Clinical trials: Mood Change
Obesity, Eating Behavior
The Effects of Chia on Overweight/Obese Women
The purpose of the study is to examine the effect of chia seed consumption on body composition, blood pressure, blood glucose, satiety, mood, joint pain, and dietary displacement in overweight and obese females (18-45years).
- Conditions
- Obesity, Eating Behavior, Mood, Glucose
- Trial name
- NCT03233906
- Testing
- Chia Seeds- Salvia Hispanica
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- California State Polytechnic University, Pomona
Weight Loss, Gut Microbiome
Low Sugar Protein Pacing, Intermittent Fasting Diet in Men and Women
This study will systematically quantify the effects of protein pacing and intermittent fasting (P-IF) on total and regional (abdominal) body composition (lean mass and fat mass), blood glucose and lipids, and anti-aging…
- Conditions
- Weight Loss, Gut Microbiome, Anti-Aging
- Trial name
- NCT04327141
- Testing
- P-IF, HH
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Mood, Cognitive Change
OxPALM: Oxford Study on Probiotics and Low Mood
Probiotics are live bacteria which have been suggested to have beneficial effects not only on gut function but also on psychological and cognitive functioning.
- Trial name
- NCT03801655
- Testing
- Bio-Kult
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Nicotine Dependence
Multiple Cigarette Induced Changes in Hormone Function, Mood States and Behavior
The proposed clinical studies will analyze the interactions between nicotine, alterations in endocrine hormones, mood and cardiovascular measures. They also intend to examine the contribution of gender and menstrual cycle phase.
- Trial name
- NCT01636310
- Testing
- Nicotine
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Cognitive Change, Mood
Effect of PeakATP on Mood, Reaction Time and Cognition
Oral ATP disodium (adenosine 5'- triphosphate disodium) is a commercially available product available alone and as a constituent in a number of sports supplements that is purported to maintain ATP levels and improve performance…
- Trial name
- NCT05100589
- Testing
- PeakATP
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Major Depressive Disorder, Cognitive Change
THINC-it Vortioxetine - Sensitivity to Change
The purpose of this study is to evaluate the sensitivity of the THINC-it tool, in measuring change in cognitive deficits in individuals with MDD after receiving vortioxetine.
- Trial name
- NCT03053362
- Testing
- Vortioxetine, THINC-it Tool
- Where
- Canada
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Brain and Cognition Discovery Foundation
Cognitive Change, Mood
Acute and Chronic Effects of Ecologic Barrier© on Mood and Cognition
This study aims to investigate the acute and chronic effects of an 8 week probiotic intervention (Ecologic Barrier©) on mood and cognitive outcomes in healthy adults.
- Trial name
- ProCog (NCT04951687)
- Testing
- Ecologic Barrier©
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Reading
Cognitive Change, Mood Change
Cognitive Effects of Sage in Healthy Humans
Extracts of sage and polyphenols have separately been reported to interact with central nervous system (CNS) mechanisms relevant to cognitive performance but, to date, no trial has combined these interventions.
- Trial name
- NCT03695003
- Testing
- Cognivia
- Where
- United Kingdom
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Nicotine Dependence
Smoked Nicotine Induced Changes in Hormone Function, Mood States and Behaviors
The proposed clinical studies will evaluate the acute effects of nicotine on the hypothalamic-pituitary-gonadal axis in women to test the hypothesis that nicotine alters gonadal steroid hormones, and/or disrupts feedback…
- Trial name
- NCT01636323
- Testing
- Nicotine
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Cognitive Change, Mood
Neurological, Inflammatory and Metabolic Effects of Acute Mushroom Intervention in Older Adults
This randomized crossover trial (RCT) investigates the acute effect (over a 6-hour period) of a meal containing varying serving sizes (doses) of freeze-dried oyster mushroom powder, on the cognitive behaviour and markers of…
- Conditions
- Cognitive Change, Mood, Metabolism, Inflammatory Response
- Trial name
- OYSACO (NCT05594329)
- Testing
- Instant noodle soup containing containing the equivalent of 2 servings (18.78g) of powdered Pleurotus oyster mushroom., Instant noodle soup containing containing the equivalent of 1 serving (9.39g) of powdered Pleurotus oyster mushroom., Instant noodle soup containing containing the equivalent of 0.5 serving (4.70g) of powdered Pleurotus oyster mushroom.
