determine the…
- Conditions
- Neurocognitive Disorder, Robotic Assisted Laparoscopic Radical Prostatectomy, Near Infrared Spectroscopy
- Trial name
- NCT06869304
- Testing
- Montreal Cognitive Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Cognitive Function
Nutrilite Memory Builder on the Improvement of Cognitive Function
Its a randomized controlled trial, to evaluate the effect of NUTRILITE Memory Builder on the improvement of cognitive function in middle-aged and elderly people.
- Trial name
- NCT05591885
- Testing
- Study product group (Nutrilite Memory Builder)
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amway (China) R&D Center
Hyperoxia, Normoxic
Intraoperative Oxygen Concentration and Neurocognition After Cardiac Surgery
This is a randomized, prospective controlled trial in patients undergoing cardiac surgery, specifically on-pump coronary artery bypass grafting, comparing level of administered oxygen and partial pressure of arterial oxygen in…
- Conditions
- Hyperoxia, Normoxic, Delirium
- Trial name
- NCT02591589
- Testing
- Normoxic oxygenation, Hyperoxic oxygenation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Beth Israel Deaconess Medical Center
Traumatic Brain Injury, Acquired Brain Injury
Comparative Utility of Clinical Balance Measures in Traumatic Brain Injury
The purpose of this research study is to investigate how useful three balance tests are in predicting fall risk in the individual with traumatic brain injury (TBI).
- Conditions
- Traumatic Brain Injury, Acquired Brain Injury, Accidental Falls
- Trial name
- NCT02696538
- Testing
- Functional Gait Assessment, mini-Balance Evaluation Systems Test, Berg Balance Scale
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston
Benign Prostatic Hyperplasia, Cognitive Functions
Comparative Neurocognitive Outcomes Following Prostate Surgery
This prospective observational cohort study aims to evaluate postoperative cognitive outcomes in patients undergoing surgical treatment for benign prostatic hyperplasia (BPH).
- Trial name
- NCT07468084
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Cengiz Canakci, MD