Clinical trials: Mood Disturbance
Mental Health Mood Disturbance Occupational Stress
Monthly Mood Improvement After Workplace Mindfulness
This randomized controlled pilot trial investigates the effects of a brief workplace mindfulness-based intervention (MBI) on mood among full-time employees in Japan.
- Trial name
- MBI-WORK (NCT07029022)
- Testing
- Mindfulness-Based Intervention (MBI)
- Where
- Japan
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Shinyu Kise
Post-traumatic Stress Disorder, Dissociation
An Intervention to Enhance Well-Being in Trauma Exposed New Mothers
This pilot randomized controlled trial will evaluate the feasibility and effectiveness of a mobile neurofeedback intervention for increasing maternal overall well-being, and measuring whether mothers experience any subsequent…
- Conditions
- Post-traumatic Stress Disorder, Dissociation, Maternal Care Patterns, Infant Behavior
- Trial name
- NCT05474534
- Testing
- Neurofeedback (MUSE 2)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wayne State University
Well-Being, Psychological, Mood Disturbance
Neurofeedback and Well-Being Among People With Co-Occurring Obsessive Compulsive Disorder and Post-traumatic Stress Symptoms
The proposed study will collect novel data evaluating the feasibility of a neurofeedback training program delivered to prospective clients with a history of clinically concerning trauma-related mental health symptoms who are on a…
- Conditions
- Well-Being, Psychological, Mood Disturbance, Emotional Regulation, Dissociation
- Trial name
- NCT07217925
- Testing
- Neuroptimal (Zengar, Inc.) Neurofeedback
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wayne State University
Mood
Novel Objective Digital Biomarkers for Assessing Sub-clinical Mood Disturbances in the Singaporean Population
The investigators aim to assess the relationship between objectives markers (of physiological reactivity) recorded using a smartwatch and self-reported subjective outcomes measured using standardized and non-standardized…
- Trial name
- NCT06115590
- Testing
- Nutritional supplement
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Sleep Disturbance, Mood Disturbance
Enhancement of Sleep Quality and Mood Following Supplementation With Lemon Balm in an Adult Population (Lemslp)
This study aims to investigate the effect of a 4-week dietary intervention of 300mg encapsulated aqueous lemon balm extract on measures of sleep quality, mood and well-being, alongside relevant biomarkers of circadian rhythms in…
- Trial name
- NCT05422599
- Testing
- Lemon balm
- Where
- United Kingdom
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Reading
Self Destructive Behavior, Mood Disturbance
Integration of Augmented Reality in Expressive Art Therapy for Borderline Personality Features
From the last decades, applied approach for the use of augmented reality on clinical and health psychology has grown exponentially.
- Conditions
- Self Destructive Behavior, Mood Disturbance, Self Esteem
- Trial name
- NCT05994105
- Testing
- Art based Augmented Reality
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Bahria University
Depressive Disorder, Sleep Disturbance
iACT & iTBS for Sleep Quality in Depressed Adolescents
This study evaluated whether combining an internet-delivered Acceptance and Commitment Therapy program with intermittent theta burst stimulation improves subjective sleep quality in adolescents with depressive disorders and sleep…
- Trial name
- NCT07807072
- Testing
- Internet-Delivered Acceptance and Commitment Therapy, Intermittent Theta Burst Stimulation
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Central China Normal University
Breast Cancer
Group Therapy for Primary Breast Cancer
The purpose of this study is to determine whether women with primary breast cancer who were randomly assigned to receive a brief group therapy would show a greater reduction in mood disturbance over time compared to those…
- Trial name
- NCT00220792
- Testing
- Brief supportive-expressive group therapy
- Where
- 10 sites in United States
- Volunteers
- 480 people
- Sponsor
- Stanford University
Adolescent Depression
Adolescent Mood During Puberty and Testosterone
Starting at puberty, female adolescents are nearly three-times more likely to develop internalizing disorders, like depression, while male adolescents are two-times more likely to develop externalizing disorders, like attention…
- Trial name
- AMPT (NCT06072677)
- Testing
- Healthy Minds Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Menopause, Depression
Impact of Hot Flashes on Sleep and Mood Disturbance
We plan to enroll premenopausal women in a trial investigating the impact of hot flashes developed in response to an injection of a gonadotropin-releasing hormone agonist (GnRHa), leuprolide (brand name: Lupron), on sleep…
- Conditions
- Menopause, Depression, Hot Flashes
- Trial name
- NCT01116401
- Testing
- leuprolide
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Anxiety, Depression
Health Benefits of Gardening
The objective of the research is to test the hypothesis that participating in group-based gardening or group-based art activities may alter the mental health and cardiac physiological status of a wellness population of women ages…
- Conditions
- Anxiety, Depression, Healthy, Mood Disturbance
- Trial name
- NCT03266120
- Testing
- Art, Gardening
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Florida
Restless Legs Syndrome, Depression
Phase IV Trial With Pramipexole to Evaluate Safety and Efficacy in Patients With RLS Associated With Mood Disturbances
The primary objective of this study is to determine the efficacy of pramipexole 0.125 mg to 0.75 mg daily versus placebo on RLS symptoms and on associated mood disturbances and depressive symptoms, after 12 weeks of treatment
- Trial name
- NCT00356096
- Testing
- pramipexole
- Where
- 54 sites in Finland, France and 7 more
- Volunteers
- 404 people
- Sponsor
- Boehringer Ingelheim
Depressive Disorder, Hormone Disturbance
Effects of the Addition of Metyrapone to Antidepressant Therapy in Depression With Dexamethasone Suppression Test Non-suppression.
