Clinical trials: Mortality
Maternal Morbidity and Mortality
Creating VIP Corps to Reduce Maternal Deaths
The goal of this observational study is to create and rigorously evaluate a violence intervention and prevention corps (VIP Corps) training using a randomized controlled trial among undergraduate and professional students; and to…
- Trial name
- NCT06089109
- Testing
- The Big 3, Implementation and Effectiveness of VIP Corps Training
- Where
- United States
- Volunteers
- 598 people, healthy volunteers welcome
- Sponsor
- Ann Coker
All-cause Mortality, Cardiovascular Disease
The Global Cardiovascular Risk Consortium
The Global Cardiovascular Risk Consortium (GCVRC) brings together harmonized individual-level data from currently more than 2 million (anticipated: approximately 3 million) individuals across 133 cohorts, 40 countries, and 6…
- Trial name
- NCT05466825
- Where
- Germany
- Volunteers
- 3,000,000 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Surgery Complications, Surgery
SurgWeek-2: Identifying the Global Burden of Post Operative Complications: an International Prospective Cohort Study Protocol
This study aims to assess and improve the global outcomes following surgery. Every year approximately 313 million operations are performed, with 50 million people experiencing a complication and unfortunately 3.5 million people…
- Conditions
- Surgery Complications, Surgery, Global Surgery, Robotic
- Trial name
- SurgWeek-2 (NCT07785076)
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
no Spedific Condition, All-cause In-patient Mortality
Nurse Graduateness and Patient Outcomes: a Cross Sectional Pilot Study
This research project is relevant to the identification of the relationship, and its significance, between patient morality and a number of demographic, clinical and corporate characteristics.
- Trial name
- NCT02705001
- Testing
- all admissions except accident and emergency
- Volunteers
- 1,252 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Pre-eclampsia, Hypertension, Pregnancy Induced
Community Level Interventions for Pre-eclampsia
This project is being undertaken to test the hypothesis that implementing a community based package of care for women with hypertensive disorders of pregnancy will result in overall improvement in maternal and neonatal outcomes.
- Trial name
- CLIP (NCT01911494)
- Testing
- Community Engagement, PIERS on the Move mHealth decision aid, Magnesium Sulfate
- Where
- 4 sites in India, Mozambique and 2 more
- Volunteers
- 87,500 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Infant, Newborn, Infant, Small for Gestational Age
Vitamin E for Extremely Preterm Infants
The purpose of this pilot trial is to test the safety and efficacy of administering one dose of vitamin E, via a tube into the stomach, to extremely preterm infants (less than 27 weeks gestation and less than 1000 grams birth…
- Conditions
- Infant, Newborn, Infant, Small for Gestational Age, Infant, Very Low Birth Weight, Infant, Premature
- Trial name
- NCT01193270
- Testing
- Vitamin E
- Where
- 16 sites in United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Stillbirth and Neonatal Mortality, Perinatal Mortality
Perinatal Mortality Outcomes Through Household Infection Pathways
The goal of this trial is to learn if replacing household soil floors with concrete floors can prevent deaths of infants around the time of birth, including stillbirths and deaths in the first month of life in rural Bangladesh.
- Conditions
- Stillbirth and Neonatal Mortality, Perinatal Mortality, Infant Mortality, Child Mortality
- Trial name
- POTH (NCT07620613)
- Testing
- Concrete household floor
- Where
- Bangladesh
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Stanford University
Trauma Injury, Haemorrhagic Shock
Prediction of Massive Transfusion in Trauma Patients
Since the 2000s, many prognostic scores were developed to predict traumatic haemorrhage. Most of these studies were retrospectives based on registers.
- Conditions
- Trauma Injury, Haemorrhagic Shock, Bleeding, Emergencies
- Trial name
- MTP (NCT04561050)
- Testing
- Comparison of score performances (Overall performance, discrimination and calibration)
- Where
- Switzerland
- Volunteers
- 13,222 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Child Mortality
REACH2: Implementation Research on Bi-Annual Mass Distribution of Azithromycin to Children 1-11 Months in Côte d'Ivoire
REACH2 is a three-year implementation research study designed to examine the implementation through a mass drug administration platform of bi-annual single-dose azithromycin to reduce child mortality among children ages 1 to 11…
- Trial name
- REACH (NCT05016895)
- Testing
- Single-dose azithromycin
- Where
- Côte d’Ivoire
- Volunteers
- 767,535 people, healthy volunteers welcome
- Sponsor
- FHI 360
Aging, Sarcopenia
A Prospective Cohort Study of Aged People for Chronic Diseases
This study is a hospital-based, prospective cohort study to elucidate the predictive factors including muscle and fat mass for chronic diseases and mortality in elderly persons aged 60 years and older.
