Clinical trials: Morbidity
Aneurysmal Subarachnoid Hemorrhage
Clazosentan in Aneurysmal Subarachnoid Hemorrhage
The aim of this study is to demonstrate that clazosentan, administered as a continuous intravenous infusion at either 5 mg/h or 15 mg/h until Day 14 post aneurysmal subarachnoid hemorrhage (aSAH), reduces the incidence of…
- Trial name
- CONSCIOUS-3 (NCT00940095)
- Testing
- Clazosentan 5 m/h, Clazosentan 15 mg/h
- Where
- 145 sites in United States, Argentina and 26 more
- Volunteers
- 577 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Secondary Hyperparathyroidism, Disorder Related to Renal Transplantation
Morbidity Related to Secondary Hyperparathyroidism After Renal Transplantation
The purpose of the study is to evaluate the long term vascular morbidity and mortality in kidney transplant recipients based on one year post transplant levels of intact parathyroid hormone.
- Trial name
- SHPT-RT (NCT01741064)
- Volunteers
- 257 people
- Sponsor
- Skane University Hospital
Schizophrenia, Insulin Resistance
Effectiveness of Aripiprazole for Improving Side Effects of Clozapine in the Treatment of People With Schizophrenia
This study will evaluate the effects of combination treatment with aripiprazole and clozapine on insulin resistance, blood fat levels, and weight gain in people diagnosed with schizophrenia.
- Trial name
- NCT00345033
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Massachusetts General Hospital
Helicobacter Pylori Resistance
Helicobacter Pylori Resistance
The main goal of the study was to characterize the morbidity, immunological, microbiolical and clinical phenotypes of patients with treated- resistance to Helicobacter pylori (HP) infection, and the effect of triple therapy…
- Trial name
- CRIHEP (NCT05019586)
- Testing
- levofloxacin, amoxicillin, clarithromycin
- Volunteers
- 185 people
- Sponsor
- University Hospital of North Norway
Hemorrhage, Cerebrovascular Accident
Antiplatelet Therapy Continuation in Spine Surgery - Its Effect on Postoperative Morbidity and Mortality
The objective of this study is to evaluate the safety of antiplatelet (APA)therapy continuation in patients undergoing lumbar spine surgery (laminectomy, discectomy and foraminotomy), and to gather evidence-based data regarding…
- Conditions
- Hemorrhage, Cerebrovascular Accident, Myocardial Infarction, Pulmonary Embolism
- Trial name
- NCT01006083
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Respiratory Tract Infections
Study of the Effect of Probiotics on Respiratory Morbidity After Influenza Vaccination of Elderly in Nursing Homes
The purpose of this study is to determine whether probiotic treatment improves the protection against respiratory infections after influenza vaccination in elderly living in nursing homes.
- Trial name
- NCT00849277
- Testing
- Lactobacillus casei Shirota
- Where
- Belgium
- Volunteers
- 737 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Disc Disease
Epidural Steroid Following Discectomy for Herniated Disc Reduces Morbidity
Focus of this study is evaluation of the outcome, neurologic impairment and safety of epidural steroide following lumbar discectomy for herniated disc disease.
- Trial name
- NCT01499641
- Testing
- Methylprednisolone
- Where
- 3 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Lung Transplantation
Impact of the Age Difference Between the Donor and Recipient on the Morbidity and Mortality After Lung Transplantation. Study on a National Multicenter Cohort (COLT)
It is commonly accepted that the characteristics of the organ donor impact on the future post transplant. In lung transplantation (LP), the defining characteristics of the "ideal" donor includes an age less than 55 years.
- Trial name
- NCT02855372
- Testing
- Lung transplantation
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Pharmacological Action, Post Operative Pain
The Postoperative Lidocaine and Ketamine Effects on Morphine Requirement in Bariatric Surgery
The goal of this observational study is to evaluate the quality of postoperative analgesia in a group of obese patients schedule to bariatric surgery under TIVA Opiod-free after to receive lidocaine and ketamine perfusion.
- Conditions
- Pharmacological Action, Post Operative Pain, Opioid Use, Obesity, Morbid
- Trial name
- NCT05591105
- Testing
- Control Group
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Tiva Group
Atrial Arrhythmia
EMERALD - AssEssment of CoMorbidities & Atrial ArRhythmiA Burden in DuaL-Chamber PaceD Patients
The purpose of this study is to evaluate the incidence and evolution over-time of co-morbidities in a general dual-chamber pacemaker population (n=2188 patients) through a 2 years follow-up.
