Clinical trials: Mortality Prediction
Cardiogenic Shock, Cardiogenic Shock Acute
Prospective Validation of the STOPSHOCK Score - Artificial Intelligence Based Predictive Scoring System to Identify the Risk of Developing Cardiogenic Shock (CS) in Patients Suffering From Acute Coronary Syndrome (ACS)
Cardiogenic shock (CS) is a severe complication of acute coronary syndrome (ACS) with mortality approaching 50% despite the use of percutaneous mechanical circulatory support devices (pMCS).
- Conditions
- Cardiogenic Shock, Cardiogenic Shock Acute, Cardiogenic Shock Post Myocardial Infarction, Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)
- Trial name
- STOPSCHOCK (NCT07090382)
- Where
- Slovakia
- Volunteers
- 1,046 people
- Sponsor
- Premedix Academy
Severe Sepsis
Effect of a Sepsis Prediction Algorithm on Clinical Outcomes
In this clinical outcomes analysis, the effect of a machine learning algorithm for severe sepsis prediction on in-hospital mortality, hospital length of stay, and 30-day readmission was evaluated.
- Trial name
- NCT03960203
- Testing
- InSight
- Volunteers
- 75,147 people, healthy volunteers welcome
- Sponsor
- Dascena
Upper Gastrointestinal Bleeding
Evaluation of Prognostic Scores in Patients With Upper Gastrointestinal Bleeding and Cancer
This is a prospective and observational study to evaluate oncologic patients that presented upper gastrointestinal bleeding with the use of some prognostic scores.
- Trial name
- NCT02508883
- Where
- Brazil
- Volunteers
- 243 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Patients Undergoing Valvular Heart Surgery
A Prediction Model for 1-year Mortality After Valvular Heart Surgery
The investigators aimed to develop a predictive model for mortality incorporating nutritional, inflammatory, and perioperative factors in patients undergoing valvular heart surgery.
- Trial name
- NCT05833256
- Where
- South Korea
- Volunteers
- 2,046 people
- Sponsor
- Yonsei University
Sepsis, Respiratory Failure
Use of Lactate-to-Albumin, CRP-to-Albumin, and Procalcitonin-to-Albumin Ratios to Predict Mortality in ICU Patients
This observational study aims to determine whether three blood test ratios - lactate-to-albumin, CRP-to-albumin, and procalcitonin-to-albumin - can predict in-hospital mortality among critically ill adults.
- Conditions
- Sepsis, Respiratory Failure, Cardiac Arrest, Circulatory Failure
- Trial name
- LAR-CAR-PAR (NCT07242027)
- Where
- Poland
- Volunteers
- 212 people
- Sponsor
- Medical University of Silesia
Acute Respiratory Distress Syndrome (ARDS), Prone Position Ventilation
Machine Learning Prediction of Mortality After Prone Positioning in ARDS
Acute respiratory distress syndrome (ARDS) is a life-threatening condition with high mortality. Prone position ventilation (PPV) is an evidence-based therapy that improves oxygenation and survival in patients with moderate to…
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Prone Position Ventilation, Machine Learning, ICU
- Trial name
- NCT07445061
- Testing
- Prone Position Ventilation
- Where
- China
- Volunteers
- 358 people
- Sponsor
- Shanghai Zhongshan Hospital
COVID19
Optimising Resource Allocation Via Prediction of Outcomes for Covid-19
The investigators plan to use all of the information available within their local NHS hospitals Trust to work out what happens to people admitted with both suspected and proven Covid-19 infections.
- Trial name
- NCT04473105
- Where
- United Kingdom
- Volunteers
- 11,134 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Mortality, Surgery
Mortality Score in Elderly Patients With Colon Cancer
CR-POSSUM is one of the most used surgical scores to predict mortality after colorectal surgery. Its main drawback is the requirement of intraoperative variables, whose collection is time-consuming and prevents from obtaining a…
- Conditions
- Mortality, Surgery, Colon Cancer
- Trial name
- MECC (NCT04538404)
- Testing
- Colon Surgery
- Where
- 2 sites in Italy
- Volunteers
- 385 people
- Sponsor
- University of Bologna
Sepsis, Lactate Blood Increase
Blood Lactate Level for Pre-hospital Orientation of Septic Shock
In the pre-hospital setting, the severity assessment of septic shock is essential to decide the optimal initial in-hospital level of care.
- Trial name
- LAPHSUS (NCT03831685)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hôpital Necker-Enfants Malades
Trauma Injury, Mortality Prediction
Fall Injury Mortality Prediction
This retrospective, multicenter, registry-based cohort study used data from the Pan-Asian Trauma Outcomes Study registry between January 2016 and December 2024.