- Trial name
- HAPPY (NCT02640872)
- Where
- South Korea
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Chronic Hepatitis b
Cross Sectional Survey on the Burden and Impacts of Chronic Hepatitis B in the Rural Area of Niakhar, Senegal
This study aims at estimating the prevalence of chronic hepatitis B virus (HBV) infection in rural Senegal (area of Niakhar) and at evaluating the associated burden in terms of both health-related and socio-economic consequences.
- Trial name
- AMBASS (NCT03215732)
- Testing
- HBV testing with dried blood spots (DBS) technique
- Where
- Senegal
- Volunteers
- 3,119 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Corticosteroids, Covid19
Short Term Corticosteroids in SARS-CoV2 Patients
The investigators reviewed the charts of SARS-CoV-2 patients with pneumonia and moderate to severely elevated CRP and worsening hypoxemia who were treated with early, short-term dexamethasone.
- Conditions
- Corticosteroids, Covid19, SARS-CoV 2, Steroids
- Trial name
- NCT04445506
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
HIV, HIV Testing
Home-based Intervention to Test and Start
This study aims to establish the causal impact of two interventions - micro-incentives and a male-sensitive HIV- specific decision support app - on population-level HIV viral load and HIV-related mortality in men, as well as on…
- Conditions
- HIV, HIV Testing, Linkage to Care
- Trial name
- HITS (NCT03757104)
- Testing
- micro-incentive, EPIC-HIV, micro-incentive and EPIC-HIV
- Where
- South Africa
- Volunteers
- 4,667 people, healthy volunteers welcome
- Sponsor
- Africa Health Research Institute
Sepsis, Septic Shock
Influence of Cytosorb on Amount of Catecholamine and Mortality in Sepsis
The aim of this retrospective study was to identify if the enrolled patient might have had a profit of Cytosorb therapy. Primarily the decline in catecholamine therapy under Cytosorb therapy will be investigated.
- Conditions
- Sepsis, Septic Shock, Cytokine Storm, Cytokine Release Syndrome
- Trial name
- NCT04567199
- Testing
- Observational, retrospective
- Where
- Austria
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Surgery--Complications
Predicting Morbidity and Mortality in Elderly Surgical Patients
This proposed multicentre study builds on the findings of our recent validation of USEM and mCriSTAl predictive tools in a single centre at the Complejo Hospitalario de Navarra, whose results were recently published…
- Trial name
- NCT05216107
- Where
- Spain
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Hospital of Navarra
Cardiovascular Diseases, Cardiovascular Morbidity
Prediction of the Risks of Cardiovascular Mortality
Monitoring risks of cardiovascular diseases in working population (18 - 65 years old) by monitoring their BMI, ankle-brachial index with pulse wave velocity, cholesterol and glycemia.
- Conditions
- Cardiovascular Diseases, Cardiovascular Morbidity, Stroke, Embolism
- Trial name
- NCT06103448
- Testing
- Ankle-brachial index - system 100
- Where
- Czechia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Jan Evangelista Purkyne University
Contraception, Contraception Behavior
A Randomized-Controlled Trial to Increase the Uptake of LARCs in Cameroon
Cameroon exhibits a high and non-decreasing level of maternal mortality (roughly 600 per 100,000 live births), partially related to its relatively high total fertility rate (roughly 4.6).
- Conditions
- Contraception, Contraception Behavior, Contraceptive Usage, Contraceptive Method Switching
- Trial name
- HGOPY (NCT03733678)
- Testing
- Price discounts for SARCs, Price discounts for LARCs, Sequential vs. simultaneous recommendations
- Where
- Cameroon
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- World Bank
Gestational Hypertension
Digital Solutions to Reduce Maternal Morbidity and Mortality in Pregnant Refugee Women
The goal of this observational study is to use digital health tracking to improve how high blood pressure and other health issues are detected in pregnant refugee women.
- Trial name
- NCT06647511
- Testing
- Nokia-Withings BPM Connect Blood Pressure Monitor, Smartwatch Devices
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Liver Neoplasms, Sarcopenia
Impact of Sarcopenia on Postoperative Outcomes of Patients Undergoing Liver Resection
The investigators will investigate the impact of different biometric parameters (Body mass index, sarcopenia, lean muscle mass, hand-grip strength, gait speed, fat composition) on the postoperative outcomes of patients undergoing…
- Conditions
- Liver Neoplasms, Sarcopenia, Postoperative Complications
- Trial name
- NCT03630978
- Testing
- Liver resection
- Where
- Italy
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- San Camillo Hospital, Rome
Malnutrition
Non Randomized Controlled Intervention Study Comparing Two Interventions of Nutritional Supplement on Malnutrition, Health and Mortality
The hypothesis for the study is that 12 months of a Ready-To-Use Supplementary Food (RUSF) distributions have a greater impact on children's health than the standard RUSF distributions during the hunger gap period (june to…
- Trial name
- NRCI-ASPE (NCT02085044)
- Testing
- Ready-to-Used Supplement Food administration
- Where
- Chad
- Volunteers
- 5,700 people, healthy volunteers welcome
- Sponsor
- France Broillet