Clinical trials: Morning Sickness
Hyperemesis Gravidarum, Emesis
MinSafeStart - Decision Aid Tool for Better Treatment of Nausea and Vomiting During Pregnancy
Nausea and vomiting in pregnancy (NVP) is affecting up to 70% of pregnant women. Studies have also shown that NVP may have a profound impact on pregnant women's wellbeing and that even mild NVP symptoms have been shown to…
- Conditions
- Hyperemesis Gravidarum, Emesis, Emesis Pregnancy
- Trial name
- NCT04719286
- Testing
- MinSafeStart app
- Where
- Norway
- Volunteers
- 217 people
- Sponsor
- Hedvig Marie Egeland Nordeng
Hyperemesis Gravidarum
Pregnancy Specific Nausea Questionnaire (PUQE) Translated and Tested in Norwegian
Nausea in early pregnancy (emesis gravidarum) is very common but most often self-limiting. Hyperemesis gravidarum; where nausea and vomiting is severe and protracted is potentially dangerous for the woman and her foetus and…
- Trial name
- PUQE-N (NCT01836835)
- Testing
- Pregnancy Unique Questionnaire of Emesis (PUQE), 24 hours self-reported nutritional intake form
- Where
- 2 sites in Norway
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Nausea and Vomiting
Prevalence of Hyperemesis Gravidarum
Nausea and vomiting during pregnancy represent one of the most common symptoms of pregnancy, affecting 35 to 91% of women. Most often, the symptoms are mild, without impairment of quality of life and disappear at the end of the…
- Trial name
- PHyperEG1 (NCT06415084)
- Where
- France
- Volunteers
- 619 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Pregnancy
Date Fruit Benefits to Treat Morning Sickness in First Trimester of Pregnancy
The goal of this randomized clinical trial is to evaluate role of date fruit in alleviating morning sickness of pregnancy in pregnant females.
- Trial name
- NCT07354529
- Testing
- Date fruit, Doxylamine succinate 10 mg + Pyridoxine HCl 10 mg, Diet
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Bahria University
Hyperemesis Gravidarum
Use of the Modified PUQE Score on Admitted Cases of Hyperemesis Gravidarum (HG) to Guide Response to Treatment
Use of the PUQE score to judge the need for admission in cases of hyperemesis gravidarum Evaluation of the response to treatment by the PUQE score
- Trial name
- NCT04785911
- Testing
- Antiemetic Combinations
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Tasnem Abo-elouon
Hyperemesis Gravidarum, Pregnancy
Effects Of Emotional Freedom Technique and Hypermesis Gravidarum
The purpose of this clinical study is to determine whether EFT (Emotional Freedom Techniques) is effective in alleviating nausea and vomiting in pregnant women with hyperemesis.
- Trial name
- PREGNANCY (NCT06442813)
- Testing
- EFT GROUP
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Morning Sickness
A Multicenter Trial of the Efficacy and Safety of Diclegis® for Nausea and Vomiting of Pregnancy in Pregnant Adolescents
The primary objective of this study is to compare the efficacy of Diclegis for the treatment of nausea and vomiting of pregnancy (NVP) in pregnant adolescents aged 12 to 17 years with placebo.
- Trial name
- PED-301 (NCT02045901)
- Testing
- Diclegis
- Where
- 8 sites in United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Duchesnay Inc.
Nausea Gravidarum, Hyperemesis Gravidarum
Tablet Ginger Versus Tablet Doxylamine Succinate in Control of Nausea and Vomiting in Pregnancy
Nausea and vomiting are common GI symptoms of pregnancy. Multiple managing options have been used for NVP. Doxylamine succinate is used as first line treatment for NVP despite that alternative modalities such as ginger extracts…
- Trial name
- GDNVP (NCT06772974)
- Testing
- Doxylamine Succinate USP, Ginger
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Nawaz Sharif Medical College
Hyperemesis Gravidarum, Nausea Gravidarum
Chewing Gum Containing Vitamin-c to Treat Emesis Gravidarum
Nausea and vomiting is a common complication of pregnancy and occurs in 70-80% of all pregnancies. The symptoms usually start 2-4 weeks after fertilization and peak between the 9th and 16th week of gestation.
- Conditions
- Hyperemesis Gravidarum, Nausea Gravidarum, Vitamin C Deficiency
- Trial name
- NCT04284696
- Testing
- Pregnan-C-Gum(R) chewing gum
- Where
- Austria
- Volunteers
- 126 people
- Sponsor
- Medical University of Vienna
Hyperemesis Gravidarum
The Effect of Guided Imagery and Diaphragmatic Breathing Exercise in Pregnant Women With Hyperemesis Gravidarum
Objective: The aim of the researchers is to determine the effects of guided imagery and diaphragmatic breathing exercise application on nausea, vomiting severity, and anxiety level in pregnant with hyperemesis gravidarum.