- Conditions
- Trauma Injury, Mortality Prediction, Fall
- Trial name
- NCT07643051
- Testing
- Prediction model development
- Volunteers
- 58,353 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Trauma, Multiple
TRISS as a Predictor of Trauma Patient Outcomes
The goal of this prospective observational study is to evaluate the predictive utility of the Trauma and Injury Severity Score (TRISS) in determining patient outcomes, including survival and mortality, among trauma patients…
- Trial name
- TRISS/ER (NCT06711536)
- Where
- Iraq
- Volunteers
- 204 people
- Sponsor
- Al-Nahrain University
Acute Variceal Bleeding
Clinical Characteristics Analysis and Prediction Model Establishment of Fatal Esophageal and Gastric Variceal Bleeding
The purpose of this study is to analyze the clinical characteristics of patients with fatal acute variceal bleeding (AVB) and establish a mortality risk prediction model to identify patients at high risk of death after admission…
- Trial name
- NCT05613309
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Renmin Hospital of Wuhan University
Abdominal Surgery, Postoperative Complications
P-POSSUM for Outcomes After Abdominal Surgery
Postoperative complications after abdominal surgery can lead to prolonged recovery, intensive care admission, and death. The P-POSSUM score is a commonly used surgical risk prediction tool, but its performance may vary between…
- Conditions
- Abdominal Surgery, Postoperative Complications, Surgical Risk Prediction, Postoperative Mortality
- Trial name
- PPOSSUM-ABD (NCT07667764)
- Where
- Vietnam
- Volunteers
- 3,000 people
- Sponsor
- Bach Mai Hospital
Bicuspid Aortic Valve
Medtronic Transcatheter Aortic Valve Replacement (TAVR) Low Risk Bicuspid Study
The objective of the trial is to evaluate the procedural safety and efficacy of the Medtronic TAVR system in patients with bicuspid aortic anatomy and severe aortic stenosis at low risk for SAVR
- Trial name
- NCT03635424
- Testing
- Medtronic TAVR Systems
- Where
- 25 sites in United States
- Volunteers
- 150 people
- Sponsor
- Medtronic Cardiovascular
Abdominal Injuries, Wounds and Injuries
Predictors of In-Hospital Mortality in Severe Abdominal Trauma
Severe abdominal trauma is a leading cause of early death from bleeding and of later death from sepsis and organ failure. Clinicians use scoring systems to estimate the risk of dying, but most of these scores were developed and…
- Conditions
- Abdominal Injuries, Wounds and Injuries, Wounds, Nonpenetrating, Wounds, Penetrating
- Trial name
- NCT07843628
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- Minia University
Mallampati Score, Difficult Intubation
Mallampati Score for Prediction and Prognosis of Postoperative Mortality and Morbidity and Safety Profiles of Patients Undergoing Laparoscopic Cholecystectomy in Qassim Region
To predict the majority of Mallampati score for the patients in Qassim region who undergoing Laparoscopic Cholecystectomy Surgery.
- Conditions
- Mallampati Score, Difficult Intubation, Patient Satisfaction, Cholestasis
- Trial name
- NCT06005701
- Where
- Saudi Arabia
- Volunteers
- 470 people
- Sponsor
- Qassim University
Acute Decompensated Heart Failure
Short-term Mortality Prediction by the SOFA Score in Acute Decompensated Heart Failure
Data on the use of sequential organ failure assessment (SOFA) in patients with cardiovascular disease are increasing. Several studies demonstrated that the SOFA score can identify short-term mortality in patients with acute…
- Trial name
- NCT06354426
- Where
- Vietnam
- Volunteers
- 216 people
- Sponsor
- Hanoi Heart Hospital
Heart Failure, Transplant; Failure, Heart
Shear Wave Elastography
In individuals needing a left ventricular assist device (LVAD), right heart failure (RHF) is a serious complication post-surgery, associated with worsened outcomes including mortality.
- Conditions
- Heart Failure, Transplant; Failure, Heart, Decompensated Heart Failure, Fibrosis, Liver
- Trial name
- NCT04493346
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Baylor Research Institute
Wounds and Injuries
Is There a Difference in the Mortality Prediction Performance of Two ICISS Approaches for Trauma Patients Admitted to Hospitals in Urban India?
This study aims to compare the predictive performance of two different approaches of the international classification of disease injury severity score (ICISS) using data from four public university hospitals in urban India.
- Trial name
- NCT02715739
- Testing
- No intervention
- Volunteers
- 3,921 people
- Sponsor
- Karolinska Institutet
Oncology
Using Surveys to Examine the Association of Exposure to ML Mortality Risk Predictions With Medical Oncologists' Prognostic Accuracy and Decision-making
Nearly half of cancer patients in the US will receive care that is inconsistent with their wishes prior to death. Early advanced care planning (ACP) and palliative care improve goal-concordant care and symptoms and reduce…
- Trial name
- NCT06463977
- Testing
- Survey
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Abramson Cancer Center at Penn Medicine