Clinical trials: Mortality After Major Non Cardiac Surgery
Perioperative/Postoperative Complications, Morbidity, Multiple
Machine Learning Modeling of Intraoperative Hemodynamic Predictors of Postoperative Outcomes
With population aging and limited resources, strategies to improve outcomes after surgery are ever more important. There is a limited understanding of what ranges of hemodynamic variables under anesthesia are associated with…
- Conditions
- Perioperative/Postoperative Complications, Morbidity, Multiple, Surgery, Anesthesia
- Trial name
- NCT04014010
- Testing
- Blood pressure, Heart rate, Use of hemodynamic medications (i.e. special medications for blood pressure)
- Volunteers
- 35,000 people
- Sponsor
- Janny Xue Chen Ke
Mortality After Major Non Cardiac Surgery
Intraoperative Dobutamine Stress Test With Speckle Tracking to Decrease Postoperative Mortality (ISTMO)
Perioperative adverse cardiovascular events are the leading cause of morbidity and mortality after noncardiac surgery. The implications of perioperative cardiac complications on morbidity and mortality, in-hospital and long-term…
- Trial name
- ISTMO (NCT03365726)
- Testing
- Dobutamine stress test with trans-esophageal echocardiography
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Major Non-cardiac Surgery
Effects of Perioperative Administration of Dexamethasone on Postoperative Complications and Mortality After Non-cardiac Major Surgery
Postoperative complications are major healthcare problems and are associated with a reduced short-term and long-term survival after surgery.
- Trial name
- PACMAN (NCT03218553)
- Testing
- Dexamethasone
- Where
- 29 sites in France
- Volunteers
- 1,222 people
- Sponsor
- Nantes University Hospital
Goal Directed Therapy, Postoperative Morbidity
Risk Factors for Postoperative Complications in Major Non-cardiac Surgery: Post-hoc Analysis of the OPHIQUE Multicentre Study
Post-operative morbidity and mortality is related to many factors related to the patient's condition, the intra-operative period and the optimisation of intra-operative haemodynamic and respiratory parameters.
- Conditions
- Goal Directed Therapy, Postoperative Morbidity, Individualised Target, Postopera Mortality
- Trial name
- MULTIPAS (NCT05824260)
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens