Clinical trials: Morbidly Obese Patients
Morbid Obesity
The Effects of Exenatide After Gastric Restriction
The purpose of this study is to describe change in body weight in non-diabetic morbidly obese patients after laparoscopic adjustable gastric banding (LAGB) with twice daily exenatide or placebo injections.
- Trial name
- AGREE (NCT00872378)
- Testing
- Exenatide
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Advanced Specialty Care
Obesity
Does Bariatric Surgery Changes Eating Habits and Addiction in Morbid Obesity?
1. Obesity is a big health problem worldwide. 2. Mostly obese people have food addiction and bad eating habits. 3. Bariatric surgery is a good alternative for patients who failed to loose weight with other measures like…
- Trial name
- NCT01412268
- Volunteers
- 35 people
- Sponsor
- Bezmialem Vakif University
Desaturation of Blood, Colonoscopy
The Use of High Flow Nasal Cannula, Standard Face Mask and Standard Nasal Cannula in Morbidly Obese Patients
It is standard practice in the United States and many parts of world to perform Gastrointestinal endoscopy with the patient under deep intravenous sedation.
- Trial name
- NCT03479905
- Testing
- Salter nasal cannula, Face mask, High Flow Nasal Cannula
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- University of Texas Southwestern Medical Center
Obesity
The Influence of Induction Anesthetic Agents on Serum Cortisol Concentration in Morbidly Obese Patients.
The effect of etomidate administration on the adrenal cortex in obese patients is still unclear. The objective of the study was to determine the influence of single dose of etomidate on cortisol secretion in morbidly obese.
- Trial name
- NCT01930019
- Testing
- Intravenous administration of the induction agent of general anesthesia (etomidate or thiopental)
- Where
- Poland
- Volunteers
- 82 people
- Sponsor
- Military Institute od Medicine National Research Institute
Morbid Obesity, Anorectal Diseases
GLP-1 Receptor Agonists and Early Proctologic Effects in Morbid Obesity
Prospective observational cohort study evaluating the early proctologic effects of GLP-1 receptor agonist therapy in morbidly obese patients.
- Conditions
- Morbid Obesity, Anorectal Diseases, Drug-Related Side Effects and Adverse Reactions, Constipation
- Trial name
- GLP-PROCT (NCT07668765)
- Testing
- GLP-1 receptor agonist therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Gazi University
Bariatric Surgery Candidate, Obesity, Morbid
Korean OBEsity Surgical Treatment Study
This trial is a multi-center, single-arm, prospective, observational cohort study of patients undergoing primary bariatric surgical procedures in Korea.
- Trial name
- KOBESS (NCT03100292)
- Testing
- Sleeve gastrectomy or Roux-en-Y gastric bypass
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Bundang Hospital
Obesity
Impact of Laparoscopic Gastric Bypass Surgery and Weight Reduction on Lower Esophageal Sphincter (LES)
The purpose with this study is to investigate whether gastric bypass surgery and the following weight reduction impact the tone in esophageal sphincters and the esophageal function.
- Trial name
- NCT01672034
- Testing
- Laparoscopic gastric bypass surgery
- Where
- Sweden
- Sponsor
- Örebro University, Sweden
Morbid Obesity D009765
Preoperative Omega-3 Polyunsaturated Fatty Acids in Morbidly Obese to Reduce Liver Volume and Steatosis
Hepatomegaly is common in the morbidly obese patients and it may hamper the access to the hiatal region during bariatric surgery.
- Trial name
- Omegobese (NCT03006016)
- Testing
- Omega-3 Fatty Acid
- Where
- 2 sites in France
- Volunteers
- 44 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Obesity, Obesity, Morbid
Behaviour of Intravenous Solutions in Obese Patients Under General Anesthesia
There is no objective evidence of how long intravenous solutions remain inside venous blood vessels after they have been administered, therefore there is no definite guideline of how to administer them in the preoperative…
- Trial name
- NCT01652131
- Testing
- Tetrastarch (130/0.4)
- Where
- Mexico
- Volunteers
- 12 people
- Sponsor
- National Institute of Medical Sciences and Nutrition, Salvador Zubiran
Bariatric Surgery Candidate
Laryngeal Mask Airway as a Bridge for Intubation of Obese Patients for Sleeve Gastrectomy
Ventilation, as well as intubation of a morbidly obese patient, is challenging and require special preparations and skilful hands, in this study laryngeal mask airway insertion is used as a bridge for intubation to facilitate…
- Trial name
- NCT04378192
- Testing
- Laryngeal mask airway, face mask
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Suez Canal University
Obesity, Morbid
Pharmacokinetics of Propofol in Morbidly Obese Patients
The objectives of this study are To determine PK of propofol in bariatric patients To identify the physiological variables that induce propofol PK changes in bariatric patients, when compared to a normal-weight population.
