Clinical trials: Mood (Psychological Function)
Cognitive Change, Stress, Psychological
Acute and Chronic Effects of Avena Sativa on Cognition and Stress
The flavanoid and terpene phytochemicals present in wild green oat interact with multiple mechanisms relevant to brain function; including those which would modulate cognition and stress.
- Conditions
- Cognitive Change, Stress, Psychological, Mood
- Trial name
- NCT03689348
- Testing
- Avena sativa
- Where
- United Kingdom
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Bipolar Disorder
Effects of an Integrative Psychological Program in Bipolar Disorder
Bipolar disorder is related to a high level of personal, familial, social and economic burden. There is a need for feasible adjunctive psychological interventions to use in clinical practice as a complement of pharmacotherapy to…
- Trial name
- NCT04031560
- Testing
- Integrative treatment
- Where
- Spain
- Volunteers
- 124 people
- Sponsor
- Consorcio Centro de Investigación Biomédica en Red (CIBER)
Mood, Poor Quality Sleep
The Effects of a Multi-ingredient Night-time Tea on Sleep Quality, Wellbeing and Markers of Immune Function
The aim of the study is to determine whether a night-time tea can improve subjective sleep quality in healthy sleepers and self-reported poor sleepers, compared to a control drink.
- Conditions
- Mood, Poor Quality Sleep, Good Sleep Habit, Sleep
- Trial name
- NCT05478980
- Testing
- Night Time Tea, Control Tea
- Where
- United Kingdom
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Metacognitive Capacities
Psychological Factors In The Treatment Of Bipolar Mood Disorders
The aim of this study is to trial an intervention targeting potential deficits in an individual's ability to form, and reflect upon, ideas about themselves and others (known as metacognitive capacities), specifically in relation…
- Trial name
- NCT03266679
- Testing
- Metacognitive Reflection and Insight Therapy - Adapted
- Where
- 2 sites in Australia
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Queensland University of Technology
Mood (Psychological Function)
Effect of Relora Supplement on Anxiety, Cognitive Performance & Mood Tested After Induced Stress
The present randomized, double-blind, placebo-controlled crossover trial aims to evaluate the effects of Relora supplementation on responses to induced stress produced by a combination of cognitive and physiologic stressors in…
- Trial name
- NCT02734251
- Testing
- Relora
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- InterHealth Nutraceuticals, Inc.
Wounds and Injuries, Physical Activity
Swiss Army Physical Fitness Training
The purpose of this study is to determine whether the new sport concept of the Swiss Armed Forces influences the physical and psychological fitness of the recruits.
- Conditions
- Wounds and Injuries, Physical Activity, Mood (Psychological Function), Motivation
- Trial name
- SAFT (NCT02570295)
- Testing
- Swiss Army Physical Fitness Training
- Where
- Switzerland
- Volunteers
- 722 people
- Sponsor
- Swiss Federal Institute of Sport Magglingen
Major Depressive Disorder
Depression, Epinephrine, and Platelet Function
Men and women who have suffered sexual and/or physical abuse before the age of 12 are at increased risk for anxiety and mood disorders, other serious psychiatric disorders, and likely medical illnesses.
- Trial name
- NCT00166114
- Testing
- Escitalopram, Desipramine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Emory University
Stress
Natural Modulators of Immune Function and Mood
The objective of this proposal is to recruit 20 healthy subjects per ingredient arm (5 arms x 20 subjects; N= 120 total) to participate in a research study investigating the effects of dietary supplementation for one-month with…
- Trial name
- NCT05508529
- Testing
- Chaga Mushroom, Algae Extract, Black Cumin Seed Oil
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- 3 Waves Wellness
Depression
Clinical and Economic Evaluation of Neurocognitively-Enhanced Online Cognitive Behavioural Therapy
To evaluate the clinical efficacy of online cognitive behavioural therapy supplemented with online neurocognitive remediation therapy to improve mood and cognition, decrease relapse rates and optimise work and occupational…
- Trial name
- OPTM (NCT04010643)
- Testing
- online cognitive behavioural therapy, online neurocognitive remediation therapy
- Where
- Denmark
- Volunteers
- 134 people
- Sponsor
- University of Southern Denmark
Hydration Status
Hydrate Heroes for Improving Brain Function & Mood
The primary goal of this 12-week randomized controlled study is to evaluate whether daily use of Hydrate Heroes results in measurable improvements in brain activity, mental health, and performance on cognitive tasks.