The hypothesis of a link between depression and Hypothalamic-Pituitary Axis (HPA) dysfunction is now experienced. Since a first description in 1949 this link has made the HPA one of the most investigated hormonal axis in…
- Trial name
- NCT03491696
- Testing
- Metyrapone
- Where
- 2 sites in France
- Volunteers
- 14 people
- Sponsor
- Centre Hospitalier Rouffach
Depression, Late Life Mood Disorder
A Study on Better Cognitive Functioning Through Braintraining on the Internet
This study evaluates the efficacy of an eight-week online cognitive training program on feasability and on objective and subjective cognitive functions in patients with late life mood disorders (LLMD).
- Conditions
- Depression, Late Life Mood Disorder, Impaired Cognition, Alteration in Mood
- Trial name
- BrainFit (NCT04006756)
- Testing
- Online cognitive training 1, Online cognitive training 2
- Where
- Netherlands
- Volunteers
- 38 people
- Sponsor
- Amsterdam UMC, location VUmc
Nicotine Dependence, Smoking
The Effect of Exercise on Acute Nicotine Withdrawal
The primary aim of this project is to test the effect of exercise on acute nicotine withdrawal. Acute nicotine withdrawal is characterized by a complex array of symptoms associated with increased risk of relapse among individuals…
- Conditions
- Nicotine Dependence, Smoking, Sleep Disorders, Intrinsic
- Trial name
- NicEx (NCT01047930)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Bipolar Disorder, Insomnia
Mindfulness Therapy on Disrupted Sleep in Bipolar Disorder
The investigators propose to investigate the efficacy of a brief (4-session) Body Scan (BS) meditation intervention for individuals with bipolar I disorder with insomnia (i.e. difficulties falling or staying asleep).
- Conditions
- Bipolar Disorder, Insomnia, Hypersomnia, Sleep Problems
- Trial name
- NCT01764035
- Testing
- Body Scan (BS) Meditation Intervention, Brief Supportive Psychotherapy (SP)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Massachusetts General Hospital
Depression, Anhedonia
Family Promoting Positive Emotions Pilot Study
Anhedonia is characterized by loss of interest or pleasure. The proposed pilot study would be the first to test an innovative, neuroscience-informed intervention in mothers reporting depressive symptoms and stress to enhance…
- Conditions
- Depression, Anhedonia, Stress, Depressive Disorder
- Trial name
- NCT05223842
- Testing
- Family Promoting Positive Emotions (F-PPE), Written Information
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Vanderbilt University
Physical Therapy, Resistance Exercise
Resistance Exercise and Sleep Quality by Chronotype
This study examines whether doing moderate resistance exercises in the morning can improve sleep quality and well-being in young adults.
- Conditions
- Physical Therapy, Resistance Exercise, Sleep Disturbances, Sleep Quality
- Trial name
- TRE-SLEEP (NCT07234812)
- Testing
- Moderate-Intensity Resistance Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Medipol University
Sleep Disturbances in Perimenopause
A Study Comparing the Effects of Two Types of Natural Oils Used in a Bedtime Foot Massage Routine on Sleep and Emotional Well-Being in Perimenopausal Women.
This study is being done to find out whether a nightly 5-minute foot massage (Padabhyanga) using Brahmi-Gotukola oil can help women ages 40 to 55 sleep better and feel calmer during perimenopause.
- Trial name
- BG-SLEEP (NCT07274371)
- Testing
- Brahmi-Gotukola oil padabhyanga, Sesame oil Padabhyanga
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Saipriya Gowrishankar
Menopause, Menopausal Symptoms
A Clinical Trial to Evaluate the Effects of A Supplement on Symptoms of Menopause and Overall Well-being
This study evaluates the effects of Primal Harvest's Primal Meno+ supplement on symptoms of menopause and overall well-being in females aged 40-60 who are currently menopausal and experiencing at least two menopausal symptoms.
- Conditions
- Menopause, Menopausal Symptoms, Hot Flashes, Night Sweats
- Trial name
- NCT07903480
- Testing
- Primal Meno+ Supplement
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Primal Harvest, LLC