- Trial name
- NCT01536002
- Testing
- Propofol
- Where
- Norway
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Anomaly; Venous Return
Volume-challenge in Morbid Obesity
Preoperative venous return stability and euvolemia is essential in management of morbidly obese patients. Fluid therapy regimes for patients with high BMI, especially with focus on preoperative management, are rare and not in…
- Trial name
- NCT01748513
- Testing
- preoperative venous return optimizing
- Where
- Sweden
- Volunteers
- 34 people
- Sponsor
- Umeå University
Intubation;Difficult, Morbid Obesity
Comparison of Intubation Success Rates of 3 Different Laryngoscope Blade Types in Morbidly Obese Patients
Reusable laryngoscope blades, which are the most commonly used devices for airway management, have been reported to be frequently contaminated and a possible source of infection.
- Trial name
- NCT04477148
- Testing
- endotracheal intubation
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Turkish Society of Anesthesiology and Reanimation
Restrictive Lung Disease
Effects of Dexmedetomidine on Oxygenation and Lung Mechanics in Morbidly Obese Patients Undergoing Bariatric Operations
The study aims to investigate the effect of dexmedetomidine on oxygenation and lung mechanics in morbidly obese patients
- Trial name
- NCT02843698
- Testing
- Dexmedetomidine, Normal saline
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Morbid Obesity
Interaction Between Head/Neck Position and C-MAC Blade Geometry on Videolaryngoscopic Intubation in Morbidly Obese Patients: A Randomized Controlled Trial
This study aims to explore the effect of head/neck position (sniffing vs ramped) and C-MAC blade geometry (MAC vs D-blade) on intubation in morbidly obese patients. The patients will be randomized into 4 groups: 1.
- Trial name
- C-MAC (NCT07636746)
- Testing
- Sniffing position and using MAC blade., Ramped position and MAC Blade, videolaryngoscopy
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Lung Function, Bariatric Surgery
Pre-op Use of Incentive Spirometry in Obese Patients
The purpose of this study is to evaluate the use of preoperative incentive spirometry (IS) as an aid to improve postoperative lung function.
- Trial name
- IS (NCT01004146)
- Testing
- Incentive Spirometry
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
To Evaluate Clinical Results, Insulin Resistance and Inflammatory Response to Trauma in Morbidly Obese Patients
Clinical Evaluation, Organic Response in Obesity Patients Subjected to Vertical Videolaparoscopy Gastroplasty With or Without Perioperative Cares Recommended by the Acerto Project. Randomized Study.
Background To evaluate clinical results, insulin resistance and inflammatory response to trauma in morbidly obese patients undergoing laparoscopic Sleeve gastrectomy who received either traditional preoperative care or treatment…
- Trial name
- NCT02113995
- Testing
- ACERTO protocol vs Traditional care
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Cuiaba University
Obesity, Morbid Catheterization, Peripheral
Radial Artery Dimensions and the Effect of Anaesthetic Induction in Morbid Obesity
This single-centre prospective study measured the internal diameter of the radial artery and the distance between the skin surface and the arterial lumen by ultrasound in 76 adults with a body mass index of 40 kg/m2 or above who…
- Trial name
- NCT07868978
- Testing
- 20 G arterial cannula, 18 G arterial cannula
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Hilal Subaşı Artıran
Obese, Antibiotic Prophylaxis
Serum Concentration of CEFOxitin Used for Antibiotic Prophylaxis in Obese Patients Undergoing BARiatric Surgery
Obesity is a pandemic problem in modern societies. Bariatric surgery (gastric by-pass and sleeve gastrectomy) has emerged as an efficient treatment to reduce morbidity and mortality related to obesity.
- Conditions
- Obese, Antibiotic Prophylaxis, Bariatric Surgery Candidate
- Trial name
- CEFOBAR (NCT03306290)
- Testing
- Serum dosage of antibiotic prophylaxis CEFOXITIN
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Central Hospital, Nancy, France
Morbid Obesity
Sonographic Evaluation of Visceral Fat After Bariatric Surgery
Excess visceral fat is a key factor in the development of metabolic syndrome associated with obesity. After bariatric surgery, patients experience weight loss accompanied by a decrease in the amount of total body fat.
- Trial name
- NCT01285791
- Where
- Israel
- Volunteers
- 39 people
- Sponsor
- Hadassah Medical Organization