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Reading
Postpartum Depression, Postpartum Anxiety
The Maternal Well-Being Study
This project aims to understand the local feasibility and acceptability of MamaMeals (a home-delivered nutritious, postpartum meal delivery program) and MamaMatters (a moderated social media-based peer support group) among…
- Conditions
- Postpartum Depression, Postpartum Anxiety, Weight Retention, Postpartum, Nutritional and Metabolic Diseases
- Trial name
- MWB (NCT05484999)
- Testing
- Meals, Meals + Social Support, Control
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Validate STRIDE Exercise Intervention in Sedentary Individuals, Increase Positive Attitudes, Perceived Normative Support, Self-efficacy, and Intentions
Mediators and Moderators of Exercise Behavior Change
Rates of cancer and cardiovascular disease have shown very little improvement over the past two decades, and the incidence of Type II diabetes mellitus is increasing at an alarming rate.
- Conditions
- Validate STRIDE Exercise Intervention in Sedentary Individuals, Increase Positive Attitudes, Perceived Normative Support, Self-efficacy, and Intentions, Increase Self-reported Physical Activity
- Trial name
- COSTRIDE (NCT01091857)
- Testing
- STRIDE
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Major Depressive Disorder
Intradermal Acupuncture Based on Changes in Biological Specificity of Acupoints for Major Depressive Disorder
Acupoints are the stimulus points and reactive points for acupuncture to treat diseases. Therefore, this study is designed to detect the pain threshold and temperature of biological specificities of acupoints in healthy control…
- Trial name
- NCT05524519
- Testing
- Basic treatment, PSA, TSA
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Bipolar Disorder
Culturally Adapted Psychoeducation (CaPE) for Bipolar Disorders in Nigeria
Bipolar disorders are chronic mental health disorders that often result in functional impairment, constituting a significant disease burden.
- Trial name
- NCT05721196
- Testing
- Culturally adapted Psychoeducation (CaPE), Treatment as Usual (TaU)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nottingham Trent University
Mental Processes, Cognitive Change
The Effects of Mirtoselect®, Virtiva®, and Enovita® on Cognitive Performance and Mood States
This is a randomized, double-blind, placebo-controlled, 4-week intervention clinical study assessing the efficacy of Mirtoselect®, Virtiva® Plus, and Enovita® on cognitive performance and mood states, and the occurrence of…
- Conditions
- Mental Processes, Cognitive Change, Mood Change
- Trial name
- NCT06309914
- Testing
- Enovita Grape Seed Extract, Mirtoselect Bilberry Extract, Virtiva Plus Ginko Biloba Extract
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Depression, Mood Disorders
Cold and Heat Investigation to Lower Levels of Depression
This study will recruit 112 medically healthy adults (aged 18-65) currently experiencing depressive symptoms to be randomized to receive either a single Whole Body Hyperthermia (heat therapy) treatment or a Whole Body…
- Conditions
- Depression, Mood Disorders, Healthy (Controls)
- Trial name
- CHILL'D (NCT06263738)
- Testing
- Whole Body Hyperthermia, Cold Water Plunge
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Barry Sandler
Sleep Quality
Sleep Quality and the Menstrual Cycle
This study aims to examine how ovarian hormone fluctuations across the menstrual cycle affect sleep patterns. Using objective sleep tracking, hormone phase assessment, and validated questionnaires, it will assess changes in sleep…
- Trial name
- NCT06906133
- Testing
- Urinary-hCG
- Where
- 2 sites in Iceland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Akureyri
Major Depressive Disorder (MDD)
Investigating Functional Changes in the Frontotemporal Cortex of Patients With Major Depressive Disorder Following Electroconvulsive Therapy or Magnetic Seizure Therapy Using Functional Near-infrared Spectroscopy (fNIRS)
Against the clinical backdrop of the growing global burden of neuropsychiatric disorders, the rapid rise in depression prevalence, and the frequent association of these conditions with cognitive impairment, this study highlights…
- Trial name
- NCT07533773
- Testing
- Electroconvulsive Therapy, Magnetic Seizure Therapy
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Anhui Medical University
Major Depressive Disorder
Epigenetic Regulation of BDNF in Major Depression
The investigators will (1) detect the associations between brain-derived neurotrophic factor (BDNF) DNA methylation, histone modification, depressive symptoms, suicidal behavior and antidepressant responses in major depressive…
- Trial name
- NCT01182103
- Where
- Taiwan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Glaucoma
Altered Non-Visual Photoreception in Patients With Glaucoma: Impacts on Sleep, Alertness, Mood, and Cognition
The goal of this study is to understand how light sensitivity in the eye affects sleep, mood, alertness, and cognition in adults with glaucoma compared to healthy individuals aged 45-75 years.
- Trial name
- EyeQ (NCT07364929)
- Testing
- Full-spectrum light exposure, Standard indoor light exposure (Control)
- Where
- 2 sites in Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National University of Singapore