- Trial name
- NCT05829473
- Testing
- Breathing Exercise Group, Guided Imagery Group
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Gaziantep Islam Science and Technology University
Hyperemesis; Gravidarum, With Dehydration
Endothelial Dysfunction in Hyperemesis Gravidarum
The purpose of the study is to determine serum inflammatory adhesion molecules levels in hyperemesis gravidarum
- Trial name
- NCT02989337
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Nausea and Vomiting of Pregnancy
The Efficacy Of Diclectin® For Nausea And Vomiting Of Pregnancy
The purpose of this study is to determine whether Diclectin® (doxylamine succinate USP 10 mg and pyridoxine HCl 10 mg) is more effective at controlling the nausea and vomiting of pregnancy than a placebo.
- Trial name
- NCT00614445
- Testing
- doxylamine succinate 10 mg/pyridoxine hydrochloride 10 mg
- Where
- 7 sites in United States
- Volunteers
- 280 people
- Sponsor
- Duchesnay Inc.
Morning Sickness
The Efficacy and Safety of Bonjesta® for Nausea and Vomiting of Pregnancy in Pregnant Adolescents
The primary objective of this study is to compare the efficacy of Bonjesta for the treatment of nausea and vomiting of pregnancy (NVP) in pregnant adolescents aged 12 to 17 years with placebo.
- Trial name
- NCT05289557
- Testing
- Bonjesta
- Where
- 10 sites in United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Duchesnay Inc.
Pregnancy, Pregnancy Complications
PregSource: Crowdsourcing to Understand Pregnancy
PregSource uses a crowd-sourcing approach, asking pregnant women to enter information regularly and directly about their pregnancies throughout gestation and the early infancy of their babies into online surveys and trackers via…
- Conditions
- Pregnancy, Pregnancy Complications, Morning Sickness, Diabetes, Gestational
- Trial name
- PregSource (NCT02577536)
- Testing
- No Interventions
- Where
- United States
- Volunteers
- 2,359 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hyperemesis Gravidarum, Pregnancy Related
The Levels of the Orexin, Galanin and aMSH and CART in Patients With Hyperemesis Gravidarum
Hyperemesis gravidarum is a disease of unknown etiology that is frequently encountered in pregnant women and seriously impairs their quality of life.
- Trial name
- NCT05446025
- Testing
- Blood sample
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Siirt University
Hyperemesis Gravidarum
Comparison of Gabapentin and Metoclopramide for Treating Hyperemesis Gravidarum
The investigators will compare the effectiveness of gabapentin to metoclopramide for 1 week among 60 women with hyperemesis gravidarum (HG) in this randomized, double-blinded trial.
- Trial name
- NCT02163434
- Testing
- Gabapentin, Metoclopramide
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- State University of New York at Buffalo
Hyperemesis Gravidarum - Severe, Resistin
First Trimester Resistin Levels in HG
This cross-sectional case-control study was conducted in Tuzla State Hospital Obstetrics Clinic in Turkey. The study evaluated 400 pregnant women during their first trimester of pregnancy.
- Conditions
- Hyperemesis Gravidarum - Severe, Resistin, Gestational Diabetes Mellitus (GDM)
- Trial name
- NCT06757374
- Testing
- Resistin
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Cannabis Use Disorder
Haloperidol Versus Ondansetron for Cannabis Hyperemesis Syndrome (HaVOC)
Cannabis Hyperemesis Syndrome (CHS) has become a well-documented syndrome since 2004 and is expected to increase in prevalence with continuing liberalization of marijuana and recognition of the disease.
- Trial name
- HaVOC (NCT03056482)
- Testing
- Ondansetron 8mg, Haloperidol 0.05mg/kg, Haloperidol 0.1mg/kg
- Where
- 3 sites in Canada
- Volunteers
- 33 people
- Sponsor
- Dr. Marco L.A. Sivilotti
Hyperemesis Gravidarum, Nausea Gravidarum
Validating the Effect og Ondansetron and Mirtazapine in Treating Hyperemesis Gravidarum
The aim is to investigate the efficacy of mirtazapine and ondansetron as treatment for hyperemesis gravidarum(HG). The setup is a double-blind multicenter trial where patients suffering from HG will be randomized to treatment…
- Conditions
- Hyperemesis Gravidarum, Nausea Gravidarum, Vomiting of Pregnancy
- Trial name
- VOMIT (NCT03785691)
- Testing
- Mirtazapine, Ondansetron
- Where
- 7 sites in Denmark
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Hyperemesis Gravidarum
The Effect of Mint Flavored Chewing Gum on Hyperemesis Gravidarum Nausea Vomiting Severity, Coping With Stress and Anxiety Level in Pregnants With Hyperemesis Gravidarum
In the research planned as a randomized controlled study, the experimental groups will be administered routine hyperemesis gravidarum (HG) treatment as well as chewing mint-flavored gum, while the control group will only receive…
- Trial name
- NCT06266819
- Testing
- chewing gum
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ordu University