Clinical trials: Morality
Malaria,Falciparum, Morality
An Observational Study to Assess Effectiveness and Safety of The R21/Matrix-M Malaria Vaccine
This is an observational case-control study to assess the effectiveness of the R21/Matrix-M vaccine against severe malaria, clinical malaria (in high transmission perennial areas), and to assess if the R21 vaccine recipients are…
- Trial name
- NCT07009847
- Testing
- Case control study of clinical malaria, Case control study of severe malaria, Case control study of death (all cause)
- Where
- 5 sites in Burkina Faso, Côte d’Ivoire and 2 more
- Volunteers
- 2,308 people, healthy volunteers welcome
- Sponsor
- Serum Institute of India Pvt. Ltd.
Physical Restraint, Gender Bias
Long-term Outcomes in Older Patients With Physical Restraint
The worldwide population is ageing. Biological sex is first and foremost a genetic modifier of disease. To prevent self-arm many techniques can be used in older patients.
- Conditions
- Physical Restraint, Gender Bias, Morality
- Trial name
- NCT06491706
- Testing
- the was no intervention
- Where
- France
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Beaujon Hospital
Resistance Bacterial, Morality
Azithromycin for Child Survival in Niger: Programmatic Trial (AVENIR)
The MORDOR trial found that biannual distribution of azithromycin to children 1-59 months old reduced child mortality. The World Health Organization (WHO) released conditional guidelines for this intervention, which include…
- Conditions
- Resistance Bacterial, Morality, Child Health, Implementation
- Trial name
- AVENIR (NCT05288023)
- Testing
- Azithromycin for Oral Suspension
- Where
- United States
- Volunteers
- 169,707 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Morality, Diabetes
Saturated Fatty Acids Intake and Mortality, Diabetes, Hypertension and Overweight
The role of saturated fatty acids (SFAs) intake in the development of total death, cardiovascular diseases, diabetes, hypertension and overweight are in great controversy but evidence from large population in China is scant.The…
- Conditions
- Morality, Diabetes, Hypertension, Overweight
- Trial name
- NCT03281512
- Volunteers
- 14,383 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Postoperative Complications, Morality
Postoperative Complications and Mortality With In-Hospital COVID-19 Omicron Infection After Surgery
Postoperative complications and mortality in patients with COVID-19 Omicron infection who have undergone specialized thoracic surgery are scarce.
- Trial name
- NCT06040606
- Testing
- In-Hospital COVID-19 Omicron Infection after surgery
- Where
- China
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Nasopharyngeal Cancer, Screening
Cluster Randomized Controlled Screening Trial for NPC
This study is aimed to estimate the effectiveness of an Epstein-Barr virus (EBV) serology-based screening program to reduce nasopharyngeal carcinoma (NPC) mortality in a cluster randomized controlled trial in an NPC high-risk…
- Conditions
- Nasopharyngeal Cancer, Screening, Morality
- Trial name
- CRCSTNPC (NCT00941538)
- Testing
- Experimental: Screening with EBV VCA/EBNA1-IgA testing
- Where
- 2 sites in China
- Volunteers
- 87,600 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Trauma, Shock, Traumatic
Discriminant Ability of the Shock Index, Modified Shock Index, and Reverse Shock Index Multiplied by the Glasgow Coma Scale on Mortality in Adult Trauma Patients: A PATOS Study
We evaluated a cohort of adult trauma patients transported to emergency departments. The first vital signs were used to calculate the SI, MSI, and rSIG.
- Conditions
- Trauma, Shock, Traumatic, Morality
- Trial name
- NCT05549986
- Testing
- Observational
- Volunteers
- 105,641 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Morality, Remodeling, Ventricular
HIIT Effects on Long-term Survival in Heart Failure Patients
The American Heart Association announces that exercise training should be considered for all stable cardiac patients (Class I, Level A). Therefore, exercise is an important issue for cardiac patients.
- Conditions
- Morality, Remodeling, Ventricular, Heart Failure
- Trial name
- NCT05487716
- Testing
- High-intensity interval training (HIIT)
- Where
- Taiwan
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Non-metastatic Colorectal Cancer, Empathy
Role of Empathy in Curative Treatment Outcomes of Non-metastatic Colorectal Cancer.
The aim of project EMPACOL will be to investigate, while taking into consideration the clinical factors known and well described in the literature, among the non-clinical factors, in particular, patient-healthcare personnel (HCP)…
- Conditions
- Non-metastatic Colorectal Cancer, Empathy, Morbidity, Morality
- Trial name
- EMPACOL (NCT05447611)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Clinical Infection, Outcome
Efficacy and Safety of Ethanol Inhalation on COVID-19 Treatment (a Clinical Trial Study)
Cytokine storm is the cause of many deaths in COVID -19. The antiviral in-vitro effects of ethanol with solving the fat layer and destroying the glycoprotein of coronavirus have already been established.
- Conditions
- Clinical Infection, Outcome, Morality
- Trial name
- COVID-19 (NCT05268419)
- Testing
- Ethanol, Water Distilled
- Where
- Iran
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ali Amoushahi
Surgery, Surgery--Complications
Patterns and Outcomes of Neurosurgery in England Over a Five-year Period
Neurosurgical practice has seen many important changes over several decades with advances in treatments and the types of patients treated.
- Conditions
- Surgery, Surgery--Complications, Neurological Morbidity, Neurological Diseases or Conditions
- Trial name
- NCT05097066
- Testing
- Neurosurgical procedure
- Volunteers
- 371,418 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Happiness, Anxiety
Prosocial Behavior Can Safeguard Mental Health and Foster Emotional Well-being During the COVID-19 Pandemic
The COVID-19 pandemic and the accompanying lockdown measures have made mental health a pressing public health concern. Acts that focus on benefiting others-known as prosocial behaviors-offer one promising intervention that is…
- Conditions
- Happiness, Anxiety, Depression, Morality
- Trial name
- NCT04517006
- Testing
- Self-focused acts, Prosocial acts
- Where
- Canada
- Volunteers
- 1,328 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Surgery, Morality
African Surgical OutcomeS-2 (ASOS-2) Trial
An international, multicentre, African cluster randomised trial. Primary objective : To determine whether increased postoperative surveillance in high-risk adult surgical patients reduces overall in-hospital mortality in surgical…
- Trial name
- ASOS-2 (NCT03853824)
- Testing
- Increased postoperative surveillance, Usual postoperative care
- Where
- South Africa
- Volunteers
- 27,507 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Type2 Diabetes, Coronary Artery Disease
Dietary Analyses in the Nurses' Health Study, Nurses' Health Study II, and Health Professionals Follow-Up Study
To determine the relationships of a variety of nutrients, foods, and dietary patterns with the subsequent risk of developing type 2 diabetes, cardiovascular disease, and mortality in US men and women.
- Conditions
- Type2 Diabetes, Coronary Artery Disease, Morality, Stroke
- Trial name
- Diet (NCT03366532)
- Testing
- Dietary assessments
- Volunteers
- 289,900 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)