Clinical trials: Mood Disorders
Affective Disorder
Towards Neurobiology-based Diagnosis and Treatment of Affective Disorders
The project is a multi-center, prospective cohort study. The study's total targeted enrollment is 400 first-episode patients with major depressive disorder (MDD) and 400 healthy controls.
- Trial name
- NCT03294525
- Testing
- Escitalopram Pill, Duloxetine, Mirtazapine Pill
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Peking University
Cardiovascular Diseases, Mood Disorders
Evaluating the Effects of Omega-3 Fatty Acids on Heart Disease and Behavior
Omega-3 fatty acids are a certain kind of fish fat that has recently been shown to have health benefits. This study will examine the effectiveness of fish oil supplementation for reducing the early signs of heart disease risk and…
- Conditions
- Cardiovascular Diseases, Mood Disorders, Inflammation
- Trial name
- NCT00663871
- Testing
- Fish Oil
- Where
- United States
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Memory Dysfunction, Mood Disorders
To Access the Effect of Brain Pill™ on Working Memory Capacity and Mood Behaviour.
Brain Pill™ is a mental health enhancing and successfully marketed dietary supplement.
- Trial name
- NCT03198936
- Testing
- Cognizin® SynapsaTM
- Where
- India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Sleep, Circadian Dysregulation
The Impact of Artificial Sunlight on Human Sleep and Circadian Rhythms
The purpose of this study is to examine, in healthy controls, whether LED lighting that has a color spectrum similar to that of sunlight is able to differentially impact mood, circadian rhythms, sleep, and behavior, as compared…
- Conditions
- Sleep, Circadian Dysregulation, Mood
- Trial name
- NCT03636360
- Testing
- Light
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Mood Disorders, Healthy
Cholinergic Modulation of Condition and Emotion in Mood Disorders: Functional Neuroimaging Studies
This study looks at the role of a specific brain chemical system in the mood and attention symptoms seen in major depression and bipolar disorders using functional brain imaging.
- Conditions
- Mood Disorders, Healthy, Unipolar Depression, Bipolar Depression
- Trial name
- NCT00055575
- Testing
- Scopolamine Nasal Spray
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Depression, Depression, Postpartum
Chronobiology, Sleep Related Risk Factors and Light Therapy in Perinatal Depression: the Life-ON Project
In a 3 years longitudinal, observational, multicentre study, about 500 women will be recruited and followed-up from early pregnancy (10-15 gestational week) until 12 months after delivery.
- Conditions
- Depression, Depression, Postpartum, Depressive Disorder, Depressive Disorder, Major
- Trial name
- NCT02664467
- Testing
- Philips EnergyUp EnergyLight HF3419/01
- Where
- Switzerland
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Ospedale Regionale di Lugano
PCOS, Depression
Metformin, Vitamin D, and Depression in Polycystic Ovary Syndrome (PCOS) Trial
Open-label randomized clinical trial assessing the efficacy of Metformin versus Vitamin D in improving symptoms of depressed mood in polycystic ovary syndrome.
- Conditions
- PCOS, Depression, Vitamin D Deficiency, Insulin Resistance
- Trial name
- MINDD (NCT03380091)
- Testing
- Metformin, Vitamin D
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Stress, Anxiety
Presence of Aquarium in the Waiting Room of a Geriatric Dental Clinic
The participants in this study will be subjected to a specific clinic waiting area ambience (1- no aquarium, 2- presence of aquarium with no fish, and 3- aquarium with fish) for their period of waiting before their intended…
- Conditions
- Stress, Anxiety, Mood
- Trial name
- NCT04630600
- Testing
- No intervention, Partially-equipped aquarium in the waiting area, Fully-equipped aquarium in the waiting area
- Where
- Switzerland
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Depression
Emotional and Cognitive Control in Late-Onset Depression
This study may help identify how abnormalities in brain systems that control the ability to ignore irrelevant information may contribute to the development of depression in older adults.
- Trial name
- NCT01728194
- Testing
- Escitalopram, Magnetic Resonance Imaging
- Where
- 2 sites in United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Questionnaire Designs, COVID-19 Pandemic
Psychological Effects of the COVID-19 Pandemic on the Hungarian Adult Population
The aim of the study is to explore the psychological effects of the COVID-19 pandemic among Hungarian adults with the use of an anonymous online questionnaire that consists of 65 items.
