Clinical trials: Mood (Psychological Function)
Bipolar Disorder, Bipolar and Related Disorders
Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders
This study is testing whether a type of gentle brain stimulation, combined with computer-based brain training exercises, can help improve thinking skills in Veterans with bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide
- Trial name
- TACTIC-BD (NCT07845409)
- Testing
- Soterix 1x1 tES mini-CT
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Hypoactive Sexual Desire Disorder (HSDD)
Stress Hormones, Mood and Women's Sexual Desire (MODEST)
Women with Hypoactive sexual desire disorder (HSDD) have all measures of testosterone activity comparable to controls but lower levels of dehydroepiandrosterone (DHEA).
- Trial name
- MODEST (NCT01702818)
- Where
- Canada
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Overweight, Mood
Effects of a Ketogenic Diet on Psychological Outcomes
The aim of the study is to investigate how glycemia and ketonemia variations during three different diet protocols: a ketogenic diet without any restriction on calories intake (KD), a calorie-restricted ketogenic-mediterranean…
- Conditions
- Overweight, Mood, Appetitive Behavior
- Trial name
- NCT04086498
- Testing
- Mediterranean diet, KEMEPHY, KD
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Padova
Major Depressive Disorder (MDD)
Effects Of Antidepressants On Sexual Functioning In Adults
This study will evaluate the effects of two antidepression medications on sexual functioning.
- Trial name
- NCT00051272
- Testing
- Extended-release Bupropion Hydrochloride
- Where
- 24 sites in United States
- Volunteers
- 425 people
- Sponsor
- GlaxoSmithKline
Pain, Fatigue
Kinesio Taping and Foot Massage for Post-Cesarean Recovery
After a cesarean section, postpartum women may experience pain, fatigue, and various negative mood disturbances. These effects pose a significant public health concern by threatening both maternal and infant health.
- Conditions
- Pain, Fatigue, Mood (Psychological Function), Postpartum Women
- Trial name
- NCT06811285
- Testing
- Kinesiological Taping, Foot Massage Group
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Uşak University
Emotional Processing and Cognitive Function in Perimenopausal Women Experiencing Cognitive Perturbations, Perimenopause
Probiotic Intake and Perimenopausal Psychological Assessments
Recent evidence suggests multi-strain probiotics containing Lactobacillus rhamnosus and Bifidobacterium longum have been found to enhance emotional processing and reduce salience to negative cues in studies involving people with…
- Conditions
- Emotional Processing and Cognitive Function in Perimenopausal Women Experiencing Cognitive Perturbations, Perimenopause, Perimenopause-Related Depression, Perimenopausal Women
- Trial name
- PIPPA (NCT07590999)
- Testing
- Multi-strain probiotic
- Where
- United Kingdom
- Volunteers
- 106 people
- Sponsor
- University of Oxford
Bipolar Disorder, Mental Health
Reproductive Function and Mood in Women With Bipolar Disorder
This study will determine the effect of medication for bipolar disorder on the reproductive function and whether mood changes occur during the menstrual cycle in women with bipolar disorder.
- Trial name
- NCT00183352
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Stanford University
Hypoactive Sexual Desire Disorder, Female Sexual Arousal Disorder
Effects of Early Abuse on Adult Intimate Relationships
This study is designed to help us better understand the factors that affect the sexual lives of women who have been sexually mistreated during childhood.
- Conditions
- Hypoactive Sexual Desire Disorder, Female Sexual Arousal Disorder, Female Orgasmic Disorder, Major Depressive Disorder
- Trial name
- NCT01803802
- Testing
- Expressive writing
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Ventricular Arrhythmia, Implantable Cardioverter Defibrillator
Positive Therapy for Autonomic Function & Mood in ICD Patients
The purpose of this 2-group randomized clinical trial is to: 1) examine the feasibility and acceptability of a 3-month positive-emotion focused therapy (Quality of Life Therapy) modified specifically for patients with implantable…
- Trial name
- PAM-ICD (NCT02088619)
- Testing
- Quality of Life Therapy (QOLT), Heart Healthy Education (HHE)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Medical University of South Carolina
Mood (Psychological Function)
Effects of Horticultural Therapy on Asian Elderly' Mental Health
The objective of this study is to determine whether horticultural therapy would improve the psychological well-being of the older adults.