- Trial name
- NCT07241260
- Testing
- Hydrate Heroes (6 packets), Hydrate Heroes (3 packets)
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Cognitive Change, Stress
Acute Effects of Mango Leaf Extract (Zynamite®) on Cognitive Function, Mood and Stress
This study aims to assess the effects of a single dose of Zynamite® on performance across a number of cognitive domains (attention, working memory, episodic memory, executive function), as well as during a period of cognitively…
- Trial name
- MLE-ZYN (NCT04299217)
- Testing
- Zynamite®
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Psychological Distress, Psychological Well-being
Two Sessions of Coach-Delivered Core Transformation for Distress and Well-Being
The goal of this study is to learn if Core Transformation, a guided coaching process, lowers psychological distress in adults. It will also look at well-being, daily functioning, and whether any changes last over time.
- Trial name
- NCT07879196
- Testing
- Core Transformation Process
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Andreas NLP (Legal Entity - Real People Press)
Aging
Probiotic on Psychological and Cognitive Effects
This study will determine whether supplementation of probiotic Lactobacillus Rhamnosus GG improves psychological status in middle age and older adults through a 12-week, randomized, double-blind, placebo-controlled clinical…
- Trial name
- NCT03080818
- Testing
- Probiotic - Lactobacillus Rhamnosus GG
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kent State University
Major Depressive Disorder (MDD)
Effects of Antidepressants on Sexual Functioning
The purpose of this trial is to study the effects of two depression medications on sexual functioning.
- Trial name
- NCT00051259
- Testing
- Extended-Release Bupropion Hydrochloride
- Where
- 23 sites in United States
- Volunteers
- 420 people
- Sponsor
- GlaxoSmithKline
Dementia, Behavioral and Psychological Symptoms of Dementia (BPSD)
Testing the Implementation of EIT-4-BPSD
This pragmatic trial focuses on implementation of an evidence based process to increase person-centered management of behavioral and psychological symptoms of dementia (BPSD) in nursing homes, referred to as EIT-4-BPSD.
- Trial name
- EIT-4_BPSD (NCT03014570)
- Testing
- EIT-4-BPSD, Education-only Control
- Where
- United States
- Volunteers
- 553 people
- Sponsor
- University of Maryland, Baltimore
Major Depressive Disorder
Does Fluoxetine Have an Effect on the CNS CRF Systems in Women Abused in Childhood?
The primary objective of this project is to determine whether treatment with the SSRI, fluoxetine versus placebo reverses alterations in the central CRF system induced by early life stress experiences (i.e.
- Trial name
- NCT00208897
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Emory University
ADHD, BD
A Novel Psychological Intervention for Adults With Bipolar Disorder and Attention Deficit Hyperactivity Disorder Comorbidity (VECTOR)
Cognitive dysfunctions are present in Bipolar Disorder (BD) and Attention Deficit Hyperactivity Disorder (ADHD) and may negatively impact psychosocial functioning.
- Trial name
- VECTOR (NCT07039903)
- Testing
- Cognitive behavioral therapy (CBT) + Functional Remediation (FR)
- Where
- Spain
- Volunteers
- 68 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Respiratory Tract Infections (RTI), Mucosal Immunity
Fermented Milk Drink With Lacticaseibacillus Paracasei Strain Shirota Helps Triathletes With Cold-Like Symptoms Before and After a Race
This study aims to evaluate whether a fermented milk drink containing the probiotic strain Lacticaseibacillus paracasei strain Shirota (LCS), commonly found in Yakult®, can help reduce upper respiratory symptoms in triathletes…
- Conditions
- Respiratory Tract Infections (RTI), Mucosal Immunity, Systemic Inflammation, Depressive Disorder
- Trial name
- NCT06970964
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Major Depressive Disorder
Reward Function and Therapy for Late-Life Depression
The goal of this study is to learn about changes in the brain that occur during Engage, a psychotherapy for depression in older adults, and how they may differ from changes that occur during supportive therapy.
- Trial name
- NCT03688139
- Testing
- Engage Therapy, Supportive Therapy
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Weill Medical College of Cornell University
Stress, Psychological Factors
Body Awareness Therapy in High Stressed Young Adults: Effects on Function, Balance, Sleep and Mood
Body Awareness Therapy (BAT) is a holistic approach to human movement that considers the physical, physiological, psychological, and existential aspects of human existence.
- Conditions
- Stress, Psychological Factors, Sleep, Postural Balance
- Trial name
- NCT07045792
- Testing
- Body Awareness Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University