- Conditions
- Questionnaire Designs, COVID-19 Pandemic, Psychological Stress, Coping Skills
- Trial name
- NCT04426266
- Where
- Hungary
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- Szeged University
Major Depressive Disorder
Prevalence of Major Depression Among Immigrants in Santiago, Chile
The general aim of this study is to explore the prevalence of major depressive disorder and the use of mental health services in the immigrant populations in the Metropolitan Region of Santiago, Chile. The hypotheses are: 1.
- Trial name
- STRING (NCT04114565)
- Where
- Chile
- Volunteers
- 1,092 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Depression, Anxiety
Pharmacogenomic Testing to Optimize Antidepressant Drug Therapy
A randomized controlled trial comparing pharmacogenomic guided versus standard pharmacist care to optimize antidepressant drug therapy.
- Conditions
- Depression, Anxiety, Major Depressive Disorder, Generalized Anxiety Disorder
- Trial name
- NCT03591224
- Testing
- Pharmacogenomic Testing, Pharmacist Standard of Care
- Where
- 2 sites in Canada
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- John Papastergiou Pharmacy Ltd
Stress, Anxiety
Tools for Wellbeing COVID-19 National Study of Undergraduate Students
The study evaluates the effectiveness of yoga practices on reducing stress, negative emotion, anxiety, and depression and on increasing positive emotion, wellbeing and resilience. The study uses randomized wait-list control.
- Conditions
- Stress, Anxiety, Depression, Resilience
- Trial name
- NCT04414371
- Testing
- Yoga
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Polymorphisms, Exercise
The Influence of 5-HTTLPR and BDNF Polymorphisms on Anxiety and Mood After Acute Exercise
The Influence of 5-HTTLPR and BDNF Polymorphisms on Anxiety and Mood After Acute Exercise. Introduction: The 5-HTTLPR (SLC6A4) and BDNF (Val66Met) polymorphism presents an action on the modulation of human behavior and has…
- Conditions
- Polymorphisms, Exercise, Mood
- Trial name
- NCT03556176
- Testing
- Exercise, Quiet rest
- Where
- Brazil
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Anxiety, Stress
The Kiss of Kindness Study II
The objective of this study is to assess the impact of engaging in deliberate acts of kindness on resilience (primary outcome); social interaction anxiety and affect (secondary outcomes); and mood (exploratory outcome) of…
- Conditions
- Anxiety, Stress, Mood, Affect
- Trial name
- NCT04013451
- Testing
- Acts of kindness
- Where
- Canada
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Mood Disorders, Depression
Promoting Widowed Elders Lifestyle After Loss
This study is for adults 60 years and older who are grieving the recent loss of a spouse or partner. Bereavement is one of the most distressing transitions faced by older adults and triggers dramatic changes to older adults'…
- Conditions
- Mood Disorders, Depression, Anxiety, Grief
- Trial name
- NCT02631291
- Testing
- Behavioral self-monitoring, Behavioral self-monitoring + Motivational interviewing
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Anxiety, Mood Disorder
Effectiveness of Using the Progressive Goal Attainment Program in Anxiety and Mood Disorders
The purpose of the present study is to determine the effectiveness and feasibility of the Progressive Goal Attainment Program (PGAP) with individuals with anxiety and mood disorders.
- Trial name
- PGAP (NCT02819986)
- Testing
- Progressive Goal Attainment Program
- Where
- Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
Mood
Chronic Effects of Euphytose® on Psychological and Physiological Measures of Stress
The aim of this study is to assess the chronic effects (14 days) of Euphytose® on psychological state, physiological stress responses and any resulting changes in gut microflora communities as compared to placebo.
- Trial name
- NCT03909906
- Testing
- Euphytose®
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Depression, Bipolar Disorder
Mitochondrial Dysfunction, Inflammation, and White Matter Integrity in Youth With Mood Disorders
This study consists of three separate appointments including a clinical assessment (interview and questionnaires), a blood draw, a social stress test, and a brain MRI.
- Conditions
- Depression, Bipolar Disorder, Bipolar Disorder Not Otherwise Specified, Unspecified Mood Disorder
- Trial name
- NCT02596698
- Where
- 2 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Depression, Anxiety
Technology Enabled Mental Health Intervention for Individuals in the Criminal Justice System
In the United States, over 60% of the 2.2 million people who are incarcerated struggle with mental health problems. Currently, correctional facilities are limited in their ability to provide care.
- Conditions
- Depression, Anxiety, Mood
- Trial name
- NCT03105973
- Testing
- Technology-Enabled CBT Treatment
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jail Education Solutions, Inc.