- Trial name
- EMERALD (NCT01188356)
- Where
- 190 sites in United States, Australia and 10 more
- Volunteers
- 4,350 people
- Sponsor
- MicroPort CRM
Obesity, Morbid, Stem Cells
Effect of Weight Loss Surgery on Stem Cells.
Obesity and diabetes are linked to increased risk for health problems such as heart attack, stroke, and death. At the cellular level, obesity and diabetes increase levels of harmful inflammatory cells (M1 macrophages) and…
- Conditions
- Obesity, Morbid, Stem Cells, Cardiovascular Morbidity
- Trial name
- NCT04132531
- Testing
- Bariatric (weight loss) surgery
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Digestive
Determinants of Digestive Morbidity in Neonatal Jaundice
Objective To explore the factors associated with adverse digestive system outcomes in neonates with jaundice. Methods A retrospective analysis was conducted on clinical data of hospitalized neonates admitted to the Department of…
- Trial name
- NCT07475624
- Testing
- Observation (Retrospective Cohort Study)
- Where
- China
- Volunteers
- 3,218 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Jilin University
Cirrhosis
Allopurinol to Prevent Cirrhosis Related Morbidities
The study aims to compare the potential benefit of allopurinol in reducing the risk of developing cirrhosis-related complications, delaying the onset of hepatocellular carcinoma, and improving survival.
- Trial name
- NCT05545670
- Testing
- Allopurinol 300 MG
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Maternal Morbidity, Antenatal Health
Partnering With Antenatal Navigators to Transform Health in Pregnancy
The Partnering with Antenatal Navigators to Transform Health in Pregnancy (PATH) study aims to evaluate whether an antenatal patient navigation program improves maternal health, neonatal health, pregnant women's experiences, and…
- Conditions
- Maternal Morbidity, Antenatal Health, Neonatal Morbidity, Retention in Care
- Trial name
- PATH (NCT06941974)
- Testing
- Patient Navigation Program
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Northwestern University
Cardiovascular Diseases, Mental Disorder
A Phone-call With a Student/General Practitioner Team to Impact Morbidity of Chronic Patients During COVID-19 Containment
Following the announcement of the containment of the population due to the COVID-19 epidemic on March 17, 2020 in France, a notable decrease in the number of consultations in general practice was reported.
- Trial name
- COVIQuest (NCT04359875)
- Testing
- Phone-call screening and management by a medical student/general practitioner tandem
- Where
- France
- Volunteers
- 22,000 people
- Sponsor
- University Hospital, Tours
Respiratory Distress Syndrome
Cord Blood 25(oh)-Vitamin D Level in Preterm Infants and Associated Morbidities
Experimental and observational studies have shown that vitamin D deficiency may be associated with an increased risk for non-bone diseases and/or abnormal development for the other systems of fetus.
- Trial name
- NCT01812681
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Dr. Sami Ulus Children's Hospital
Biliary Strictur After Hepatojejunostomy (HJ), Morbidity and Mortality After and Around HJ
Long Time Follow up After HJ Following Iatrogenic Bile Duct Injuries
Introduction: Bile duct injury (BDI) after cholecystectomy remains a serious complication with major implications for patient outcome. For most major BDIs, the recommended method of repair is a hepaticojejunostomy (HJ).
- Trial name
- NCT01447030
- Volunteers
- 139 people
- Sponsor
- Odense University Hospital
Chest Injury Trauma Blunt
Chest Trauma Scoring Systems as Predictors of Morbidity and Mortality in Iraq
This prospective observational study aims to evaluate the effectiveness of chest trauma scoring systems in predicting morbidity and mortality in patients with blunt chest trauma in Iraq.
- Trial name
- CTS (NCT06737575)
- Where
- Iraq
- Volunteers
- 190 people
- Sponsor
- Al-Nahrain University
Stomach Neoplasms, Gastric Cancer
Specialization in Gastric Cancer Surgery
Specialization is having competent and effective knowledge on a subject, and the tendency towards specialization is increasing due to the fact that it increases the success in the follow-up and treatment process of diseases.
- Trial name
- NCT05280665
- Testing
- Specialization
- Where
- Turkey (Türkiye)
- Volunteers
- 537 people
- Sponsor
- Karadeniz Technical University
Airway Morbidity
Comparison of Reduced Cuff-pressure of the Laryngeal Tube Under General Anesthesia
Optimization the cuff pressure of the laryngeal tube (LT) in relation of the mechanical ventilation, and the reduction of potential leakage mucosal trauma.
- Trial name
- LTS (NCT02300337)
- Testing
- Reduce Cuff pressure
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Johannes Gutenberg University Mainz