- Trial name
- HTRCT (NCT02495194)
- Testing
- Horticultural Therapy
- Where
- Singapore
- Volunteers
- 69 people
- Sponsor
- National University of Singapore
Mental Health
An Evaluation of Innerview™, a Web-based Tool to Support the Integration of Mental Health in the Primary Care Setting
Innerview can address some of the challenges of integrating mental health and primary care by accurately and reliably collecting mental health evidence and activities directly from patients, and then organizing and automating…
- Trial name
- NCT02025647
- Where
- 5 sites in United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Pearson/Clinical Assessment
Mood (Psychological Function), Well Being
Psilocybin Efficacy With or Without Pimavanserin Pretreatment
Twenty healthy adults (≥21 years old) will be enrolled to evaluate the efficacy of a single oral dose of psilocybin (25 mg) administered with or without pretreatment using oral pimavanserin (34 mg) or placebo.
- Conditions
- Mood (Psychological Function), Well Being, Mood, Healthy
- Trial name
- PRISMatic (NCT07610135)
- Testing
- Psilocybin, Pimavanserin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Stress, Physiological, Stress, Emotional
Psychophysiological Effects of Controlled Respiration and Mindfulness
The investigators aim to understand the effectiveness of 3 types of breathwork exercises and a mindfulness meditation control on improving psychological and physiological measures of wellbeing.
- Conditions
- Stress, Physiological, Stress, Emotional, Insomnia
- Trial name
- PECRM (NCT05304000)
- Testing
- Mindfulness Meditation, Cyclic Sighing Breathing, Box Breathing
- Where
- 2 sites in United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Stanford University
Intrinsic Capacity, Frailty
Project ICOPE Brazil: Assessment of Intrinsic Capacity in Brazilian Older Adults
The ICOPE Brazil study aims to understand aging trajectories in Brazil, especially healthy aging trends based on intrinsic capacity, a collective of mental and physical capacities one may have to maintain their functional ability…
- Conditions
- Intrinsic Capacity, Frailty, Aging, Healthy Aging
- Trial name
- ICOPE-BR (NCT06968702)
- Volunteers
- 3,838 people
- Sponsor
- University of Sao Paulo
Bereavement, Depressive Disorder
Consequences of Conjugal Bereavement in Adults
Bereavement refers to the expected reactions and sadness associated with the loss of a loved one. It has been reported that the loss of a spouse is rated as the major life stressor among survivors of varying ages and diverse…
- Conditions
- Bereavement, Depressive Disorder, Immunologic Disease, Mental Disorder
- Trial name
- NCT00001659
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Sleep, Sleep Restriction
Performance, Mood, and Brain and Metabolic Functions During Different Sleep Schedules
This proposed project will investigate whether a variable or a stable sleep schedule will be more effective in minimizing neurobehavioural and metabolic deficits when total sleep opportunity across two weeks is below the…
- Trial name
- STAVAR (NCT04731662)
- Testing
- Short sleep, Variable short sleep
- Where
- Singapore
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Major Depressive Disorder
Treatment Outcome in Major Depressive Disorder
Major Depressive Disorder (MDD) is one of the most severe and frequently occurring brain disorders worldwide. It has been linked to serotonergic dysfunction, sexual dysfunction, vulnerability to stress and neuro-inflammation.
- Trial name
- NCT02869035
- Testing
- Escitalopram, Duloxetine
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Psychological Distress, Post Partum Depression
Impact of Mothers Touch Program on Women's Psychological Functioning
The study investigates the effect of the Mothers Touch program on the psychological well-being of new mothers following 5 weeks of child birth.
- Conditions
- Psychological Distress, Post Partum Depression, Mood
- Trial name
- NCT03703219
- Testing
- Mothers Touch Program
- Where
- India
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- NMP Medical Research Institute
Healthy, Adolescent
Physical Activity on Motor Competence, Cognitive Function and Mood in Adolescents
The study aimed to determine the effect of coordinative-based physical activity practices on motor competence, cognitive function and mood levels of adolescent boys.
- Trial name
- NCT07111780
- Testing
- "Coordinative-Based Physical Activity Practices" training group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Postpartum Depression, Posttraumatic Stress Disorder
Intervention for IPV-exposed Pregnant Women
The overarching goal of the proposed project is to evaluate a randomized clinical trial of the Pregnant Moms' Empowerment Program aimed at detecting its effects on maternal mental health, re-victimization, parenting sensitivity…
- Conditions
- Postpartum Depression, Posttraumatic Stress Disorder, Infant Behavior, Violence
- Trial name
- NCT04068662
- Testing
- Pregnant Moms' Empowerment Program, Nondirective Support Group
- Where
- 2 sites in United States
- Volunteers
- 424 people
- Sponsor
- University of Notre Dame